PDB: 101 resultsInfo pagesStatus searchChemie searchBIRD

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8S4G	Cryo-EM structure of the Anaphase-promoting complex/cyclosome (APC/C) bound to co-activator Cdh1 at 3.2 Angstrom resolution Descriptor: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... Authors: Hoefler, A, Yu, J, Chang, L, Zhang, Z, Yang, J, Boland, A, Barford, D. Deposit date: 2024-02-21 Release date: 2024-03-13 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: New structural features of the APC/C revealed by high resolution cryo-EM structures of apo-APC/C and the APC/C-CDH1-EMI1 complex To Be Published
8FFW	Cryo-EM structure of the GR-Hsp90-FKBP51 complex Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DEXAMETHASONE, Glucocorticoid receptor, ... Authors: Noddings, C.M, Agard, D.A. Deposit date: 2022-12-10 Release date: 2023-11-01 Last modified: 2023-12-20 Method: ELECTRON MICROSCOPY (3.23 Å) Cite: Cryo-EM reveals how Hsp90 and FKBP immunophilins co-regulate the glucocorticoid receptor. Nat.Struct.Mol.Biol., 30, 2023
8FFV	Cryo-EM structure of the GR-Hsp90-FKBP52 complex Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DEXAMETHASONE, Glucocorticoid receptor, ... Authors: Noddings, C.M, Agard, D.A. Deposit date: 2022-12-10 Release date: 2023-11-01 Last modified: 2023-12-20 Method: ELECTRON MICROSCOPY (3.01 Å) Cite: Cryo-EM reveals how Hsp90 and FKBP immunophilins co-regulate the glucocorticoid receptor. Nat.Struct.Mol.Biol., 30, 2023
8TAU	APC/C-CDH1-UBE2C-UBE2S-Ubiquitin-CyclinB Descriptor: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... Authors: Bodrug, T, Welsh, K.A, Bolhuis, D.L, Paulakonis, E, Martinez-Chacin, R.C, Liu, B, Pinkin, N, Bonacci, T, Cui, L, Xu, P, Roscow, O, Amann, S.J, Grishkovskaya, I, Emanuele, M.J, Harrison, J.S, Steimel, J.P, Hahn, K.M, Zhang, W, Zhong, E, Haselbach, D, Brown, N.G. Deposit date: 2023-06-27 Release date: 2023-09-27 Last modified: 2023-12-13 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C). Nat.Struct.Mol.Biol., 30, 2023
8TAR	APC/C-CDH1-UBE2C-Ubiquitin-CyclinB-NTD Descriptor: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... Authors: Bodrug, T, Welsh, K.A, Bolhuis, D.L, Paulakonis, E, Martinez-Chacin, R.C, Liu, B, Pinkin, N, Bonacci, T, Cui, L, Xu, P, Roscow, O, Amann, S.J, Grishkovskaya, I, Emanuele, M.J, Harrison, J.S, Steimel, J.P, Hahn, K.M, Zhang, W, Zhong, E, Haselbach, D, Brown, N.G. Deposit date: 2023-06-27 Release date: 2023-09-27 Last modified: 2023-11-22 Method: ELECTRON MICROSCOPY (4 Å) Cite: Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C). Nat.Struct.Mol.Biol., 30, 2023
8PKP	Cryo-EM structure of the apo Anaphase-promoting complex/cyclosome (APC/C) at 3.2 Angstrom resolution Descriptor: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... Authors: Hoefler, A, Yu, J, Chang, L, Zhang, Z, Yang, J, Boland, A, Barford, D. Deposit date: 2023-06-27 Release date: 2023-07-19 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: High-resolution structure of the Anaphase-promoting complex (APC/C) bound to co-activator Cdh1 To Be Published
7YEH	Cryo-EM structure of human OGT-OGA complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein O-GlcNAcase, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, ... Authors: Lu, P, Liu, Y, Yu, H, Gao, H. Deposit date: 2022-07-05 Release date: 2023-07-12 Last modified: 2024-01-24 Method: ELECTRON MICROSCOPY (3.92 Å) Cite: Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex. Nat Commun, 14, 2023
7YEA	Human O-GlcNAc transferase Dimer Descriptor: UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit Authors: Gao, H, Lu, P, Liu, Y. Deposit date: 2022-07-05 Release date: 2023-07-12 Last modified: 2024-01-24 Method: ELECTRON MICROSCOPY (3.82 Å) Cite: Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex. Nat Commun, 14, 2023
8GFT	Hsp90 provides platform for CRaf dephosphorylation by PP5 Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, ... Authors: Jaime-Garza, M, Nowotny, C.A, Coutandin, D, Wang, F, Tabios, M, Agard, D.A. Deposit date: 2023-03-08 Release date: 2023-05-03 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Hsp90 provides a platform for kinase dephosphorylation by PP5. Nat Commun, 14, 2023
8GAE	Hsp90 provides platform for CRaf dephosphorylation by PP5 Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, ... Authors: Jaime-Garza, M, Nowotny, C.A, Coutandin, D, Wang, F, Tabios, M, Agard, D.A. Deposit date: 2023-02-22 Release date: 2023-04-26 Last modified: 2023-05-03 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Hsp90 provides a platform for kinase dephosphorylation by PP5. Nat Commun, 14, 2023
8DTF	Cryo-EM structure of the full length Arabidopsis SPY with complete TPRs Descriptor: Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY Authors: Kumar, S, Zhou, Y, Dillard, L, Borgnia, M.J, Bartesaghi, A, Zhou, P. Deposit date: 2022-07-25 Release date: 2023-03-08 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Cryo-EM structure of the full length Arabidopsis SPY with complete TPRs Nat Commun, 2023
8DTH	Cryo-EM structure of Arabidopsis SPY alternative conformation 2 Descriptor: Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY Authors: Kumar, S, Zhou, Y, Dillard, L, Borgnia, M.J, Bartesaghi, A, Zhou, P. Deposit date: 2022-07-25 Release date: 2023-03-08 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Cryo-EM structure of the full length Arabidopsis SPY with complete TPRs Nat Commun, 2023
8DTI	Cryo-EM structure of Arabidopsis SPY in complex with GDP-fucose Descriptor: GUANOSINE-5'-DIPHOSPHATE-BETA-L-FUCOPYRANOSE, Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY Authors: Kumar, S, Zhou, Y, Dillard, L, Borgnia, M.J, Bartesaghi, A, Zhou, P. Deposit date: 2022-07-25 Release date: 2023-03-08 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Cryo-EM structure of the full length Arabidopsis SPY with complete TPRs Nat Commun, 2023
8DTG	Cryo-EM structure of Arabidopsis SPY alternative conformation 1 Descriptor: Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY Authors: Kumar, S, Zhou, Y, Dillard, L, Borgnia, M.J, Bartesaghi, A, Zhou, P. Deposit date: 2022-07-25 Release date: 2023-03-08 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Cryo-EM structure of the full length Arabidopsis SPY with complete TPRs Nat Commun, 2023
7ZR6	CryoEM structure of HSP90-CDC37-BRAF(V600E)-PP5(open) complex Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ... Authors: Oberoi, J, Pearl, L.H. Deposit date: 2022-05-03 Release date: 2022-12-28 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation. Nat Commun, 13, 2022
7ZR5	CryoEM structure of HSP90-CDC37-BRAF(V600E)-PP5(closed) complex Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ... Authors: Oberoi, J, Pearl, L.H. Deposit date: 2022-05-03 Release date: 2022-12-14 Last modified: 2022-12-21 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation. Nat Commun, 13, 2022
7Y4I	Crystal structure of SPINDLY in complex with GDP Descriptor: GUANOSINE-5'-DIPHOSPHATE, Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY Authors: Xu, S.T, Wan, L.H. Deposit date: 2022-06-14 Release date: 2022-12-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Structural insights into mechanism and specificity of the plant protein O-fucosyltransferase SPINDLY. Nat Commun, 13, 2022
8EBF	C-terminal (TPR) domain of LIC11990 from Leptospira interrogans Descriptor: ACETATE ION, Cytoplasmic membrane protein, GLYCEROL Authors: Larrieux, N, Buschiazzo, A. Deposit date: 2022-08-31 Release date: 2022-09-21 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure and function of a novel membrane-associated protein from Leptospira interrogans (gene LIC11990) To Be Published
8A5Y	S. cerevisiae apo unphosphorylated APC/C. Descriptor: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ... Authors: Barford, D, Fernandez-Vazquez, E, Zhang, Z, Yang, J. Deposit date: 2022-06-16 Release date: 2022-08-31 Last modified: 2023-07-26 Method: ELECTRON MICROSCOPY (4.9 Å) Cite: Cryo-EM structure of the S. cerevisiae APC/C-Cdh1 complex and comparison to apo unphosphorylated and phosphorylated states To Be Published
8A61	S. cerevisiae apo phosphorylated APC/C Descriptor: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ... Authors: Barford, D, Fernandez-Vazquez, E, Zhang, Z, Yang, J. Deposit date: 2022-06-16 Release date: 2022-08-31 Method: ELECTRON MICROSCOPY (5.4 Å) Cite: Cryo-EM structure of the S. cerevisiae apo phosphorylated APC/C To Be Published
8A3T	S. cerevisiae APC/C-Cdh1 complex Descriptor: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ... Authors: Barford, D, Vazquez-Fernandez, E, Zhang, Z, Yang, J. Deposit date: 2022-06-09 Release date: 2022-08-31 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Cryo-EM structure of the S. cerevisiae APC/C-Cdh1 complex To Be Published
7QE7	High-resolution structure of the Anaphase-promoting complex/cyclosome (APC/C) bound to co-activator Cdh1 Descriptor: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... Authors: Hoefler, A, Yu, J, Chang, L, Zhang, Z, Yang, J, Boland, A, Barford, D. Deposit date: 2021-12-01 Release date: 2022-01-26 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: High-resolution structure of the Anaphase-promoting complex (APC/C) bound to co-activator Cdh1 To Be Published
7KW7	Atomic cryoEM structure of Hsp90-Hsp70-Hop-GR Descriptor: ADENOSINE-5'-DIPHOSPHATE, Glucocorticoid receptor, Heat shock 70 kDa protein 1A, ... Authors: Wang, R.Y, Noddings, C.M, Kirschke, E, Myasnikov, A, Johnson, J.L, Agard, D.A. Deposit date: 2020-11-30 Release date: 2021-12-08 Last modified: 2022-02-02 Method: ELECTRON MICROSCOPY (3.57 Å) Cite: Structure of Hsp90-Hsp70-Hop-GR reveals the Hsp90 client-loading mechanism. Nature, 601, 2022
7NTF	Cryo-EM structure of unliganded O-GlcNAc transferase Descriptor: Isoform 1 of UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit Authors: Meek, R.W, Blaza, J.N, Davies, G.J. Deposit date: 2021-03-09 Release date: 2021-11-17 Last modified: 2021-11-24 Method: ELECTRON MICROSCOPY (5.32 Å) Cite: Cryo-EM structure provides insights into the dimer arrangement of the O-linked beta-N-acetylglucosamine transferase OGT. Nat Commun, 12, 2021
7AI4	Crystal structure of the KLC1-TPR domain truncated from its nonTPR region ([A1-B6]-Delta-nonTPR fragment) Descriptor: Isoform C of Kinesin light chain 1,Isoform C of Kinesin light chain 1 Authors: Menetrey, J, Llinas, P. Deposit date: 2020-09-26 Release date: 2021-10-06 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.795 Å) Cite: Structural investigations of the dynamics of the TPR domain of kinesin light chain To Be Published

 

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