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1EF1
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CRYSTAL STRUCTURE OF THE MOESIN FERM DOMAIN/TAIL DOMAIN COMPLEX
Descriptor: MOESIN, SULFATE ION
Authors:Pearson, M.A, Reczek, D, Bretscher, A, Karplus, P.A.
Deposit date:2000-02-04
Release date:2000-05-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain.
Cell(Cambridge,Mass.), 101, 2000
1GC7
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CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN
Descriptor: RADIXIN
Authors:Hamada, K, Shimizu, T, Matsui, T, Tsukita, S, Tsukita, S, Hakoshima, T.
Deposit date:2000-07-21
Release date:2000-09-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain.
EMBO J., 19, 2000
1GC6
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CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN COMPLEXED WITH INOSITOL-(1,4,5)-TRIPHOSPHATE
Descriptor: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, RADIXIN
Authors:Hamada, K, Shimizu, T, Matsui, T, Tsukita, S, Tsukita, S, Hakoshima, T.
Deposit date:2000-07-21
Release date:2000-09-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain.
EMBO J., 19, 2000
1GG3
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CRYSTAL STRUCTURE OF THE PROTEIN 4.1R MEMBRANE BINDING DOMAIN
Descriptor: ERYTHROID MEMBRANE PROTEIN 4.1R
Authors:Han, B.G.
Deposit date:2000-07-11
Release date:2001-01-10
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Protein 4.1R core domain structure and insights into regulation of cytoskeletal organization.
Nat.Struct.Biol., 7, 2000
1E5W
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Structure of isolated FERM domain and first long helix of moesin
Descriptor: MOESIN
Authors:Edwards, S.D, Keep, N.H.
Deposit date:2000-08-03
Release date:2001-06-27
Last modified:2015-02-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The 2.7 A Crystal Structure of the Activated Ferm Domain of Moesin: An Analysis of Structural Changes on Activation
Biochemistry, 40, 2001
1H4R
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Crystal Structure of the FERM domain of Merlin, the Neurofibromatosis 2 Tumor Suppressor Protein.
Descriptor: MERLIN, SULFATE ION
Authors:Cooper, D.R, Kang, B.S, Sheffield, P, Devedjiev, Y, Derewenda, Z.S.
Deposit date:2001-05-14
Release date:2002-01-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Structure of the Ferm Domain of Merlin, the Neurofibromatosis Type 2 Gene Product.
Acta Crystallogr.,Sect.D, 58, 2002
1ISN
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Crystal structure of merlin FERM domain
Descriptor: merlin
Authors:Shimizu, T, Seto, A, Maita, N, Hamada, K, Tsukita, S, Tsukita, S, Hakoshima, T.
Deposit date:2001-12-13
Release date:2002-04-03
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for neurofibromatosis type 2. Crystal structure of the merlin FERM domain.
J.Biol.Chem., 277, 2002
1MIX
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BU of 1mix by Molmil
Crystal structure of a FERM domain of Talin
Descriptor: Talin
Authors:Garcia-Alvarez, B, de Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
Deposit date:2002-08-23
Release date:2003-01-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural determinants of integrin recognition by talin
Mol.Cell, 11, 2003
1MK7
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CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA
Descriptor: Integrin Beta3, TALIN
Authors:Garcia-Alvarez, B, De Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
Deposit date:2002-08-28
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Determinants of Integrin Recognition by Talin
Mol.Cell, 11, 2003
1MIZ
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Crystal structure of an integrin beta3-talin chimera
Descriptor: TALIN, integrin beta3
Authors:Garcia-Alvarez, B, de Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
Deposit date:2002-08-23
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural determinants of integrin recognition by talin
Mol.Cell, 11, 2003
1MK9
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CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA
Descriptor: Integrin Beta3, TALIN
Authors:Garcia-Alvarez, B, De Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
Deposit date:2002-08-28
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Determinants of Integrin Recognition by Talin
Mol.Cell, 11, 2003
1NI2
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Structure of the active FERM domain of Ezrin
Descriptor: Ezrin
Authors:Smith, W.J, Nassar, N, Bretscher, A.P, Cerione, R.A, Karplus, P.A.
Deposit date:2002-12-20
Release date:2003-02-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the Active N-terminal Domain of Ezrin. CONFORMATIONAL AND MOBILITY CHANGES IDENTIFY KEYSTONE INTERACTIONS.
J.Biol.Chem., 278, 2003
1J19
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Crystal structure of the radxin FERM domain complexed with the ICAM-2 cytoplasmic peptide
Descriptor: 16-mer peptide from Intercellular adhesion molecule-2, radixin
Authors:Hamada, K, Shimizu, T, Yonemura, S, Tsukita, S, Tsukita, S, Hakoshima, T.
Deposit date:2002-12-02
Release date:2003-03-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex
EMBO J., 22, 2003
1SGH
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BU of 1sgh by Molmil
Moesin FERM domain bound to EBP50 C-terminal peptide
Descriptor: Ezrin-radixin-moesin binding phosphoprotein 50, Moesin
Authors:Finnerty, C.M, Chambers, D, Ingraffea, J, Faber, H.R, Karplus, P.A, Bretscher, A.
Deposit date:2004-02-23
Release date:2004-06-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The EBP50-moesin interaction involves a binding site regulated by direct masking on the FERM domain
J.Cell.Sci., 117, 2004
1Y19
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BU of 1y19 by Molmil
Structural basis for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions
Descriptor: Phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma, Talin 1
Authors:de Pereda, J.M, Wegener, K, Santelli, E, Bate, N, Ginsberg, M.H, Critchley, D.R, Campbell, I.D, Liddington, R.C.
Deposit date:2004-11-17
Release date:2005-01-04
Last modified:2016-11-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural bases for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions
J.Biol.Chem., 280, 2005
2AEH
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Focal adhesion kinase 1
Descriptor: Focal adhesion kinase 1
Authors:Ceccarelli, D.F, Song, H.K, Poy, F, Schaller, M.D, Eck, M.J.
Deposit date:2005-07-22
Release date:2005-10-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Crystal Structure of the FERM Domain of Focal Adhesion Kinase
J.Biol.Chem., 281, 2006
2AL6
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FERM domain of Focal Adhesion Kinase
Descriptor: Focal adhesion kinase 1
Authors:Ceccarelli, D.F, Song, H.K, Poy, F, Schaller, M.D, Eck, M.J.
Deposit date:2005-08-04
Release date:2005-10-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal Structure of the FERM Domain of Focal Adhesion Kinase
J.Biol.Chem., 281, 2006
2D2Q
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BU of 2d2q by Molmil
Crystal structure of the dimerized radixin FERM domain
Descriptor: Radixin
Authors:Kitano, K, Yusa, F, Hakoshima, T.
Deposit date:2005-09-15
Release date:2006-04-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of dimerized radixin FERM domain suggests a novel masking motif in C-terminal residues 295-304
ACTA CRYSTALLOGR.,SECT.F, 62, 2006
2HE7
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FERM domain of EPB41L3 (DAL-1)
Descriptor: Band 4.1-like protein 3
Authors:Hallberg, B.M, Busam, R.D, Arrowsmith, C, Berglund, H, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Schiavone, L.H, Johansson, I, Hogbom, M, Karlberg, T, Kotenyova, T, Nilvebrandt, J, Norberg, P, Stenmark, P, Nordlund, P, Nilsson-ehle, P, Nyman, T, Ogg, D, Sagemark, J, Sundstrom, M, Uppenberg, J, Van den berg, S, Weigelt, J, Persson, C, Thorsell, A.G, Structural Genomics Consortium (SGC)
Deposit date:2006-06-21
Release date:2006-07-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of tumor suppressor in lung cancer 1 (TSLC1) binding to differentially expressed in adenocarcinoma of the lung (DAL-1/4.1B).
J.Biol.Chem., 286, 2011
2D10
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Crystal structure of the Radixin FERM domain complexed with the NHERF-1 C-terminal tail peptide
Descriptor: Ezrin-radixin-moesin binding phosphoprotein 50, Radixin
Authors:Terawaki, S, Maesaki, R, Hakoshima, T.
Deposit date:2005-08-11
Release date:2006-07-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for NHERF recognition by ERM proteins
Structure, 14, 2006
2D11
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Crystal structure of the Radixin FERM domain complexed with the NHERF-2 C-terminal tail peptide
Descriptor: Na(+)/H(+) exchange regulatory cofactor NHE-RF2, Radixin
Authors:Terawaki, S, Maesaki, R, Hakoshima, T.
Deposit date:2005-08-11
Release date:2006-07-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structural basis for NHERF recognition by ERM proteins
Structure, 14, 2006
2I1J
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Moesin from Spodoptera frugiperda at 2.1 angstroms resolution
Descriptor: CHLORIDE ION, GLYCEROL, Moesin, ...
Authors:Li, Q, Nance, M.R, Tesmer, J.J.G.
Deposit date:2006-08-14
Release date:2006-12-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Self-masking in an Intact ERM-merlin Protein: An Active Role for the Central alpha-Helical Domain.
J.Mol.Biol., 365, 2007
2I1K
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Moesin from Spodoptera frugiperda reveals the coiled-coil domain at 3.0 angstrom resolution
Descriptor: CHLORIDE ION, GLYCEROL, Moesin, ...
Authors:Nance, M.R, Tesmer, J.J.G.
Deposit date:2006-08-14
Release date:2006-12-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Self-masking in an Intact ERM-merlin Protein: An Active Role for the Central alpha-Helical Domain.
J.Mol.Biol., 365, 2007
2YVC
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Crystal structure of the Radixin FERM domain complexed with the NEP cytoplasmic tail
Descriptor: Neprilysin, Radixin
Authors:Terawaki, S, Kitano, K, Hakoshima, T.
Deposit date:2007-04-11
Release date:2007-04-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for type II membrane protein binding by ERM proteins revealed by the radixin-neutral endopeptidase 24.11 (NEP) complex
J.Biol.Chem., 282, 2007
2J0J
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Crystal structure of a fragment of focal adhesion kinase containing the FERM and kinase domains.
Descriptor: 1,2,3,4-TETRAHYDROGEN-STAUROSPORINE, FOCAL ADHESION KINASE 1
Authors:Lietha, D, Cai, X, Li, Y, Schaller, M.D, Eck, M.J.
Deposit date:2006-08-03
Release date:2007-06-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for the Autoinhibition of Focal Adhesion Kinase
Cell(Cambridge,Mass.), 129, 2007

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