2YC1
 
 | | Crystal structure of the human derived single chain antibody fragment (scFv) 9004G in complex with Cn2 toxin from the scorpion Centruroides noxius Hoffmann | | Descriptor: | BETA-MAMMAL TOXIN CN2, GLYCEROL, SINGLE CHAIN ANTIBODY FRAGMENT 9004G | | Authors: | Canul-Tec, J.C, Riano-Umbarila, L, Rudino-Pinera, E, Becerril, B, Possani, L.D, Torres-Larios, A. | | Deposit date: | 2011-03-10 | | Release date: | 2011-04-13 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural Basis of Neutralization of the Major Toxic Component from the Scorpion Centruroides Noxius Hoffmann by a Human-Derived Single Chain Antibody Fragment.
J.Biol.Chem., 286, 2011
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4V1D
 | | Ternary complex among two human derived single chain antibody fragments and Cn2 toxin from scorpion Centruroides noxius. | | Descriptor: | BETA-MAMMAL TOXIN CN2, SINGLE CHAIN ANTIBODY FRAGMENT LR, HEAVY CHAIN, ... | | Authors: | Riano-Umbarila, L, Serrano-Posada, H, Rojas-Trejo, S, Rudino-Pinera, E, Becerril, B. | | Deposit date: | 2014-09-25 | | Release date: | 2015-10-07 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Optimal Neutralization of Centruroides Noxius Venom is Understood Through a Structural Complex between Two Antibody Fragments and the Cn2 Toxin.
J.Biol.Chem., 291, 2016
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8BO0
 | | Solution structure of Lqq4 toxin from Leiurus quinquestriatus quinquestriatus | | Descriptor: | Alpha-toxin Lqq4 | | Authors: | Mineev, K.S, Motov, V.V, Vassilevski, A.A, Chernykh, M.A, Kuzmenkov, A.I. | | Deposit date: | 2022-11-14 | | Release date: | 2023-09-20 | | Last modified: | 2023-10-04 | | Method: | SOLUTION NMR | | Cite: | A scorpion toxin affecting sodium channels shows double cis-trans isomerism.
Febs Lett., 597, 2023
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4KYP
 | | Beta-Scorpion Toxin folded in the periplasm of E.coli | | Descriptor: | Beta-insect excitatory toxin Bj-xtrIT, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL | | Authors: | O'Reilly, A.O, Cole, A.R, Lopes, J.L, Lampert, A, Wallace, B.A. | | Deposit date: | 2013-05-29 | | Release date: | 2014-02-12 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Chaperone-mediated native folding of a beta-scorpion toxin in the periplasm of Escherichia coli.
Biochim.Biophys.Acta, 1840, 2014
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6VXW
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4AEI
 | | Crystal structure of the AaHII-Fab4C1 complex | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ALPHA-MAMMAL TOXIN AAH2, CHLORIDE ION, ... | | Authors: | Fabrichny, I.P, Mondielli, G, Conrod, S, Martin-Eauclaire, M.F, Bourne, Y, Marchot, P. | | Deposit date: | 2012-01-10 | | Release date: | 2012-03-07 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural Insights Into Antibody Sequestering and Neutralizing of Na+-Channel & [Alpha]-Type Modulator from Old-World Scorpion Venom
J.Biol.Chem., 287, 2012
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5CY0
 | | Total Chemical Synthesis, Covalent Structure Verification, and X-ray Structure of Bioactive Ts3 Toxin by Racemic Protein Crystallography | | Descriptor: | GLYCEROL, Ts3 Toxin | | Authors: | Dang, B, Kubota, T, Mandal, K, Correa, A.M, Bezanilla, F, Kent, S.B. | | Deposit date: | 2015-07-29 | | Release date: | 2016-06-01 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Elucidation of the Covalent and Tertiary Structures of Biologically Active Ts3 Toxin.
Angew.Chem.Int.Ed.Engl., 55, 2016
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6THI
 | | Solution structure of MeuNaTxalpha-1 toxin from Mesobuthus Eupeus | | Descriptor: | Sodium channel neurotoxin MeuNaTxalpha-1 | | Authors: | Mineev, K.S, Kuzmenkov, A.I, Khusainov, G.A, Arseniev, A.S, Vassilevski, A.A. | | Deposit date: | 2019-11-20 | | Release date: | 2020-12-02 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structure of MeuNaTx alpha-1 toxin from scorpion venom highlights the importance of the nest motif.
Proteins, 2021
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5MOU
 | | NMR spatial structure of scorpion alpha-like toxin BeM9 | | Descriptor: | Alpha-mammal toxin BeM9 | | Authors: | Mineev, K.S, Kuldushev, N.A, Berkut, A.A, Grishin, E.V, Vassilevski, A.A, Arseniev, A.S. | | Deposit date: | 2016-12-14 | | Release date: | 2018-01-17 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Refined structure of BeM9 reveals arginine hand, an overlooked structural motif in scorpion toxins affecting sodium channels.
Proteins, 86, 2018
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4HHF
 | | Crystal Structure of chemically synthesized scorpion alpha-toxin OD1 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha-toxin OD1 | | Authors: | Wang, C.I.A, Lewis, R.J, Alewood, P.F, Durek, T. | | Deposit date: | 2012-10-09 | | Release date: | 2013-04-24 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Chemical engineering and structural and pharmacological characterization of the alpha-scorpion toxin OD1.
Acs Chem.Biol., 8, 2013
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2E0H
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2I61
 | | Depressant anti-insect neurotoxin, LqhIT2 from Leiurus quinquestriatus hebraeus | | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, CARBON DIOXIDE, ... | | Authors: | Frolow, F, Gurevitz, M, Karbat, I, Turkov, M, Gordon, D. | | Deposit date: | 2006-08-27 | | Release date: | 2006-12-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | X-ray Structure and Mutagenesis of the Scorpion Depressant Toxin LqhIT2 Reveals Key Determinants Crucial for Activity and Anti-Insect Selectivity.
J.Mol.Biol., 366, 2007
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2SN3
 | | STRUCTURE OF SCORPION TOXIN VARIANT-3 AT 1.2 ANGSTROMS RESOLUTION | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, SCORPION NEUROTOXIN (VARIANT 3) | | Authors: | Zhao, B, Carson, M, Ealick, S.E, Bugg, C.E. | | Deposit date: | 1992-02-20 | | Release date: | 1994-01-31 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Structure of scorpion toxin variant-3 at 1.2 A resolution.
J.Mol.Biol., 227, 1992
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2YBR
 | | Crystal structure of the human derived single chain antibody fragment (scFv) 9004G in complex with Cn2 toxin from the scorpion Centruroides noxius Hoffmann | | Descriptor: | BETA-MAMMAL TOXIN CN2, SINGLE CHAIN ANTIBODY FRAGMENT 9004G | | Authors: | Canul-Tec, J.C, Riano-Umbarila, L, Rudino-Pinera, E, Becerril, B, Possani, L.D, Torres-Larios, A. | | Deposit date: | 2011-03-09 | | Release date: | 2011-04-13 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structural Basis of Neutralization of the Major Toxic Component from the Scorpion Centruroides Noxius Hoffmann by a Human-Derived Single Chain Antibody Fragment
J.Biol.Chem., 286, 2011
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2YEO
 | | A39L mutation of scorpion toxin lqh-alpha-it | | Descriptor: | 1,2-ETHANEDIOL, ALPHA-INSECT TOXIN LQHAIT, CHLORIDE ION, ... | | Authors: | Frolow, F, Kahn, R, Gurevitz, M. | | Deposit date: | 2011-03-28 | | Release date: | 2011-04-13 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.08 Å) | | Cite: | Crystal Structures of Scorpion Alpha-Toxinsmutants Reveal Conformational Constraints that Dictate Preference for Mammalian Brain Voltage-Gated Na- Channels
To be Published
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1I6F
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1I6G
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1JZB
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1JZA
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1JXC
 | | Minimized NMR structure of ATT, an Arabidopsis trypsin/chymotrypsin inhibitor | | Descriptor: | Putative trypsin inhibitor ATTI-2 | | Authors: | Zhao, Q, Chae, Y.K, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2001-09-06 | | Release date: | 2003-01-07 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | NMR Solution Structure of ATTp, an Arabidopsis thaliana Trypsin Inhibitor
Biochemistry, 41, 2002
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1KV0
 | | Cis/trans Isomerization of Non-prolyl Peptide Bond Observed in Crystal Structure of an Scorpion Toxin | | Descriptor: | Alpha-like toxin BmK-M7 | | Authors: | Guan, R.J, He, X.L, Wang, M, Xiang, Y, Wang, D.C. | | Deposit date: | 2002-01-23 | | Release date: | 2003-09-16 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structural mechanism governing cis and trans isomeric states and an intramolecular switch for cis/trans isomerization of a non-proline peptide bond observed in crystal structures of scorpion toxins.
J.Mol.Biol., 341, 2004
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2KBJ
 | | solution structure of BmKalphaTx11 (minor conformation) | | Descriptor: | Toxin Bmka2 | | Authors: | Zhu, J, Wu, H. | | Deposit date: | 2008-11-28 | | Release date: | 2009-12-08 | | Last modified: | 2022-03-16 | | Method: | SOLUTION NMR | | Cite: | Solution structure of BmKalphaTx11, a toxin from the venom of the Chinese scorpion Buthus martensii Karsch
Biochem.Biophys.Res.Commun., 391, 2010
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2KJA
 | | Chemical shift assignments, constraints, and coordinates for CN5 scorpion toxin | | Descriptor: | Beta-toxin Cn5 | | Authors: | Prochnicka-Chalufour, A, Corzo, G, Garcia, B.I, Possani, L.D, Delepierre, M. | | Deposit date: | 2009-05-26 | | Release date: | 2009-10-06 | | Last modified: | 2022-03-16 | | Method: | SOLUTION NMR | | Cite: | Solution structure of Cn5, a crustacean toxin found in the venom of the scorpions Centruroides noxius and Centruroides suffusus suffusus.
Biochim.Biophys.Acta, 1794, 2009
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2KBK
 | | Solution Structure of BmK-M10 | | Descriptor: | Neurotoxin BmK-M10 | | Authors: | Zhu, J, Wu, H. | | Deposit date: | 2008-11-28 | | Release date: | 2009-12-22 | | Last modified: | 2019-12-11 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of BmK-M10
To be Published
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2KBH
 | | solution structure of BmKalphaTx11 (major conformation) | | Descriptor: | Toxin Bmka2 | | Authors: | Zhu, J, Wu, H. | | Deposit date: | 2008-11-28 | | Release date: | 2009-12-08 | | Last modified: | 2019-12-11 | | Method: | SOLUTION NMR | | Cite: | Solution structure of BmKalphaTx11, a toxin from the venom of the Chinese scorpion Buthus martensii Karsch
Biochem.Biophys.Res.Commun., 391, 2010
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