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1DPG	GLUCOSE 6-PHOSPHATE DEHYDROGENASE FROM LEUCONOSTOC MESENTEROIDES Descriptor: GLUCOSE 6-PHOSPHATE DEHYDROGENASE, PHOSPHATE ION Authors: Adams, M.J, Rowland, P, Gover, S. Deposit date: 1995-12-04 Release date: 1996-03-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: The three-dimensional structure of glucose 6-phosphate dehydrogenase from Leuconostoc mesenteroides refined at 2.0 A resolution. Structure, 2, 1994
1E77	COMPLEX OF ACTIVE MUTANT (Q365->C) OF GLUCOSE 6-PHOSPHATE DEHYDROGENASE FROM LEUCONOSTOC MESENTEROIDES WITH SUBSTRATE Descriptor: 6-O-phosphono-beta-D-glucopyranose, CALCIUM ION, GLUCOSE 6-PHOSPHATE 1-DEHYDROGENASE Authors: Adams, M.J, Vandeputte-Rutten, L, Gover, S. Deposit date: 2000-08-24 Release date: 2000-12-11 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.69 Å) Cite: An Examination of the Role of Asp-177 in the His-Asp Catalytic Dyad of Leuconostoc Mesenteroides Glucose 6-Phosphate Dehydrogenase: X-Ray Structure and Ph Dependence of Kinetic Parameters of the D177N Mutant Enzyme Biochemistry, 39, 2000
1E7M	ACTIVE SITE MUTANT (D177->N) OF GLUCOSE 6-PHOSPHATE DEHYDROGENASE FROM LEUCONOSTOC MESENTEROIDES Descriptor: CALCIUM ION, GLUCOSE 6-PHOSPHATE 1-DEHYDROGENASE Authors: Adams, M.J, Cosgrove, M.S, Gover, S. Deposit date: 2000-08-30 Release date: 2000-12-11 Last modified: 2019-05-22 Method: X-RAY DIFFRACTION (2.54 Å) Cite: An Examination of the Role of Asp-177 in the His-Asp Catalytic Dyad of Leuconostoc Mesenteroides Glucose 6-Phosphate Dehydrogenase: X-Ray Structure and Ph Dependence of Kinetic Parameters of the D177N Mutant Enzyme Biochemistry, 39, 2000
1E7Y	ACTIVE SITE MUTANT (D177->N) OF GLUCOSE 6-PHOSPHATE DEHYDROGENASE FROM LEUCONOSTOC MESENTEROIDES COMPLEXED WITH SUBSTRATE AND NADPH Descriptor: 6-O-phosphono-beta-D-glucopyranose, CALCIUM ION, GLUCOSE 6-PHOSPHATE 1-DEHYDROGENASE, ... Authors: Adams, M.J, Cosgrove, M.S, Gover, S. Deposit date: 2000-09-12 Release date: 2000-12-11 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.48 Å) Cite: An Examination of the Role of Asp-177 in the His-Asp Catalytic Dyad of Leuconostoc Mesenteroides Glucose 6-Phosphate Dehydrogenase: X-Ray Structure and Ph Dependence of Kinetic Parameters of the D177N Mutant Enzyme Biochemistry, 39, 2000
1H93	ACTIVE MUTANT (S215->C) OF GLUCOSE 6-PHOSPHATE DEHYDROGENASE FROM LEUCONOSTOC MESENTEROIDES Descriptor: CALCIUM ION, GLUCOSE 6-PHOSPHATE 1-DEHYDROGENASE, GLYCEROL Authors: Adams, M.J, Naylor, C.E, Gover, S. Deposit date: 2001-02-23 Release date: 2001-05-03 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Nadp+ and Nad+ Binding to the Dual Coenzyme Specific Enzyme Leuconostoc Mesenteroides Glucose 6-Phosphate Dehydrogenase: Different Interdomain Hinge Angles are Seen in Different Binary and Ternary Complexes Acta Crystallogr.,Sect.D, 57, 2001
1H94	COMPLEX OF ACTIVE MUTANT (S215->C) OF GLUCOSE 6-PHOSPHATE DEHYDROGENASE FROM L.MESENTEROIDES WITH COENZYME NAD Descriptor: GLUCOSE 6-PHOSPHATE 1-DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Adams, M.J, Naylor, C.E, Gover, S. Deposit date: 2001-02-23 Release date: 2001-05-03 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Nadp+ and Nad+ Binding to the Dual Coenzyme Specific Enzyme Leuconostoc Mesenteroides Glucose 6-Phosphate Dehydrogenase: Different Interdomain Hinge Angles are Seen in Different Binary and Ternary Complexes Acta Crystallogr.,Sect.D, 57, 2001
1H9A	COMPLEX OF ACTIVE MUTANT (Q365->C) OF GLUCOSE 6-PHOSPHATE DEHYDROGENASE FROM L. MESENTEROIDES WITH COENZYME NADP Descriptor: GLUCOSE 6-PHOSPHATE 1-DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION Authors: Adams, M.J, Naylor, C.E, Gover, S. Deposit date: 2001-03-06 Release date: 2001-05-03 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.16 Å) Cite: Nadp+ and Nad+ Binding to the Dual Coenzyme Specific Enzyme Leuconostoc Mesenteroides Glucose 6-Phosphate Dehydrogenase: Different Interdomain Hinge Angles are Seen in Different Binary and Ternary Complexes Acta Crystallogr.,Sect.D, 57, 2001
1H9B	ACTIVE MUTANT (Q365->C) OF GLUCOSE 6-PHOSPHATE DEHYDROGENASE FROM LEUCONOSTOC MESENTEROIDES Descriptor: GLUCOSE 6-PHOSPHATE 1-DEHYDROGENASE, SULFATE ION Authors: Adams, M.J, Naylor, C.E, Gover, S. Deposit date: 2001-03-06 Release date: 2001-05-03 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Nadp+ and Nad+ Binding to the Dual Coenzyme Specific Enzyme Leuconostoc Mesenteroides Glucose 6-Phosphate Dehydrogenase: Different Interdomain Hinge Angles are Seen in Different Binary and Ternary Complexes Acta Crystallogr.,Sect.D, 57, 2001
1QKI	X-RAY STRUCTURE OF HUMAN GLUCOSE 6-PHOSPHATE DEHYDROGENASE (VARIANT CANTON R459L) COMPLEXED WITH STRUCTURAL NADP+ Descriptor: GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE, GLYCEROL, GLYCOLIC ACID, ... Authors: Au, S.W.N, Gover, S, Lam, V.M.S, Adams, M.J. Deposit date: 1999-07-20 Release date: 2000-03-16 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (3 Å) Cite: Human Glucose-6-Phosphate Dehydrogenase: The Crystal Structure Reveals a Structural Nadp+ Molecule and Provides Insights Into Enzyme Deficiency Structure, 8, 2000
2BH9	X-RAY STRUCTURE OF A DELETION VARIANT OF HUMAN GLUCOSE 6-PHOSPHATE DEHYDROGENASE COMPLEXED WITH STRUCTURAL AND COENZYME NADP Descriptor: GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Gover, S, Vandeputte-Rutten, L, Au, S.W.N, Adams, M.J. Deposit date: 2005-01-08 Release date: 2005-04-25 Last modified: 2019-05-08 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural Studies of Glucose-6-Phosphate and Nadp+ Binding to Human Glucose-6-Phosphate Dehydrogenase Acta Crystallogr.,Sect.D, 61, 2005
2BHL	X-RAY STRUCTURE OF HUMAN GLUCOSE-6-PHOSPHATE DEHYDROGENASE (DELETION VARIANT) COMPLEXED WITH GLUCOSE-6-PHOSPHATE Descriptor: 6-O-phosphono-beta-D-glucopyranose, GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE, GLYCEROL Authors: Kotaka, M, Gover, S, Lam, V.M.S, Adams, M.J. Deposit date: 2005-01-13 Release date: 2005-04-25 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural Studies of Glucose-6-Phosphate and Nadp+ Binding to Human Glucose-6-Phosphate Dehydrogenase Acta Crystallogr.,Sect.D, 61, 2005
2DPG	COMPLEX OF INACTIVE MUTANT (H240->N) OF GLUCOSE 6-PHOSPHATE DEHYDROGENASE FROM LEUCONOSTOC MESENTEROIDES WITH NADP+ Descriptor: GLUCOSE 6-PHOSPHATE DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Adams, M.J, Naylor, C.E, Paludin, S, Gover, S. Deposit date: 1998-04-17 Release date: 1998-07-15 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.5 Å) Cite: On the mechanism of the reaction catalyzed by glucose 6-phosphate dehydrogenase. Biochemistry, 37, 1998
4LGV	X-ray crystal structure of Glucose-6-phosphate 1-dehydrogenase from Mycobacterium avium Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2013-06-28 Release date: 2013-07-24 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
5AQ1	Trypanosoma cruzi Glucose-6-phosphate Dehydrogenase in complex with G6P and NADPH Descriptor: 6-O-phosphono-beta-D-glucopyranose, GLUCOSE-6-PHOSPHATE DEHYDROGENASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Mercaldi, G.F, Dawson, A, Hunter, W.N, Cordeiro, A.T. Deposit date: 2015-09-18 Release date: 2016-07-20 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.65 Å) Cite: The Structure of a Trypanosoma Cruzi Glucose-6-Phosphate Dehydrogenase Reveals Differences from the Mammalian Enzyme. FEBS Lett., 590, 2016
5UKW	Crystal structure of human Glucose 6-phosphate Dehydrogenase mutant (A277C) complexed with G6P Descriptor: 6-O-phosphono-beta-D-glucopyranose, GLYCEROL, Glucose-6-phosphate 1-dehydrogenase Authors: Ranzani, A.T, Cordeiro, A.T. Deposit date: 2017-01-23 Release date: 2017-04-19 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Mutations in the tetramer interface of human glucose-6-phosphate dehydrogenase reveals kinetic differences between oligomeric states. FEBS Lett., 591, 2017
6D23	GLUCOSE-6-P DEHYDROGENASE (APO FORM) FROM TRYPANOSOMA CRUZI Descriptor: CHLORIDE ION, GLYCEROL, Glucose-6-phosphate 1-dehydrogenase, ... Authors: Botti, H, Ortiz, C, Comini, M.A, Larrieux, N, Buschiazzo, A. Deposit date: 2018-04-12 Release date: 2018-05-02 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Glucose-6-Phosphate Dehydrogenase from the Human Pathogen Trypanosoma cruzi Evolved Unique Structural Features to Support Efficient Product Formation. J.Mol.Biol., 431, 2019
6D24	Trypanosoma cruzi Glucose-6-P Dehydrogenase in complex with G6P Descriptor: 6-O-phosphono-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... Authors: Botti, H, Ortiz, C, Comini, M.A, Larrieux, N, Buschiazzo, A. Deposit date: 2018-04-12 Release date: 2018-05-02 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (3.35 Å) Cite: Glucose-6-Phosphate Dehydrogenase from the Human Pathogen Trypanosoma cruzi Evolved Unique Structural Features to Support Efficient Product Formation. J.Mol.Biol., 431, 2019
6E07	Crystal structure of Canton G6PD in complex with structural NADP Descriptor: GLYCEROL, Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: Rahighi, S, Mochly-Rosen, D, Wakatsuki, S. Deposit date: 2018-07-06 Release date: 2018-07-25 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Correcting glucose-6-phosphate dehydrogenase deficiency with a small-molecule activator. Nat Commun, 9, 2018
6E08	Crystal structure of G6PD in complex with structural NADP Descriptor: GLYCEROL, Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Rahighi, S, Mochly Rosen, D, Wakatsuki, S. Deposit date: 2018-07-06 Release date: 2018-07-25 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Correcting glucose-6-phosphate dehydrogenase deficiency with a small-molecule activator. Nat Commun, 9, 2018
6JYU	Crystal structure of Human G6PD Canton Descriptor: Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Au, S.W.N. Deposit date: 2019-04-28 Release date: 2020-04-29 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Crystal structure of Human G6PD Canton To Be Published
6VA0	Crystal structure of glucose-6-phosphate dehydrogenase W509A mutant in complex with catalytic NADP+ Descriptor: Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Horikoshi, N, Mochly-Rosen, D, Wakatsuki, S. Deposit date: 2019-12-16 Release date: 2021-01-27 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Long-range structural defects by pathogenic mutations in most severe glucose-6-phosphate dehydrogenase deficiency. Proc.Natl.Acad.Sci.USA, 118, 2021
6VA7	Crystal structure of glucose-6-phosphate dehydrogenase P396L mutant in complex with catalytic NADP+ Descriptor: Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Horikoshi, N, Mochly-Rosen, D, Wakatsuki, S. Deposit date: 2019-12-17 Release date: 2021-01-27 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.07 Å) Cite: Long-range structural defects by pathogenic mutations in most severe glucose-6-phosphate dehydrogenase deficiency. Proc.Natl.Acad.Sci.USA, 118, 2021
6VA8	Crystal structure of glucose-6-phosphate dehydrogenase F381L mutant in complex with catalytic NADP+ Descriptor: Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Horikoshi, N, Mochly-Rosen, D, Wakatsuki, S. Deposit date: 2019-12-17 Release date: 2021-01-27 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.95 Å) Cite: Long-range structural defects by pathogenic mutations in most severe glucose-6-phosphate dehydrogenase deficiency. Proc.Natl.Acad.Sci.USA, 118, 2021
6VA9	Crystal structure of glucose-6-phosphate dehydrogenase R393H mutant in complex with catalytic NADP+ Descriptor: Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Horikoshi, N, Mochly-Rosen, D, Wakatsuki, S. Deposit date: 2019-12-17 Release date: 2021-01-27 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.95 Å) Cite: Long-range structural defects by pathogenic mutations in most severe glucose-6-phosphate dehydrogenase deficiency. Proc.Natl.Acad.Sci.USA, 118, 2021
6VAQ	Crystal structure of glucose-6-phosphate dehydrogenase V394L mutant in complex with catalytic NADP+ Descriptor: Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Horikoshi, N, Mochly-Rosen, D, Wakatsuki, S. Deposit date: 2019-12-17 Release date: 2021-01-27 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Long-range structural defects by pathogenic mutations in most severe glucose-6-phosphate dehydrogenase deficiency. Proc.Natl.Acad.Sci.USA, 118, 2021

 

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