6MHX
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STRUCTURE OF HUMAN TRPV3 IN THE PRESENCE OF 2-APB IN C2 SYMMETRY (2)
Descriptor:Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L., Herzik, M.A., Wu, M., Borschel, W.F., Hirschi, M., Song, A., Lander, G.C., Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel
To be Published
6MHW
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STRUCTURE OF HUMAN TRPV3 IN THE PRESENCE OF 2-APB IN C2 SYMMETRY (1)
Descriptor:Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L., Herzik, M.A., Wu, M., Borschel, W.F., Hirschi, M., Song, A., Lander, G.C., Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel
To be Published
6MHV
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STRUCTURE OF HUMAN TRPV3 IN THE PRESENCE OF 2-APB IN C4 SYMMETRY
Descriptor:Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L., Herzik, M.A., Wu, M., Borschel, W.F., Hirschi, M., Song, A., Lander, G.C., Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel
To be Published
6MHS
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STRUCTURE OF THE HUMAN TRPV3 CHANNEL IN A PUTATIVE SENSITIZED CONFORMATION
Descriptor:Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L., Herzik, M.A., Wu, M., Borschel, W.F., Hirschi, M., Song, A., Lander, G.C., Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel
To be Published
6MHO
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STRUCTURE OF THE HUMAN TRPV3 CHANNEL IN THE APO CONFORMATION
Descriptor:Transient receptor potential cation channel subfamily V member 3
Authors:Zubcevic, L., Herzik, M.A., Wu, M., Borschel, W.F., Hirschi, M., Song, A., Lander, G.C., Lee, S.Y.
Deposit date:2018-09-18
Release date:2018-10-03
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Conformational ensemble of the human TRPV3 ion channel
To be Published
6G1K
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ELECTRON CRYO-MICROSCOPY STRUCTURE OF THE CANONICAL TRPC4 ION CHANNEL
Descriptor:Transient receptor potential cation channel subfamily c member 4a, CHOLESTEROL HEMISUCCINATE, (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate
Authors:Vinayagam, D., Mager, T., Apelbaum, A., Bothe, A., Merino, F., Hofnagel, O., Gatsogiannis, C., Raunser, S.
Deposit date:2018-03-21
Release date:2018-05-02
Last modified:2018-08-01
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Electron cryo-microscopy structure of the canonical TRPC4 ion channel.
Elife, 7, 2018
6FOO
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STRUCTURE OF RYANODINE RECEPTOR 1 IN NANODISCS IN THE PRESENCE OF CALCIUM AND ATP
Descriptor:Ryanodine receptor 1, ZINC ION
Authors:Willegems, K., Efremov, R.G.
Deposit date:2018-02-08
Release date:2018-08-08
Last modified:2018-10-10
Method:ELECTRON MICROSCOPY (8.2 Å)
Cite:Influence of Lipid Mimetics on Gating of Ryanodine Receptor.
Structure, 26, 2018
6FG3
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STRUCTURE OF RYANODINE RECEPTOR 1 IN NANODISCS IN THE PRESENCE OF CALCIUM, ATP AND RYANODINE
Descriptor:Ryanodine receptor 1, ZINC ION, CALCIUM ION
Authors:Willegems, K., Efremov, R.G.
Deposit date:2018-01-09
Release date:2018-08-08
Last modified:2018-10-10
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:Influence of Lipid Mimetics on Gating of Ryanodine Receptor.
Structure, 26, 2018
6EBM
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THE VOLTAGE-ACTIVATED KV1.2-2.1 PADDLE CHIMERA CHANNEL IN LIPID NANODISCS, TRANSMEMBRANE DOMAIN OF SUBUNIT ALPHA
Descriptor:Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera
Authors:Matthies, D., Bae, C., Fox, T., Bartesaghi, A., Subramaniam, S., Swartz, K.J.
Deposit date:2018-08-06
Release date:2018-08-22
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs.
Elife, 7, 2018
6EBL
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THE VOLTAGE-ACTIVATED KV1.2-2.1 PADDLE CHIMERA CHANNEL IN LIPID NANODISCS, CYTOSOLIC DOMAIN
Descriptor:Voltage-gated potassium channel subunit beta-2, Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Matthies, D., Bae, C., Fox, T., Bartesaghi, A., Subramaniam, S., Swartz, K.J.
Deposit date:2018-08-06
Release date:2018-08-22
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs.
Elife, 7, 2018
6EBK
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THE VOLTAGE-ACTIVATED KV1.2-2.1 PADDLE CHIMERA CHANNEL IN LIPID NANODISCS
Descriptor:Voltage-gated potassium channel subunit beta-2, Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Matthies, D., Bae, C., Fox, T., Bartesaghi, A., Subramaniam, S., Swartz, K.J.
Deposit date:2018-08-06
Release date:2018-08-22
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs.
Elife, 7, 2018
6E2G
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CRYO-EM STRUCTURE OF RAT TRPV6 IN COMPLEX WITH CALMODULIN
Descriptor:Transient receptor potential cation channel subfamily V member 6, Calmodulin-1, CALCIUM ION
Authors:Singh, A.K., McGoldrick, L.L., Sobolevsky, A.I.
Deposit date:2018-07-11
Release date:2018-08-22
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Mechanism of calmodulin inactivation of the calcium-selective TRP channel TRPV6.
Sci Adv, 4, 2018
6E2F
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CRYO-EM STRUCTURE OF HUMAN TRPV6 IN COMPLEX WITH CALMODULIN
Descriptor:Transient receptor potential cation channel subfamily V member 6, Calmodulin-1, CALCIUM ION
Authors:Singh, A.K., McGoldrick, L.L., Sobolevsky, A.I.
Deposit date:2018-07-11
Release date:2018-08-22
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Mechanism of calmodulin inactivation of the calcium-selective TRP channel TRPV6.
Sci Adv, 4, 2018
6E1P
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STRUCTURE OF ATTPC1(DDE) IN STATE 2
Descriptor:Two pore calcium channel protein 1, CALCIUM ION, PALMITIC ACID
Authors:Kintzer, A.F., Green, E.M., Cheng, Y., Stroud, R.M.
Deposit date:2018-07-10
Release date:2018-09-19
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6E1N
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STRUCTURE OF ATTPC1(DDE) IN STATE 1
Descriptor:Two pore calcium channel protein 1, CALCIUM ION, PALMITIC ACID, ...
Authors:Kintzer, A.F., Green, E.M., Cheng, Y., Stroud, R.M.
Deposit date:2018-07-10
Release date:2018-09-19
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6E1M
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STRUCTURE OF ATTPC1(DDE) RECONSTITUTED IN SAPOSIN A
Descriptor:Two pore calcium channel protein 1, CALCIUM ION, PALMITIC ACID, ...
Authors:Kintzer, A.F., Green, E.M., Cheng, Y., Stroud, R.M.
Deposit date:2018-07-10
Release date:2018-09-19
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6E1K
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STRUCTURE OF ATTPC1(DDE) RECONSTITUTED IN SAPOSIN A WITH CAT06 FAB
Descriptor:Two pore calcium channel protein 1, cat06 light chain, cat06 heavy chain, ...
Authors:Kintzer, A.F., Green, E.M., Cheng, Y., Stroud, R.M.
Deposit date:2018-07-10
Release date:2018-09-19
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DVZ
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CRYO-EM STRUCTURE OF MOUSE TRPV3-Y564A IN COMPLEX WITH 2-AMINOETHOXYDIPHENYL BORATE (2-APB)
Descriptor:Transient receptor potential cation channel subfamily V member 3, 2-aminoethyl diphenylborinate
Authors:Singh, A.K., McGoldrick, L.L., Sobolevsky, A.I.
Deposit date:2018-06-25
Release date:2018-09-05
Last modified:2018-09-19
Method:ELECTRON MICROSCOPY (4.24 Å)
Cite:Structure and gating mechanism of the transient receptor potential channel TRPV3.
Nat. Struct. Mol. Biol., 25, 2018
6DVY
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CRYO-EM STRUCTURE OF MOUSE TRPV3 IN COMPLEX WITH 2-AMINOETHOXYDIPHENYL BORATE (2-APB)
Descriptor:Transient receptor potential cation channel subfamily V member 3, 2-aminoethyl diphenylborinate
Authors:Singh, A.K., McGoldrick, L.L., Sobolevsky, A.I.
Deposit date:2018-06-25
Release date:2018-09-05
Last modified:2018-09-19
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure and gating mechanism of the transient receptor potential channel TRPV3.
Nat. Struct. Mol. Biol., 25, 2018
6DVW
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CRYO-EM STRUCTURE OF MOUSE TRPV3
Descriptor:Transient receptor potential cation channel subfamily V member 3
Authors:Singh, A.K., McGoldrick, L.L., Sobolevsky, A.I.
Deposit date:2018-06-25
Release date:2018-09-05
Last modified:2018-09-19
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structure and gating mechanism of the transient receptor potential channel TRPV3.
Nat. Struct. Mol. Biol., 25, 2018
6DRC
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HIGH IP3 CA2+ HUMAN TYPE 3 1,4,5-INOSITOL TRISPHOSPHATE RECEPTOR
Descriptor:Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ...
Authors:Hite, R.K., Paknejad, N.
Deposit date:2018-06-11
Release date:2018-08-01
Last modified:2018-08-15
Method:ELECTRON MICROSCOPY (3.92 Å)
Cite:Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3.
Nat. Struct. Mol. Biol., 25, 2018
6DRA
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LOW IP3 CA2+ HUMAN TYPE 3 1,4,5-INOSITOL TRISPHOSPHATE RECEPTOR
Descriptor:Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION, CALCIUM ION
Authors:Hite, R.K., Paknejad, N.
Deposit date:2018-06-11
Release date:2018-08-01
Last modified:2018-08-15
Method:ELECTRON MICROSCOPY (3.96 Å)
Cite:Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3.
Nat. Struct. Mol. Biol., 25, 2018
6DR2
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CA2+-BOUND HUMAN TYPE 3 1,4,5-INOSITOL TRISPHOSPHATE RECEPTOR
Descriptor:Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION, CALCIUM ION
Authors:Hite, R.K., Paknejad, N.
Deposit date:2018-06-11
Release date:2018-07-18
Last modified:2018-08-15
Method:ELECTRON MICROSCOPY (4.33 Å)
Cite:Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3.
Nat. Struct. Mol. Biol., 25, 2018
6DR0
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CLASS 5 IP3-BOUND HUMAN TYPE 3 1,4,5-INOSITOL TRISPHOSPHATE RECEPTOR
Descriptor:Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE
Authors:Hite, R.K., Paknejad, N.
Deposit date:2018-06-11
Release date:2018-08-01
Last modified:2018-08-15
Method:ELECTRON MICROSCOPY (4.47 Å)
Cite:Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3.
Nat. Struct. Mol. Biol., 25, 2018
6DQZ
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CLASS 4 IP3-BOUND HUMAN TYPE 3 1,4,5-INOSITOL TRISPHOSPHATE RECEPTOR
Descriptor:Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE
Authors:Hite, R.K., Paknejad, N.
Deposit date:2018-06-11
Release date:2018-08-01
Last modified:2018-08-15
Method:ELECTRON MICROSCOPY (6.01 Å)
Cite:Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3.
Nat. Struct. Mol. Biol., 25, 2018
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