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8T4C
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BU of 8t4c by Molmil
Membrane-associated thioredoxin oxidoreductase FetE from Campylobacter jejuni
Descriptor: GLYCEROL, SULFATE ION, Thioredoxin oxidoreductase
Authors:Chan, A.C, Murphy, M.E.
Deposit date:2023-06-09
Release date:2023-08-09
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Dissecting components of the Campylobacter jejuni fetMP-fetABCDEF gene cluster in iron scavenging.
Biorxiv, 2023
8HLA
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BU of 8hla by Molmil
Heteromeric ring comprised of peroxiredoxin from Thermococcus kodakaraensis (TkPrx) F42C/C46S/C205S/C211S mutant modified with 2-(bromoacetyl)naphthalene (Naph@TkPrx*F42C) and TkPrx C46S/F76C/C205S/C211S mutant modified with 2-(bromoacetyl)naphthalene (Naph@TkPrx*F76C) (Naph@(MIX|3:3))
Descriptor: 1-naphthalen-2-ylethanone, Peroxiredoxin
Authors:Himiyama, T, Hamaguchi, T, Yonekura, K, Nakamura, T.
Deposit date:2022-11-29
Release date:2023-03-22
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:Unnaturally Distorted Hexagonal Protein Ring Alternatingly Reorganized from Two Distinct Chemically Modified Proteins.
Bioconjug.Chem., 2023
8HH0
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BU of 8hh0 by Molmil
Peroxiredoxin from Thermococcus kodakaraensis (TkPrx) F42C/C46S/C205S/C211S mutant modified with 2-(bromoacetyl)naphthalene (Naph@TkPrx*F42C)
Descriptor: 1-naphthalen-2-ylethanone, Peroxiredoxin
Authors:Himiyama, T, Hamaguchi, T, Yonekura, K, Nakamura, T.
Deposit date:2022-11-16
Release date:2023-03-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Unnaturally Distorted Hexagonal Protein Ring Alternatingly Reorganized from Two Distinct Chemically Modified Proteins.
Bioconjug.Chem., 2023
8EKY
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BU of 8eky by Molmil
Cryo-EM structure of the human PRDX4-ErP46 complex
Descriptor: Peroxiredoxin-4, Thioredoxin domain-containing protein 5
Authors:Su, C.C.
Deposit date:2022-09-22
Release date:2023-05-03
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:High-resolution structural-omics of human liver enzymes.
Cell Rep, 42, 2023
8EKW
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BU of 8ekw by Molmil
Cryo-EM structure of human PRDX4
Descriptor: Peroxiredoxin-4
Authors:Su, C.C.
Deposit date:2022-09-22
Release date:2023-05-03
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:High-resolution structural-omics of human liver enzymes.
Cell Rep, 42, 2023
7WEU
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BU of 7weu by Molmil
Crystal structure of Peroxiredoxin I in complex with compound 19-048
Descriptor: Peroxiredoxin-1, UNKNOWN LIGAND
Authors:Zhang, H, Luo, C.
Deposit date:2021-12-24
Release date:2022-12-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Celastrol suppresses colorectal cancer via covalent targeting peroxiredoxin 1.
Signal Transduct Target Ther, 8, 2023
7WET
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BU of 7wet by Molmil
Crystal structure of Peroxiredoxin I in complex with the inhibitor Cela
Descriptor: (2R,4aS,6aS,12bR,14aS,14bR)-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylic acid, Peroxiredoxin-1
Authors:Zhang, H, Luo, C.
Deposit date:2021-12-24
Release date:2022-12-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Celastrol suppresses colorectal cancer via covalent targeting peroxiredoxin 1.
Signal Transduct Target Ther, 8, 2023
7E4U
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BU of 7e4u by Molmil
Crystal structure of Peroxiredoxin-1
Descriptor: CALCIUM ION, GLYCEROL, Peroxiredoxin 1
Authors:Ahmed, S, Mok, Y.K, Jobichen, C.
Deposit date:2021-02-15
Release date:2022-02-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of Peroxiredoxin-1
To Be Published
7LJ1
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BU of 7lj1 by Molmil
Human Prx1-Srx Decameric Complex
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
Authors:Forshaw, T.E, Reisz, J.A, Nelson, K.J, Gumpena, R, Lawson, J.R, Jonsson, T, Wu, H, Clodfelter, J.E, Johnson, L, Furdui, C.M, Lowther, W.T.
Deposit date:2021-01-28
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Specificity of Human Sulfiredoxin for Reductant and Peroxiredoxin Oligomeric State.
Antioxidants (Basel), 10, 2021
7KUU
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BU of 7kuu by Molmil
LsfA from P. aeruginosa, a 1-Cys Prx in Sulfonic acid form
Descriptor: Alkyl hydroperoxide reductase C
Authors:AIeixo-Silva, R.L, Domingos, R.M, Netto, L.E.S.
Deposit date:2020-11-25
Release date:2021-12-15
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of LsfA, a 1-Cys Prx in sulfonic acid form
To Be Published
7KJ0
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BU of 7kj0 by Molmil
hyperoxidized human peroxiredoxin 2
Descriptor: Peroxiredoxin-2
Authors:Kean, K.M, Karplus, P.A.
Deposit date:2020-10-25
Release date:2021-03-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Modifying the resolving cysteine affects the structure and hydrogen peroxide reactivity of peroxiredoxin 2.
J.Biol.Chem., 296, 2021
7KIZ
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BU of 7kiz by Molmil
reduced human peroxiredoxin 2
Descriptor: Peroxiredoxin-2
Authors:Kean, K.M, Karplus, P.A.
Deposit date:2020-10-25
Release date:2021-03-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Modifying the resolving cysteine affects the structure and hydrogen peroxide reactivity of peroxiredoxin 2.
J.Biol.Chem., 296, 2021
7KJ1
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BU of 7kj1 by Molmil
human peroxiredoxin 2 - C172S mutant
Descriptor: Peroxiredoxin-2
Authors:Kean, K.M, Karplus, P.A.
Deposit date:2020-10-25
Release date:2021-03-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Modifying the resolving cysteine affects the structure and hydrogen peroxide reactivity of peroxiredoxin 2.
J.Biol.Chem., 296, 2021
7CQJ
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BU of 7cqj by Molmil
Peroxiredoxin from Aeropyrum pernix K1 (ApPrx) C50S/K84A/C207S/C213S mutant (ApPrx*K84A)
Descriptor: Peroxiredoxin
Authors:Himiyama, T, Nakamura, T.
Deposit date:2020-08-11
Release date:2020-12-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Rebuilding Ring-Type Assembly of Peroxiredoxin by Chemical Modification.
Bioconjug.Chem., 32, 2021
7C87
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BU of 7c87 by Molmil
Peroxiredoxin from Aeropyrum pernix K1 (ApPrx) C50S/F80C/C207S/C213S mutant (ApPrx*F80C)
Descriptor: CITRIC ACID, Peroxiredoxin
Authors:Himiyama, T, Nakamura, T.
Deposit date:2020-05-29
Release date:2020-12-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Rebuilding Ring-Type Assembly of Peroxiredoxin by Chemical Modification.
Bioconjug.Chem., 32, 2021
7C89
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BU of 7c89 by Molmil
Peroxiredoxin from Aeropyrum pernix K1 (ApPrx) C50S/F80C/C207S/C213S mutant modified with 2-bromoacetophenone(Ph@ApPrx*)
Descriptor: 2-bromanyl-1-phenyl-ethanone, CITRATE ANION, Peroxiredoxin
Authors:Himiyama, T, Nakamura, T.
Deposit date:2020-05-29
Release date:2020-12-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Rebuilding Ring-Type Assembly of Peroxiredoxin by Chemical Modification.
Bioconjug.Chem., 32, 2021
7C8A
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BU of 7c8a by Molmil
Peroxiredoxin from Aeropyrum pernix K1 (ApPrx) C50S/F80C/C207S/C213S mutant modified with 2-(bromoacetyl)naphthalene(Naph@ApPrx*)
Descriptor: 1-naphthalen-2-ylethanone, CITRIC ACID, Peroxiredoxin
Authors:Himiyama, T, Nakamura, T.
Deposit date:2020-05-29
Release date:2020-12-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Rebuilding Ring-Type Assembly of Peroxiredoxin by Chemical Modification.
Bioconjug.Chem., 32, 2021
7BZ6
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BU of 7bz6 by Molmil
Mycobacterium bovis AhpC
Descriptor: Alkyl hydroperoxide reductase C peptide
Authors:Chong, S.M.S, Neelagandan, K, Gruber, G.
Deposit date:2020-04-27
Release date:2021-03-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.302 Å)
Cite:Residues of helix alpha2 are critical for catalytic efficiency of mycobacterial alkylhydroperoxide reductase subunit C.
Febs Lett., 594, 2020
6UTL
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BU of 6utl by Molmil
Yeast Thiol Specific antoxidant 2 with C171S mutation and catalytic cysteine alkylated with iodoacetamide
Descriptor: Peroxiredoxin TSA2
Authors:Tairum, C.A, Bannitz-Fernandes, R, Tonoli, C.C.C, Murakami, M.T, de Oliveira, M.A, Netto, L.E.S.
Deposit date:2019-10-29
Release date:2020-07-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Reduction of sulfenic acids by ascorbate in proteins, connecting thiol-dependent to alternative redox pathways.
Free Radic Biol Med, 156, 2020
6KRQ
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BU of 6krq by Molmil
Peroxiredoxin from Aeropyrum pernix K1 (ApPrx) 0Cys F80A mutant
Descriptor: CITRIC ACID, Peroxiredoxin
Authors:Himiyama, T, Nakamura, T.
Deposit date:2019-08-22
Release date:2020-07-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Disassembly of the ring-type decameric structure of peroxiredoxin from Aeropyrum pernix K1 by amino acid mutation.
Protein Sci., 29, 2020
6KRP
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BU of 6krp by Molmil
Peroxiredoxin from Aeropyrum pernix K1 (ApPrx) 0Cys W88A mutant
Descriptor: CITRIC ACID, Peroxiredoxin
Authors:Himiyama, T, Nakamura, T.
Deposit date:2019-08-22
Release date:2020-07-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Disassembly of the ring-type decameric structure of peroxiredoxin from Aeropyrum pernix K1 by amino acid mutation.
Protein Sci., 29, 2020
6KRK
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BU of 6krk by Molmil
Peroxiredoxin from Aeropyrum pernix K1 (ApPrx) 0Cys mutant
Descriptor: CITRIC ACID, Peroxiredoxin
Authors:Himiyama, T, Nakamura, T.
Deposit date:2019-08-22
Release date:2020-07-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Disassembly of the ring-type decameric structure of peroxiredoxin from Aeropyrum pernix K1 by amino acid mutation.
Protein Sci., 29, 2020
6KRR
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BU of 6krr by Molmil
Peroxiredoxin from Aeropyrum pernix K1 (ApPrx) 0Cys W210A mutant
Descriptor: Peroxiredoxin
Authors:Himiyama, T, Nakamura, T.
Deposit date:2019-08-22
Release date:2020-07-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Disassembly of the ring-type decameric structure of peroxiredoxin from Aeropyrum pernix K1 by amino acid mutation.
Protein Sci., 29, 2020
6KRM
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BU of 6krm by Molmil
Peroxiredoxin from Aeropyrum pernix K1 (ApPrx) 0Cys F46A mutant
Descriptor: CITRIC ACID, Peroxiredoxin
Authors:Himiyama, T, Nakamura, T.
Deposit date:2019-08-22
Release date:2020-07-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Disassembly of the ring-type decameric structure of peroxiredoxin from Aeropyrum pernix K1 by amino acid mutation.
Protein Sci., 29, 2020
6KRS
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BU of 6krs by Molmil
Peroxiredoxin from Aeropyrum pernix K1 (ApPrx) 0Cys W211A mutant
Descriptor: CITRIC ACID, Peroxiredoxin
Authors:Himiyama, T, Nakamura, T.
Deposit date:2019-08-22
Release date:2020-07-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Disassembly of the ring-type decameric structure of peroxiredoxin from Aeropyrum pernix K1 by amino acid mutation.
Protein Sci., 29, 2020

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