1XFH
 
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2NWL
 | | Crystal structure of GltPh in complex with L-Asp | | Descriptor: | ASPARTIC ACID, PALMITIC ACID, glutamate symport protein | | Authors: | Gouaux, E, Boudker, O, Ryan, R, Yernool, D, Shimamoto, K. | | Deposit date: | 2006-11-15 | | Release date: | 2007-02-27 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.96 Å) | | Cite: | Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter.
Nature, 445, 2007
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2NWW
 | | Crystal structure of GltPh in complex with TBOA | | Descriptor: | (3S)-3-(BENZYLOXY)-L-ASPARTIC ACID, 425aa long hypothetical proton glutamate symport protein | | Authors: | Gouaux, E, Boudker, O, Ryan, R, Yernool, D, Shimamoto, K. | | Deposit date: | 2006-11-16 | | Release date: | 2007-02-27 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter.
Nature, 445, 2007
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2NWX
 | | Crystal structure of GltPh in complex with L-aspartate and sodium ions | | Descriptor: | 425aa long hypothetical proton glutamate symport protein, ASPARTIC ACID, PALMITIC ACID, ... | | Authors: | Gouaux, E, Boudker, O, Ryan, R, Yernool, D, Shimamoto, K. | | Deposit date: | 2006-11-16 | | Release date: | 2007-02-27 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.29 Å) | | Cite: | Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter.
Nature, 445, 2007
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3KBC
 | | Crystal structure of GltPh K55C-A364C mutant crosslinked with divalent mercury | | Descriptor: | 425aa long hypothetical proton glutamate symport protein, ASPARTIC ACID, MERCURY (II) ION, ... | | Authors: | Reyes, N, Ginter, C, Boudker, O. | | Deposit date: | 2009-10-20 | | Release date: | 2009-12-01 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.51 Å) | | Cite: | Transport mechanism of a bacterial homologue of glutamate transporters.
Nature, 462, 2009
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3V8F
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3V8G
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4IZM
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4KY0
 | | Crystal structure of a substrate-free glutamate transporter homologue from Thermococcus kodakarensis | | Descriptor: | Proton/glutamate symporter, SDF family, TETRAETHYLENE GLYCOL | | Authors: | Guskov, A, Jensen, S, Rempel, S, Hanelt, I, Slotboom, D.J. | | Deposit date: | 2013-05-28 | | Release date: | 2013-09-11 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structure of a substrate-free aspartate transporter.
Nat.Struct.Mol.Biol., 20, 2013
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4OYE
 | | Crystal structure of GltPh R397A in apo | | Descriptor: | 425aa long hypothetical proton glutamate symport protein | | Authors: | Boudker, O, Oh, S. | | Deposit date: | 2014-02-11 | | Release date: | 2014-09-17 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (4 Å) | | Cite: | Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
Elife, 3, 2014
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4OYF
 | | Crystal structure of GLTPH R397A IN Sodium-bound state | | Descriptor: | GLUTAMATE SYMPORT PROTEIN, SODIUM ION | | Authors: | Boudker, O, Oh, S, Verdon, G, Serio, R. | | Deposit date: | 2014-02-11 | | Release date: | 2014-08-13 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.41 Å) | | Cite: | Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
Elife, 3, 2014
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4P19
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4P1A
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4P3J
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4P6H
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4X2S
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5CFY
 | | CRYSTAL STRUCTURE OF GLTPH R397A IN COMPLEX WITH NA+ AND L-ASP | | Descriptor: | 425aa long hypothetical proton glutamate symport protein, ASPARTIC ACID, SODIUM ION | | Authors: | Boudker, O, Oh, S. | | Deposit date: | 2015-07-08 | | Release date: | 2016-04-20 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
Elife, 3, 2014
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5DWY
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5E9S
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5LLM
 | | Structure of the thermostabilized EAAT1 cryst mutant in complex with L-ASP and the allosteric inhibitor UCPH101 | | Descriptor: | 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, ASPARTIC ACID, Excitatory amino acid transporter 1,Neutral amino acid transporter B(0),Excitatory amino acid transporter 1, ... | | Authors: | Canul-Tec, J, Assal, R, Legrand, P, Reyes, N. | | Deposit date: | 2016-07-27 | | Release date: | 2017-04-19 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | Structure and allosteric inhibition of excitatory amino acid transporter 1.
Nature, 544, 2017
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5LLU
 | | Structure of the thermostabilized EAAT1 cryst-II mutant in complex with L-ASP | | Descriptor: | ASPARTIC ACID, Excitatory amino acid transporter 1,Neutral amino acid transporter B(0),Excitatory amino acid transporter 1, SODIUM ION | | Authors: | Canul-Tec, J, Assal, R, Legrand, P, Reyes, N. | | Deposit date: | 2016-07-28 | | Release date: | 2017-04-19 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.32 Å) | | Cite: | Structure and allosteric inhibition of excitatory amino acid transporter 1.
Nature, 544, 2017
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5LM4
 | | Structure of the thermostalilized EAAT1 cryst-II mutant in complex with L-ASP and the allosteric inhibitor UCPH101 | | Descriptor: | 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, ASPARTIC ACID, Excitatory amino acid transporter 1,Neutral amino acid transporter B(0),Excitatory amino acid transporter 1, ... | | Authors: | Canul-Tec, J, Assal, R, Legrand, P, Reyes, N. | | Deposit date: | 2016-07-29 | | Release date: | 2017-04-19 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structure and allosteric inhibition of excitatory amino acid transporter 1.
Nature, 544, 2017
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5MJU
 | | Structure of the thermostabilized EAAT1 cryst mutant in complex with the competititve inhibitor TFB-TBOA and the allosteric inhibitor UCPH101 | | Descriptor: | (2~{S},3~{S})-2-azanyl-3-[[3-[[4-(trifluoromethyl)phenyl]carbonylamino]phenyl]methoxy]butanedioic acid, 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, Excitatory amino acid transporter 1,Neutral amino acid transporter B(0),Excitatory amino acid transporter 1 | | Authors: | Canul-Tec, J, Assal, R, Legrand, P, Reyes, N. | | Deposit date: | 2016-12-01 | | Release date: | 2017-04-19 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.71 Å) | | Cite: | Structure and allosteric inhibition of excitatory amino acid transporter 1.
Nature, 544, 2017
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6BAT
 | | Crystal Structure of Wild-Type GltPh in complex with L-aspartate | | Descriptor: | ASPARTIC ACID, Glutamate transporter homolog, SODIUM ION | | Authors: | Font, J, Scopelliti, A.J, Vandenberg, R.J, Boudker, O, Ryan, R.M. | | Deposit date: | 2017-10-15 | | Release date: | 2018-01-17 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5.
Nat Commun, 9, 2018
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6BAU
 | | Crystal Structure of GltPh R397C in complex with L-Cysteine | | Descriptor: | CYSTEINE, Glutamate transporter homolog, SODIUM ION | | Authors: | Font, J, Scopelliti, A.J, Vandenberg, R.J, Boudker, O, Ryan, R.M. | | Deposit date: | 2017-10-15 | | Release date: | 2018-01-17 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5.
Nat Commun, 9, 2018
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