1RLA
| THREE-DIMENSIONAL STRUCTURE OF RAT LIVER ARGINASE, THE BINUCLEAR MANGANESE METALLOENZYME OF THE UREA CYCLE | Descriptor: | ARGINASE, MANGANESE (II) ION | Authors: | Kanyo, Z, Scolnick, L, Ash, D, Christianson, D.W. | Deposit date: | 1996-08-15 | Release date: | 1997-10-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of a unique binuclear manganese cluster in arginase. Nature, 383, 1996
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3RLA
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4RLA
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5RLA
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2RLA
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2CEV
| ARGINASE FROM BACILLUS CALDEVELOX, NATIVE STRUCTURE AT PH 8.5 | Descriptor: | GUANIDINE, MANGANESE (II) ION, PROTEIN (ARGINASE) | Authors: | Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N. | Deposit date: | 1999-03-10 | Release date: | 1999-04-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily. Structure Fold.Des., 7, 1999
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1CEV
| ARGINASE FROM BACILLUS CALDOVELOX, NATIVE STRUCTURE AT PH 5.6 | Descriptor: | MANGANESE (II) ION, PROTEIN (ARGINASE) | Authors: | Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N. | Deposit date: | 1999-03-12 | Release date: | 1999-04-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily. Structure Fold.Des., 7, 1999
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4CEV
| ARGINASE FROM BACILLUS CALDEVELOX, L-ORNITHINE COMPLEX | Descriptor: | GUANIDINE, L-ornithine, MANGANESE (II) ION, ... | Authors: | Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N. | Deposit date: | 1999-03-15 | Release date: | 1999-04-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily. Structure Fold.Des., 7, 1999
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3CEV
| ARGINASE FROM BACILLUS CALDEVELOX, COMPLEXED WITH L-ARGININE | Descriptor: | ARGININE, MANGANESE (II) ION, PROTEIN (ARGINASE) | Authors: | Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N. | Deposit date: | 1999-03-15 | Release date: | 1999-04-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily. Structure Fold.Des., 7, 1999
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5CEV
| ARGINASE FROM BACILLUS CALDEVELOX, L-LYSINE COMPLEX | Descriptor: | GUANIDINE, LYSINE, MANGANESE (II) ION, ... | Authors: | Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N. | Deposit date: | 1999-03-16 | Release date: | 1999-04-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily. Structure Fold.Des., 7, 1999
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1D3V
| CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH 2(S)-AMINO-6-BORONOHEXANOIC ACID, AN L-ARGININE ANALOG | Descriptor: | 2(S)-AMINO-6-BORONOHEXANOIC ACID, MANGANESE (II) ION, PROTEIN (ARGINASE) | Authors: | Cox, J.D, Kim, N.N, Traish, A.M, Christianson, D.W. | Deposit date: | 1999-10-01 | Release date: | 1999-11-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Arginase-boronic acid complex highlights a physiological role in erectile function. Nat.Struct.Biol., 6, 1999
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1HQ5
| CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH S-(2-BORONOETHYL)-L-CYSTEINE, AN L-ARGININE ANALOGUE | Descriptor: | ARGINASE 1, MANGANESE (II) ION, S-2-(BORONOETHYL)-L-CYSTEINE | Authors: | Kim, N.N, Cox, J.D, Baggio, R.F, Emig, F.A, Mistry, S.K, Harper, S.L, Speicher, D.W, Morris Jr, S.M, Ash, D.E, Traish, A, Christianson, D.W. | Deposit date: | 2000-12-14 | Release date: | 2001-04-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Probing erectile function: S-(2-boronoethyl)-L-cysteine binds to arginase as a transition state analogue and enhances smooth muscle relaxation in human penile corpus cavernosum. Biochemistry, 40, 2001
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1HQF
| CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH N-HYDROXY-L-ARGININE | Descriptor: | ARGINASE 1, MANGANESE (II) ION, N-OMEGA-HYDROXY-L-ARGININE | Authors: | Cox, J.D, Cama, E, Colleluori, D.M, Ash, D.E, Christianson, D.W. | Deposit date: | 2000-12-16 | Release date: | 2001-04-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase. Biochemistry, 40, 2001
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1HQG
| CRYSTAL STRUCTURE OF THE H141C ARGINASE VARIANT COMPLEXED WITH PRODUCTS ORNITHINE AND UREA | Descriptor: | ARGINASE 1, L-ornithine, MANGANESE (II) ION, ... | Authors: | Cox, J.D, Cama, E, Colleluori, D.M, Ash, D.E, Christianson, D.W. | Deposit date: | 2000-12-16 | Release date: | 2001-04-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase. Biochemistry, 40, 2001
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1HQH
| CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH NOR-N-HYDROXY-L-ARGININE | Descriptor: | ARGINASE 1, MANGANESE (II) ION, NOR-N-OMEGA-HYDROXY-L-ARGININE | Authors: | Cox, J.D, Cama, E, Colleluori, D.M, Ash, D.E, Christianson, D.W. | Deposit date: | 2000-12-16 | Release date: | 2001-04-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase. Biochemistry, 40, 2001
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1HQX
| R308K ARGINASE VARIANT | Descriptor: | ARGINASE, MANGANESE (II) ION | Authors: | Lavulo, L.T, Sossong Jr, T.M, Brigham-Burke, M.R, Doyle, M.L, Cox, J.D, Christianson, D.W, Ash, D.E. | Deposit date: | 2000-12-20 | Release date: | 2001-06-06 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Subunit-subunit interactions in trimeric arginase. Generation of active monomers by mutation of a single amino acid. J.Biol.Chem., 276, 2001
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1GQ7
| PROCLAVAMINATE AMIDINO HYDROLASE FROM STREPTOMYCES CLAVULIGERUS | Descriptor: | MANGANESE (II) ION, PROCLAVAMINATE AMIDINO HYDROLASE | Authors: | Elkins, J.M, Clifton, I.J, Hernandez, H, Robinson, C.V, Schofield, C.J, Hewitson, K.S. | Deposit date: | 2001-11-20 | Release date: | 2002-06-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Oligomeric structure of proclavaminic acid amidino hydrolase: evolution of a hydrolytic enzyme in clavulanic acid biosynthesis. Biochem. J., 366, 2002
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1GQ6
| PROCLAVAMINATE AMIDINO HYDROLASE FROM STREPTOMYCES CLAVULIGERUS | Descriptor: | MANGANESE (II) ION, PROCLAVAMINATE AMIDINO HYDROLASE | Authors: | Elkins, J.M, Clifton, I.J, Hernandez, H, Robinson, C.V, Schofield, C.J, Hewitson, K.S. | Deposit date: | 2001-11-20 | Release date: | 2002-06-06 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Oligomeric Structure of Proclavaminic Acid Amidino Hydrolase: Evolution of a Hydrolytic Enzyme in Clavulanic Acid Biosynthesis Biochem.J., 366, 2002
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1P8S
| Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I. | Descriptor: | Arginase 1, MANGANESE (II) ION | Authors: | Cama, E, Emig, F.A, Ash, D.E, Christianson, D.W. | Deposit date: | 2003-05-07 | Release date: | 2003-06-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural and functional importance of first-shell metal ligands in the binuclear
manganese cluster of arginase I Biochemistry, 42, 2003
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1P8M
| Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I. | Descriptor: | Arginase 1, MANGANESE (II) ION | Authors: | Cama, E, Emig, F.A, Ash, E.-D, Christianson, D.W. | Deposit date: | 2003-05-07 | Release date: | 2003-06-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase I. Biochemistry, 42, 2003
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1P8R
| Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I. | Descriptor: | Arginase 1, CHLORIDE ION, MANGANESE (II) ION, ... | Authors: | Cama, E, Emig, F.A, Ash, D.E, Christianson, D.W. | Deposit date: | 2003-05-07 | Release date: | 2003-06-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and functional importance of first-shell metal ligands in the binuclear
manganese cluster of arginase I Biochemistry, 42, 2003
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1P8P
| Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I. | Descriptor: | Arginase 1, MANGANESE (II) ION | Authors: | Cama, E, Emig, F.A, Ash, D.E, Christianson, D.W. | Deposit date: | 2003-05-07 | Release date: | 2003-06-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and functional importance of first-shell metal ligands in the binuclear
manganese cluster of arginase I Biochemistry, 42, 2003
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1P8Q
| Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Cluster of Arginase I. | Descriptor: | Arginase 1, GLYCEROL, MANGANESE (II) ION | Authors: | Cama, E, Emig, F.A, Ash, D.E, Christianson, D.W. | Deposit date: | 2003-05-07 | Release date: | 2003-06-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structural and functional importance of first-shell metal ligands in the binuclear
manganese cluster of arginase I Biochemistry, 42, 2003
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1P8O
| Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I. | Descriptor: | Arginase 1, MANGANESE (II) ION | Authors: | Cama, E, Emig, F.A, Ash, D.E, Christianson, D.W. | Deposit date: | 2003-05-07 | Release date: | 2003-06-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.96 Å) | Cite: | Structural and functional importance of first-shell metal ligands in the binuclear
manganese cluster of arginase I Biochemistry, 42, 2003
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1P8N
| Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I. | Descriptor: | Arginase 1, GLYCEROL, MANGANESE (II) ION | Authors: | Cama, E, Emig, F.A, Ash, D.E, Christianson, D.W. | Deposit date: | 2003-05-07 | Release date: | 2003-06-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural and functional importance of first-shell metal ligands in the binuclear
manganese cluster of arginase I Biochemistry, 42, 2003
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