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7ZTH
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BU of 7zth by Molmil
Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the open conformation
Descriptor: DNA (48-MER), PLP-dependent aminotransferase family protein
Authors:Freda, I, Montemiglio, L.C, Tramonti, A, Contestabile, R, Vallone, B, Exertier, C, Savino, C, Chaves Sanjuan, A, Bolognesi, M.
Deposit date:2022-05-10
Release date:2023-07-05
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR.
Nucleic Acids Res., 51, 2023
7ZLA
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BU of 7zla by Molmil
Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the half-closed conformation
Descriptor: DNA (48-MER), PLP-dependent aminotransferase family protein
Authors:Freda, I, Montemiglio, L.C, Tramonti, A, Contestabile, R, Vallone, B, Savino, C, Exertier, C, Bolognesi, M, Chaves Sanjuan, A.
Deposit date:2022-04-14
Release date:2023-07-05
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (3.99 Å)
Cite:Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR.
Nucleic Acids Res., 51, 2023
7ZN5
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BU of 7zn5 by Molmil
Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the closed conformation, C2 symmetry.
Descriptor: DNA (48-MER), PLP-dependent aminotransferase family protein
Authors:Freda, I, Montemiglio, L.C, Tramonti, A, Contestabile, R, Vallone, B, Exertier, C, Savino, C, Chaves Sanjuan, A, Bolognesi, M.
Deposit date:2022-04-20
Release date:2023-07-05
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR.
Nucleic Acids Res., 51, 2023
7ZPA
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BU of 7zpa by Molmil
Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the closed conformation, C1 symmetry
Descriptor: DNA (48-MER), PLP-dependent aminotransferase family protein
Authors:Freda, I, Montemiglio, L.C, Tramonti, A, Contestabile, R, Vallone, B, Exertier, C, Savino, C, Chaves Sanjuan, A, Bolognesi, M.
Deposit date:2022-04-27
Release date:2023-07-05
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR.
Nucleic Acids Res., 51, 2023
7XP0
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Crystal structure of PmiR from Pseudomonas aeruginosa
Descriptor: Probable transcriptional regulator, SULFATE ION, ZINC ION
Authors:Zhang, Y.X, Liang, H.H, Gan, J.H.
Deposit date:2022-05-02
Release date:2023-04-12
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:PmiR senses 2-methylisocitrate levels to regulate bacterial virulence in Pseudomonas aeruginosa.
Sci Adv, 8, 2022
7XP1
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Crystal structure of PmiR from Pseudomonas aeruginosa
Descriptor: ALPHA-METHYLISOCITRIC ACID, GLYCEROL, Probable transcriptional regulator, ...
Authors:Zhang, Y.X, Liang, H.H, Gan, J.H.
Deposit date:2022-05-02
Release date:2023-04-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:PmiR senses 2-methylisocitrate levels to regulate bacterial virulence in Pseudomonas aeruginosa.
Sci Adv, 8, 2022
7WJG
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BU of 7wjg by Molmil
Streptococcus mutans BusR transcriptional factor
Descriptor: CITRIC ACID, Putative transcriptional regulator (GntR family)
Authors:Li, X, Liu, N.
Deposit date:2022-01-06
Release date:2023-01-11
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural study of transcriptional factor BusR
To Be Published
7U5Q
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Crystal structure of transcriptional regulator, GntR family, from Brucella melitensis
Descriptor: BROMIDE ION, Transcriptional regulator, GntR family protein, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-03-02
Release date:2022-03-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of transcriptional regulator, GntR family, from Brucella melitensis
To be Published
7OZ3
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BU of 7oz3 by Molmil
S. agalactiae BusR in complex with its busA-promotor DNA
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, GntR family transcriptional regulator, pBusA_for, ...
Authors:Bandera, A.M, Witte, G.
Deposit date:2021-06-25
Release date:2021-08-11
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (4.46 Å)
Cite:BusR senses bipartite DNA binding motifs by a unique molecular ruler architecture.
Nucleic Acids Res., 49, 2021
7B5Y
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S. agalactiae BusR in complex with its busAB-promotor DNA
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, BusR binding site in the busAB promotor. strand1, BusR binding site in the busAB promotor. strand2, ...
Authors:Bandera, A.M, Witte, G.
Deposit date:2020-12-07
Release date:2021-08-11
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:BusR senses bipartite DNA binding motifs by a unique molecular ruler architecture.
Nucleic Acids Res., 49, 2021
7B5T
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BU of 7b5t by Molmil
S. agalactiae BusR transcription factor
Descriptor: GntR family transcriptional regulator
Authors:Bandera, A.M, Witte, G.
Deposit date:2020-12-07
Release date:2021-08-11
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:BusR senses bipartite DNA binding motifs by a unique molecular ruler architecture.
Nucleic Acids Res., 49, 2021
6WG7
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BU of 6wg7 by Molmil
Coordinates of NanR dimer fitted in Hexameric NanR-DNA hetero-complex cryo-EM map
Descriptor: DNA (35-MER), HTH-type transcriptional repressor NanR
Authors:Hariprasad, V, Horne, C, Santosh, P, Amy, H, Emre, B, Rachel, N, Michael, G, Georg, R, Borries, D, Renwick, D.
Deposit date:2020-04-05
Release date:2021-03-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (8.3 Å)
Cite:Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism.
Nat Commun, 12, 2021
6WFQ
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BU of 6wfq by Molmil
NanR dimer-DNA hetero-complex
Descriptor: DNA (5'-D(P*GP*GP*TP*AP*TP*AP*AP*CP*AP*GP*GP*TP*AP*TP*A)-3'), DNA (5'-D(P*TP*AP*TP*AP*CP*CP*TP*GP*TP*TP*AP*TP*AP*CP*C)-3'), HTH-type transcriptional repressor NanR
Authors:Hariprasad, V, Horne, C, Santosh, P, Amy, H, Emre, B, Rachel, N, Michael, G, Georg, R, Borries, D, Renwick, D.
Deposit date:2020-04-03
Release date:2021-03-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism.
Nat Commun, 12, 2021
7C7E
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BU of 7c7e by Molmil
Crystal structure of C terminal domain of Escherichia coli DgoR
Descriptor: Putative DNA-binding transcriptional regulator, SULFATE ION, TRIETHYLENE GLYCOL, ...
Authors:Lin, W.
Deposit date:2020-05-25
Release date:2021-01-20
Method:X-RAY DIFFRACTION (2.047 Å)
Cite:Structural and Functional Analyses of the Transcription Repressor DgoR From Escherichia coli Reveal a Divalent Metal-Containing D-Galactonate Binding Pocket.
Front Microbiol, 11, 2020
6Z74
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BU of 6z74 by Molmil
Structure of the transcriptional repressor Atu1419 (VanR) in complex with a fortuitous citrate from agrobacterium fabrum
Descriptor: 1,2-ETHANEDIOL, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Morera, S, Vigouroux, V.
Deposit date:2020-05-29
Release date:2020-12-02
Last modified:2021-01-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Characterization of the first tetrameric transcription factor of the GntR superfamily with allosteric regulation from the bacterial pathogen Agrobacterium fabrum.
Nucleic Acids Res., 49, 2021
6ZAB
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BU of 6zab by Molmil
Structure of the transcriptional repressor Atu1419 (VanR) from agrobacterium fabrum in complex a palindromic DNA (P6422 space group)
Descriptor: 1,2-ETHANEDIOL, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Morera, S, Naretto, A, Vigouroux, A, Legrand, P.
Deposit date:2020-06-05
Release date:2020-12-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Characterization of the first tetrameric transcription factor of the GntR superfamily with allosteric regulation from the bacterial pathogen Agrobacterium fabrum.
Nucleic Acids Res., 49, 2021
6ZA7
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BU of 6za7 by Molmil
Structure of the apo transcriptional repressor Atu1419 (VanR) from agrobacterium fabrum
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, SULFATE ION, ...
Authors:Morera, S, Vigouroux, A, Legrand, P.
Deposit date:2020-06-04
Release date:2020-12-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Characterization of the first tetrameric transcription factor of the GntR superfamily with allosteric regulation from the bacterial pathogen Agrobacterium fabrum.
Nucleic Acids Res., 49, 2021
6ZA0
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BU of 6za0 by Molmil
Structure of the transcriptional repressor Atu1419 (VanR) in complex with a fortuitous citrate from agrobacterium fabrum (P21212 space group)
Descriptor: 1,2-ETHANEDIOL, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Morera, S, Vigouroux, A, Legrand, P.
Deposit date:2020-06-04
Release date:2020-12-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Characterization of the first tetrameric transcription factor of the GntR superfamily with allosteric regulation from the bacterial pathogen Agrobacterium fabrum.
Nucleic Acids Res., 49, 2021
6ZA3
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BU of 6za3 by Molmil
Structure of the transcriptional repressor Atu1419 (VanR) from agrobacterium fabrum in complex a palindromic DNA (C2221 space group)
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ...
Authors:Morera, S, Vigouroux, A, Legrand, P.
Deposit date:2020-06-04
Release date:2020-12-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Characterization of the first tetrameric transcription factor of the GntR superfamily with allosteric regulation from the bacterial pathogen Agrobacterium fabrum.
Nucleic Acids Res., 49, 2021
6ON4
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BU of 6on4 by Molmil
Crystal structure of the GntR-type sialoregulator NanR from Escherichia coli, in complex with sialic acid
Descriptor: HTH-type transcriptional repressor NanR, N-acetyl-beta-neuraminic acid, ZINC ION, ...
Authors:Horne, C.R, Panjikar, S, North, R.A, Dobson, R.C.J.
Deposit date:2019-04-19
Release date:2020-07-08
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Control of the Escherichia coli sialoregulon by transcriptional repressor NanR.
J. Bacteriol., 195, 2013
6SBS
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BU of 6sbs by Molmil
YtrA from Sulfolobus acidocaldarius, a GntR-family transcription factor
Descriptor: Regulatory protein
Authors:Lemmens, L, Valegard, K, Lindas, A.C, Peeters, E, Maes, D.
Deposit date:2019-07-22
Release date:2019-07-31
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:YtrASa, a GntR-Family Transcription Factor, Represses Two Genetic Loci Encoding Membrane Proteins inSulfolobus acidocaldarius.
Front Microbiol, 10, 2019
6EP3
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BU of 6ep3 by Molmil
Lar controls the expression of the Listeria monocytogenes agr system and mediates virulence.
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Lmo0651 protein, ...
Authors:Pinheiro, J, Lisboa, J, Carvalho, F, Carreaux, A, Santos, N, Cabral, J, Sousa, S, Cabanes, D.
Deposit date:2017-10-10
Release date:2018-07-25
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:MouR controls the expression of the Listeria monocytogenes Agr system and mediates virulence.
Nucleic Acids Res., 46, 2018
6AZ6
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BU of 6az6 by Molmil
Streptococcus agalactiae GntR
Descriptor: GntR family transcriptional regulator
Authors:Pellock, S.J, Redinbo, M.R.
Deposit date:2017-09-10
Release date:2017-12-20
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (1.909 Å)
Cite:Structural basis for the regulation of beta-glucuronidase expression by human gut Enterobacteriaceae.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5XGF
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BU of 5xgf by Molmil
The fatty acid-responsive FadR repressor of Vibrio alginolyticus
Descriptor: Fatty acid metabolism regulator protein, NICKEL (II) ION
Authors:Lin, Y, Li, D.F, Feng, Y.J.
Deposit date:2017-04-13
Release date:2017-05-31
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Snapshort of Vibrio FadR-ligand complex structure reveals a new mechanism for bacterial fatty acid sensing
To Be Published
5KVR
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BU of 5kvr by Molmil
X-Ray Crystal Structure of a Fragment (1-75) of a Transcriptional Regulator PdhR from Escherichia coli CFT073
Descriptor: Pyruvate dehydrogenase complex repressor
Authors:Brunzelle, J.S, Wawrzak, Z, Sandoval, J, Skarina, T, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2016-07-15
Release date:2016-11-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:X-Ray Crystal Structure of a Fragment (1-75) of a Transcriptional Regulator PdhR from Escherichia coli CFT073
To Be Published

 

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