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8Y14	Beta-catenin Crystal Structure Descriptor: Catenin beta-1 Authors: Tim, F. Deposit date: 2024-01-23 Release date: 2024-03-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Beta-catenin Crystal Structure To Be Published
8Y0G	Human beta-catenin crystal structure Descriptor: Catenin beta-1 Authors: Tim, F. Deposit date: 2024-01-22 Release date: 2024-03-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal protein of human Beta-catenin To Be Published
8QXW	HCMV DNA polymerase processivity factor UL44 unphosphorylated NLS 410-433 bound to mouse importin alpha 2 Descriptor: DNA polymerase processivity factor, Importin subunit alpha-1 Authors: Cross, E.M, Marin, O, Ariawan, D, Aragao, D, Cozza, G, Di Iorio, E, Forwood, J.K, Alvisi, G. Deposit date: 2023-10-25 Release date: 2023-11-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural determinants of phosphorylation-dependent nuclear transport of HCMV DNA polymerase processivity factor UL44. Febs Lett., 598, 2024
8QXX	HCMV DNA polymerase processivity factor UL44 phosphorylated NLS 410-433 bound to mouse importin alpha 2 Descriptor: DNA polymerase processivity factor, Importin subunit alpha-1 Authors: Cross, E.M, Marin, O, Ariawan, D, Aragao, D, Cozza, G, Di Iorio, E, Forwood, J.K, Alvisi, G. Deposit date: 2023-10-25 Release date: 2023-11-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural determinants of phosphorylation-dependent nuclear transport of HCMV DNA polymerase processivity factor UL44. Febs Lett., 598, 2024
8U36	The crystal structure of the classical binding interface of Importin alpha 2 and a nuclear localisation signal sequence in Frog siadenovirus core protein VII Descriptor: Importin subunit alpha-1, PVII, SODIUM ION Authors: Athukorala, A, Donnelly, C.M, Forwood, J.K, Sarker, S. Deposit date: 2023-09-07 Release date: 2023-11-22 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural and functional characterization of nuclear localization signals of pVII protein of Frog siadenovirus To be published
8Q8K	KI Polyomavirus LTA NLS bound to importin alpha 2 Descriptor: Importin subunit alpha-1, Large T antigen Authors: Cross, E.M, Forwood, J.K, Alvisi, G. Deposit date: 2023-08-18 Release date: 2024-02-07 Method: X-RAY DIFFRACTION (2.7 Å) Cite: A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33, 2024
8TUR	Merkel Cell Polyomavirus LTA bipartite NLS bound to importin alpha 2 Descriptor: Importin subunit alpha-1, Truncated large T antigen Authors: Cross, E.M, Forwood, J.K, Alvisi, G. Deposit date: 2023-08-17 Release date: 2024-02-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.15 Å) Cite: A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33, 2024
8TUV	Merkel Cell Polyomavirus LTA NLSm bound to importin alpha 2 Descriptor: 30S ribosomal protein S11, Importin subunit alpha-1, SER-ARG-LYS-ARG-LYS-PHE Authors: Cross, E.M, Forwood, J.K, Alvisi, G. Deposit date: 2023-08-17 Release date: 2024-02-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33, 2024
8TUT	Merkel Cell Polyomavirus LTA NLSct bound to importin alpha 2 Descriptor: Importin subunit alpha-1, PRO-PRO-LYS-PRO-LYS-LYS-ASN-ARG-GLU Authors: Cross, E.M, Forwood, J.K, Alvisi, G. Deposit date: 2023-08-17 Release date: 2024-02-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.55 Å) Cite: A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33, 2024
8TUQ	STL Polyomavirus LTA NLS bound to importin alpha 2 Descriptor: Importin subunit alpha-1, Large T antigen Authors: Donnelly, C.M, Cross, E.M, Forwood, J.K, Alvisi, G. Deposit date: 2023-08-17 Release date: 2024-02-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2 Å) Cite: A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33, 2024
8TUU	MW Polyomavirus LTA bipartite NLS bound to importin alpha 2 Descriptor: Importin subunit alpha-1, Large T-antigen Authors: Cross, E.M, Forwood, J.K, Alvisi, G. Deposit date: 2023-08-17 Release date: 2024-02-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.5 Å) Cite: A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33, 2024
8TUS	WU Polyomavirus LTA NLS bound to importin alpha 2 Descriptor: Importin subunit alpha-1, Large T antigen Authors: Donnelly, C.M, Cross, E.M, Forwood, J.K, Alvisi, G. Deposit date: 2023-08-17 Release date: 2024-02-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.6 Å) Cite: A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33, 2024
8SV0	The crystal structure of the classical binding interface of Importin alpha 2 and nuclear localisation signal sequence in Psittacine siadenovirus core protein VII Descriptor: Importin subunit alpha-1, SODIUM ION, protein VII Authors: Athukorala, A, Sarker, S, Forwood, J.K, Donnelly, C.M. Deposit date: 2023-05-14 Release date: 2023-05-31 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural and functional characterization of nuclear localization signal of pVII protein of psittacine siadenovirus F demonstrates an independent transport of pVII protein into the nucleus To Be Published
8SUD	JC Polyomavirus LTA NLS bound to importin alpha 2 Descriptor: Importin subunit alpha-1, Large T antigen Authors: Cross, E.M, Forwood, J.K, Alvisi, G. Deposit date: 2023-05-12 Release date: 2024-02-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.1 Å) Cite: A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33, 2024
8SG7	Adeno-Associated Virus Bat origin capsid protein basic regions in complex with importin-alpha 2 Descriptor: Importin subunit alpha-1, VP1 capsid Authors: Hoad, M, Forwood, J.K. Deposit date: 2023-04-11 Release date: 2023-07-19 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural basis for nuclear import of bat adeno-associated virus capsid protein. J.Gen.Virol., 105, 2024
8J07	96nm repeat of human respiratory doublet microtubule and associated axonemal complexes Descriptor: ACTA2, Axonemal dynein light intermediate polypeptide 1, Calaxin, ... Authors: Gui, M, Brown, A. Deposit date: 2023-04-09 Release date: 2023-07-26 Last modified: 2023-08-02 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Axonemal structures reveal mechanoregulatory and disease mechanisms. Nature, 618, 2023
8GCN	CRYO-EM STRUCTURE OF IMPORTIN ALPHA1/BETA HETERODIMER Descriptor: Importin subunit alpha-1, Importin subunit beta-1 Authors: Ko, Y, Cingolani, G. Deposit date: 2023-03-02 Release date: 2024-03-06 Method: ELECTRON MICROSCOPY (3.95 Å) Cite: CRYO-EM STRUCTURE OF IMPORTIN ALPHA1/BETA HETERODIMER To Be Published
8GAI	Cavia porcellus (guinea pig) importin-alpha 1 in complex with Bimax2 peptide Descriptor: Bimax2, Importin subunit alpha Authors: Hawker, J.E, Forwood, J.K, Donnelly, C.M, Stewart, M. Deposit date: 2023-02-22 Release date: 2023-04-05 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Crystal structure of Cavia porcellus (guinea pig) importin-alpha 1 in complex with bimax2 peptide To Be Published
8G8Q	RelB NLS in complex with Importin alpha 2 Descriptor: Importin subunit alpha-1, bacterial peptide, monopartite p52 NLS Authors: Tsimbslyuk, S, Stewart, M, Forwood, J.K. Deposit date: 2023-02-19 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.6 Å) Cite: p52 monopartite NLS in complex with Importin alpha 2 To Be Published
8G8R	RelB NLS in complex with Importin alpha 2 Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Importin subunit alpha-1, Transcription factor RelB Authors: Tsimbslyuk, S, Stewart, M, Forwood, J.K. Deposit date: 2023-02-19 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.6 Å) Cite: monopartite p52 NLS in complex with Importin alpha 2 To Be Published
8G8S	bipartite p52 NLS in complex with Importin alpha 2 Descriptor: Importin subunit alpha-1, Nuclear factor NF-kappa-B p100 subunit isoform X1 Authors: Tsimbslyuk, S, Stewart, M, Forwood, J.K. Deposit date: 2023-02-19 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.1 Å) Cite: p52 bipartite NLS in complex with Importin alpha 2 To Be Published
8G4J	Crystal structure of Cavia porcellus (guinea pig) importin-alpha 1 in cargo-free state Descriptor: Importin subunit alpha Authors: Hawker, J.E, Roby, J.A, Stewart, M, Forwood, J.K. Deposit date: 2023-02-09 Release date: 2023-02-22 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Crystal structure of Cavia porcellus (guinea pig) importin-alpha 1 in cargo-free state To Be Published
8FZK	Dimeric human importin alpha subunit Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Importin subunit alpha-1, MAGNESIUM ION Authors: Donnelly, C.M, Stewart, M, Forwood, J.K. Deposit date: 2023-01-29 Release date: 2023-02-08 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Dimeric human importin alpha subunit To Be Published
8FZM	Human importin alpha 3 in complex with Bimax2 peptide Descriptor: Bimax2, Importin subunit alpha-3 Authors: Donnelly, C.M, Forwood, J.K. Deposit date: 2023-01-29 Release date: 2023-02-08 Method: X-RAY DIFFRACTION (3 Å) Cite: Human importin alpha 3 in complex with Bimax2 peptide To Be Published
8FUC	Crystal structure of mouse Importin alpha in complex with Hendra virus matrix protein minor site NLS2 Descriptor: Contaminant peptide KKLARE, Importin subunit alpha-1, Matrix protein Authors: Donnelly, C.M, Basler, C.F, Scott, C, Forwood, J.K. Deposit date: 2023-01-17 Release date: 2023-01-25 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Henipavirus Matrix Protein Employs a Non-Classical Nuclear Localization Signal Binding Mechanism. Viruses, 15, 2023

 

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