PDB: 166 resultsInfo pagesStatus searchChemie searchBIRD

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6GP3	Ribonucleotide Reductase class Ie R2 from Mesoplasma florum, inactive form Descriptor: CALCIUM ION, Ribonucleoside-diphosphate reductase beta chain Authors: Srinivas, V, Lebrette, H, Lundin, D, Kutin, Y, Sahlin, M, Lerche, M, Enrich, J, Branca, R.M.M, Cox, N, Sjoberg, B.M, Hogbom, M. Deposit date: 2018-06-05 Release date: 2018-08-22 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.23 Å) Cite: Metal-free ribonucleotide reduction powered by a DOPA radical in Mycoplasma pathogens. Nature, 563, 2018
6QO9	Crystal structure of ribonucleotide reductase NrdF from Bacillus anthracis soaked with manganese ions Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MANGANESE (II) ION, Ribonucleoside-diphosphate reductase subunit beta, ... Authors: Grave, K, Hogbom, M. Deposit date: 2019-02-12 Release date: 2019-08-21 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.299 Å) Cite: Redox-induced structural changes in the di-iron and di-manganese forms of Bacillus anthracis ribonucleotide reductase subunit NrdF suggest a mechanism for gating of radical access. J.Biol.Inorg.Chem., 24, 2019
6QO8	Crystal structure of ribonucleotide reductase NrdF from Bacillus anthracis anaerobically soaked with ferrous ions Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FE (II) ION, Ribonucleoside-diphosphate reductase subunit beta, ... Authors: Grave, K, Hogbom, M. Deposit date: 2019-02-12 Release date: 2019-08-21 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.31921768 Å) Cite: Redox-induced structural changes in the di-iron and di-manganese forms of Bacillus anthracis ribonucleotide reductase subunit NrdF suggest a mechanism for gating of radical access. J.Biol.Inorg.Chem., 24, 2019
8BT4	Ribonucleotide Reductase class Ie R2 from Mesoplasma florum, radical-lost ground state Descriptor: CALCIUM ION, GLYCEROL, Ribonucleoside-diphosphate reductase Authors: Lebrette, H, Srinivas, V, Hogbom, M. Deposit date: 2022-11-27 Release date: 2023-11-01 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Structure of a ribonucleotide reductase R2 protein radical. Science, 382, 2023
6TQV	Crystal structure of ribonucleotide reductase NrdF from Bacillus anthracis aerobically soaked with Fe(II) and Mn(II) ions Descriptor: MANGANESE (II) ION, Ribonucleoside-diphosphate reductase subunit beta, SULFATE ION Authors: Grave, K, Hogbom, M. Deposit date: 2019-12-17 Release date: 2020-04-15 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.35000968 Å) Cite: The Bacillus anthracis class Ib ribonucleotide reductase subunit NrdF intrinsically selects manganese over iron. J.Biol.Inorg.Chem., 25, 2020
3MJO	Small subunit (R2F) of native ribonucleotide reductase from Corynebacterium ammoniagenes Descriptor: MANGANESE (III) ION, Ribonucleotide reductase subunit R2F Authors: Ogata, H, Stolle, P, Stehr, M, Auling, G, Lubitz, W. Deposit date: 2010-04-13 Release date: 2010-08-25 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.36 Å) Cite: A Tyrosyl-Dimanganese Coupled Spin System is the Native Metalloradical Cofactor of the R2F Subunit of the Ribonucleotide Reductase of Corynebacterium ammoniagenes. J.Am.Chem.Soc., 132, 2010
7QBP	Crystal structure of R2-like ligand-binding oxidase from Saccharopolyspora Erythraea Descriptor: FE (III) ION, MANGANESE (III) ION, PALMITIC ACID, ... Authors: Srinivas, V, Diamanti, R, Lebrette, H, Hogbom, M. Deposit date: 2021-11-19 Release date: 2022-04-06 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.38 Å) Cite: Comparative structural analysis provides new insights into the function of R2-like ligand-binding oxidase. Febs Lett., 596, 2022
6F6M	R2-like ligand-binding oxidase Y162F mutant with anaerobically reconstituted Mn/Fe cofactor Descriptor: FE (II) ION, MANGANESE (II) ION, PALMITIC ACID, ... Authors: Griese, J.J, Hogbom, M. Deposit date: 2017-12-05 Release date: 2018-12-19 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.393 Å) Cite: Assembly of a heterodinuclear Mn/Fe cofactor is coupled to tyrosine-valine ether cross-link formation in the R2-like ligand-binding oxidase. J. Biol. Inorg. Chem., 24, 2019
1MXR	High resolution structure of Ribonucleotide reductase R2 from E. coli in its oxidised (Met) form Descriptor: FE (III) ION, GLYCEROL, MERCURY (II) ION, ... Authors: Andersson, M.A, Hogbom, M, Nordlund, P. Deposit date: 2002-10-03 Release date: 2003-03-25 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Displacement of the tyrosyl radical cofactor in ribonucleotide reductase obtained by single-crystal high-field EPR and 1.4-A x-ray data. Proc.Natl.Acad.Sci.Usa, 100, 2003
6QOB	Crystal structure of ribonucleotide reductase NrdF from Bacillus anthracis with partially oxidised di-iron metallocofactor Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FE (III) ION, Ribonucleoside-diphosphate reductase subunit beta, ... Authors: Grave, K, Hogbom, M. Deposit date: 2019-02-12 Release date: 2019-08-21 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.457 Å) Cite: Redox-induced structural changes in the di-iron and di-manganese forms of Bacillus anthracis ribonucleotide reductase subunit NrdF suggest a mechanism for gating of radical access. J.Biol.Inorg.Chem., 24, 2019
6GP2	Ribonucleotide Reductase class Ie R2 from Mesoplasma florum, DOPA-active form Descriptor: CALCIUM ION, Ribonucleoside-diphosphate reductase beta chain Authors: Srinivas, V, Lebrette, H, Lundin, D, Kutin, Y, Sahlin, M, Lerche, M, Enrich, J, Branca, R.M.M, Cox, N, Sjoberg, B.M, Hogbom, M. Deposit date: 2018-06-05 Release date: 2018-08-22 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.48 Å) Cite: Metal-free ribonucleotide reduction powered by a DOPA radical in Mycoplasma pathogens. Nature, 563, 2018
8BT3	Ribonucleotide Reductase class Ie R2 from Mesoplasma florum, catalytically active radical state solved by XFEL Descriptor: Ribonucleoside-diphosphate reductase beta chain Authors: Lebrette, H, Srinivas, V, Hogbom, M. Deposit date: 2022-11-27 Release date: 2023-11-01 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structure of a ribonucleotide reductase R2 protein radical. Science, 382, 2023
6QO5	Crystal structure of apo (metal-free) ribonucleotide reductase NrdF from Bacillus anthracis Descriptor: CHLORIDE ION, Ribonucleoside-diphosphate reductase subunit beta, SULFATE ION Authors: Grave, K, Hogbom, M. Deposit date: 2019-02-12 Release date: 2019-08-21 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.511 Å) Cite: Redox-induced structural changes in the di-iron and di-manganese forms of Bacillus anthracis ribonucleotide reductase subunit NrdF suggest a mechanism for gating of radical access. J.Biol.Inorg.Chem., 24, 2019
7MMT	Crystal Structure of the Class Ie Ribonucleotide Reductase Beta Subunit from Aerococcus urinae with Cu(I) bound (Cu chloride soak) Descriptor: CHLORIDE ION, COPPER (I) ION, GLYCEROL, ... Authors: Palowitch, G.M, Boal, A.K. Deposit date: 2021-04-30 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.54 Å) Cite: Ribonucleotide Reductase To be published
7MMW	Crystal Structure of the Class Ie Ribonucleotide Reductase Beta Subunit from Aerococcus urinae (in alternate conformation) Descriptor: CALCIUM ION, Ribonucleoside-diphosphate reductase Authors: Palowitch, G.M, Boal, A.K. Deposit date: 2021-04-30 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Ribonucleotide Reductase To be published
6TQW	Crystal structure of ribonucleotide reductase NrdF from Bacillus anthracis anaerobically soaked with Fe(II) and Mn(II) ions Descriptor: MANGANESE (II) ION, Ribonucleoside-diphosphate reductase subunit beta, SULFATE ION Authors: Grave, K, Hogbom, M. Deposit date: 2019-12-17 Release date: 2020-04-15 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.55 Å) Cite: The Bacillus anthracis class Ib ribonucleotide reductase subunit NrdF intrinsically selects manganese over iron. J.Biol.Inorg.Chem., 25, 2020
6EBO	Crystal Structure of the Class Ie Ribonucleotide Reductase Beta Subunit from Aerococcus urinae in Unactivated Form Descriptor: CALCIUM ION, GLYCEROL, Ribonucleoside-diphosphate reductase, ... Authors: Palowitch, G.M, Alapati, R.B, Boal, A.K. Deposit date: 2018-08-06 Release date: 2018-09-19 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.58 Å) Cite: Metal-free class Ie ribonucleotide reductase from pathogens initiates catalysis with a tyrosine-derived dihydroxyphenylalanine radical. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6EBP	Crystal Structure of the Class Ie Ribonucleotide Reductase Beta Subunit from Aerococcus urinae in Activated Form Descriptor: CALCIUM ION, GLYCEROL, Ribonucleoside-diphosphate reductase, ... Authors: Palowitch, G.M, Boal, A.K. Deposit date: 2018-08-06 Release date: 2018-09-19 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.59 Å) Cite: Metal-free class Ie ribonucleotide reductase from pathogens initiates catalysis with a tyrosine-derived dihydroxyphenylalanine radical. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6QK2	R2-like ligand-binding oxidase Y715F mutant with anaerobically reconstituted Mn/Fe cofactor Descriptor: FE (II) ION, MANGANESE (II) ION, PALMITIC ACID, ... Authors: Griese, J.J, Hogbom, M. Deposit date: 2019-01-28 Release date: 2020-02-19 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.596 Å) Cite: Key Structural Motifs Balance Metal Binding and Oxidative Reactivity in a Heterobimetallic Mn/Fe Protein. J.Am.Chem.Soc., 142, 2020
1JQC	Mn substituted Ribonucleotide reductase R2 from E. Coli oxidized by hydrogen peroxide and hydroxylamine Descriptor: MANGANESE (II) ION, MERCURY (II) ION, Protein R2 of ribonucleotide reductase Authors: Hogbom, M, Andersson, M.E, Nordlund, P. Deposit date: 2001-08-06 Release date: 2001-08-22 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.61 Å) Cite: Crystal structures of oxidized dinuclear manganese centres in Mn-substituted class I ribonucleotide reductase from Escherichia coli: carboxylate shifts with implications for O2 activation and radical generation. J.Biol.Inorg.Chem., 6, 2001
6F6E	R2-like ligand-binding oxidase V72A mutant with anaerobically reconstituted Mn/Fe cofactor Descriptor: FE (II) ION, MANGANESE (II) ION, PALMITIC ACID, ... Authors: Griese, J.J, Hogbom, M. Deposit date: 2017-12-05 Release date: 2018-07-04 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.627 Å) Cite: Ether cross-link formation in the R2-like ligand-binding oxidase. J. Biol. Inorg. Chem., 23, 2018
6QO7	Crystal structure of ribonucleotide reductase NrdF from Bacillus anthracis aerobically soaked with ferrous ions (photo-reduced) Descriptor: CHLORIDE ION, FE (II) ION, Ribonucleoside-diphosphate reductase subunit beta Authors: Grave, K, Hogbom, M. Deposit date: 2019-02-12 Release date: 2019-08-21 Last modified: 2019-10-02 Method: X-RAY DIFFRACTION (1.628 Å) Cite: Redox-induced structural changes in the di-iron and di-manganese forms of Bacillus anthracis ribonucleotide reductase subunit NrdF suggest a mechanism for gating of radical access. J.Biol.Inorg.Chem., 24, 2019
3DHZ	Apo (iron free) structure of C. ammoniagenes R2 protein Descriptor: FE (II) ION, Ribonucleotide reductase subunit R2F Authors: Hogbom, M, Nordlund, P. Deposit date: 2008-06-19 Release date: 2008-07-01 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Structural and mutational studies of the carboxylate cluster in Iron-free Ribonucleotide Reductase R2. Biochemistry, 43, 2004
6I95	R2-like ligand-binding oxidase G68L mutant with anaerobically reconstituted Mn/Fe cofactor Descriptor: FE (II) ION, MANGANESE (II) ION, OCTANOIC ACID (CAPRYLIC ACID), ... Authors: Griese, J.J, Hogbom, M. Deposit date: 2018-11-22 Release date: 2019-10-16 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.646 Å) Cite: Chemical flexibility of heterobimetallic Mn/Fe cofactors: R2lox and R2c proteins. J.Biol.Chem., 294, 2019
3N37	Ribonucleotide Reductase Dimanganese(II)-NrdF from Escherichia coli Descriptor: GLYCEROL, MANGANESE (II) ION, Ribonucleoside-diphosphate reductase 2 subunit beta Authors: Boal, A.K, Cotruvo Jr, J.A, Stubbe, J, Rosenzweig, A.C. Deposit date: 2010-05-19 Release date: 2010-08-18 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structural basis for activation of class Ib ribonucleotide reductase. Science, 329, 2010

 

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