1HIB
 
 | | THE STRUCTURE OF AN INTERLEUKIN-1 BETA MUTANT WITH REDUCED BIOACTIVITY SHOWS MULTIPLE SUBTLE CHANGES IN CONFORMATION THAT AFFECT PROTEIN-PROTEIN RECOGNITION | | Descriptor: | INTERLEUKIN-1 BETA | | Authors: | Camacho, N.P, Smith, D.R, Goldman, A, Schneider, B, Green, D, Young, P.R, Berman, H.M. | | Deposit date: | 1993-03-29 | | Release date: | 1994-01-31 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of an interleukin-1 beta mutant with reduced bioactivity shows multiple subtle changes in conformation that affect protein-protein recognition.
Biochemistry, 32, 1993
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1I1B
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1ILR
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1ILT
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1IOB
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1IRA
 | | COMPLEX OF THE INTERLEUKIN-1 RECEPTOR WITH THE INTERLEUKIN-1 RECEPTOR ANTAGONIST (IL1RA) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, INTERLEUKIN-1 RECEPTOR, INTERLEUKIN-1 RECEPTOR ANTAGONIST | | Authors: | Schreuder, H.A, Tardif, C, Tramp-Kalmeyer, S, Soffientini, A, Sarubbi, E, Akeson, A, Bowlin, T, Yanofsky, S, Barrett, R.W. | | Deposit date: | 1998-04-09 | | Release date: | 1998-06-17 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | A new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist.
Nature, 386, 1997
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1IRP
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1ITB
 | | TYPE-1 INTERLEUKIN-1 RECEPTOR COMPLEXED WITH INTERLEUKIN-1 BETA | | Descriptor: | INTERLEUKIN-1 BETA, TYPE 1 INTERLEUKIN-1 RECEPTOR | | Authors: | Vigers, G.P.A, Anderson, L.J, Caffes, P, Brandhuber, B.J. | | Deposit date: | 1997-01-15 | | Release date: | 1998-02-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of the type-I interleukin-1 receptor complexed with interleukin-1beta.
Nature, 386, 1997
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1J0S
 | | Solution structure of the human interleukin-18 | | Descriptor: | Interleukin-18 | | Authors: | Kato, Z, Jee, J, Shikano, H, Mishima, M, Ohki, I, Yoneda, T, Hara, T, Torigoe, K, Kondo, N, Shirakawa, M. | | Deposit date: | 2002-11-21 | | Release date: | 2003-11-11 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | The structure and binding mode of interleukin-18
Nat.Struct.Biol., 10, 2003
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1L2H
 | | Crystal structure of Interleukin 1-beta F42W/W120F mutant | | Descriptor: | Interleukin 1-beta | | Authors: | Rudolph, M.G, Kelker, M.S, Schneider, T.R, Yeates, T.O, Oseroff, V, Heidary, D.K, Jennings, P.A, Wilson, I.A. | | Deposit date: | 2002-02-21 | | Release date: | 2003-02-04 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | Use of multiple anomalous dispersion to phase highly merohedrally twinned crystals of interleukin-1beta.
Acta Crystallogr.,Sect.D, 59, 2003
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1MD6
 | | High resolution crystal structure of murine IL-1F5 reveals unique loop conformation for specificity | | Descriptor: | interleukin 1 family, member 5 (delta) | | Authors: | Pei, X.Y, Dunn, E.F, Gay, N.J, O'Neill, L.A. | | Deposit date: | 2002-08-07 | | Release date: | 2003-09-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | High-Resolution Structure of Murine Interleukin 1 Homologue IL-1F5 Reveals Unique Loop Conformations for Receptor Binding Specificity.
Biochemistry, 42, 2003
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1S0L
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1T4Q
 | | Interleukin 1 beta F101W | | Descriptor: | Interleukin-1 beta | | Authors: | Adamek, D.H, Guerrero, L, Caspar, D.L. | | Deposit date: | 2004-04-30 | | Release date: | 2004-12-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural and energetic consequences of mutations in a solvated hydrophobic cavity.
J.Mol.Biol., 346, 2005
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1TOO
 | | Interleukin 1B Mutant F146W | | Descriptor: | Interleukin-1 beta | | Authors: | Adamek, D.H, Guerrero, L, Caspar, D.L. | | Deposit date: | 2004-06-14 | | Release date: | 2004-12-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural and energetic consequences of mutations in a solvated hydrophobic cavity.
J.Mol.Biol., 346, 2005
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1TP0
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1TWE
 | | INTERLEUKIN 1 BETA MUTANT F101Y | | Descriptor: | Interleukin-1 beta | | Authors: | Adamek, D.H, Capsar, D.L. | | Deposit date: | 2004-06-30 | | Release date: | 2004-12-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural and energetic consequences of mutations in a solvated hydrophobic cavity.
J.Mol.Biol., 346, 2005
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1TWM
 | | Interleukin-1 Beta Mutant F146Y | | Descriptor: | Interleukin-1 beta | | Authors: | Adamek, D.H, Capsar, D.L. | | Deposit date: | 2004-07-01 | | Release date: | 2004-12-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.26 Å) | | Cite: | Structural and energetic consequences of mutations in a solvated hydrophobic cavity.
J.Mol.Biol., 346, 2005
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21BI
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2I1B
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2ILA
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2IRT
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2KH2
 | | Solution structure of a scFv-IL-1B complex | | Descriptor: | Interleukin-1 beta, scFv | | Authors: | Wilkinson, I.C, Hall, C.J, Veverka, V, Muskett, F.W, Stephens, P.E, Taylor, R.J, Henry, A.J, Carr, M.D. | | Deposit date: | 2009-03-23 | | Release date: | 2009-09-08 | | Last modified: | 2022-03-16 | | Method: | SOLUTION NMR | | Cite: | High resolution NMR-based model for the structure of a scFv-IL-1beta complex: potential for NMR as a key tool in therapeutic antibody design and development.
J.Biol.Chem., 284, 2009
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2KKI
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2L5X
 | | Solution structure of IL1A-S100A13 complex | | Descriptor: | Interleukin-1 alpha, Protein S100-A13 | | Authors: | Mohan, S.K, Yu, C. | | Deposit date: | 2010-11-09 | | Release date: | 2011-01-26 | | Last modified: | 2016-01-13 | | Method: | SOLUTION NMR | | Cite: | The IL1alpha-S100A13 heterotetrameric complex structure: a component in the non-classical pathway for interleukin 1alpha secretion
J.Biol.Chem., 286, 2011
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2MIB
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