4CC9
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CRYSTAL STRUCTURE OF HUMAN SAMHD1 (AMINO ACID RESIDUES 582-626) BOUND TO VPX ISOLATED FROM SOOTY MANGABEY AND HUMAN DCAF1 (AMINO ACID RESIDUES 1058-1396)
Descriptor:PROTEIN VPRBP, PROTEIN VPX, DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1 (E.C.3.1.5.-)
Authors:Schwefel, D., Groom, H.C.T., Boucherit, V.C., Christodoulou, E., Walker, P.A., Stoye, J.P., Bishop, K.N., Taylor, I.A.
Deposit date:2013-10-19
Release date:2013-12-11
Last modified:2014-01-08
Method:X-RAY DIFFRACTION (2.473 Å)
Cite:Structural Basis of Lentiviral Subversion of a Cellular Protein Degradation Pathway.
Nature, 505, 2014
5AJA
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CRYSTAL STRUCTURE OF MANDRILL SAMHD1 (AMINO ACID RESIDUES 1-114) BOUND TO VPX ISOLATED FROM MANDRILL AND HUMAN DCAF1 (AMINO ACID RESIDUES 1058-1396)
Descriptor:PROTEIN VPRBP (E.C.2.7.11.1), VPX PROTEIN, SAM DOMAIN AND HD DOMAIN-CONTAINING PROTEIN
Authors:Schwefel, D., Boucherit, V.C., Christodoulou, E., Walker, P.A., Stoye, J.P., Bishop, K.N., Taylor, I.A.
Deposit date:2015-02-20
Release date:2015-04-22
Method:X-RAY DIFFRACTION (2.649 Å)
Cite:Molecular Determinants for Recognition of Divergent Samhd1 Proteins by the Lentiviral Accessory Protein Vpx.
Cell Host Microbe., 17, 2015
5JK7
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THE X-RAY STRUCTURE OF THE DDB1-DCAF1-VPR-UNG2 COMPLEX
Descriptor:DNA damage-binding protein 1, Protein VPRBP (E.C.2.7.11.1), Uracil-DNA glycosylase (E.C.3.2.2.27), Protein Vpr
Authors:Calero, G., Ahn, J., Wu, Y.
Deposit date:2016-04-26
Release date:2016-10-05
Last modified:2016-10-19
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:The DDB1-DCAF1-Vpr-UNG2 crystal structure reveals how HIV-1 Vpr steers human UNG2 toward destruction.
Nat.Struct.Mol.Biol., 23, 2016
1ESX
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1H, 15N AND 13C STRUCTURE OF THE HIV-1 REGULATORY PROTEIN VPR : COMPARISON WITH THE N-AND C-TERMINAL DOMAIN STRUCTURE, (1-51)VPR AND (52-96)VPR
Descriptor:VPR PROTEIN
Authors:Wecker, K., Morellet, N., Bouaziz, S., Roques, B.
Deposit date:2000-04-11
Release date:2001-04-11
Last modified:2013-03-27
Method:SOLUTION NMR
Cite:NMR structure of the HIV-1 regulatory protein Vpr in H2O/trifluoroethanol. Comparison with the Vpr N-terminal (1-51) and C-terminal (52-96) domains.
Eur.J.Biochem., 269, 2002
1M8L
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NMR STRUCTURE OF THE HIV-1 REGULATORY PROTEIN VPR
Descriptor:VPR Protein
Authors:Morellet, N., Bouaziz, S., Lenoir, C., Roques, B.P.
Deposit date:2002-07-25
Release date:2003-03-18
Last modified:2009-02-24
Method:SOLUTION NMR
Cite:NMR Structure of the HIV-1 Regulatory Protein Vpr
J.Mol.Biol., 327, 2003
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