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6AR0
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BU of 6ar0 by Molmil
Structure of human SLMAP FHA domain
Descriptor: Sarcolemmal membrane-associated protein
Authors:Ni, L, Luo, X.
Deposit date:2017-08-21
Release date:2018-07-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK.
Elife, 6, 2017
2PIE
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BU of 2pie by Molmil
Crystal structure of the FHA domain of RNF8 in complex with its optimal phosphopeptide
Descriptor: E3 ubiquitin-protein ligase RNF8, phosphopeptide
Authors:Grant, R.A, Yaffe, M.B.
Deposit date:2007-04-13
Release date:2007-12-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein Assembly.
Cell(Cambridge,Mass.), 131, 2007
6HC1
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BU of 6hc1 by Molmil
Bdellovibrio bacteriovorus DgcB FHA in complex with phosphorylated N-terminal peptide
Descriptor: DgcB N-terminus, phosphorylated, GGDEF domain protein
Authors:Lovering, A.L, Meek, R.W.
Deposit date:2018-08-13
Release date:2019-08-28
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Structural basis for activation of a diguanylate cyclase required for bacterial predation in Bdellovibrio.
Nat Commun, 10, 2019
3PO8
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BU of 3po8 by Molmil
Structural and functional analysis of phosphothreonine-dependent FHA domain interactions
Descriptor: PHOSPHATE ION, Putative uncharacterized protein TB39.8
Authors:Pennell, S, Smerdon, S.J.
Deposit date:2010-11-22
Release date:2011-01-26
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural and functional analysis of phosphothreonine-dependent FHA domain interactions
Structure, 18, 2010
3VA4
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BU of 3va4 by Molmil
Crystal structure of the mammalian MDC1 FHA domain complexed with CHK2 pThr68 peptide
Descriptor: Mediator of DNA damage checkpoint protein 1, Serine/threonine-protein kinase Chk2
Authors:Wu, H.H, Wu, P.Y, Huang, K.F, Kao, Y.Y, Tsai, M.D.
Deposit date:2011-12-28
Release date:2012-02-01
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Structural Delineation of MDC1-FHA Domain Binding with CHK2-pThr68.
Biochemistry, 2012
4H87
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BU of 4h87 by Molmil
Crystal structure of a FHA domain of kanadaptin (SLC4A1AP) from Homo sapiens at 1.55 A resolution
Descriptor: GLYCEROL, Kanadaptin, SULFATE ION
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2012-09-21
Release date:2012-10-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure of a FHA domain of kanadaptin (SLC4A1AP) from Homo sapiens at 1.55 A resolution
To be published
6AR2
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BU of 6ar2 by Molmil
Structure of human SLMAP FHA domain in complex with pMST2
Descriptor: ASP-GLY-TPO-MET-LYS-ARG, Sarcolemmal membrane-associated protein
Authors:Osinski, A, Ni, L, Luo, X.
Deposit date:2017-08-21
Release date:2018-07-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK.
Elife, 6, 2017
1G6G
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BU of 1g6g by Molmil
X-RAY STRUCTURE OF THE N-TERMINAL FHA DOMAIN FROM S. CEREVISIAE RAD53P IN COMPLEX WITH A PHOSPHOTHREONINE PEPTIDE AT 1.6 A RESOLUTION
Descriptor: PROTEIN KINASE RAD53, SER-LEU-GLU-VAL-TPO-GLU-ALA-ASPALA-THR-PHE-ALA-LYS
Authors:Durocher, D, Taylor, I.A.
Deposit date:2000-11-06
Release date:2000-12-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms.
Mol.Cell, 6, 2000
3UMZ
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BU of 3umz by Molmil
Crystal Structure of the human MDC1 FHA Domain
Descriptor: Mediator of DNA damage checkpoint protein 1
Authors:Luo, S, Ye, K.
Deposit date:2011-11-15
Release date:2012-01-25
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain
Nucleic Acids Res., 40, 2012
7RJ3
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BU of 7rj3 by Molmil
Crystal Structure of the Forkhead Associated (FHA) Domain of the Glycogen Accumulation Regulator (GarA) from Mycobacterium tuberculosis
Descriptor: DI(HYDROXYETHYL)ETHER, Glycogen accumulation regulator GarA
Authors:Minasov, G, Shuvalova, L, Pshenychnyi, S, Dubrovska, I, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2021-07-20
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Crystal Structure of the Forkhead Associated (FHA) Domain of the Glycogen Accumulation Regulator (GarA) from Mycobacterium tuberculosis.
To Be Published
5YYX
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BU of 5yyx by Molmil
Crystal Structure of the MEK1 FHA domain
Descriptor: Meiosis-specific serine/threonine-protein kinase MEK1
Authors:Xie, C, Li, F, Jiang, Y, Wu, J, Shi, Y.
Deposit date:2017-12-11
Release date:2018-10-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.684 Å)
Cite:Structural insights into the recognition of phosphorylated Hop1 by Mek1
Acta Crystallogr D Struct Biol, 74, 2018
3UNN
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BU of 3unn by Molmil
Monomeric structure of the human MDC1 FHA domain in complex with an MDC1 phospho-T4 peptide
Descriptor: Mediator of DNA damage checkpoint protein 1, phospho-T4 peptide from Mediator of DNA damage checkpoint protein 1
Authors:Luo, S, Ye, K.
Deposit date:2011-11-16
Release date:2012-01-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain
Nucleic Acids Res., 40, 2012
3VPY
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BU of 3vpy by Molmil
Crystal structure of Arabidopsis DDL FHA domain
Descriptor: FHA domain-containing protein DDL
Authors:Yuan, Y.A, Machida, S.
Deposit date:2012-03-15
Release date:2013-02-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of Arabidopsis thaliana Dawdle Forkhead-Associated Domain reveals a conserved phospho-threonine recognition cleft for Dicer-like1 binding.
Mol Plant, 2013
5DJO
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BU of 5djo by Molmil
Crystal structure of the CC1-FHA tandem of Kinesin-3 KIF13A
Descriptor: ACETIC ACID, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ...
Authors:Ren, J.Q, Li, W, Huo, L, Feng, W.
Deposit date:2015-09-02
Release date:2015-12-30
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structural Correlation of the Neck Coil with the Coiled-coil (CC1)-Forkhead-associated (FHA) Tandem for Active Kinesin-3 KIF13A
J.Biol.Chem., 291, 2016
3VA1
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BU of 3va1 by Molmil
Crystal structure of the mammalian MDC1 FHA domain
Descriptor: Mediator of DNA damage checkpoint protein 1, SULFATE ION
Authors:Wu, H.H, Wu, P.Y, Huang, K.F, Kao, Y.Y, Tsai, M.D.
Deposit date:2011-12-28
Release date:2012-02-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structural Delineation of MDC1-FHA Domain Binding with CHK2-pThr68.
Biochemistry, 2012
5A8I
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BU of 5a8i by Molmil
Crystal structure of the FHA domain of ArnA from Sulfolobus acidocaldarius
Descriptor: ARNA, GLYCEROL, SULFATE ION
Authors:Hoffmann, L, Anders, K, Reimann, J, Linne, U, Essen, L.-O, Albers, S.-V.
Deposit date:2015-07-16
Release date:2016-06-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Phosphorylation-Dependent Interaction between an Archaeal Von Willebrand and Fha Domain Recruits Arna-Arnb Complex to DNA for Repression of Motility
To be Published
8WWY
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BU of 8wwy by Molmil
Crystal structure of mouse TIFA/TIFAB heterodimer
Descriptor: (2R,5R)-hexane-2,5-diol, TRAF-interacting protein with FHA domain-containing protein A, TRAF-interacting protein with FHA domain-containing protein B
Authors:Nakamura, T.
Deposit date:2023-10-27
Release date:2024-03-13
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:TIFAB regulates the TIFA-TRAF6 signaling pathway involved in innate immunity by forming a heterodimer complex with TIFA.
Proc.Natl.Acad.Sci.USA, 121, 2024
6HBZ
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BU of 6hbz by Molmil
Bdellovibrio bacteriovorus DgcB Full-length
Descriptor: 1,2-ETHANEDIOL, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CHLORIDE ION, ...
Authors:Lovering, A.L, Meek, R.W.
Deposit date:2018-08-13
Release date:2019-08-28
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structural basis for activation of a diguanylate cyclase required for bacterial predation in Bdellovibrio.
Nat Commun, 10, 2019
5YYZ
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BU of 5yyz by Molmil
Crystal structure of the MEK1 FHA domain in complex with the HOP1 pThr318 peptide.
Descriptor: Meiosis-specific protein HOP1, Meiosis-specific serine/threonine-protein kinase MEK1
Authors:Xie, C, Li, F, Jiang, Y, Wu, J, Shi, Y.
Deposit date:2017-12-11
Release date:2018-10-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Structural insights into the recognition of phosphorylated Hop1 by Mek1
Acta Crystallogr D Struct Biol, 74, 2018
6CCD
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BU of 6ccd by Molmil
The crystal structure of Mycobacterium tuberculosis Rv1747 FHA-1
Descriptor: ABC transporter ATP-binding/permease protein Rv1747, SULFATE ION
Authors:Gay, L.M, Gee, C.L, Alber, T.
Deposit date:2018-02-06
Release date:2018-06-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Biophysical Characterization of the Tandem FHA Domain Regulatory Module from the Mycobacterium tuberculosis ABC Transporter Rv1747.
Structure, 26, 2018
3UOT
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BU of 3uot by Molmil
Crystal Structure of MDC1 FHA Domain in Complex with a Phosphorylated Peptide from the MDC1 N-terminus
Descriptor: Mediator of DNA damage checkpoint protein 1
Authors:Clapperton, J.A, Lloyd, J, Haire, L.F, Li, J, Smerdon, S.J.
Deposit date:2011-11-17
Release date:2011-12-28
Last modified:2012-07-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator.
Nucleic Acids Res., 40, 2012
3UNM
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BU of 3unm by Molmil
Crystal Structure of The Human MDC1 FHA Domain
Descriptor: Mediator of DNA damage checkpoint protein 1
Authors:Luo, S, Ye, K.
Deposit date:2011-11-16
Release date:2012-01-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain
Nucleic Acids Res., 40, 2012
3ELS
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BU of 3els by Molmil
Crystal Structure of Yeast Pml1p, Residues 51-204
Descriptor: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
Authors:Trowitzsch, S, Weber, G, Luehrmann, R, Wahl, M.C.
Deposit date:2008-09-23
Release date:2009-02-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the Pml1p subunit of the yeast precursor mRNA retention and splicing complex.
J.Mol.Biol., 385, 2009
6A8W
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BU of 6a8w by Molmil
Crystal structure of the FHA domain of Far9
Descriptor: Vacuolar protein sorting-associated protein 64
Authors:Chen, M, Zhang, W.Q, Zhou, Z.C.
Deposit date:2018-07-10
Release date:2019-07-10
Method:X-RAY DIFFRACTION (1.844 Å)
Cite:Topological Structure and Dynamic Assembly of the STRIPAK Complex
To be published
6HC0
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BU of 6hc0 by Molmil
Bdellovibrio bacteriovorus DgcB FHA domain, tail complex
Descriptor: DgcB N-terminus, FORMIC ACID, GGDEF domain protein
Authors:Lovering, A.L, Meek, R.W.
Deposit date:2018-08-13
Release date:2019-08-28
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structural basis for activation of a diguanylate cyclase required for bacterial predation in Bdellovibrio.
Nat Commun, 10, 2019

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