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1PGJ
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BU of 1pgj by Molmil
X-RAY STRUCTURE OF 6-PHOSPHOGLUCONATE DEHYDROGENASE FROM THE PROTOZOAN PARASITE T. BRUCEI
Descriptor: 6-PHOSPHOGLUCONATE DEHYDROGENASE, SULFATE ION
Authors:Dohnalek, J, Phillips, C, Gover, S, Barrett, M.P, Adams, M.J.
Deposit date:1998-03-16
Release date:1998-11-11
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:A 2.8 A resolution structure of 6-phosphogluconate dehydrogenase from the protozoan parasite Trypanosoma brucei: comparison with the sheep enzyme accounts for differences in activity with coenzyme and substrate analogues.
J.Mol.Biol., 282, 1998
1PGN
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CRYSTALLOGRAPHIC STUDY OF COENZYME, COENZYME ANALOGUE AND SUBSTRATE BINDING IN 6-PHOSPHOGLUCONATE DEHYDROGENASE: IMPLICATIONS FOR NADP SPECIFICITY AND THE ENZYME MECHANISM
Descriptor: 6-PHOSPHOGLUCONATE DEHYDROGENASE, NICOTINAMIDE 8-BROMO-ADENINE DINUCLEOTIDE PHOSPHATE, PYROPHOSPHATE 2-, ...
Authors:Adams, M.J, Phillips, C, Gover, S.
Deposit date:1994-07-18
Release date:1995-02-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystallographic study of coenzyme, coenzyme analogue and substrate binding in 6-phosphogluconate dehydrogenase: implications for NADP specificity and the enzyme mechanism.
Structure, 2, 1994
1PGO
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BU of 1pgo by Molmil
CRYSTALLOGRAPHIC STUDY OF COENZYME, COENZYME ANALOGUE AND SUBSTRATE BINDING IN 6-PHOSPHOGLUCONATE DEHYDROGENASE: IMPLICATIONS FOR NADP SPECIFICITY AND THE ENZYME MECHANISM
Descriptor: 6-PHOSPHOGLUCONATE DEHYDROGENASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION
Authors:Adams, M.J, Phillips, C, Gover, S.
Deposit date:1994-07-18
Release date:1995-02-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystallographic study of coenzyme, coenzyme analogue and substrate binding in 6-phosphogluconate dehydrogenase: implications for NADP specificity and the enzyme mechanism.
Structure, 2, 1994
1PGP
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BU of 1pgp by Molmil
CRYSTALLOGRAPHIC STUDY OF COENZYME, COENZYME ANALOGUE AND SUBSTRATE BINDING IN 6-PHOSPHOGLUCONATE DEHYDROGENASE: IMPLICATIONS FOR NADP SPECIFICITY AND THE ENZYME MECHANISM
Descriptor: 6-PHOSPHOGLUCONATE DEHYDROGENASE, 6-PHOSPHOGLUCONIC ACID, SULFATE ION
Authors:Adams, M.J, Phillips, C, Gover, S, Naylor, C.E.
Deposit date:1994-07-18
Release date:1995-02-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystallographic study of coenzyme, coenzyme analogue and substrate binding in 6-phosphogluconate dehydrogenase: implications for NADP specificity and the enzyme mechanism.
Structure, 2, 1994
1PGQ
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BU of 1pgq by Molmil
CRYSTALLOGRAPHIC STUDY OF COENZYME, COENZYME ANALOGUE AND SUBSTRATE BINDING IN 6-PHOSPHOGLUCONATE DEHYDROGENASE: IMPLICATIONS FOR NADP SPECIFICITY AND THE ENZYME MECHANISM
Descriptor: 6-PHOSPHOGLUCONATE DEHYDROGENASE, ADENOSINE-2'-MONOPHOSPHATE, SULFATE ION
Authors:Adams, M.J, Phillips, C, Gover, S.
Deposit date:1994-07-18
Release date:1995-02-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Crystallographic study of coenzyme, coenzyme analogue and substrate binding in 6-phosphogluconate dehydrogenase: implications for NADP specificity and the enzyme mechanism.
Structure, 2, 1994
2IYO
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BU of 2iyo by Molmil
Structural characterization of a bacterial 6PDH reveals aspects of specificity, mechanism and mode of inhibition
Descriptor: 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING, 6-PHOSPHOGLUCONIC ACID, ...
Authors:Sundaramoorthy, R, Iulek, J, Hunter, W.N.
Deposit date:2006-07-21
Release date:2007-01-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of a Bacterial 6-Phosphogluconate Dehydrogenase Reveal Aspects of Specificity, Mechanism and Mode of Inhibition by Analogues of High-Energy Reaction Intermediates.
FEBS J., 274, 2007
2IYP
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BU of 2iyp by Molmil
product rup
Descriptor: 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING, ADENOSINE-2'-5'-DIPHOSPHATE, ...
Authors:Sundaramoorthy, R, Iulek, J, Hunter, W.N.
Deposit date:2006-07-21
Release date:2007-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Crystal Structures of a Bacterial 6-Phosphogluconate Dehydrogenase Reveal Aspects of Specificity, Mechanism and Mode of Inhibition by Analogues of High-Energy Reaction Intermediates.
FEBS J., 274, 2007
2IZ0
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BU of 2iz0 by Molmil
PEX inhibitor-home data
Descriptor: 1,2-ETHANEDIOL, 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ...
Authors:Sundaramoorthy, R, Iulek, J, Hunter, W.N.
Deposit date:2006-07-23
Release date:2007-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structures of a Bacterial 6- Phosphogluconate Dehydrogenase Reveal Aspects of Specificity, Mechanism and Mode of Inhibition by Analogues of High-Energy Reaction Intermediates.
FEBS J., 274, 2007
2IZ1
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BU of 2iz1 by Molmil
6PDH complexed with PEX inhibitor synchrotron data
Descriptor: 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, 4-PHOSPHO-D-ERYTHRONOHYDROXAMIC ACID, ...
Authors:Sundaramoorthy, R, Iulek, J, Hunter, W.N.
Deposit date:2006-07-23
Release date:2007-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures of a Bacterial 6- Phosphogluconate Dehydrogenase Reveal Aspects of Specificity, Mechanism and Mode of Inhibition by Analogues of High-Energy Reaction Intermediates.
FEBS J., 274, 2007
2JKV
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BU of 2jkv by Molmil
Structure of human Phosphogluconate Dehydrogenase in complex with NADPH at 2.53A
Descriptor: 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING, CHLORIDE ION, ...
Authors:Pilka, E.S, Kavanagh, K.L, von Delft, F, Muniz, J.R.C, Murray, J, Picaud, S, Guo, K, Edwards, A, Arrowsmith, C.H, Weigelt, J, Bountra, C, Oppermann, U.
Deposit date:2008-09-01
Release date:2009-09-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.532 Å)
Cite:Structure of Human Phosphogluconate Dehydrogenase in Complex with Nadph at 2.53A
To be Published
2P4Q
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BU of 2p4q by Molmil
Crystal Structure Analysis of Gnd1 in Saccharomyces cerevisiae
Descriptor: 6-phosphogluconate dehydrogenase, decarboxylating 1, CITRATE ANION
Authors:He, W, Wang, Y, Liu, W, Zhou, C.Z.
Deposit date:2007-03-12
Release date:2007-07-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Crystal structure of Saccharomyces cerevisiae 6-phosphogluconate dehydrogenase Gnd1
Bmc Struct.Biol., 7, 2007
2PGD
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BU of 2pgd by Molmil
THE STRUCTURE OF 6-PHOSPHOGLUCONATE DEHYDROGENASE REFINED AT 2 ANGSTROMS RESOLUTION
Descriptor: 6-PHOSPHOGLUCONATE DEHYDROGENASE, SULFATE ION
Authors:Adams, M.J, Phillips, C, Gover, S.
Deposit date:1994-07-18
Release date:1995-02-27
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of 6-phosphogluconate dehydrogenase refined at 2.5 A resolution.
Acta Crystallogr.,Sect.B, 47, 1991
2W8Z
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BU of 2w8z by Molmil
Geobacillus stearothermophilus 6-phosphogluconate dehydrogenase with bound 6- phosphogluconate
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING, ...
Authors:Cameron, S, Hunter, W.N.
Deposit date:2009-01-20
Release date:2009-04-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Geobacillus Stearothermophilus 6-Phosphogluconate Dehydrogenase, Complexed with 6-Phosphogluconate.
Acta Crystallogr.,Sect.F, 65, 2009
2ZYA
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BU of 2zya by Molmil
Dimeric 6-phosphogluconate dehydrogenase complexed with 6-phosphogluconate
Descriptor: 6-PHOSPHOGLUCONIC ACID, 6-phosphogluconate dehydrogenase, decarboxylating
Authors:Chen, Y.-Y, Ko, T.-P, Lo, L.-P, Lin, C.-H, Wang, A.H.-J.
Deposit date:2009-01-19
Release date:2009-09-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism
J.Struct.Biol., 169, 2010
2ZYD
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BU of 2zyd by Molmil
Dimeric 6-phosphogluconate dehydrogenase complexed with glucose
Descriptor: 6-phosphogluconate dehydrogenase, decarboxylating, D-glucose
Authors:Chen, Y.-Y, Ko, T.-P, Lo, L.-P, Lin, C.-H, Wang, A.H.-J.
Deposit date:2009-01-19
Release date:2009-09-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism
J.Struct.Biol., 169, 2010
2ZYG
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BU of 2zyg by Molmil
Apo-form of dimeric 6-phosphogluconate dehydrogenase
Descriptor: 6-phosphogluconate dehydrogenase, decarboxylating
Authors:Chen, Y.-Y, Ko, T.-P, Lo, L.-P, Lin, C.-H, Wang, A.H.-J.
Deposit date:2009-01-21
Release date:2009-09-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism
J.Struct.Biol., 169, 2010
3FWN
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BU of 3fwn by Molmil
Dimeric 6-phosphogluconate dehydrogenase complexed with 6-phosphogluconate and 2'-monophosphoadenosine-5'-diphosphate
Descriptor: 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, 6-PHOSPHOGLUCONIC ACID, 6-phosphogluconate dehydrogenase, ...
Authors:Chen, Y.-Y, Ko, T.-P, Lo, L.-P, Lin, C.-H, Wang, A.H.-J.
Deposit date:2009-01-19
Release date:2009-09-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism
J.Struct.Biol., 169, 2010
4E21
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BU of 4e21 by Molmil
The crystal structure of 6-phosphogluconate dehydrogenase from Geobacter metallireducens
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 6-phosphogluconate dehydrogenase (Decarboxylating)
Authors:Zhang, Z, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Seidel, R, Villigas, G, Zencheck, W, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2012-03-07
Release date:2012-03-21
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:The crystal structure of 6-phosphogluconate dehydrogenase from Geobacter metallireducens
To be Published
4GWG
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Crystal Structure Analysis of 6-phosphogluconate dehydrogenase apo-form
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-phosphogluconate dehydrogenase, decarboxylating
Authors:He, C, Zhou, L, Zhang, L.
Deposit date:2012-09-03
Release date:2012-11-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.3907 Å)
Cite:Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth.
Cancer Cell, 22, 2012
4GWK
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BU of 4gwk by Molmil
Crystal structure of 6-phosphogluconate dehydrogenase complexed with 3-phosphoglyceric acid
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-PHOSPHOGLYCERIC ACID, 6-phosphogluconate dehydrogenase, ...
Authors:He, C, Zhou, L, Zhang, L.
Deposit date:2012-09-03
Release date:2012-11-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.534 Å)
Cite:Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth.
Cancer Cell, 22, 2012
5UQ9
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BU of 5uq9 by Molmil
Crystal structure of 6-phosphogluconate dehydrogenase with ((4R,5R)-5-(hydroxycarbamoyl)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl dihydrogen phosphate
Descriptor: 6-phosphogluconate dehydrogenase, decarboxylating, [(4R,5R)-5-(hydroxycarbamoyl)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl dihydrogen phosphate
Authors:Leonard, P.G.
Deposit date:2017-02-07
Release date:2018-08-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation.
Cell Rep, 26, 2019
6FQX
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BU of 6fqx by Molmil
Plasmodium falciparum 6-phosphogluconate dehydrogenase in its apo form, in complex with its cofactor NADP+ and in complex with its substrate 6-phosphogluconate
Descriptor: 2-(2-ETHOXYETHOXY)ETHANOL, 6-phosphogluconate dehydrogenase, decarboxylating, ...
Authors:Fritz-Wolf, K, Haeussler, K, Reichmann, M, Rahlfs, S, Becker, K.
Deposit date:2018-02-15
Release date:2018-08-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Characterization of Plasmodium falciparum 6-Phosphogluconate Dehydrogenase as an Antimalarial Drug Target.
J. Mol. Biol., 430, 2018
6FQY
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BU of 6fqy by Molmil
Plasmodium falciparum 6-phosphogluconate dehydrogenase in its apo form, in complex with its cofactor NADP+ and in complex with its substrate 6-phosphogluconate
Descriptor: 1,2-ETHANEDIOL, 6-phosphogluconate dehydrogenase, decarboxylating, ...
Authors:Fritz-Wolf, K, Haeussler, K, Reichmann, M, Rahlfs, S, Becker, K.
Deposit date:2018-02-15
Release date:2018-08-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Characterization of Plasmodium falciparum 6-Phosphogluconate Dehydrogenase as an Antimalarial Drug Target.
J. Mol. Biol., 430, 2018
6FQZ
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BU of 6fqz by Molmil
Plasmodium falciparum 6-phosphogluconate dehydrogenase in its apo form, in complex with its cofactor NADP+ and in complex with its substrate 6-phosphogluconate
Descriptor: 6-PHOSPHOGLUCONIC ACID, 6-phosphogluconate dehydrogenase, decarboxylating, ...
Authors:Fritz-Wolf, K, Haeussler, K, Reichmann, M, Rahlfs, S, Becker, K.
Deposit date:2018-02-15
Release date:2018-08-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Characterization of Plasmodium falciparum 6-Phosphogluconate Dehydrogenase as an Antimalarial Drug Target.
J. Mol. Biol., 430, 2018
6VPB
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A novel membrane-bound 6-phosphogluconate dehydrogenase from the acetic acid bacteria Gluconacetobacter diazotrophicus (Gd6PGD)
Descriptor: 6-phosphogluconate dehydrogenase, DI(HYDROXYETHYL)ETHER, ISOPROPYL ALCOHOL, ...
Authors:Rodriguez-Romero, A, Rodriguez-Hernandez, A.
Deposit date:2020-02-02
Release date:2020-07-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:The structure of a novel membrane-associated 6-phosphogluconate dehydrogenase from Gluconacetobacter diazotrophicus (Gd6PGD) reveals a subfamily of short-chain 6PGDs.
Febs J., 288, 2021

 

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