8F2P
 
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8D9W
 | | beta-Arf1 homodimeric interface within AP-1, Arf1, Nef, MHC-I lattice on narrow tubes | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.H, Hurley, J.H. | | Deposit date: | 2022-06-11 | | Release date: | 2023-07-05 | | Method: | ELECTRON MICROSCOPY (9.3 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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8D9V
 | | gamma-Arf1 homodimeric interface within AP-1, Arf1, Nef lattice on narrow membrane tubes | | Descriptor: | ADP ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-06-11 | | Release date: | 2022-11-09 | | Method: | ELECTRON MICROSCOPY (9.4 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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8D9U
 | | AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes, centered on beta-Arf1 | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-06-11 | | Release date: | 2022-11-09 | | Last modified: | 2022-12-21 | | Method: | ELECTRON MICROSCOPY (20 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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8D9T
 | | AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes, centered on gamma-Arf1 | | Descriptor: | ADP ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-06-11 | | Release date: | 2022-11-09 | | Last modified: | 2022-12-21 | | Method: | ELECTRON MICROSCOPY (20 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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8D9S
 | | AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated wide membrane tubes, centered on beta-Arf1 | | Descriptor: | ADP ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-06-11 | | Release date: | 2022-11-09 | | Last modified: | 2022-12-21 | | Method: | ELECTRON MICROSCOPY (20 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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8D9R
 | | AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated wide membrane tubes, centered on gamma-Arf1 | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-06-11 | | Release date: | 2022-11-09 | | Last modified: | 2022-12-21 | | Method: | ELECTRON MICROSCOPY (20 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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8D4G
 | | gamma-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated wide(r) membrane tubes | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-06-01 | | Release date: | 2023-06-14 | | Method: | ELECTRON MICROSCOPY (11.6 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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8D4F
 | | beta-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated wide(r) membrane tubes | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-06-01 | | Release date: | 2023-06-14 | | Method: | ELECTRON MICROSCOPY (9.8 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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8D4E
 | | Asymmetric unit of AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated wide(r) membrane tubes | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-06-01 | | Release date: | 2023-06-14 | | Method: | ELECTRON MICROSCOPY (9.2 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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8D4D
 | | gamma-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated narrow membrane tubes | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-06-01 | | Release date: | 2023-06-14 | | Method: | ELECTRON MICROSCOPY (9.6 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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8D4C
 | | beta-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated narrow membrane tubes | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-06-01 | | Release date: | 2023-06-14 | | Method: | ELECTRON MICROSCOPY (9.3 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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7UX3
 | | Asymmetric unit of AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-05-04 | | Release date: | 2023-05-10 | | Last modified: | 2023-06-14 | | Method: | ELECTRON MICROSCOPY (9.6 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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7D7S
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6URI
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6OWT
 | | Structure of SIVsmm Nef and SMM tetherin bound to the clathrin adaptor AP-2 complex | | Descriptor: | AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit sigma, ... | | Authors: | Buffalo, C.Z, Ren, X, Hurley, J.H. | | Deposit date: | 2019-05-10 | | Release date: | 2019-09-25 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural Basis for Tetherin Antagonism as a Barrier to Zoonotic Lentiviral Transmission.
Cell Host Microbe, 26, 2019
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6K6N
 | | Crystal structure of SIVmac239 Nef protein | | Descriptor: | Protein Nef | | Authors: | Hirao, K, Andrews, S, Kuroki, K, Kusaka, H, Tadokoro, T, Kita, S, Ose, T, Rowland-Jones, S, Maenaka, K. | | Deposit date: | 2019-06-04 | | Release date: | 2020-03-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.0002 Å) | | Cite: | Structure of HIV-2 Nef Reveals Features Distinct from HIV-1 Involved in Immune Regulation.
Iscience, 23, 2020
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6DFF
 | | Structure of the cargo bound AP-1:Arf1:tetherin-Nef monomer | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Morris, K.L, Buffalo, C.Z, Ren, X, Hurley, J.H. | | Deposit date: | 2018-05-14 | | Release date: | 2018-08-08 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
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6D84
 | | Structure of the cargo bound AP-1:Arf1:tetherin-Nef (L164A, L165A) dileucine mutant dimer | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Buffalo, C.Z, Morris, K.L, Hurley, J.H. | | Deposit date: | 2018-04-25 | | Release date: | 2018-08-08 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (6.72 Å) | | Cite: | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
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6D83
 | | Structure of the cargo bound AP-1:Arf1:tetherin-Nef (L164A, L165A) dileucine mutant dimer monomeric subunit | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Buffalo, C.Z, Morris, K.L, Hurley, J.H. | | Deposit date: | 2018-04-25 | | Release date: | 2018-08-08 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (4.27 Å) | | Cite: | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
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6CRI
 | | Structure of the cargo bound AP-1:Arf1:tetherin-Nef stable closed trimer | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Morris, K.L, Buffalo, C.Z, Hurley, J.H. | | Deposit date: | 2018-03-18 | | Release date: | 2018-08-01 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (6.8 Å) | | Cite: | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
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6CM9
 | | Structure of the cargo bound AP-1:Arf1:tetherin-Nef closed trimer monomeric subunit | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Morris, K.L, Buffalo, C.Z, Ren, X, Hurley, J.H. | | Deposit date: | 2018-03-03 | | Release date: | 2018-08-08 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.73 Å) | | Cite: | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
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6B72
 | | A novel HIV-1 Nef dimer interface induced by a single octyl-glucoside molecule | | Descriptor: | Protein Nef, octyl beta-D-glucopyranoside | | Authors: | Wu, M, Augelli-Szafran, C.E, Ptak, R.G, Smithgall, T.E. | | Deposit date: | 2017-10-03 | | Release date: | 2018-02-21 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | A single beta-octyl glucoside molecule induces HIV-1 Nef dimer formation in the absence of partner protein binding.
PLoS ONE, 13, 2018
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5NUI
 | | Crystal structure of SIVmac239 Nef in an ExxxLM endocytic sorting motif bound state | | Descriptor: | Protein Nef, SER-GLN-ILE-LYS-ARG-LEU-LEU-SER | | Authors: | Manrique, S, Horenkamp, F.A, Anand, K, Geyer, M. | | Deposit date: | 2017-04-30 | | Release date: | 2017-08-16 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Endocytic sorting motif interactions involved in Nef-mediated downmodulation of CD4 and CD3.
Nat Commun, 8, 2017
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5NUH
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