1A0K
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PROFILIN I FROM ARABIDOPSIS THALIANA
Descriptor:PROFILIN
Authors:Shigeta Junior, R., Huddler, D., Lindberg, U., Schutt, C.E.
Deposit date:1997-12-02
Release date:1998-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of a major allergen from plants.
Structure, 5, 1997
1CJF
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PROFILIN BINDS PROLINE-RICH LIGANDS IN TWO DISTINCT AMIDE BACKBONE ORIENTATIONS
Descriptor:PROTEIN (HUMAN PLATELET PROFILIN), PROTEIN (PROLINE PEPTIDE), 7-HYDROXY-4-METHYL-3-(2-HYDROXY-ETHYL)COUMARIN
Authors:Mahoney, N.M., Fedorov, A.A., Fedorov, E., Rozwarski, D.A., Almo, S.C.
Deposit date:1999-04-13
Release date:1999-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Profilin binds proline-rich ligands in two distinct amide backbone orientations.
Nat.Struct.Biol., 6, 1999
1CQA
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BIRCH POLLEN PROFILIN
Descriptor:PROFILIN
Authors:Fedorov, A.A., Ball, T., Mahoney, N.M., Valenta, R., Almo, S.C.
Deposit date:1996-07-26
Release date:1997-02-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The molecular basis for allergen cross-reactivity: crystal structure and IgE-epitope mapping of birch pollen profilin.
Structure, 5, 1997
1FIK
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HUMAN PLATELET PROFILIN I CRYSTALLIZED IN LOW SALT
Descriptor:PROFILIN, PHOSPHATE ION
Authors:Fedorov, A.A., Pollard, T.D., Almo, S.C.
Deposit date:1996-04-29
Release date:1996-11-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Human Profilin at 2.0 Angstroms Resolution
To be Published
1FIL
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HUMAN PLATELET PROFILIN I CRYSTALLIZED IN HIGH SALT ACTIN-BINDING PROTEIN
Descriptor:PROFILIN, SULFATE ION
Authors:Fedorov, A.A., Pollard, T.D., Almo, S.C.
Deposit date:1996-04-29
Release date:1996-11-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Human Profilin at 2.0 Angstroms Resolution
To be Published
1G5U
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LATEX PROFILIN HEVB8
Descriptor:PROFILIN, SODIUM ION
Authors:Fedorov, A.A., Fedorov, E.V., Ganglberger, E., Breiteneder, H., Almo, S.C.
Deposit date:2000-11-02
Release date:2000-11-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A Comparative Structural Analysis of Allergen Profilins HEVB8 and BETV2
To be Published
1PFL
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REFINED SOLUTION STRUCTURE OF HUMAN PROFILIN I
Descriptor:PROFILIN I
Authors:Metzler, W.J., Farmer II, B.T., Constantine, K.L., Friedrichs, M.S., Lavoie, T., Mueller, L.
Deposit date:1994-12-12
Release date:1995-03-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Refined solution structure of human profilin I.
Protein Sci., 4, 1995
1PNE
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CRYSTALLIZATION AND STRUCTURE DETERMINATION OF BOVINE PROFILIN AT 2.0 ANGSTROMS RESOLUTION
Descriptor:PROFILIN
Authors:Cedergren-Zeppezauer, E.S., Goonesekere, N.C.W., Rozycki, M.D., Myslik, J.C., Dauter, Z., Lindberg, U., Schutt, C.E.
Deposit date:1995-05-05
Release date:1995-07-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallization and structure determination of bovine profilin at 2.0 A resolution.
J.Mol.Biol., 240, 1994
2JKF
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PLASMODIUM FALCIPARUM PROFILIN
Descriptor:PROFILIN
Authors:Kursula, I., Kursula, P., Ganter, M., Panjikar, S., Matuschewski, K., Schueler, H.
Deposit date:2008-08-28
Release date:2008-09-23
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structural Basis for Parasite-Specific Functions of the Divergent Profilin of Plasmodium Falciparum
Structure, 16, 2008
2JKG
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PLASMODIUM FALCIPARUM PROFILIN
Descriptor:PROFILIN, OCTAPROLINE PEPTIDE, MAGNESIUM ION
Authors:Kursula, I., Kursula, P., Ganter, M., Panjikar, S., Matuschewski, K., Schueler, H.
Deposit date:2008-08-28
Release date:2008-09-23
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural Basis for Parasite-Specific Functions of the Divergent Profilin of Plasmodium Falciparum.
Structure, 16, 2008
2V8C
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MOUSE PROFILIN IIA IN COMPLEX WITH THE PROLINE-RICH DOMAIN OF VASP
Descriptor:PROFILIN-2, VASODILATOR-STIMULATED PHOSPHOPROTEIN, SULFATE ION, ...
Authors:Kursula, P., Downer, J., Witke, W., Wilmanns, M.
Deposit date:2007-08-06
Release date:2007-12-18
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:High-Resolution Structural Analysis of Mammalian Profilin 2A Complex Formation with Two Physiological Ligands: The Formin Homology 1 Domain of Mdia1 and the Proline-Rich Domain of Vasp.
J.Mol.Biol., 375, 2008
2V8F
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MOUSE PROFILIN IIA IN COMPLEX WITH A DOUBLE REPEAT FROM THE FH1 DOMAIN OF MDIA1
Descriptor:PROFILIN-2, PROTEIN DIAPHANOUS HOMOLOG 1, SULFATE ION, ...
Authors:Kursula, P., Kursula, I., Downer, J., Witke, W., Wilmanns, M.
Deposit date:2007-08-07
Release date:2007-12-18
Last modified:2012-11-21
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:High-Resolution Structural Analysis of Mammalian Profilin 2A Complex Formation with Two Physiological Ligands: The Formin Homology 1 Domain of Mdia1 and the Proline-Rich Domain of Vasp.
J.Mol.Biol., 375, 2008
2VK3
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CRYSTAL STRUCTURE OF RAT PROFILIN 2A
Descriptor:PROFILIN-2, (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, GLYCEROL, ...
Authors:Haikarainen, T., Kursula, P.
Deposit date:2007-12-17
Release date:2009-02-10
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure, Modifications and Ligand-Binding Properties of Rat Profilin 2A.
Acta Crystallogr.,Sect.D, 65, 2009
3D9Y
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CRYSTAL STRUCTURE OF PROFILIN FROM SCHIZOSACCHAROMYCES POMBE
Descriptor:Profilin, GLYCEROL
Authors:Ezezika, O.C., Nolen, B.J., Pollard, T.D.
Deposit date:2008-05-28
Release date:2008-12-16
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Incompatibility with Formin Cdc12p Prevents Human Profilin from Substituting for Fission Yeast Profilin: INSIGHTS FROM CRYSTAL STRUCTURES OF FISSION YEAST PROFILIN.
J.Biol.Chem., 284, 2009
3DAV
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SCHIZOSACCHAROMYCES POMBE PROFILIN CRYSTALLIZED FROM SODIUM FORMATE
Descriptor:Profilin, SODIUM ION
Authors:Ezezika, O.C., Nolen, B.J., Pollard, T.D.
Deposit date:2008-05-30
Release date:2008-12-16
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Incompatibility with Formin Cdc12p Prevents Human Profilin from Substituting for Fission Yeast Profilin: INSIGHTS FROM CRYSTAL STRUCTURES OF FISSION YEAST PROFILIN.
J.Biol.Chem., 284, 2009
3NEC
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CRYSTAL STRUCTURE OF TOXOPLASMA GONDII PROFILIN
Descriptor:Inflammatory profilin, (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, SULFATE ION
Authors:Kucera, K., Modis, Y.
Deposit date:2010-06-08
Release date:2010-09-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure-based analysis of Toxoplasma gondii profilin: a parasite-specific motif is required for recognition by Toll-like receptor 11.
J.Mol.Biol., 403, 2010
4D60
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STRUCTURE OF A DIMERIC PLASMODIUM FALCIPARUM PROFILIN MUTANT
Descriptor:PROFILIN, SULFATE ION
Authors:Bhargav, S.P., Vahokoski, J., Kallio, J.P., Torda, A., Kursula, P., Kursula, I.
Deposit date:2014-11-07
Release date:2015-06-03
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Two Independently Folding Units of Plasmodium Profilin Suggest Evolution Via Gene Fusion.
Cell.Mol.Life Sci., 72, 2015
4QWO
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1.52 ANGSTROM CRYSTAL STRUCTURE OF A42R PROFILIN-LIKE PROTEIN FROM MONKEYPOX VIRUS ZAIRE-96-I-16
Descriptor:Profilin, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, 1,2-ETHANEDIOL, ...
Authors:Minasov, G., Shuvalova, L., Dubrovska, I., Flores, K., Grimshaw, S., Kwon, K., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2014-07-16
Release date:2014-08-06
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:1.52 Angstrom Crystal Structure of A42R Profilin-like Protein from Monkeypox Virus Zaire-96-I-16.
TO BE PUBLISHED
4X1L
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STRUCTURAL BASIS FOR MUTATION-INDUCED DESTABILIZATION OF PROFILIN 1 IN ALS
Descriptor:Profilin-1, PHOSPHATE ION
Authors:Silvas, T.V., Shandilya, S.M.D., Schiffer, C.A.
Deposit date:2014-11-24
Release date:2015-06-10
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Structural basis for mutation-induced destabilization of profilin 1 in ALS.
Proc.Natl.Acad.Sci.USA, 112, 2015
4X1M
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STRUCTURAL BASIS FOR MUTATION-INDUCED DESTABILIZATION OF PROFILIN 1 IN ALS
Descriptor:Profilin-1
Authors:Silvas, T.V., Shandilya, S.M.D., Schiffer, C.A.
Deposit date:2014-11-24
Release date:2015-06-10
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structural basis for mutation-induced destabilization of profilin 1 in ALS.
Proc. Natl. Acad. Sci. U.S.A., 112, 2015
4X25
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STRUCTURAL BASIS FOR MUTATION-INDUCED DESTABILIZATION OF PROFILIN 1 IN ALS
Descriptor:Profilin-1
Authors:Silvas, T.V., Shandilya, S.M.D., Schiffer, C.A.
Deposit date:2014-11-25
Release date:2015-06-10
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structural basis for mutation-induced destabilization of profilin 1 in ALS.
Proc. Natl. Acad. Sci. U.S.A., 112, 2015
5FDS
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CRYSTAL STRUCTURE OF THE MONOMERIC ALLERGEN PROFILIN (HEV B 8)
Descriptor:Profilin-2, GLYCEROL, SULFATE ION
Authors:Mares-Mejia, I., Rodriguez-Romero, A.
Deposit date:2015-12-16
Release date:2016-09-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into the IgE mediated responses induced by the allergens Hev b 8 and Zea m 12 in their dimeric forms.
Sci Rep, 6, 2016
5FEF
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CRYSTAL STRUCTURE OF THE ALLERGEN PROFILIN (ZEA M 12)
Descriptor:Profilin-5, GLYCEROL
Authors:Mares-Mejia, I., Rodriguez-Romero, A.
Deposit date:2015-12-16
Release date:2016-09-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural insights into the IgE mediated responses induced by the allergens Hev b 8 and Zea m 12 in their dimeric forms.
Sci Rep, 6, 2016
5FEG
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CRYSTAL STRUCTURE OF THE DIMERIC ALLERGEN PROFILIN (HEV B 8)
Descriptor:Profilin-2
Authors:Mares-Mejia, I., Rodriguez-Romero, A.
Deposit date:2015-12-17
Release date:2016-09-14
Method:X-RAY DIFFRACTION (2.802 Å)
Cite:Structural insights into the IgE mediated responses induced by the allergens Hev b 8 and Zea m 12 in their dimeric forms.
Sci Rep, 6, 2016
5YED
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CRYSTAL STRUCTURE OF LOKIPROFILIN1
Descriptor:Uncharacterized protein
Authors:Robinson, R.C., Akil, C.
Deposit date:2017-09-16
Release date:2018-09-19
Last modified:2018-10-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Genomes of Asgard archaea encode profilins that regulate actin.
Nature, 562, 2018
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