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7QB0
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BU of 7qb0 by Molmil
Solution structure of paxillin LIM2/3
Descriptor: Isoform Alpha of Paxillin, ZINC ION
Authors:Prestel, A, Michaelis, M, Klishin, N, Moeller, H.M.
Deposit date:2021-11-17
Release date:2022-11-30
Method:SOLUTION NMR
Cite:A flexible loop in the paxillin LIM3 domain mediates direct binding to integrin beta3
To Be Published
7LT9
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BU of 7lt9 by Molmil
Crystal structure of Ras suppressor-1 in complex with PINCH-1 LIM4-5 domains
Descriptor: LIM and senescent cell antigen-like-containing domain protein 1, Ras suppressor protein 1, ZINC ION
Authors:Fukuda, K, Qin, J.
Deposit date:2021-02-19
Release date:2021-04-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.050112 Å)
Cite:Molecular basis for Ras suppressor-1 binding to PINCH-1 in focal adhesion assembly.
J.Biol.Chem., 296, 2021
7AOI
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BU of 7aoi by Molmil
Trypanosoma brucei mitochondrial ribosome large subunit assembly intermediate
Descriptor: 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L17, ...
Authors:Tobiasson, V, Gahura, O, Aibara, S, Baradaran, R, Zikova, A, Amunts, A.
Deposit date:2020-10-14
Release date:2020-12-02
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Interconnected assembly factors regulate the biogenesis of mitoribosomal large subunit.
Embo J., 40, 2021
7ANE
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BU of 7ane by Molmil
Leishmania Major mitochondrial ribosome
Descriptor: 30S Ribosomal protein S17-like protein, 50S ribosomal protein L13-like protein, AKAP7_NLS domain-containing protein, ...
Authors:Soufari, H, Waltz, F, Parrot, C, Bochler, A, Hashem, Y.
Deposit date:2020-10-11
Release date:2021-06-23
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis.
Proc.Natl.Acad.Sci.USA, 117, 2020
7AM2
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BU of 7am2 by Molmil
Intermediate assembly of the Large subunit from Leishmania major mitochondrial ribosome
Descriptor: 50S ribosomal protein L13-like protein, ADENOSINE-5'-TRIPHOSPHATE, Acyl carrier protein, ...
Authors:Soufari, H, Waltz, F, Parrot, C, Bochler, A, Hashem, Y.
Deposit date:2020-10-07
Release date:2021-04-28
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis.
Proc.Natl.Acad.Sci.USA, 117, 2020
7AIH
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BU of 7aih by Molmil
The Large subunit of the Kinetoplastid mitochondrial ribosome
Descriptor: 50S ribosomal protein L13-like protein, C2H2-type domain-containing protein, L51_S25_CI-B8 domain-containing protein, ...
Authors:Soufari, H, Waltz, F, Parrot, C, Bochler, A, Hashem, Y.
Deposit date:2020-09-27
Release date:2021-04-28
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis.
Proc.Natl.Acad.Sci.USA, 117, 2020
7D2T
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BU of 7d2t by Molmil
Crystal structure of Rsu1/PINCH1_LIM45C complex
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, LIM and senescent cell antigen-like-containing domain protein 1, ...
Authors:Yang, H, Wei, Z, Yu, C.
Deposit date:2020-09-17
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics.
Elife, 10, 2021
7D2S
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BU of 7d2s by Molmil
Crystal structure of Rsu1/PINCH1_LIM5C complex
Descriptor: GLYCEROL, LIM and senescent cell antigen-like-containing domain protein 1, Ras suppressor protein 1, ...
Authors:Yang, H, Wei, Z, Cong, Y.
Deposit date:2020-09-17
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.653 Å)
Cite:Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics.
Elife, 10, 2021
7D2U
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BU of 7d2u by Molmil
Crystal structure of Rsu1/PINCH1_LIM45C complex
Descriptor: GLYCEROL, LIM and senescent cell antigen-like-containing domain protein 1, MALONATE ION, ...
Authors:Yang, H, Wei, Z, Cong, Y.
Deposit date:2020-09-17
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics.
Elife, 10, 2021
6YXY
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BU of 6yxy by Molmil
State B of the Trypanosoma brucei mitoribosomal large subunit assembly intermediate
Descriptor: 12S ribosomal RNA, ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Jaskolowski, M, Ramrath, D.J.F, Bieri, P, Niemann, M, Mattei, S, Calderaro, S, Leibundgut, M.A, Horn, E.K, Boehringer, D, Schneider, A, Ban, N.
Deposit date:2020-05-04
Release date:2020-10-14
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis.
Mol.Cell, 79, 2020
6U4N
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BU of 6u4n by Molmil
Solution structure of paxillin LIM4 in complex with kindlin-2 F0
Descriptor: Fermitin family homolog 2, Paxillin, ZINC ION
Authors:Zhu, L, Qin, J.
Deposit date:2019-08-26
Release date:2019-10-23
Last modified:2019-12-18
Method:SOLUTION NMR
Cite:Structural Basis of Paxillin Recruitment by Kindlin-2 in Regulating Cell Adhesion.
Structure, 27, 2019
6U4M
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BU of 6u4m by Molmil
Solution structure of paxillin LIM4
Descriptor: Paxillin, ZINC ION
Authors:Zhu, L, Qin, J.
Deposit date:2019-08-26
Release date:2019-10-23
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural Basis of Paxillin Recruitment by Kindlin-2 in Regulating Cell Adhesion.
Structure, 27, 2019
6MIF
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BU of 6mif by Molmil
Lim5 domain of PINCH1 protein
Descriptor: LIM and senescent cell antigen-like-containing domain protein 1, ZINC ION
Authors:Qin, J, Vaynberg, J.
Deposit date:2018-09-19
Release date:2018-10-31
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Non-catalytic signaling by pseudokinase ILK for regulating cell adhesion.
Nat Commun, 9, 2018
6HIX
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BU of 6hix by Molmil
Cryo-EM structure of the Trypanosoma brucei mitochondrial ribosome - This entry contains the large mitoribosomal subunit
Descriptor: 12S rRNA, 50S ribosomal protein L13, putative, ...
Authors:Ramrath, D.J.F, Niemann, M, Leibundgut, M, Bieri, P, Prange, C, Horn, K, Leitner, A, Boehringer, D, Schneider, A, Ban, N.
Deposit date:2018-08-31
Release date:2018-09-26
Last modified:2019-02-06
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
Science, 362, 2018
6HIV
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BU of 6hiv by Molmil
Cryo-EM structure of the Trypanosoma brucei mitochondrial ribosome - This entry contains the complete mitoribosome
Descriptor: 12S rRNA, 50S ribosomal protein L13, putative, ...
Authors:Ramrath, D.J.F, Niemann, M, Leibundgut, M, Bieri, P, Prange, C, Horn, E.K, Leitner, A, Boerhringer, D, Schneider, A, Ban, N.
Deposit date:2018-08-31
Release date:2018-10-03
Last modified:2018-11-07
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
Science, 362, 2018
6CME
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BU of 6cme by Molmil
Structure of wild-type ISL2-LID in complex with LHX4-LIM1+2
Descriptor: LIM/homeobox protein Lhx4,Insulin gene enhancer protein ISL-2, ZINC ION
Authors:Stokes, P.H, Silva, A, Guss, J.M, Matthews, J.M.
Deposit date:2018-03-04
Release date:2019-04-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Mutation in a flexible linker modulates binding affinity for modular complexes.
Proteins, 87, 2019
2MIU
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BU of 2miu by Molmil
Structure of FHL2 LIM adaptor and its Interaction with Ski
Descriptor: Four and a half LIM domains protein 2, ZINC ION
Authors:Yang, Y, Sun, Y, Medrano, E.E, Tian, X, Weiss, M.A.
Deposit date:2013-12-20
Release date:2014-01-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure of FHL2 LIM adaptor and its Interaction with Ski
To be Published
2MBV
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BU of 2mbv by Molmil
LMO4-LIM2 in complex with DEAF1 (404-418)
Descriptor: Fusion protein of LIM domain transcription factor LMO4 (77-147) and DEAF1 (404-418), ZINC ION
Authors:Joseph, S, Matthews, J.M, Kwan, A.H.-Y, Mackay, J.P, Cubeddu, L, Foo, P.
Deposit date:2013-08-06
Release date:2014-08-20
Method:SOLUTION NMR
Cite:Structural characterisation of LIM-only protein 4 (LMO4) in complex with Deformed Epidermal Autoregulatory Factor-1 (DEAF1)
To be Published
4KFZ
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BU of 4kfz by Molmil
Crystal structure of LMO2 and anti-LMO2 VH complex
Descriptor: Anti-LMO2 VH, LMO-2, ZINC ION
Authors:Sewell, H, Tanaka, T, El Omari, K, Cruz-Migoni, A, Mancini, E.J, Fuentes-Fernandez, N, Chambers, J, Rabbitts, T.H.
Deposit date:2013-04-28
Release date:2014-01-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Conformational flexibility of the oncogenic protein LMO2 primes the formation of the multi-protein transcription complex.
Sci Rep, 4, 2014
4JCJ
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BU of 4jcj by Molmil
Crystal structure of Isl1 LIM domains with Ldb1 LIM-interaction domain
Descriptor: Insulin gene enhancer protein ISL-1,LIM domain-binding protein 1, ZINC ION
Authors:Gadd, M.S, Jacques, D.A, Guss, J.M, Matthews, J.M.
Deposit date:2013-02-21
Release date:2013-06-19
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:A structural basis for the regulation of the LIM-homeodomain protein islet 1 (Isl1) by intra- and intermolecular interactions.
J.Biol.Chem., 288, 2013
2YPA
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BU of 2ypa by Molmil
Structure of the SCL:E47:LMO2:LDB1 complex bound to DNA
Descriptor: EBOX FORWARD, EBOX REVERSE, LIM DOMAIN-BINDING PROTEIN 1, ...
Authors:El Omari, K, Hoosdally, S.J, Tuladhar, K, Karia, D, Ponsele, E, Platonova, O, Vyas, P, Patient, R, Porcher, C, Mancini, E.J.
Deposit date:2012-10-30
Release date:2013-07-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for Lmo2-Driven Recruitment of the Scl:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets.
Cell Rep., 4, 2013
4HI9
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BU of 4hi9 by Molmil
1.2 structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain collected at wavelength 0.91974
Descriptor: IODIDE ION, Integrin-linked protein kinase, LIM and senescent cell antigen-like-containing domain protein 1, ...
Authors:Stiegler, A.L, Jakoncic, J, Stojanoff, V, Chiswell, B.P, Calderwood, D.A, Boggon, T.J.
Deposit date:2012-10-11
Release date:2013-12-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.203 Å)
Cite:1.2 structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain collected at wavelength 0.91974
To be Published
4HI8
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BU of 4hi8 by Molmil
Structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain collected at high energy, wavelength 0.32800
Descriptor: Integrin-linked protein kinase, LIM and senescent cell antigen-like-containing domain protein 1, PHOSPHATE ION, ...
Authors:Stiegler, A.L, Jakoncic, J, Stojanoff, V, Chiswell, B.P, Calderwood, D.A, Boggon, T.J.
Deposit date:2012-10-11
Release date:2013-12-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.203 Å)
Cite:Structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain collected at high energy, wavelength 0.32800
To be Published
2LZU
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BU of 2lzu by Molmil
Solution structure of LIMD2
Descriptor: LIM domain-containing protein 2, ZINC ION
Authors:Talebzadeh Farooji, M, Peng, H, Rauscher, F.J, Borden, K.K.L, Osborne, M.J.
Deposit date:2012-10-10
Release date:2014-04-16
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution Structure of LIMD2
To be Published
2LXD
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BU of 2lxd by Molmil
Backbone 1H, 13C, and 15N Chemical Shift Assignments for LMO2(LIM2)-Ldb1(LID)
Descriptor: Rhombotin-2,LIM domain-binding protein 1, ZINC ION
Authors:Dastmalchi, S, Wilkinson-White, L, Kwan, A.H, Gamsjaeger, R, Mackay, J.P, Matthews, J.M.
Deposit date:2012-08-20
Release date:2012-09-12
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structure of a tethered Lmo2(LIM2) /Ldb1(LID) complex.
Protein Sci., 21, 2012

 

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