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8G5A	X-31 hemagglutinin in complex with FL-1061 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, FL-1086 Fab heavy chain, FL-1086 light chain, ... Authors: Windsor, I.W, Thornlow, D, Schmidt, A.G. Deposit date: 2023-02-12 Release date: 2024-02-21 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Antibodies elicited by a hyperglycoslated immunogen To Be Published
8G5B	Influenza A H3N2 X-31 Hemagglutinin in complex with FL-1061 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, FL-1061 heavy chain, FL-1061 light chain, ... Authors: Windsor, I.W, Thornlow, D, Schmidt, A.G. Deposit date: 2023-02-12 Release date: 2024-02-21 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Fabs elicited by hyperglycosylated immunogen To Be Published
8TJ6	CRYSTAL STRUCTURE OF THE A/Beijing/353/1989(H3N2) INFLUENZA VIRUS HEMAGGLUTININ WITH HUMAN RECEPTOR ANALOG 6'-SLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Wu, N.C, Zhu, X, Wilson, I.A. Deposit date: 2023-07-20 Release date: 2024-02-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site. Cell Host Microbe, 32, 2024
8TJ9	CRYSTAL STRUCTURE OF THE A/Michigan/15/2014(H3N2) INFLUENZA VIRUS HEMAGGLUTININ WITH HUMAN RECEPTOR ANALOG 6'-SLNLN Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... Authors: Wu, N.C, Zhu, X, Wilson, I.A. Deposit date: 2023-07-20 Release date: 2024-02-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site. Cell Host Microbe, 32, 2024
8TJB	CRYSTAL STRUCTURE OF THE A/Texas/73/2017(H3N2) INFLUENZA VIRUS HEMAGGLUTININ WITH HUMAN RECEPTOR ANALOG 6'-SLNLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... Authors: Wu, N.C, Zhu, X, Wilson, I.A. Deposit date: 2023-07-20 Release date: 2024-02-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site. Cell Host Microbe, 32, 2024
8TJA	CRYSTAL STRUCTURE OF THE A/Ecuador/1374/2016(H3N2) INFLUENZA VIRUS HEMAGGLUTININ WITH HUMAN RECEPTOR ANALOG 6'-SLNLN Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... Authors: Wu, N.C, Zhu, X, Wilson, I.A. Deposit date: 2023-07-20 Release date: 2024-02-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site. Cell Host Microbe, 32, 2024
8TJ7	CRYSTAL STRUCTURE OF THE A/Shandong/9/1993(H3N2) INFLUENZA VIRUS HEMAGGLUTININ WITH HUMAN RECEPTOR ANALOG 6'-SLNLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... Authors: Wu, N.C, Zhu, X, Wilson, I.A. Deposit date: 2023-07-20 Release date: 2024-02-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site. Cell Host Microbe, 32, 2024
8TJ8	CRYSTAL STRUCTURE OF THE A/Moscow/10/1999(H3N2) INFLUENZA VIRUS HEMAGGLUTININ WITH HUMAN RECEPTOR ANALOG 6'-SLNLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... Authors: Wu, N.C, Zhu, X, Wilson, I.A. Deposit date: 2023-07-20 Release date: 2024-02-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.56 Å) Cite: Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site. Cell Host Microbe, 32, 2024
8TJ4	CRYSTAL STRUCTURE OF THE A/Bangkok/1/1979(H3N2) INFLUENZA VIRUS HEMAGGLUTININ WITH HUMAN RECEPTOR ANALOG 6'-SLNLN Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Wu, N.C, Zhu, X, Wilson, I.A. Deposit date: 2023-07-20 Release date: 2024-02-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site. Cell Host Microbe, 32, 2024
8PK3	CryoEM reconstruction of hemagglutinin HK68 of Influenza A virus bound to an Affimer reagent Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Affimer molecule (A31), ... Authors: Debski-Antoniak, O, Flynn, A, Klebl, D.P, Tiede, C, Muench, S, Tomlinson, D, Fontana, J. Deposit date: 2023-06-24 Release date: 2024-01-03 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Exploiting the Affimer platform against influenza A virus To Be Published
8UR7	I53_dn5 nanoparticle displaying the trimeric HA heads with heptad domain, TH-6heptad-I53_dn5 (local refinement of TH-6heptad) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Trimer head HA,Hemagglutinin HA1 chain Authors: Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2023-10-25 Release date: 2023-12-27 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Antigen spacing on protein nanoparticles influences antibody responses to vaccination. Cell Rep, 42, 2023
8UR5	I53_dn5 nanoparticle displaying the trimeric HA heads with heptad domain, TH-1heptad-I53_dn5 (local refinement of TH-1heptad) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Trimer head HA,Hemagglutinin HA1 chain Authors: Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2023-10-25 Release date: 2023-12-27 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Antigen spacing on protein nanoparticles influences antibody responses to vaccination. Cell Rep, 42, 2023
8F38	Cryo-EM structure of X6 COBRA (H1N1) hemagglutinin bound to CR6261 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR6261 Fab heavy chain, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2022-11-09 Release date: 2023-12-13 Method: ELECTRON MICROSCOPY (2.64 Å) Cite: Cryo-EM structure of X6 COBRA (H1N1) hemagglutinin bound to CR6261 Fab To be published
8TP7	H2 hemagglutinin (A/Singapore/1/1957) in complex with Sa-targeting Fab 4-1-1G03 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of monoclonal antibody 4-1-1G03, ... Authors: Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. Deposit date: 2023-08-04 Release date: 2023-10-11 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
8TP4	H2 hemagglutinin (A/Singapore/1/1957) in complex with RBS-targeting Fab 1-1-1E04 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 1-1-1E04, ... Authors: Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. Deposit date: 2023-08-04 Release date: 2023-10-11 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
8TPA	H1 hemagglutinin (NC99) in complex with medial-junction-targeting Fab 2-2-1G06 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 2-2-1G06, ... Authors: Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. Deposit date: 2023-08-04 Release date: 2023-10-11 Method: ELECTRON MICROSCOPY (3 Å) Cite: Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
8TP6	H2 hemagglutinin (A/Singapore/1/1957) in complex with RBS-targeting Fab 4-1-1E02 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 4-1-1E02 Fab, ... Authors: Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. Deposit date: 2023-08-04 Release date: 2023-10-11 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
8TP3	H1 hemagglutinin (NC99) in complex with RBS-targeting Fab 1-1-1F05 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 1-1-1F05, ... Authors: Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. Deposit date: 2023-08-04 Release date: 2023-10-11 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
8TP2	H2 hemagglutinin (A/Singapore/1/1957) in complex with RBS-targeting 1-1-1F05 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 1-1-1F05, ... Authors: Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. Deposit date: 2023-08-04 Release date: 2023-10-11 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
8TP9	H2 hemagglutinin (A/Singapore/1/1957) in complex with medial-junction-targeting Fab 2-2-1G06 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 2-2-1G06, ... Authors: Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. Deposit date: 2023-08-04 Release date: 2023-10-11 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
8TP5	H1 hemagglutinin (NC99) in complex with RBS-targeting Fab 1-1-1E04 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 1-1-1E04, ... Authors: Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. Deposit date: 2023-08-04 Release date: 2023-10-11 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
7TRH	Human antibody K03.28 in complex with the influenza hemagglutinin head domain of A/California/07/2009(H1N1)(X-181) Descriptor: Hemagglutinin, K03.28 Fab heavy chain, K03.28 Fab lambda light chain Authors: McCarthy, K.R. Deposit date: 2022-01-28 Release date: 2023-08-02 Last modified: 2024-01-03 Method: X-RAY DIFFRACTION (3 Å) Cite: A new class of antibodies that overcomes a steric barrier to cross-group neutralization of influenza viruses. Plos Biol., 21, 2023
7TRI	Human antibody S8V1-172 in complex with the influenza hemagglutinin head domain of A/Sydney/05/1997(H3N2) Descriptor: Hemagglutinin, S8V1-172 Fab heavy chain, S8V1-172 Fab kappa light chain, ... Authors: McCarthy, K.R. Deposit date: 2022-01-28 Release date: 2023-08-02 Last modified: 2024-01-03 Method: X-RAY DIFFRACTION (3.6 Å) Cite: A new class of antibodies that overcomes a steric barrier to cross-group neutralization of influenza viruses. Plos Biol., 21, 2023
8SK7	Cryo-EM structure of designed Influenza HA binder, HA_20, bound to Influenza HA (Strain: Iowa43) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HA_20 minibinder (RFdiffusion-designed), ... Authors: Borst, A.J, Bennett, N.R. Deposit date: 2023-04-18 Release date: 2023-06-14 Last modified: 2023-09-13 Method: ELECTRON MICROSCOPY (2.93 Å) Cite: De novo design of protein structure and function with RFdiffusion. Nature, 620, 2023
8DIS	CryoEM structure of Influenza A virus A/Melbourne/1/1946 (H1N1) hemagglutinin bound to CR6261 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR6261 Fab heavy chain, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2022-06-29 Release date: 2023-06-07 Method: ELECTRON MICROSCOPY (2.62 Å) Cite: CryoEM structure of Influenza A virus A/Melbourne/1/1946 (H1N1) hemagglutinin bound to CR6261 Fab To be published

 

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