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7OJ5
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BU of 7oj5 by Molmil
Cryo-EM structure of Medicago truncatula HISN5 protein
Descriptor: Imidazoleglycerol-phosphate dehydratase, MANGANESE (II) ION
Authors:Ruszkowski, M, Witek, W.
Deposit date:2021-05-13
Release date:2021-06-02
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Cryo-EM and crystal structures of a herbicide development target, HISN5
To Be Published
2F1D
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BU of 2f1d by Molmil
X-Ray Structure of imidazoleglycerol-phosphate dehydratase
Descriptor: Imidazoleglycerol-phosphate dehydratase 1, MANGANESE (II) ION, SULFATE ION
Authors:Rice, D.W, Glynn, S.E, Baker, P.J, Sedelnikova, S.E, Davies, C.L, Eadsforth, T.C.
Deposit date:2005-11-14
Release date:2006-01-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure and mechanism of imidazoleglycerol-phosphate dehydratase.
Structure, 13, 2005
6FWH
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BU of 6fwh by Molmil
Acanthamoeba IGPD in complex with R-C348 to 1.7A resolution
Descriptor: Imidazoleglycerol-phosphate dehydratase, MAGNESIUM ION, MANGANESE (II) ION, ...
Authors:Roberts, C.W, Bisson, C, Baker, P.J.
Deposit date:2018-03-06
Release date:2018-07-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structural and functional studies of histidine biosynthesis in Acanthamoeba spp. demonstrates a novel molecular arrangement and target for antimicrobials.
PLoS ONE, 13, 2018
6KHH
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BU of 6khh by Molmil
Crystal Structure of HisB from Mycobacterium tuberculosis
Descriptor: ACETAMIDE, CHLORIDE ION, Imidazoleglycerol-phosphate dehydratase, ...
Authors:Kumar, D, Jha, B, Pal, R.K, Biswal, B.K.
Deposit date:2019-07-15
Release date:2020-07-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Characterization of a triazole scaffold compound as an inhibitor of Mycobacterium tuberculosis imidazoleglycerol-phosphate dehydratase.
Proteins, 2021
2AE8
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BU of 2ae8 by Molmil
Crystal Structure of Imidazoleglycerol-phosphate Dehydratase from Staphylococcus aureus subsp. aureus N315
Descriptor: Imidazoleglycerol-phosphate dehydratase, MAGNESIUM ION
Authors:Kim, Y, Quartey, P, Holzle, D, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2005-07-21
Release date:2005-09-06
Last modified:2015-05-20
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Crystal Structure of Imidazoleglycerol-phosphate Dehydratase from Staphylococcus aureus subsp. aureus N315
To be Published
4GQU
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BU of 4gqu by Molmil
Crystal structure of HisB from Mycobacterium tuberculosis
Descriptor: 1,2-ETHANEDIOL, Imidazoleglycerol-phosphate dehydratase, MANGANESE (II) ION
Authors:Ahangar, M.S, Vyas, R, Nasir, N, Biswal, B.K.
Deposit date:2012-08-24
Release date:2013-08-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Crystal structures of the native, substrate- bound and inhibited forms of Mycobacterium tuberculosis imidazole glycerol phosphate dehydratase
Acta Crystallogr.,Sect.D, 2013
6YJH
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BU of 6yjh by Molmil
Crystal structure of Imidazole Glycerol Phosphate Dehydratase from Mycobacterium tuberculosis at 1.61 A resolution
Descriptor: Imidazoleglycerol-phosphate dehydratase, MANGANESE (II) ION
Authors:Timofeev, V.I, Abramchik, Y.A, Skvortsov, T.A, Azhikina, T.L, Muravieva, T.I, Kostromina, M.A, Esipov, R.S, Kuranova, I.P.
Deposit date:2020-04-03
Release date:2021-04-14
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Crystal structure of Imidazole Glycerol Phosphate Dehydratase from Mycobacterium tuberculosis at 1.61 A resolution
To Be Published
1RHY
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BU of 1rhy by Molmil
Crystal structure of Imidazole Glycerol Phosphate Dehydratase
Descriptor: ACETIC ACID, ETHYL MERCURY ION, GLYCEROL, ...
Authors:Sinha, S.C, Chaudhuri, B.N, Burgner, J.W, Yakovleva, G, Davisson, V.J, Smith, J.L.
Deposit date:2003-11-14
Release date:2004-05-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of imidazole glycerol-phosphate dehydratase: duplication of an unusual fold
J.Biol.Chem., 279, 2004
4QNJ
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BU of 4qnj by Molmil
The structure of wt A. thaliana IGPD2 in complex with Mn2+ and formate at 1.3A resolution
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, FORMIC ACID, ...
Authors:Bisson, C, Britton, K.L, Sedelnikova, S.E, Rodgers, H.F, Eadsforth, T.C, Viner, R, Hawkes, T.R, Baker, P.J, Rice, D.W.
Deposit date:2014-06-18
Release date:2015-06-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
Structure, 23, 2015
4QNK
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BU of 4qnk by Molmil
The structure of wt A. thaliana IGPD2 in complex with Mn2+ and phosphate
Descriptor: 1,2-ETHANEDIOL, Imidazoleglycerol-phosphate dehydratase 2, chloroplastic, ...
Authors:Bisson, C, Britton, K.L, Sedelnikova, S.E, Rodgers, H.F, Eadsforth, T.C, Viner, R, Hawkes, T.R, Baker, P.J, Rice, D.W.
Deposit date:2014-06-18
Release date:2015-06-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
Structure, 23, 2015
5XDS
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BU of 5xds by Molmil
Crystal structure of Mycobacterium tuberculosis HisB bound with an inhibitor
Descriptor: (2S)-2-azanyl-3-(4H-1,2,4-triazol-3-yl)propanoic acid, CHLORIDE ION, Imidazoleglycerol-phosphate dehydratase, ...
Authors:Kumar, D, Jha, B, Ahangar, M.S, Kumar, B.B.
Deposit date:2017-03-29
Release date:2018-04-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Characterization of a triazole scaffold compound as an inhibitor of Mycobacterium tuberculosis imidazoleglycerol-phosphate dehydratase.
Proteins, 2021
6EZM
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BU of 6ezm by Molmil
Imidazoleglycerol-phosphate dehydratase from Saccharomyces cerevisiae
Descriptor: Imidazoleglycerol-phosphate dehydratase, MANGANESE (II) ION, [(2R)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl]phosphonic acid
Authors:Rawson, S, Bisson, C, Hurdiss, D.L, Muench, S.P.
Deposit date:2017-11-15
Release date:2018-02-07
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Elucidating the structural basis for differing enzyme inhibitor potency by cryo-EM.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6EZJ
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BU of 6ezj by Molmil
Imidazoleglycerol-phosphate dehydratase
Descriptor: Imidazoleglycerol-phosphate dehydratase 2, chloroplastic, MANGANESE (II) ION, ...
Authors:Rawson, S, Bisson, C, Hurdiss, D.L, Muench, S.P.
Deposit date:2017-11-15
Release date:2018-02-07
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Elucidating the structural basis for differing enzyme inhibitor potency by cryo-EM.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5ZQN
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BU of 5zqn by Molmil
Crystal structure of Mycobacterium tuberculosis HisB in complex with a ligand
Descriptor: (2R,3S)-2,3-dihydroxy-3-(1H-imidazol-5-yl)propyl dihydrogen phosphate, CHLORIDE ION, Imidazoleglycerol-phosphate dehydratase, ...
Authors:Kumar, D, Pal, R.K, Biswal, B.K.
Deposit date:2018-04-19
Release date:2018-05-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Characterization of a triazole scaffold compound as an inhibitor of Mycobacterium tuberculosis imidazoleglycerol-phosphate dehydratase.
Proteins, 2021
7DDV
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BU of 7ddv by Molmil
Crystal structure of M.tuberculosis imidazole glycerol phosphate dehydratase in complex with an inhibitor
Descriptor: (1S)-1-(2-methyl-1,2,4-triazol-3-yl)ethanamine, CHLORIDE ION, GLYCEROL, ...
Authors:Tiwari, S, Pal, R.K, Biswal, B.K.
Deposit date:2020-10-29
Release date:2021-11-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of M.tuberculosis imidazole glycerol phosphate dehydratase in complex with an inhibitor
To Be Published
7DNQ
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BU of 7dnq by Molmil
Crystal structure of M.tuberculosis imidazole glycerol phosphate dehydratase in complex with an inhibitor
Descriptor: 1,2-ETHANEDIOL, 2-(1H-1,2,4-triazol-5-ylsulfanyl)ethanamine, CHLORIDE ION, ...
Authors:Tiwari, S, Pal, R.K, Biswal, B.K.
Deposit date:2020-12-10
Release date:2021-12-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal structure of M.tuberculosis imidazole glycerol phosphate dehydratase in complex with an inhibitor
To Be Published
7FCY
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BU of 7fcy by Molmil
Crystal structure of M.tuberculosis imidazole glycerol phosphate dehydratase in complex with an inhibitor
Descriptor: (1S)-2-methyl-1-(2-methyl-1,2,4-triazol-3-yl)propan-1-amine, 1,2-ETHANEDIOL, ACETATE ION, ...
Authors:Tiwari, S, Pal, R.K, Biswal, B.K.
Deposit date:2021-07-15
Release date:2022-07-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.848 Å)
Cite:Crystal structure of M.tuberculosis imidazole glycerol phosphate dehydratase in complex with an inhibitor
To Be Published
4MU4
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BU of 4mu4 by Molmil
The form B structure of an E21Q catalytic mutant of A. thaliana IGPD2 in complex with Mn2+ and its substrate, 2R3S-IGP, to 1.41 A resolution
Descriptor: (2R,3S)-2,3-dihydroxy-3-(1H-imidazol-5-yl)propyl dihydrogen phosphate, 1,2-ETHANEDIOL, Imidazoleglycerol-phosphate dehydratase 2, ...
Authors:Bisson, C, Britton, K.L, Sedelnikova, S.E, Baker, P.J, Rice, D.W.
Deposit date:2013-09-20
Release date:2014-09-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
Structure, 23, 2015
4MU0
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BU of 4mu0 by Molmil
The structure of wt A. thaliana IGPD2 in complex with Mn2+ and 1,2,4-triazole at 1.3 A resolution
Descriptor: 1,2,4-TRIAZOLE, 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Bisson, C, Britton, K.L, Sedelnikova, S.E, Baker, P.J, Rice, D.W.
Deposit date:2013-09-20
Release date:2014-09-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
Structure, 23, 2015
4MU3
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BU of 4mu3 by Molmil
The form A structure of an E21Q catalytic mutant of A. thaliana IGPD2 in complex with Mn2+ and a mixture of its substrate, 2R3S-IGP, and an inhibitor, 2S3S-IGP, to 1.12 A resolution
Descriptor: (2R,3S)-2,3-dihydroxy-3-(1H-imidazol-5-yl)propyl dihydrogen phosphate, (2S,3S)-2,3-dihydroxy-3-(1H-imidazol-5-yl)propyl dihydrogen phosphate, 1,2-ETHANEDIOL, ...
Authors:Bisson, C, Britton, K.L, Sedelnikova, S.E, Baker, P.J, Rice, D.W.
Deposit date:2013-09-20
Release date:2014-09-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
Structure, 23, 2015
4MU1
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BU of 4mu1 by Molmil
The structure of wt A. thaliana IGPD2 in complex with Mn2+, imidazole, and sulfate at 1.5 A resolution
Descriptor: 1,2-ETHANEDIOL, IMIDAZOLE, Imidazoleglycerol-phosphate dehydratase 2, ...
Authors:Bisson, C, Britton, K.L, Sedelnikova, S.E, Baker, P.J, Rice, D.W.
Deposit date:2013-09-20
Release date:2014-09-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
Structure, 23, 2015
5DNL
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BU of 5dnl by Molmil
Crystal structure of IGPD from Pyrococcus furiosus in complex with (S)-C348
Descriptor: Imidazoleglycerol-phosphate dehydratase, MANGANESE (II) ION, [(2S)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl]phosphonic acid
Authors:Bisson, C, Britton, K.L, Sedelnikova, S.E, Rodgers, H.F, Eadsforth, T.C, Viner, R.C, Hawkes, T.R, Baker, P.J, Rice, D.W.
Deposit date:2015-09-10
Release date:2016-09-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Mirror-Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide.
Angew.Chem.Int.Ed.Engl., 55, 2016
5DNX
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BU of 5dnx by Molmil
Crystal structure of IGPD from Pyrococcus furiosus in complex with (R)-C348
Descriptor: Imidazoleglycerol-phosphate dehydratase, MANGANESE (II) ION, [(2R)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl]phosphonic acid
Authors:Bisson, C, Britton, K.L, Sedelnikova, S.E, Rodgers, H.F, Eadsforth, T.C, Viner, R.C, Hawkes, T.R, Baker, P.J, Rice, D.W.
Deposit date:2015-09-10
Release date:2016-10-05
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mirror-Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide.
Angew.Chem.Int.Ed.Engl., 55, 2016
5EKW
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BU of 5ekw by Molmil
A. thaliana IGPD2 in complex with the racemate of the triazole-phosphonate inhibitor, C348
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
Authors:Bisson, C, Britton, K.L, Sedelnikova, S.E, Rodgers, H.F, Eadsforth, T.C, Viner, R.C, Hawkes, T.R, Baker, P.J, Rice, D.W.
Deposit date:2015-11-04
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Mirror-Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide.
Angew.Chem.Int.Ed.Engl., 55, 2016
5EL9
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BU of 5el9 by Molmil
A. thaliana IGPD2 in complex with the triazole-phosphonate inhibitor, (S)-C348, to 1.1A resolution
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Imidazoleglycerol-phosphate dehydratase 2, ...
Authors:Bisson, C, Britton, K.L, Sedelnikova, S.E, Rodgers, H.F, Eadsforth, T.C, Viner, R.C, Hawkes, T.R, Baker, P.J, Rice, D.W.
Deposit date:2015-11-04
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Mirror-Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide.
Angew.Chem.Int.Ed.Engl., 55, 2016

 

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