1AGR
| COMPLEX OF ALF4-ACTIVATED GI-ALPHA-1 WITH RGS4 | Descriptor: | CITRIC ACID, GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Tesmer, J.J.G, Sprang, S.R. | Deposit date: | 1997-03-25 | Release date: | 1997-06-16 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis. Cell(Cambridge,Mass.), 89, 1997
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1CMZ
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1EMU
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1DK8
| CRYSTAL STRUCTURE OF THE RGS-HOMOLOGOUS DOMAIN OF AXIN | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, AXIN, GLYCEROL, ... | Authors: | Spink, K.E, Polakis, P, Weis, W.I. | Deposit date: | 1999-12-06 | Release date: | 2000-07-12 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Structural basis of the Axin-adenomatous polyposis coli interaction. EMBO J., 19, 2000
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1EZT
| HIGH-RESOLUTION SOLUTION STRUCTURE OF FREE RGS4 BY NMR | Descriptor: | REGULATOR OF G-PROTEIN SIGNALING 4 | Authors: | Moy, F.J, Chanda, P.K, Cockett, M.I, Edris, W, Jones, P.G, Mason, K, Semus, S, Powers, R. | Deposit date: | 2000-05-11 | Release date: | 2001-01-15 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | NMR structure of free RGS4 reveals an induced conformational change upon binding Galpha. Biochemistry, 39, 2000
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1EZY
| HIGH-RESOLUTION SOLUTION STRUCTURE OF FREE RGS4 BY NMR | Descriptor: | REGULATOR OF G-PROTEIN SIGNALING 4 | Authors: | Moy, F.J, Chanda, P.K, Cockett, M.I, Edris, W, Jones, P.G, Mason, K, Semus, S, Powers, R. | Deposit date: | 2000-05-12 | Release date: | 2001-01-15 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | NMR structure of free RGS4 reveals an induced conformational change upon binding Galpha. Biochemistry, 39, 2000
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1FQK
| CRYSTAL STRUCTURE OF THE HETERODIMERIC COMPLEX OF THE RGS DOMAIN OF RGS9, AND THE GT/I1 CHIMERA ALPHA SUBUNIT [(RGS9)-(GT/I1ALPHA)-(GDP)-(ALF4-)-(MG2+)] | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(t) subunit alpha-1,Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(t) subunit alpha-1, MAGNESIUM ION, ... | Authors: | Slep, K.C, Kercher, M.A, He, W, Cowan, C.W, Wensel, T.G, Sigler, P.B. | Deposit date: | 2000-09-05 | Release date: | 2001-02-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A. Nature, 409, 2001
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1FQJ
| CRYSTAL STRUCTURE OF THE HETEROTRIMERIC COMPLEX OF THE RGS DOMAIN OF RGS9, THE GAMMA SUBUNIT OF PHOSPHODIESTERASE AND THE GT/I1 CHIMERA ALPHA SUBUNIT [(RGS9)-(PDEGAMMA)-(GT/I1ALPHA)-(GDP)-(ALF4-)-(MG2+)] | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(t) subunit alpha-1,Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(t) subunit alpha-1, MAGNESIUM ION, ... | Authors: | Slep, K.C, Kercher, M.A, He, W, Cowan, C.W, Wensel, T.G, Sigler, P.B. | Deposit date: | 2000-09-05 | Release date: | 2001-02-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A. Nature, 409, 2001
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1FQI
| RGS9 RGS DOMAIN | Descriptor: | REGULATOR OF G-PROTEIN SIGNALING 9 | Authors: | Slep, K.C, Kercher, M.A, He, W, Cowan, C.W, Wensel, T.G, Sigler, P.B. | Deposit date: | 2000-09-05 | Release date: | 2001-02-28 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A. Nature, 409, 2001
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1OMW
| Crystal Structure of the complex between G Protein-Coupled Receptor Kinase 2 and Heterotrimeric G Protein beta 1 and gamma 2 subunits | Descriptor: | G-protein coupled receptor kinase 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1 | Authors: | Lodowski, D.T, Pitcher, J.A, Capel, W.D, Lefkowitz, R.J, Tesmer, J.J.G. | Deposit date: | 2003-02-26 | Release date: | 2003-06-03 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Keeping G proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and G-Beta-Gamma Science, 300, 2003
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2BT2
| Structure of the regulator of G-protein signaling 16 | Descriptor: | REGULATOR OF G-PROTEIN SIGNALING 16 | Authors: | Bunkoczi, G, Haroniti, A, Longman, E, Niesen, F, Soundararajan, M, Ball, L.J, von Delft, F, Doyle, D.A, Arrowsmith, C, Edwards, A, Sundstrom, M. | Deposit date: | 2005-05-25 | Release date: | 2005-06-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Diversity in the Rgs Domain and its Interaction with Heterotrimeric G Protein Alpha- Subunits. Proc.Natl.Acad.Sci.USA, 105, 2008
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2BV1
| Regulator of G-protein Signalling 1 (Human) | Descriptor: | REGULATOR OF G-PROTEIN SIGNALLING 1 | Authors: | Elkins, J.M, Yang, X, Soundararajan, M, Schoch, G.A, Haroniti, A, Sundstrom, M, Edwards, A, Arrowsmith, C, Doyle, D.A. | Deposit date: | 2005-06-20 | Release date: | 2005-06-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc. Natl. Acad. Sci. U.S.A., 105, 2008
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1ZV4
| Structure of the Regulator of G-Protein Signaling 17 (RGSZ2) | Descriptor: | Regulator of G-protein signaling 17 | Authors: | Schoch, G.A, Jansson, A, Elkins, J.M, Haroniti, A, Niesen, F.H, Bunkoczi, G, Lee, W.H, Turnbull, A.P, Yang, X, Sundstrom, M, Arrowsmith, C, Edwards, A, Marsden, B, Gileadi, O, Ball, L, von Delft, F, Doyle, D.A, Structural Genomics Consortium (SGC) | Deposit date: | 2005-06-01 | Release date: | 2005-06-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105, 2008
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1YM7
| G Protein-Coupled Receptor Kinase 2 (GRK2) | Descriptor: | Beta-adrenergic receptor kinase 1 | Authors: | Lodowski, D.T, Barnhill, J.F, Pyskadlo, R.M, Ghirlando, R, Sterne-Marr, R, Tesmer, J.J.G. | Deposit date: | 2005-01-20 | Release date: | 2005-07-05 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | The role of Gbetagamma and domain interfaces in the activation of G protein-coupled receptor kinase 2 Biochemistry, 44, 2005
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2A72
| Structure of the regulator of G-protein signaling domain of RGS7 | Descriptor: | CHLORIDE ION, Regulator of G-protein signalling 7 | Authors: | Schoch, G.A, Johansson, C, Phillips, C, Debreczeni, J, Smee, C, Elkins, J.M, Sundstrom, M, Edwards, A, Arrowsmith, C, von Delft, F, Gileadi, O, Doyle, D.A, Structural Genomics Consortium (SGC) | Deposit date: | 2005-07-04 | Release date: | 2005-07-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105, 2008
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2AF0
| Structure of the Regulator of G-Protein Signaling Domain of RGS2 | Descriptor: | Regulator of G-protein signaling 2 | Authors: | Papagrigoriou, E, Johannson, C, Phillips, C, Smee, C, Elkins, J.M, Weigelt, J, Arrowsmith, C, Edwards, A, Sundstrom, M, Von Delft, F, Doyle, D.A, Structural Genomics Consortium (SGC) | Deposit date: | 2005-07-25 | Release date: | 2005-08-02 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105, 2008
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2CRP
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2ES0
| Structure of the regulator of G-protein signaling domain of RGS6 | Descriptor: | regulator of G-protein signalling 6 | Authors: | Schoch, G.A, Phillips, C, Turnbull, A, Niesen, F, Johansson, C, Elkins, J.M, Longman, E, Gilealdi, C, Sobott, F, Ball, L, Sundstrom, M, Edwards, A, Arrowsmith, C, von Delft, F, Doyle, D.A, Structural Genomics Consortium (SGC) | Deposit date: | 2005-10-25 | Release date: | 2005-11-29 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105, 2008
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2BCJ
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2ACX
| Crystal Structure of G protein coupled receptor kinase 6 bound to AMPPNP | Descriptor: | G protein-coupled receptor kinase 6, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Lodowski, D.T, Tesmer, V.M, Benovic, J.L, Tesmer, J.J. | Deposit date: | 2005-07-19 | Release date: | 2006-04-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The Structure of G Protein-coupled Receptor Kinase (GRK)-6 Defines a Second Lineage of GRKs. J.Biol.Chem., 281, 2006
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2GTP
| Crystal structure of the heterodimeric complex of human RGS1 and activated Gi alpha 1 | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i), alpha-1 subunit, ... | Authors: | Soundararajan, M, Turnbull, A.P, Ugochukwu, E, Gorrec, F, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC) | Deposit date: | 2006-04-28 | Release date: | 2006-05-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105, 2008
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2DLR
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2JM5
| Solution Structure of the RGS domain from human RGS18 | Descriptor: | Regulator of G-protein signaling 18 | Authors: | Higman, V.A, Leidert, M, Bray, J, Elkins, J, Soundararajan, M, Doyle, D.A, Gileadi, C, Phillips, C, Schoch, G, Yang, X, Brockmann, C, Schmieder, P, Diehl, A, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Oschkinat, H, Ball, L.J, Structural Genomics Consortium (SGC) | Deposit date: | 2006-10-11 | Release date: | 2006-10-24 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105, 2008
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2I59
| Solution structure of RGS10 | Descriptor: | Regulator of G-protein signaling 10 | Authors: | Fedorov, O, Higman, V.A, Diehl, A, Leidert, M, Lemak, A, Schmieder, P, Oschkinat, H, Elkins, J, Soundarajan, M, Doyle, D.A, Arrowsmith, C, Sundstrom, M, Weigelt, J, Edwards, A, Ball, L.J, Structural Genomics Consortium (SGC) | Deposit date: | 2006-08-24 | Release date: | 2006-10-31 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105, 2008
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2IHD
| Crystal structure of Human Regulator of G-protein signaling 8, RGS8 | Descriptor: | CHLORIDE ION, Regulator of G-protein signaling 8 | Authors: | Turnbull, A.P, Papagrigoriou, E, Ugochukwu, E, Salah, E, Gileadi, C, Burgess, N, Bhatia, C, Gileadi, O, Bray, J, Elkins, J, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC) | Deposit date: | 2006-09-26 | Release date: | 2006-11-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105, 2008
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