8C47
 
 | |
8BR0
 | | ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin (residue Q3455 to L3863) in complex with 3'deoxyCTP and two manganese cations bound to Latrunculin-B-ADP-Mn-actin | | Descriptor: | 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | | Authors: | Texeira-Nuns, M, Retailleau, P, Renault, L. | | Deposit date: | 2022-11-22 | | Release date: | 2023-09-20 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.218 Å) | | Cite: | Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin.
Plos Pathog., 19, 2023
|
|
8BJJ
 | | ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin, bound to ATP-Mg-actin, human profilin 1 and a sulfate ion | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | Authors: | Teixeira-Nunes, M, Renault, L, Retailleau, P. | | Deposit date: | 2022-11-04 | | Release date: | 2023-09-20 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.699 Å) | | Cite: | Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin.
Plos Pathog., 19, 2023
|
|
8BJI
 | | chimera of ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo fused to a proline-Rich-Domain (PRD) and profilin, bound to ADP-Mg-actin and a sulfate ion | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | | Authors: | Teixeira-Nunes, M, Renault, L, Retailleau, P. | | Deposit date: | 2022-11-04 | | Release date: | 2023-09-20 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin.
Plos Pathog., 19, 2023
|
|
8BJH
 | | chimera of the inactive ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin, with the double mutation K3528M and K3535I, fused to a proline-Rich-Domain (PRD) and profilin, bound to Latrunculin B-ADP-Mg-actin | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | | Authors: | Teixeira-Nunes, M, Renault, L, Retailleau, P. | | Deposit date: | 2022-11-04 | | Release date: | 2023-09-20 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin.
Plos Pathog., 19, 2023
|
|
7SBG
 | |
7SBD
 | |
7PBH
 | |
7P1H
 | | Structure of the V. vulnificus ExoY-G-actin-profilin complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, cytoplasmic 1, ... | | Authors: | Belyy, A, Merino, F, Raunser, S. | | Deposit date: | 2021-07-01 | | Release date: | 2021-11-17 | | Last modified: | 2021-12-01 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Mechanism of actin-dependent activation of nucleotidyl cyclase toxins from bacterial human pathogens.
Nat Commun, 12, 2021
|
|
7KYW
 | | Crystal structure of timothy grass allergen Phl p 12.0101 reveals an unusual profilin dimer | | Descriptor: | CITRIC ACID, Profilin-1 | | Authors: | O'Malley, A, Kapingidza, A.B, Hyduke, N, Dolamore, C, Chruszcz, M. | | Deposit date: | 2020-12-09 | | Release date: | 2021-03-31 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of timothy grass allergen Phl p 12.0101 reveals an unusual profilin dimer.
Acta Biochim.Pol., 68, 2021
|
|
6NBW
 | | Ternary Complex of Beta/Gamma-Actin with Profilin and AnCoA-NAA80 | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | Authors: | Rebowski, G, Boczkowska, M, Dominguez, R. | | Deposit date: | 2018-12-10 | | Release date: | 2020-01-29 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
|
|
6NBE
 | | Ternary Complex of Ac-Alpha-Actin with Profilin and CoA-NAA80 | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | Authors: | Rebowski, G, Boczkowska, M, Dominguez, R. | | Deposit date: | 2018-12-07 | | Release date: | 2020-04-15 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
|
|
6NAS
 | | Ternary Complex of Ac-Alpha-Actin with Profilin and AcCoA-NAA80 | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETYL COENZYME *A, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Rebowski, G, Boczkowska, M, Dominguez, R. | | Deposit date: | 2018-12-06 | | Release date: | 2020-01-29 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
|
|
6MBX
 | |
6IQK
 | | crystal structure of Arabidopsis thaliana Profilin 3 | | Descriptor: | AtPRF3, Profilin-5 | | Authors: | Qiao, Z, Gao, Y. | | Deposit date: | 2018-11-08 | | Release date: | 2019-11-06 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Structural and computational examination of theArabidopsisprofilin-Poly-P complex reveals mechanistic details in profilin-regulated actin assembly.
J.Biol.Chem., 294, 2019
|
|
6IQJ
 | |
6IQI
 | | crystal structure of Arabidopsis thaliana Profilin 2 | | Descriptor: | Profilin-2 | | Authors: | Qiao, Z, Gao, Y. | | Deposit date: | 2018-11-08 | | Release date: | 2019-11-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural and computational examination of theArabidopsisprofilin-Poly-P complex reveals mechanistic details in profilin-regulated actin assembly.
J.Biol.Chem., 294, 2019
|
|
6IQF
 | | crystal structure of Arabidopsis thaliana Profilin 3 | | Descriptor: | PRF3 | | Authors: | Qiao, Z, Gao, Y. | | Deposit date: | 2018-11-07 | | Release date: | 2019-11-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.457 Å) | | Cite: | Structural and computational examination of theArabidopsisprofilin-Poly-P complex reveals mechanistic details in profilin-regulated actin assembly.
J.Biol.Chem., 294, 2019
|
|
6B6J
 | | Structure of profilin Art v4 | | Descriptor: | Profilin-1 | | Authors: | Pye, S.E, Pote, S.S, Chruszcz, M. | | Deposit date: | 2017-10-02 | | Release date: | 2018-10-03 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Comparative structural and thermal stability studies of Cuc m 2.0101, Art v 4.0101 and other allergenic profilins.
Mol.Immunol., 114, 2019
|
|
5ZZB
 | | LokiProfilin2/Rabbit Actin Complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Robinson, R.C, Akil, C. | | Deposit date: | 2018-05-31 | | Release date: | 2018-10-10 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Genomes of Asgard archaea encode profilins that regulate actin.
Nature, 562, 2018
|
|
5YEE
 | |
5YED
 | | Crystal structure of LokiProfilin1 | | Descriptor: | Uncharacterized protein | | Authors: | Robinson, R.C, Akil, C. | | Deposit date: | 2017-09-16 | | Release date: | 2018-09-19 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Genomes of Asgard archaea encode profilins that regulate actin.
Nature, 562, 2018
|
|
5NZC
 | |
5NZB
 | |
5FEG
 | |
