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1A17
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TETRATRICOPEPTIDE REPEATS OF PROTEIN PHOSPHATASE 5
Descriptor: SERINE/THREONINE PROTEIN PHOSPHATASE 5, SULFATE ION
Authors:Das, A.K, Cohen, P.T.W, Barford, D.
Deposit date:1997-12-23
Release date:1998-04-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The structure of the tetratricopeptide repeats of protein phosphatase 5: implications for TPR-mediated protein-protein interactions.
EMBO J., 17, 1998
1ELR
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BU of 1elr by Molmil
Crystal structure of the TPR2A domain of HOP in complex with the HSP90 peptide MEEVD
Descriptor: HSP90-PEPTIDE MEEVD, NICKEL (II) ION, TPR2A-DOMAIN OF HOP
Authors:Scheufler, C, Brinker, A, Hartl, F.U, Moarefi, I.
Deposit date:2000-03-14
Release date:2000-04-26
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine.
Cell(Cambridge,Mass.), 101, 2000
1KT0
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Structure of the Large FKBP-like Protein, FKBP51, Involved in Steroid Receptor Complexes
Descriptor: 51 KDA FK506-BINDING PROTEIN, SULFATE ION
Authors:Sinars, C.R, Cheung-Flynn, J, Rimerman, R.A, Scammell, J.G, Smith, D.F, Clardy, J.C.
Deposit date:2002-01-14
Release date:2003-02-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the large FK506-binding protein FKBP51, an Hsp90-binding protein and a component of steroid receptor complexes
Proc.Natl.Acad.Sci.USA, 100, 2003
1KT1
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Structure of the Large FKBP-like Protein, FKBP51, Involved in Steroid Receptor Complexes
Descriptor: FK506-binding protein FKBP51, SULFATE ION
Authors:Sinars, C.R, Cheung-Flynn, J, Rimerman, R.A, Scammell, J.G, Smith, D.F, Clardy, J.C.
Deposit date:2002-01-14
Release date:2003-02-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:STRUCTURE OF THE LARGE FK506-BINDING PROTEIN FKBP51, AN HSP90-BINDING PROTEIN AND A COMPONENT OF STEROID RECEPTOR COMPLEXES
Proc.Natl.Acad.Sci.USA, 100, 2003
1P5Q
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Crystal Structure of FKBP52 C-terminal Domain
Descriptor: FK506-binding protein 4, SULFATE ION
Authors:Wu, B, Li, P, Lou, Z, Shu, C, Ding, Y, Shen, B, Rao, Z.
Deposit date:2003-04-28
Release date:2004-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:3D structure of human FK506-binding protein 52: Implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex
Proc.Natl.Acad.Sci.USA, 101, 2004
1QZ2
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Crystal Structure of FKBP52 C-terminal Domain complex with the C-terminal peptide MEEVD of Hsp90
Descriptor: 5-mer peptide from Heat shock protein HSP 90, FK506-binding protein 4
Authors:Wu, B, Li, P, Lou, Z, Liu, Y, Ding, Y, Shu, C, Shen, B, Rao, Z.
Deposit date:2003-09-15
Release date:2004-06-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:3D structure of human FK506-binding protein 52: Implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex.
Proc.Natl.Acad.Sci.USA, 101, 2004
1W3B
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The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Descriptor: CALCIUM ION, UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110
Authors:Jinek, M, Rehwinkel, J, Lazarus, B.D, Izaurralde, E, Hanover, J.A, Conti, E.
Deposit date:2004-07-14
Release date:2004-09-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:The Superhelical Tpr-Repeat Domain of O-Linked Glcnac Transferase Exhibits Structural Similarities to Importin Alpha
Nat.Struct.Mol.Biol., 11, 2004
1WAO
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PP5 structure
Descriptor: MANGANESE (II) ION, SERINE/THREONINE PROTEIN PHOSPHATASE 5
Authors:Barford, D.
Deposit date:2004-10-27
Release date:2005-02-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular Basis for Tpr Domain-Mediated Regulation of Protein Phosphatase 5
Embo J., 24, 2005
2BUG
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BU of 2bug by Molmil
Solution structure of the TPR domain from Protein phosphatase 5 in complex with Hsp90 derived peptide
Descriptor: HSP90, SERINE/THREONINE PROTEIN PHOSPHATASE 5
Authors:Cliff, M.J, Harris, R, Barford, D, Ladbury, J.E, Williams, M.A.
Deposit date:2005-06-13
Release date:2006-03-16
Last modified:2020-01-15
Method:SOLUTION NMR
Cite:Conformational Diversity in the Tpr Domain-Mediated Interaction of Protein Phosphatase 5 with Hsp90.
Structure, 14, 2006
2GW1
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Crystal Structure of the Yeast Tom70
Descriptor: Mitochondrial precursor proteins import receptor
Authors:Wu, Y, Sha, B.
Deposit date:2006-05-03
Release date:2006-06-27
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of yeast mitochondrial outer membrane translocon member Tom70p.
Nat.Struct.Mol.Biol., 13, 2006
3CVQ
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Structure of Peroxisomal Targeting Signal 1 (PTS1) binding domain of Trypanosoma brucei Peroxin 5 (TbPEX5)complexed to PTS1 peptide (7-SKL)
Descriptor: GLYCEROL, PTS1 peptide 7-SKL (Ac-SNRWSKL), Peroxisome targeting signal 1 receptor PEX5
Authors:Sampathkumar, P, Roach, C, Michels, P.A.M, Hol, W.G.J.
Deposit date:2008-04-18
Release date:2008-06-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structural Insights into the recognition of peroxisomal targeting signal 1 by Trypanosoma brucei peroxin 5.
J.Mol.Biol., 381, 2008
3CVP
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Structure of Peroxisomal Targeting Signal 1 (PTS1) binding domain of Trypanosoma brucei Peroxin 5 (TbPEX5)complexed to PTS1 peptide (10-SKL)
Descriptor: 10-SKL PTS1 peptide Ac-GTLSNRASKL, Peroxisome targeting signal 1 receptor PEX5
Authors:Sampathkumar, P, Roach, C, Michels, P.A.M, Hol, W.G.J.
Deposit date:2008-04-18
Release date:2008-06-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insights into the recognition of peroxisomal targeting signal 1 by Trypanosoma brucei peroxin 5.
J.Mol.Biol., 381, 2008
3CV0
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Structure of Peroxisomal Targeting Signal 1 (PTS1) binding domain of Trypanosoma brucei Peroxin 5 (TbPEX5)complexed to T. brucei Phosphoglucoisomerase (PGI) PTS1 peptide
Descriptor: 1,2-ETHANEDIOL, Peroxisome targeting signal 1 receptor PEX5, T. brucei PGI PTS1 peptide Ac-FNELSHL
Authors:Sampathkumar, P, Roach, C, Michels, P.A.M, Hol, W.G.J.
Deposit date:2008-04-17
Release date:2008-06-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insights into the recognition of peroxisomal targeting signal 1 by Trypanosoma brucei peroxin 5.
J.Mol.Biol., 381, 2008
2VYI
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BU of 2vyi by Molmil
Crystal Structure of the TPR domain of Human SGT
Descriptor: SGTA PROTEIN
Authors:Dutta, S, Tan, Y.J.
Deposit date:2008-07-24
Release date:2008-08-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and Functional Characterization of Human Sgt and its Interaction with Vpu of the Human Immunodeficiency Virus Type 1.
Biochemistry, 47, 2008
2KC7
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BU of 2kc7 by Molmil
Solution NMR structure of Bacteroides fragilis protein BF1650. Northeast Structural Genomics Consortium target BfR218
Descriptor: bfr218_protein
Authors:Eletsky, A, Wu, Y, Sukumaran, D, Lee, H, Lee, D.Y, Jiang, M, Foote, E.L, Xiao, R, Nair, R, Everett, J.K, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Prestegard, J.H, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2008-12-17
Release date:2009-01-13
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution NMR structure of Bacteroides fragilis protein BF1650. Northeast Structural Genomics Consortium target BfR218
To be Published
3FWV
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Crystal Structure of a Redesigned TPR Protein, T-MOD(VMY), in Complex with MEEVF Peptide
Descriptor: Heat shock protein HSP 90-beta, Hsc70/Hsp90-organizing protein, NICKEL (II) ION
Authors:Jackrel, M.E, Valverde, R, Regan, L.
Deposit date:2009-01-19
Release date:2009-04-21
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Redesign of a protein-peptide interaction: characterization and applications
Protein Sci., 18, 2009
3ESK
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BU of 3esk by Molmil
Structure of HOP TPR2A domain in complex with the non-cognate Hsc70 peptide ligand
Descriptor: Heat shock cognate 71 kDa protein, NICKEL (II) ION, Stress-induced-phosphoprotein 1
Authors:Kajander, T, Regan, L.
Deposit date:2008-10-06
Release date:2009-07-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Electrostatic interactions of Hsp-organizing protein tetratricopeptide domains with Hsp70 and Hsp90: computational analysis and protein engineering.
J.Biol.Chem., 284, 2009
3FP2
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BU of 3fp2 by Molmil
Crystal structure of Tom71 complexed with Hsp82 C-terminal fragment
Descriptor: ATP-dependent molecular chaperone HSP82, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Li, J, Qian, X, Hu, J, Sha, B.
Deposit date:2009-01-03
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Molecular chaperone Hsp70/Hsp90 prepares the mitochondrial outer membrane translocon receptor Tom71 for preprotein loading.
J.Biol.Chem., 284, 2009
3FP3
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Crystal structure of Tom71
Descriptor: CHLORIDE ION, SULFATE ION, TPR repeat-containing protein YHR117W
Authors:Li, J, Qian, X, Hu, J, Sha, B.
Deposit date:2009-01-03
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Molecular chaperone Hsp70/Hsp90 prepares the mitochondrial outer membrane translocon receptor Tom71 for preprotein loading.
J.Biol.Chem., 284, 2009
3FP4
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Crystal structure of Tom71 complexed with Ssa1 C-terminal fragment
Descriptor: CHLORIDE ION, SODIUM ION, SULFATE ION, ...
Authors:Li, J, Qian, X, Hu, J, Sha, B.
Deposit date:2009-01-03
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Molecular chaperone Hsp70/Hsp90 prepares the mitochondrial outer membrane translocon receptor Tom71 for preprotein loading.
J.Biol.Chem., 284, 2009
3IEG
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BU of 3ieg by Molmil
Crystal Structure of P58(IPK) TPR Domain at 2.5 A
Descriptor: DnaJ homolog subfamily C member 3
Authors:Tao, J, Sha, B.
Deposit date:2009-07-22
Release date:2010-03-31
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Crystal Structure of P58(IPK) TPR Fragment Reveals the Mechanism for its Molecular Chaperone Activity in UPR.
J.Mol.Biol., 64, 2010
3LCA
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BU of 3lca by Molmil
Structure of Tom71 complexed with Hsp70 Ssa1 C terminal tail indicating conformational plasticity
Descriptor: GLYCEROL, Heat shock protein SSA1, Protein TOM71
Authors:Li, J.Z, Sha, B.D.
Deposit date:2010-01-10
Release date:2010-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:The structural plasticity of Tom71 for mitochondrial precursor translocations.
Acta Crystallogr.,Sect.F, 66, 2010
3NF1
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Crystal structure of the TPR domain of kinesin light chain 1
Descriptor: Kinesin light chain 1
Authors:Tong, Y, Tempel, W, Shen, L, Shen, Y, Nedyalkova, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2010-06-09
Release date:2011-05-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the TPR domain of kinesin light chain 1
to be published
2Y4U
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Crystal structure of human P58(IPK) in space group P312
Descriptor: DNAJ HOMOLOG SUBFAMILY C MEMBER 3
Authors:Svard, M, Biterova, E.I, Bourhis, J.-M, Guy, J.E.
Deposit date:2011-01-10
Release date:2011-08-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The Crystal Structure of the Human Co-Chaperone P58Ipk
Plos One, 6, 2011
2Y4T
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Crystal structure of the human co-chaperone P58(IPK)
Descriptor: DNAJ HOMOLOG SUBFAMILY C MEMBER 3
Authors:Svard, M, Biterova, E.I, Bourhis, J.-M, Guy, J.E.
Deposit date:2011-01-10
Release date:2011-08-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Crystal Structure of the Human Co-Chaperone P58Ipk
Plos One, 6, 2011

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