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8SRO
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BU of 8sro by Molmil
FoxP3 tetramer on TTTG repeats
分子名称: DNA 72-mer, Forkhead box protein P3
著者Leng, F, Hur, S.
登録日2023-05-05
公開日2023-10-18
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献FOXP3 recognizes microsatellites and bridges DNA through multimerization.
Nature, 624, 2023
8SRP
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BU of 8srp by Molmil
FoxP3 forms Ladder-like multimer to bridge TTTG repeats
分子名称: DNA 72-mer, Forkhead box protein P3
著者Leng, F, Hur, S.
登録日2023-05-05
公開日2023-10-18
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献FOXP3 recognizes microsatellites and bridges DNA through multimerization.
Nature, 624, 2023
8BZM
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BU of 8bzm by Molmil
FOXK1-ELF1-heterodimer bound to DNA
分子名称: DNA, ETS-related transcription factor Elf-1, Forkhead box protein K1, ...
著者Morgunova, E, Popov, A, Yin, Y, Taipale, J.
登録日2022-12-15
公開日2023-12-27
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献FOXK1-ELF1_heterodimer bound to DNA
To Be Published
7YZD
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BU of 7yzd by Molmil
Crystal structure of the zebrafish FoxH1 bound to the TGTTTACT site (fkh motif GTAAACA)
分子名称: ACETATE ION, DNA (5'-D(*TP*CP*TP*CP*AP*GP*TP*AP*AP*AP*CP*AP*AP*TP*CP*T)-3'), DNA (5'-D(P*AP*GP*AP*TP*TP*GP*TP*TP*TP*AP*CP*TP*GP*AP*GP*A)-3'), ...
著者Pluta, R, Macias, M.J.
登録日2022-02-19
公開日2022-11-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Molecular basis for DNA recognition by the maternal pioneer transcription factor FoxH1.
Nat Commun, 13, 2022
7YZE
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BU of 7yze by Molmil
Crystal structure of the human FoxA2 bound to the TGTTTACT site (forkhead motif GTAAACA)
分子名称: DNA (5'-D(*AP*GP*AP*TP*TP*GP*TP*TP*TP*AP*CP*TP*GP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*CP*AP*GP*TP*AP*AP*AP*CP*AP*AP*TP*CP*T)-3'), Hepatocyte nuclear factor 3-beta, ...
著者Pluta, R, Macias, M.J.
登録日2022-02-19
公開日2022-11-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Molecular basis for DNA recognition by the maternal pioneer transcription factor FoxH1.
Nat Commun, 13, 2022
7YZF
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BU of 7yzf by Molmil
Crystal structure of the human FoxA2 bound to the TGTTTATT site (forkhead motif ATAAACA)
分子名称: DNA (5'-D(P*AP*GP*AP*TP*TP*GP*TP*TP*TP*AP*TP*TP*GP*AP*GP*A)-3'), DNA (5'-D(P*TP*CP*TP*CP*AP*AP*TP*AP*AP*AP*CP*AP*AP*TP*CP*T)-3'), Hepatocyte nuclear factor 3-beta, ...
著者Pluta, R, Macias, M.J.
登録日2022-02-19
公開日2022-11-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Molecular basis for DNA recognition by the maternal pioneer transcription factor FoxH1.
Nat Commun, 13, 2022
7YZB
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BU of 7yzb by Molmil
Crystal structure of the human FoxH1 bound to the TGTGGATT site
分子名称: DNA (5'-D(*AP*GP*AP*TP*TP*GP*TP*GP*GP*AP*TP*TP*GP*CP*GP*A)-3'), DNA (5'-D(*TP*CP*GP*CP*AP*AP*TP*CP*CP*AP*CP*AP*AP*TP*CP*T)-3'), Forkhead box protein H1, ...
著者Pluta, R, Macias, M.J.
登録日2022-02-19
公開日2022-11-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Molecular basis for DNA recognition by the maternal pioneer transcription factor FoxH1.
Nat Commun, 13, 2022
7YZA
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BU of 7yza by Molmil
Crystal structure of the zebrafish FoxH1 bound to the TGTGTATT site
分子名称: DNA (5'-D(*AP*GP*AP*TP*TP*GP*TP*GP*TP*AP*TP*TP*GP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*CP*AP*AP*TP*AP*CP*AP*CP*AP*AP*TP*CP*T)-3'), Forkhead box protein H1, ...
著者Pluta, R, Macias, M.J.
登録日2022-02-19
公開日2022-11-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.18 Å)
主引用文献Molecular basis for DNA recognition by the maternal pioneer transcription factor FoxH1.
Nat Commun, 13, 2022
7YZG
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BU of 7yzg by Molmil
Crystal structure of the Xenopus FoxH1 bound to the TGTGGATT site
分子名称: DNA (5'-D(*CP*AP*GP*AP*TP*TP*GP*TP*GP*GP*AP*TP*TP*GP*AP*G)-3'), DNA (5'-D(*CP*TP*CP*AP*AP*TP*CP*CP*AP*CP*AP*AP*TP*CP*TP*G)-3'), Forkhead box protein H1
著者Pluta, R, Macias, M.J.
登録日2022-02-19
公開日2022-11-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Molecular basis for DNA recognition by the maternal pioneer transcription factor FoxH1.
Nat Commun, 13, 2022
7YZC
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BU of 7yzc by Molmil
Crystal structure of the zebrafish FoxH1 bound to the TGTTTATT site
分子名称: ACETATE ION, DNA (5'-D(*AP*GP*AP*TP*TP*GP*TP*TP*TP*AP*TP*TP*GP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*CP*AP*AP*TP*AP*AP*AP*CP*AP*AP*TP*CP*T)-3'), ...
著者Pluta, R, Macias, M.J.
登録日2022-02-19
公開日2022-11-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Molecular basis for DNA recognition by the maternal pioneer transcription factor FoxH1.
Nat Commun, 13, 2022
7YZ7
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BU of 7yz7 by Molmil
Crystal structure of the zebrafish FoxH1 bound to the TGTGGATT site
分子名称: DNA (5'-D(*AP*GP*AP*TP*TP*GP*TP*GP*GP*AP*TP*TP*GP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*CP*AP*AP*TP*CP*CP*AP*CP*AP*AP*TP*CP*T)-3'), Forkhead box protein H1, ...
著者Pluta, R, Macias, M.J.
登録日2022-02-18
公開日2022-11-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (0.98 Å)
主引用文献Molecular basis for DNA recognition by the maternal pioneer transcription factor FoxH1.
Nat Commun, 13, 2022
7TDW
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BU of 7tdw by Molmil
Structure of FOXP3-DNA complex
分子名称: DNA (5'-D(*AP*AP*AP*TP*TP*TP*GP*TP*TP*TP*AP*CP*TP*C)-3'), DNA (5'-D(P*GP*AP*GP*TP*AP*AP*AP*CP*AP*AP*AP*TP*TP*T)-3'), Forkhead box P3
著者Leng, F, Hur, S.
登録日2022-01-03
公開日2022-08-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献The transcription factor FoxP3 can fold into two dimerization states with divergent implications for regulatory T cell function and immune homeostasis.
Immunity, 55, 2022
7TDX
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BU of 7tdx by Molmil
Structure of FOXP3-DNA complex
分子名称: DNA (5'-D(*AP*AP*AP*TP*TP*TP*GP*TP*TP*TP*AP*CP*TP*C)-3'), DNA (5'-D(P*GP*AP*GP*TP*AP*AP*AP*CP*AP*AP*AP*TP*TP*T)-3'), Forkhead box P3
著者Leng, F, Hur, S.
登録日2022-01-03
公開日2022-08-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The transcription factor FoxP3 can fold into two dimerization states with divergent implications for regulatory T cell function and immune homeostasis.
Immunity, 55, 2022
7VOV
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BU of 7vov by Molmil
The crystal structure of human forkhead box protein in complex with DNA 2
分子名称: DNA (5'-D(P*AP*AP*AP*TP*AP*TP*TP*TP*AP*TP*TP*AP*TP*CP*GP*A)-3'), DNA (5'-D(P*TP*CP*GP*AP*TP*AP*AP*TP*AP*AP*AP*TP*AP*TP*T)-3'), Forkhead box protein L2
著者Choi, Y, Yoon, H.J, Lee, H.H.
登録日2021-10-15
公開日2022-08-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献FOXL2 and FOXA1 cooperatively assemble on the TP53 promoter in alternative dimer configurations.
Nucleic Acids Res., 50, 2022
7VOX
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BU of 7vox by Molmil
The crystal structure of human forkhead box protein A in complex with DNA 2
分子名称: DNA (5'-D(P*AP*AP*AP*TP*AP*TP*TP*TP*AP*TP*TP*AP*TP*CP*GP*A)-3'), DNA (5'-D(P*TP*CP*GP*AP*TP*AP*AP*TP*AP*AP*AP*TP*AP*TP*TP*T)-3'), Hepatocyte nuclear factor 3-alpha, ...
著者Choi, Y, Yoon, H.J, Lee, H.H.
登録日2021-10-15
公開日2022-08-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献FOXL2 and FOXA1 cooperatively assemble on the TP53 promoter in alternative dimer configurations.
Nucleic Acids Res., 50, 2022
7VOU
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BU of 7vou by Molmil
The crystal structure of human forkhead box protein in complex with DNA 1
分子名称: DNA (5'-D(*AP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3'), DNA (5'-D(*CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*T)-3'), Forkhead box protein L2
著者Choi, Y, Yoon, H.J, Lee, H.H.
登録日2021-10-14
公開日2022-08-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献FOXL2 and FOXA1 cooperatively assemble on the TP53 promoter in alternative dimer configurations.
Nucleic Acids Res., 50, 2022
7FJ2
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BU of 7fj2 by Molmil
Structure of FOXM1 homodimer bound to a palindromic DNA site
分子名称: DNA (5'-D(*AP*CP*CP*GP*TP*AP*AP*AP*CP*AP*TP*GP*TP*TP*TP*AP*CP*GP*GP*T)-3'), Forkhead box protein M1
著者Dai, S.Y, Li, J, Zhang, H.J.
登録日2021-08-02
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.098 Å)
主引用文献Mechanistic Insights into the Preference for Tandem Binding Sites in DNA Recognition by FOXM1.
J.Mol.Biol., 434, 2021
7CBY
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BU of 7cby by Molmil
Structure of FOXG1 DNA binding domain bound to DBE2 DNA site
分子名称: DI(HYDROXYETHYL)ETHER, DNA (5'-D(*CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3'), ...
著者Dai, S.Y, Li, J, Chen, Y.H.
登録日2020-06-15
公開日2020-10-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.646 Å)
主引用文献Structural Basis for DNA Recognition by FOXG1 and the Characterization of Disease-causing FOXG1 Mutations.
J.Mol.Biol., 432, 2020
6XAT
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BU of 6xat by Molmil
Crystal structure of the human FoxP4 DNA binding Domain
分子名称: FOXP4 protein, SODIUM ION
著者VIllalobos, P, Castro-Fernandez, V, Medina, E, Gonzalez-Ordenes, F, Maturana, P, Herrera-Morande, A, Ramirez-Sarmiento, C.A, Babul, J.
登録日2020-06-04
公開日2021-06-09
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Unraveling the folding and dimerization properties of the human FoxP subfamily of transcription factors.
Febs Lett., 597, 2023
6LBM
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BU of 6lbm by Molmil
Crystal Structure of FOXC2-DBD bound to a palindromic DNA sequence
分子名称: Forkhead box protein C2, IRE0, MAGNESIUM ION
著者Li, J, Dai, S.Y.
登録日2019-11-14
公開日2021-02-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.841 Å)
主引用文献Mechanism of forkhead transcription factors binding to a novel palindromic DNA site.
Nucleic Acids Res., 49, 2021
6LBI
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BU of 6lbi by Molmil
Crystal Structure of FOXO1-DBD homodimer bound to a palindromic DNA sequence
分子名称: Forkhead box protein O1, IRE0
著者Li, J, Dai, S.Y, Chen, Y.H.
登録日2019-11-14
公開日2021-02-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.067 Å)
主引用文献Mechanism of forkhead transcription factors binding to a novel palindromic DNA site.
Nucleic Acids Res., 49, 2021
6QVW
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BU of 6qvw by Molmil
Solution structure of the free FOXO1 DNA binding domain
分子名称: Forkhead box protein O1
著者Psenakova, K, Obsil, T, Veverka, V, Obsilova, V, Kohoutova, K.
登録日2019-03-05
公開日2019-09-04
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Forkhead Domains of FOXO Transcription Factors Differ in both Overall Conformation and Dynamics.
Cells, 8, 2019
6O3T
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BU of 6o3t by Molmil
Structural basis of FOXC2 and DNA interactions
分子名称: DNA (5'-D(*AP*AP*AP*TP*TP*GP*TP*TP*TP*AP*TP*AP*AP*AP*CP*AP*GP*CP*CP*CP*G)-3'), DNA (5'-D(*TP*TP*CP*GP*GP*GP*CP*TP*GP*TP*TP*TP*AP*TP*AP*AP*AP*CP*AP*AP*T)-3'), Forkhead box protein C2
著者Nam, H.-J, Li, S.
登録日2019-02-27
公開日2020-01-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献Crystal Structure of FOXC2 in Complex with DNA Target.
Acs Omega, 4, 2019
6NCM
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BU of 6ncm by Molmil
Crystal structure of the human FOXN3 DNA binding domain in complex with a forkhead-like (FHL) DNA sequence
分子名称: DNA (5'-D(*AP*TP*AP*GP*CP*GP*TP*CP*TP*TP*AP*GP*CP*AP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*TP*GP*CP*TP*AP*AP*GP*AP*CP*GP*CP*TP*A)-3'), Forkhead box protein N3, ...
著者Rogers, J.M, Jarrett, S.M, Seegar, T.C, Waters, C.T, Hallworth, A.N, Blacklow, S.C, Bulyk, M.L.
登録日2018-12-11
公開日2019-02-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.704 Å)
主引用文献Bispecific Forkhead Transcription Factor FoxN3 Recognizes Two Distinct Motifs with Different DNA Shapes.
Mol. Cell, 74, 2019
6NCE
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BU of 6nce by Molmil
Crystal structure of the human FOXN3 DNA binding domain in complex with a forkhead DNA sequence
分子名称: DNA (5'-D(*AP*CP*AP*TP*TP*GP*TP*TP*TP*AP*CP*TP*TP*AP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*TP*AP*AP*GP*TP*AP*AP*AP*CP*AP*AP*TP*G)-3'), Forkhead box protein N3, ...
著者Rogers, J.M, Jarrett, S.M, Seegar, T.C, Waters, C.T, Hallworth, A.N, Blacklow, S.C, Bulyk, M.L.
登録日2018-12-11
公開日2019-02-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.598 Å)
主引用文献Bispecific Forkhead Transcription Factor FoxN3 Recognizes Two Distinct Motifs with Different DNA Shapes.
Mol. Cell, 74, 2019

 

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