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8VK4
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BU of 8vk4 by Molmil
Structure of mouse RyR1 in complex with S100A1 (high-Ca2+/CFF/ATP dataset)
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, ...
Authors:Weninger, G, Marks, A.R.
Deposit date:2024-01-08
Release date:2024-02-07
Method:ELECTRON MICROSCOPY (3.56 Å)
Cite:Structural insights into the regulation of RyR1 by S100A1.
To Be Published
8VK3
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BU of 8vk3 by Molmil
Structure of mouse RyR1 in complex with S100A1 (EGTA-only dataset)
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Peptidyl-prolyl cis-trans isomerase FKBP1A, Protein S100A1, ...
Authors:Weninger, G, Marks, A.R.
Deposit date:2024-01-08
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Structural insights into the regulation of RyR1 by S100A1
To Be Published
8VJK
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BU of 8vjk by Molmil
Structure of mouse RyR1 (high-Ca2+/CFF/ATP dataset)
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, ...
Authors:Weninger, G, Marks, A.R.
Deposit date:2024-01-07
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:Structural insights into the regulation of RyR1 by S100A1.
To Be Published
8VJJ
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BU of 8vjj by Molmil
Structure of mouse RyR1 (EGTA-only dataset)
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ...
Authors:Weninger, G, Marks, A.R.
Deposit date:2024-01-07
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (2.53 Å)
Cite:Structural insights into the regulation of RyR1 by S100A1.
To Be Published
8UXM
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BU of 8uxm by Molmil
Structure of PKA phosphorylated human RyR2-R420W in the open state in the presence of calcium and calmodulin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin-1, ...
Authors:Miotto, M.C, Marks, A.R.
Deposit date:2023-11-09
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.56 Å)
Cite:Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8UXL
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BU of 8uxl by Molmil
Structure of PKA phosphorylated human RyR2-R420W in the primed state in the presence of calcium and calmodulin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin-1, ...
Authors:Miotto, M.C, Marks, A.R.
Deposit date:2023-11-09
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8UXI
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BU of 8uxi by Molmil
Structure of PKA phosphorylated human RyR2-R420W in the open state in the presence of calcium
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
Authors:Miotto, M.C, Marks, A.R.
Deposit date:2023-11-09
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8UXH
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BU of 8uxh by Molmil
Structure of PKA phosphorylated human RyR2-R420W in the primed state in the presence of calcium
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
Authors:Miotto, M.C, Marks, A.R.
Deposit date:2023-11-09
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.52 Å)
Cite:Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8UXG
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BU of 8uxg by Molmil
Structure of PKA phosphorylated human RyR2-R420W in the closed state in the presence of ARM210
Descriptor: 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
Authors:Miotto, M.C, Marks, A.R.
Deposit date:2023-11-09
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8UXF
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BU of 8uxf by Molmil
Structure of PKA phosphorylated human RyR2-R420W in the primed state
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
Authors:Miotto, M.C, Marks, A.R.
Deposit date:2023-11-09
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8UXE
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BU of 8uxe by Molmil
Structure of PKA phosphorylated human RyR2-R420Q in the closed state in the presence of ARM210
Descriptor: 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
Authors:Miotto, M.C, Marks, A.R.
Deposit date:2023-11-09
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8UXC
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BU of 8uxc by Molmil
Structure of PKA phosphorylated human RyR2-R420Q in the primed state
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
Authors:Miotto, M.C, Marks, A.R.
Deposit date:2023-11-09
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8UQ5
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BU of 8uq5 by Molmil
Structure of human RyR2-S2808D in the primed state in the presence of Rapamycin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Ryanodine receptor 2, ZINC ION
Authors:Miotto, M.C, Marks, A.R.
Deposit date:2023-10-23
Release date:2023-11-15
Method:ELECTRON MICROSCOPY (3.96 Å)
Cite:Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8UQ4
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BU of 8uq4 by Molmil
Structure of human RyR2-S2808D in the subprimed state in the presence of H2O2/NOC-12/GSH
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
Authors:Miotto, M.C, Marks, A.R.
Deposit date:2023-10-23
Release date:2023-11-15
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8UQ3
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BU of 8uq3 by Molmil
Structure of human RyR2-S2808D in the closed state in the presence of ARM210
Descriptor: 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
Authors:Miotto, M.C, Marks, A.R.
Deposit date:2023-10-23
Release date:2023-11-15
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8UQ2
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BU of 8uq2 by Molmil
Structure of human RyR2-S2808D in the subprimed state
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
Authors:Miotto, M.C, Marks, A.R.
Deposit date:2023-10-23
Release date:2023-11-15
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8SF0
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BU of 8sf0 by Molmil
Cryo-EM Structure of RyR1 + cAMP (Local Refinement of TMD)
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Ryanodine receptor 1, ZINC ION
Authors:Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
Deposit date:2023-04-10
Release date:2023-05-24
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEZ
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BU of 8sez by Molmil
Cryo-EM Structure of RyR1 + Adenine (Local Refinement of TMD)
Descriptor: ADENINE, Ryanodine receptor 1, ZINC ION
Authors:Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
Deposit date:2023-04-10
Release date:2023-05-24
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEY
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BU of 8sey by Molmil
Cryo-EM Structure of RyR1 + Adenosine (Local Refinement of TMD)
Descriptor: ADENOSINE, Ryanodine receptor 1, ZINC ION
Authors:Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
Deposit date:2023-04-10
Release date:2023-05-24
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEX
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BU of 8sex by Molmil
Cryo-EM Structure of RyR1 + AMP (Local Refinement of TMD)
Descriptor: ADENOSINE MONOPHOSPHATE, Ryanodine receptor 1, ZINC ION
Authors:Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
Deposit date:2023-04-10
Release date:2023-05-24
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEW
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BU of 8sew by Molmil
Cryo-EM Structure of RyR1 + ADP (Local Refinement of TMD)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Ryanodine receptor 1, ZINC ION
Authors:Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
Deposit date:2023-04-10
Release date:2023-05-24
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEV
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BU of 8sev by Molmil
Cryo-EM Structure of RyR1 + ATP-gamma-S (Local Refinement of TMD)
Descriptor: PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Ryanodine receptor 1, ZINC ION
Authors:Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
Deposit date:2023-04-10
Release date:2023-05-24
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEU
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BU of 8seu by Molmil
Cryo-EM Structure of RyR1 (Local Refinement of TMD)
Descriptor: Ryanodine receptor 1, ZINC ION
Authors:Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
Deposit date:2023-04-10
Release date:2023-05-24
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SET
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BU of 8set by Molmil
Cryo-EM Structure of RyR1 + cAMP
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ...
Authors:Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
Deposit date:2023-04-10
Release date:2023-05-24
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SES
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BU of 8ses by Molmil
Cryo-EM Structure of RyR1 + Adenine
Descriptor: ADENINE, Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ...
Authors:Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
Deposit date:2023-04-10
Release date:2023-05-24
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (3.98 Å)
Cite:Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023

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PDB entries from 2024-03-27

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