2AFJ
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SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 2 (SSB-2)
Descriptor:gene rich cluster, C9 gene
Authors:Masters, S.L., Yao, S., Willson, T.A., Zhang, J.G., Palmer, K.R., Smith, B.J., Babon, J.J., Nicola, N.A., Norton, R.S., Nicholson, S.E.
Deposit date:2005-07-26
Release date:2006-01-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues
Nat.Struct.Mol.Biol., 13, 2006
2IHS
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CRYSTAL STRUCTURE OF THE B30.2/SPRY DOMAIN OF GUSTAVUS IN COMPLEX WITH A 20-RESIDUE VASA PEPTIDE
Descriptor:CG2944-PF, isoform F, 20-mer from ATP-dependent RNA helicase vasa
Authors:Woo, J.S., Park, S.Y., Oh, B.H.
Deposit date:2006-09-27
Release date:2007-01-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis for Protein Recognition by B30.2/SPRY Domains
Mol.Cell, 24, 2006
2JK9
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THE STRUCTURE OF SPLA-RYANODINE RECEPTOR DOMAIN AND SOCS BOX CONTAINING 1 IN COMPLEX WITH A PAR-4 PEPTIDE
Descriptor:SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 1, PRKC APOPTOSIS WT1 REGULATOR PROTEIN
Authors:Filippakopoulos, P., Bullock, A., Keates, T., Savitsky, P., Murray, J.W., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Wickstroem, M., Bountra, C., Knapp, S.
Deposit date:2008-08-22
Release date:2008-09-16
Last modified:2012-12-05
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structural Basis for Par-4 Recognition by the Spry Domain-and Socs Box-Containing Proteins Spsb1, Spsb2, and Spsb4.
J.Mol.Biol., 401, 2010
2LM3
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STRUCTURE OF THE RHESUS MONKEY TRIM5ALPHA PRYSPRY DOMAIN
Descriptor:Tripartite motif-containing protein 5
Authors:Biris, N., Yang, Y., Taylor, A.B., Tomashevski, A., Guo, M., Hart, P.J., Diaz-Griffero, F., Ivanov, D.N.
Deposit date:2011-11-21
Release date:2012-08-08
Last modified:2013-06-19
Method:SOLUTION NMR
Cite:Structure of the rhesus monkey TRIM5alpha PRYSPRY domain, the HIV capsid recognition module.
Proc.Natl.Acad.Sci.USA, 109, 2012
2V24
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STRUCTURE OF THE HUMAN SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN SSB-4
Descriptor:SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 4, NICKEL (II) ION
Authors:Uppenberg, J., Bullock, A., Keates, T., Savitsky, P., Pike, A.C.W., Ugochukwu, E., Bunkoczi, G., von Delft, F., Weigelt, J., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Knapp, S.
Deposit date:2007-05-31
Release date:2007-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis for Par-4 Recognition by the Spry Domain-and Socs Box-Containing Proteins Spsb1, Spsb2, and Spsb4.
J.Mol.Biol., 401, 2010
2YYO
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CRYSTAL STURCTURE OF HUMAN SPRY DOMAIN
Descriptor:SPRY domain-containing protein 3
Authors:Kishishita, S., Uchikubo-Kamo, T., Murayama, K., Terada, T., Chen, L., Fu, Z.Q., Chrzas, J., Shirouzu, M., Wang, B.C., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-30
Release date:2008-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal sturcture of human SPRY domain
To be Published
3EK9
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SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 2: CRYSTAL STRUCTURE AND RESIDUES CRITICAL FOR PROTEIN BINDING
Descriptor:SPRY domain-containing SOCS box protein 2, GLYCEROL
Authors:Kuang, Z., Yao, S., Xu, Y., Garrett, T.J.P., Norton, R.S.
Deposit date:2008-09-19
Release date:2009-02-24
Last modified:2012-02-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:SPRY domain-containing SOCS box protein 2: crystal structure and residues critical for protein binding.
J.Mol.Biol., 386, 2009
3EMW
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CRYSTAL STRUCTURE OF HUMAN SPLA/RYANODINE RECEPTOR DOMAIN AND SOCS BOX CONTAINING 2 (SPSB2) IN COMPLEX WITH A 20-RESIDUE VASA PEPTIDE
Descriptor:SPRY domain-containing SOCS box protein 2, Peptide (VASA), 1,2-ETHANEDIOL
Authors:Filippakopoulos, P., Sharpe, T., Keates, T., Murray, J.W., Savitsky, P., Roos, A.K., Pike, A.C.W., Von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Knapp, S., Bullock, A., Structural Genomics Consortium (SGC)
Deposit date:2008-09-25
Release date:2008-10-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4.
J.Mol.Biol., 401, 2010
3F2O
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CRYSTAL STRUCTURE OF HUMAN SPLA/RYANODINE RECEPTOR DOMAIN AND SOCS BOX CONTAINING 1 (SPSB1) IN COMPLEX WITH A 20-RESIDUE VASA PEPTIDE
Descriptor:SPRY domain-containing SOCS box protein 1, 20-mer peptide from ATP-dependent RNA helicase vasa
Authors:Filippakopoulos, P., Sharpe, T., Keates, T., Murray, J.W., Savitsky, P., Roos, A., Pike, A.C.W., Von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Knapp, S., Bullock, A., Structural Genomics Consortium (SGC)
Deposit date:2008-10-30
Release date:2008-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4.
J.Mol.Biol., 401, 2010
3UV9
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STRUCTURE OF THE RHESUS MONKEY TRIM5ALPHA DELTAV1 PRYSPRY DOMAIN
Descriptor:Tripartite motif-containing protein 5
Authors:Biris, N., Yang, Y., Taylor, A.B., Tomashevskii, A., Guo, M., Hart, P.J., Diaz-Griffero, F., Ivanov, D.
Deposit date:2011-11-29
Release date:2012-08-08
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (1.549 Å)
Cite:Structure of the rhesus monkey TRIM5alpha PRYSPRY domain, the HIV capsid recognition module.
Proc.Natl.Acad.Sci.USA, 109, 2012
4P9I
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CRYSTAL STRUCTURE OF MOUSE RYANODINE RECEPTOR 2 SPRY2 DOMAIN (1080-1253)
Descriptor:Ryanodine receptor 2
Authors:Lau, K., Van Petegem, F.
Deposit date:2014-04-04
Release date:2014-11-05
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.3401 Å)
Cite:Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.
Nat Commun, 5, 2014
4P9J
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CRYSTAL STRUCTURE OF RABBIT RYANODINE RECEPTOR 1 SPRY2 DOMAIN (1070-1246)
Descriptor:Ryanodine receptor 1
Authors:Lau, K., Van Petegem, F.
Deposit date:2014-04-04
Release date:2014-11-05
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.
Nat Commun, 5, 2014
4P9L
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CRYSTAL STRUCTURE OF MOUSE RYANODINE RECEPTOR 2 SPRY2 DOMAIN (1080-1253) DISEASE MUTANT A1107M
Descriptor:Ryanodine receptor 2
Authors:Lau, K., Van Petegem, F.
Deposit date:2014-04-04
Release date:2014-11-05
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.4361 Å)
Cite:Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.
Nat Commun, 5, 2014
4QT6
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CRYSTAL STRUCTURE OF THE SPRY DOMAIN OF HUMAN HERC1
Descriptor:Probable E3 ubiquitin-protein ligase HERC1, FORMAMIDE, UNKNOWN ATOM OR ION
Authors:Dong, A., Hu, J., Guan, X., Wernimont, A., Li, Y., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Tong, Y., Structural Genomics Consortium (SGC)
Deposit date:2014-07-07
Release date:2015-01-07
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Crystal structure of the SPRY domain of human HERC1
To be Published
4XW3
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CRYSTAL STRUCTURE OF THE SPRY DOMAIN OF THE HUMAN DEAD-BOX PROTEIN DDX1
Descriptor:ATP-dependent RNA helicase DDX1
Authors:Kellner, J.N., Meinhart, A.
Deposit date:2015-01-28
Release date:2015-09-09
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the SPRY domain of the human RNA helicase DDX1, a putative interaction platform within a DEAD-box protein.
Acta Crystallogr.,Sect.F, 71, 2015
5C33
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CRYSTAL STRUCTURE OF MOUSE RYANODINE RECEPTOR 2 SPRY1 DOMAIN
Descriptor:Ryanodine receptor 2, ISOPROPYL ALCOHOL, CHLORIDE ION
Authors:Yuchi, Z., Van Petegem, F.
Deposit date:2015-06-16
Release date:2015-08-05
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Crystal structures of ryanodine receptor SPRY1 and tandem-repeat domains reveal a critical FKBP12 binding determinant.
Nat Commun, 6, 2015
5JI7
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THE CRYSTAL STRUCTURE OF IUS-SPRY DOMAIN FROM RANBPM/9
Descriptor:Ran-binding protein 9
Authors:Hong, S.K., Kim, K.-H., Kim, E.E.
Deposit date:2016-04-22
Release date:2016-11-09
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Structural Basis for the Interaction between the IUS-SPRY Domain of RanBPM and DDX-4 in Germ Cell Development.
J.Mol.Biol., 428, 2016
5JI9
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THE CRYSTAL STRUCTURE OF IUS-SPRY DOMAIN FROM RANBPM/9
Descriptor:Ran-binding protein 9
Authors:Hong, S.K., Kim, K.-H., Kim, E.E.
Deposit date:2016-04-22
Release date:2016-11-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for the Interaction between the IUS-SPRY Domain of RanBPM and DDX-4 in Germ Cell Development.
J.Mol.Biol., 428, 2016
5JIA
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THE CRYSTAL STRUCTURE OF IUS-SPRY DOMAIN FROM RANBP10
Descriptor:Ran-binding protein 10, IMIDAZOLE
Authors:Hong, S.K., Kim, K.-H., Kim, E.E.
Deposit date:2016-04-22
Release date:2016-11-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for the Interaction between the IUS-SPRY Domain of RanBPM and DDX-4 in Germ Cell Development.
J.Mol.Biol., 428, 2016
5JIU
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THE CRYSTAL STRUCTURE OF RANBPM/9 IUS-SPRY DOMAIN IN COMPLEX WITH DDX-4 PEPTIDE
Descriptor:Ran-binding protein 9, Probable ATP-dependent RNA helicase DDX4, CHLORIDE ION
Authors:Hong, S.K., Kim, K.-H., Kim, E.E.
Deposit date:2016-04-22
Release date:2016-11-09
Method:X-RAY DIFFRACTION (2.054 Å)
Cite:Structural Basis for the Interaction between the IUS-SPRY Domain of RanBPM and DDX-4 in Germ Cell Development.
J.Mol.Biol., 428, 2016
5VSN
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CRYSTAL STRUCTURE OF MOUSE RYANODINE RECEPTOR 2 SPRY2 DOMAIN (1080-1253) DISEASE MUTANT P1124L
Descriptor:Ryanodine receptor 2, GLYCEROL, POTASSIUM ION
Authors:Yuchi, Z., Van Petegem, F.
Deposit date:2017-05-12
Release date:2018-05-23
Method:X-RAY DIFFRACTION (1.439 Å)
Cite:Novel Ryanodine Receptor Mutation Associated with Hypertrophic Cardiomyopathy Induces Cardiac Remodeling and Arrhythmia in Mice
To be Published
5XN3
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CRYSTAL STRUCTURE OF SPSB2 IN COMPLEX WITH A RATIONAL DESIGNED RGD CONTAINING CYCLIC PEPTIDE INHIBITOR OF SPSB2-INOS INTERACTION
Descriptor:SPRY domain-containing SOCS box protein 2, cR8 peptide from NOS2
Authors:You, T., Kuang, Z.
Deposit date:2017-05-17
Release date:2017-06-14
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Crystal structure of SPSB2 in complex with a rational designed RGD-containing cyclic peptide inhibitor of SPSB2-iNOS interaction.
Biochem. Biophys. Res. Commun., 489, 2017
2FBE
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CRYSTAL STRUCTURE OF THE PRYSPRY-DOMAIN
Descriptor:PREDICTED: similar to ret finger protein-like 1
Authors:Gruetter, C., Briand, C., Capitani, G., Mittl, P.R., Gruetter, M.G.
Deposit date:2005-12-09
Release date:2006-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Structure of the PRYSPRY-domain: Implications for autoinflammatory diseases
Febs Lett., 580, 2006
2FNJ
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CRYSTAL STRUCTURE OF A B30.2/SPRY DOMAIN-CONTAINING PROTEIN GUSTAVUS IN COMPLEX WITH ELONGIN B AND ELONGIN C
Descriptor:CG2944-PF, isoform F, Transcription elongation factor B polypeptide 2, ...
Authors:Woo, J.S., Oh, B.H.
Deposit date:2006-01-11
Release date:2006-03-21
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional insights into the B30.2/SPRY domain
Embo J., 25, 2006
2VOK
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MURINE TRIM21
Descriptor:52 KDA RO PROTEIN
Authors:Keeble, A.H., Khan, Z., Forster, A., James, L.C.
Deposit date:2008-02-19
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Trim21 is an Igg Receptor that is Structurally, Thermodynamically, and Kinetically Conserved.
Proc.Natl.Acad.Sci.USA, 105, 2008
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