1TG6
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CRYSTALLOGRAPHY AND MUTAGENESIS POINT TO AN ESSENTIAL ROLE FOR THE N-TERMINUS OF HUMAN MITOCHONDRIAL CLPP
Descriptor:Putative ATP-dependent Clp protease proteolytic subunit, 1,4-DIETHYLENE DIOXIDE, 1,2-ETHANEDIOL, ...
Authors:Kang, S.G., Maurizi, M.R., Thompson, M., Mueser, T., Ahvazi, B.
Deposit date:2004-05-28
Release date:2005-03-22
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP
J.Struct.Biol., 148, 2004
1TYF
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THE STRUCTURE OF CLPP AT 2.3 ANGSTROM RESOLUTION SUGGESTS A MODEL FOR ATP-DEPENDENT PROTEOLYSIS
Descriptor:CLP PEPTIDASE
Authors:Wang, J., Hartling, J.A., Flanagan, J.M.
Deposit date:1997-10-13
Release date:1998-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structure of ClpP at 2.3 A resolution suggests a model for ATP-dependent proteolysis.
Cell(Cambridge,Mass.), 91, 1997
1Y7O
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THE STRUCTURE OF STREPTOCOCCUS PNEUMONIAE A153P CLPP
Descriptor:ATP-dependent Clp protease proteolytic subunit, CALCIUM ION
Authors:Kimber, M.S., Gribun, A., Ching, R., Sprangers, R., Fiebig, K.M., Houry, W.A.
Deposit date:2004-12-09
Release date:2005-02-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:The ClpP double ring tetradecameric protease exhibits plastic ring-ring interactions, and the N termini of its subunits form flexible loops that are essential for ClpXP and ClpAP complex formation.
J.Biol.Chem., 280, 2005
1YG6
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CLPP
Descriptor:ATP-dependent Clp protease proteolytic subunit, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Bewley, M.C., Graziano, V., Griffin, K., Flanagan, J.M.
Deposit date:2005-01-04
Release date:2006-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The asymmetry in the mature amino-terminus of ClpP facilitates a local symmetry match in ClpAP and ClpXP complexes.
J.Struct.Biol., 153, 2006
1YG8
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THE STRUCTURE OF A V6A VARIANT OF CLPP.
Descriptor:ATP-dependent Clp protease proteolytic subunit
Authors:Bewley, M.C., Graziano, V., Griffin, K., Flanagan, J.M.
Deposit date:2005-01-04
Release date:2006-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The asymmetry in the mature amino-terminus of ClpP facilitates a local symmetry match in ClpAP and ClpXP complexes.
J.Struct.Biol., 153, 2006
2C8T
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THE 3.0 A RESOLUTION STRUCTURE OF CASEINOLYTIC CLP PROTEASE 1 FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1
Authors:Ingvarsson, H., Hogbom, M., Jones, T.A., Unge, T.
Deposit date:2005-12-07
Release date:2007-02-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Insights Into the Inter-Ring Plasticity of Caseinolytic Proteases from the X-Ray Structure of Mycobacterium Tuberculosis Clpp1.
Acta Crystallogr.,Sect.D, 63, 2007
2CBY
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CRYSTAL STRUCTURE OF THE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 (CLPP1) FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1
Authors:Mate, M.J., Portnoi, D., Alzari, P.M., Ortiz-Lombardia, M.
Deposit date:2006-01-10
Release date:2006-01-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Insights Into the Inter-Ring Plasticity of Caseinolytic Proteases from the X-Ray Structure of Mycobacterium Tuberculosis Clpp1.
Acta Crystallogr.,Sect.D, 63, 2007
2CE3
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CRYSTAL STRUCTURE OF THE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 (CLPP1) FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1
Authors:Segelke, B., Kim, C.Y., Ortiz-Lombardia, M., Alzari, P.M., Lekin, T.
Deposit date:2006-02-03
Release date:2006-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Insights Into the Inter-Ring Plasticity of Caseinolytic Proteases from the X-Ray Structure of Mycobacterium Tuberculosis Clpp1.
Acta Crystallogr.,Sect.D, 63, 2007
2F6I
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CRYSTAL STRUCTURE OF THE CLPP PROTEASE CATALYTIC DOMAIN FROM PLASMODIUM FALCIPARUM
Descriptor:ATP-dependent CLP protease, putative
Authors:Mulichak, A., Loppnau, P., Bray, J., Amani, M., Vedadi, M., Wasney, G., Finerty, P., Sundstrom, M., Weigelt, J., Edwards, A., Arrowsmith, C., Hui, R., Plotnikova, O., Structural Genomics Consortium (SGC)
Deposit date:2005-11-29
Release date:2005-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The Clp chaperones and proteases of the human malaria parasite Plasmodium falciparum.
J.Mol.Biol., 404, 2010
2FZS
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CRYSTAL STRUCTURE OF E. COLI CLPP WITH A PEPTIDE CHLOROMETHYL KETONE COVALENTLY BOUND AT THE ACTIVE SITE
Descriptor:ATP-dependent Clp protease proteolytic subunit, N~2~-[(BENZYLOXY)CARBONYL]-N-[(1S,2S)-2-HYDROXY-1-(4-HYDROXYBENZYL)PROPYL]-L-LEUCINAMIDE, TRIETHYLENE GLYCOL, ...
Authors:Szyk, A., Maurizi, M.R.
Deposit date:2006-02-10
Release date:2006-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure at 1.9A of E. coli ClpP with a peptide covalently bound at the active site.
J.Struct.Biol., 156, 2006
2ZL0
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CRYSTAL STRUCTURE OF H.PYLORI CLPP
Descriptor:ATP-dependent Clp protease proteolytic subunit
Authors:Kim, D.Y., Kim, K.K.
Deposit date:2008-04-02
Release date:2008-04-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The structural basis for the activation and peptide recognition of bacterial ClpP
J.Mol.Biol., 379, 2008
2ZL2
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CRYSTAL STRUCTURE OF H.PYLORI CLPP IN COMPLEX WITH THE PEPTIDE NVLGFTQ
Descriptor:ATP-dependent Clp protease proteolytic subunit, A peptide substrate-NVLGFTQ, A peptide substrate-NVLGFTQ for Chain R and S
Authors:Kim, D.Y., Kim, K.K.
Deposit date:2008-04-02
Release date:2008-04-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structural basis for the activation and peptide recognition of bacterial ClpP
J.Mol.Biol., 379, 2008
2ZL3
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CRYSTAL STRUCTURE OF H.PYLORI CLPP S99A
Descriptor:ATP-dependent Clp protease proteolytic subunit
Authors:Kim, D.Y., Kim, K.K.
Deposit date:2008-04-02
Release date:2008-04-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:The structural basis for the activation and peptide recognition of bacterial ClpP
J.Mol.Biol., 379, 2008
2ZL4
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CRYSTAL STRUCTURE OF H.PYLORI CLPP S99A IN COMPLEX WITH THE PEPTIDE AAAA
Descriptor:ATP-dependent Clp protease proteolytic subunit, Peptide substrate AAAA
Authors:Kim, D.Y., Kim, K.K.
Deposit date:2008-04-02
Release date:2008-04-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structural basis for the activation and peptide recognition of bacterial ClpP
J.Mol.Biol., 379, 2008
3HLN
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CRYSTAL STRUCTURE OF CLPP A153C MUTANT WITH INTER-HEPTAMER DISULFIDE BONDS
Descriptor:ATP-dependent Clp protease proteolytic subunit, CALCIUM ION
Authors:Kimber, M.S., Yu, A.Y.H., Borg, M., Chan, H.S., Houry, W.A.
Deposit date:2009-05-27
Release date:2010-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural and Theoretical Studies Indicate that the Cylindrical Protease ClpP Samples Extended and Compact Conformations.
Structure, 18, 2010
3KTG
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STRUCTURE OF CLPP FROM BACILLUS SUBTILIS IN MONOCLINIC CRYSTAL FORM
Descriptor:ATP-dependent Clp protease proteolytic subunit
Authors:Lee, B.-G., Brotz-Oesterhelt, H., Song, H.K.
Deposit date:2009-11-25
Release date:2010-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism
Nat.Struct.Mol.Biol., 17, 2010
3KTH
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STRUCTURE OF CLPP FROM BACILLUS SUBTILIS IN ORTHOROMBIC CRYSTAL FORM
Descriptor:ATP-dependent Clp protease proteolytic subunit
Authors:Lee, B.-G., Brotz-Oesterhelt, H., Song, H.K.
Deposit date:2009-11-25
Release date:2010-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism
Nat.Struct.Mol.Biol., 17, 2010
3KTI
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STRUCTURE OF CLPP IN COMPLEX WITH ADEP1
Descriptor:ATP-dependent Clp protease proteolytic subunit, Acyldepsipeptide 1, DIMETHYL SULFOXIDE, ...
Authors:Lee, B.-G., Brotz-Oesterhelt, H., Song, H.K.
Deposit date:2009-11-25
Release date:2010-03-23
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism
Nat.Struct.Mol.Biol., 17, 2010
3KTJ
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STRUCTURE OF CLPP IN COMPLEX WITH ADEP2 IN MONOCLINIC CRYSTAL FORM
Descriptor:ATP-dependent Clp protease proteolytic subunit, Acyldepsipeptide 2, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID
Authors:Lee, B.-G., Brotz-Oesterhelt, H., Song, H.K.
Deposit date:2009-11-25
Release date:2010-03-23
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism
Nat.Struct.Mol.Biol., 17, 2010
3KTK
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STRUCTURE OF CLPP IN COMPLEX WITH ADEP2 IN TRICLINIC CRYSTAL FORM
Descriptor:ATP-dependent Clp protease proteolytic subunit, Acyldepsipeptide 2
Authors:Lee, B.-G., Brotz-Oesterhelt, H., Song, H.K.
Deposit date:2009-11-25
Release date:2010-03-23
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism
Nat.Struct.Mol.Biol., 17, 2010
3MT6
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STRUCTURE OF CLPP FROM ESCHERICHIA COLI IN COMPLEX WITH ADEP1
Descriptor:ATP-dependent Clp protease proteolytic subunit, ACYLDEPSIPEPTIDE 1, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Chung, Y.S.
Deposit date:2010-04-30
Release date:2010-11-03
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Acyldepsipeptide antibiotics induce the formation of a structured axial channel in ClpP: A model for the ClpX/ClpA-bound state of ClpP.
Chem.Biol., 17, 2010
3P2L
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CRYSTAL STRUCTURE OF ATP-DEPENDENT CLP PROTEASE SUBUNIT P FROM FRANCISELLA TULARENSIS
Descriptor:ATP-dependent Clp protease proteolytic subunit, MAGNESIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Kim, Y., Zhou, M., Gu, M., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2010-10-02
Release date:2010-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.295 Å)
Cite:Crystal Structure of ATP-dependent Clp protease subunit P from Francisella tularensis
To be Published
3Q7H
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STRUCTURE OF THE CLPP SUBUNIT OF THE ATP-DEPENDENT CLP PROTEASE FROM COXIELLA BURNETII
Descriptor:ATP-dependent Clp protease proteolytic subunit, DI(HYDROXYETHYL)ETHER, CALCIUM ION
Authors:Anderson, S.M., Wawrzak, Z., Gordon, E., Hasseman, J., Anderson, W.F., Savchenko, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-01-04
Release date:2011-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the ClpP subunit of the ATP-dependent Clp Protease from Coxiella burnetii
To be Published
3QWD
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CRYSTAL STRUCTURE OF CLPP FROM STAPHYLOCOCCUS AUREUS
Descriptor:ATP-dependent Clp protease proteolytic subunit, CHLORIDE ION
Authors:Geiger, S.R., Boettcher, T., Sieber, S.A., Cramer, P.
Deposit date:2011-02-28
Release date:2011-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Conformational Switch Underlies ClpP Protease Function.
Angew.Chem.Int.Ed.Engl., 50, 2011
3ST9
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CRYSTAL STRUCTURE OF CLPP IN HEPTAMERIC FORM FROM STAPHYLOCOCCUS AUREUS
Descriptor:ATP-dependent Clp protease proteolytic subunit, SULFATE ION, CALCIUM ION, ...
Authors:Zhang, J., Ye, F., Lan, L., Jiang, H., Luo, C., Yang, C.-G.
Deposit date:2011-07-09
Release date:2011-09-07
Last modified:2012-01-25
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Structural switching of Staphylococcus aureus Clp protease: a key to understanding protease dynamics
J.Biol.Chem., 286, 2011
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