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8X2U
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BU of 8x2u by Molmil
Radial spoke head-neck dimer
Descriptor: DPY30 domain containing 2, DnaJ homolog subfamily B member 13, Nucleoside diphosphate kinase homolog 5, ...
Authors:Meng, X, Cong, Y.
Deposit date:2023-11-10
Release date:2024-02-07
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:Multi-scale structures of the mammalian radial spoke and divergence of axonemal complexes in ependymal cilia.
Nat Commun, 15, 2024
8WZB
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BU of 8wzb by Molmil
RS head-neck monomer
Descriptor: DPY30 domain containing 2, DnaJ homolog subfamily B member 13, Nucleoside diphosphate kinase homolog 5, ...
Authors:Meng, X, Cong, Y.
Deposit date:2023-11-01
Release date:2024-02-07
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Multi-scale structures of the mammalian radial spoke and divergence of axonemal complexes in ependymal cilia.
Nat Commun, 15, 2024
8J07
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BU of 8j07 by Molmil
96nm repeat of human respiratory doublet microtubule and associated axonemal complexes
Descriptor: ACTA2, Axonemal dynein light intermediate polypeptide 1, Calaxin, ...
Authors:Gui, M, Brown, A.
Deposit date:2023-04-09
Release date:2023-07-26
Last modified:2023-08-02
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Axonemal structures reveal mechanoregulatory and disease mechanisms.
Nature, 618, 2023
8GLV
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BU of 8glv by Molmil
96-nm repeat unit of doublet microtubules from Chlamydomonas reinhardtii flagella
Descriptor: 28 kDa inner dynein arm light chain, axonemal, AAA+ ATPase domain-containing protein, ...
Authors:Walton, T, Brown, A.
Deposit date:2023-03-23
Release date:2023-05-31
Last modified:2023-06-28
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Axonemal structures reveal mechanoregulatory and disease mechanisms.
Nature, 618, 2023
8FEC
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BU of 8fec by Molmil
Structure of J-PKAc chimera complexed with Aplithianine derivative
Descriptor: 6-[(6P)-6-(4-bromo-1-methyl-1H-imidazol-5-yl)-2,3-dihydro-4H-1,4-thiazin-4-yl]-7H-purine, DnaJ homolog subfamily B member 1,cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha
Authors:Du, L, Wilson, B.A.P, Li, N, Martinez Fiesco, J.A, Dalilian, M, Wang, D, Smith, E.A, Wamiru, A, Goncharova, E.I, Zhang, P, O'Keefe, B.R.
Deposit date:2022-12-06
Release date:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structures of J-PKAc chimera complexed with Aplithianine and derivatives
To Be Published
8FE2
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BU of 8fe2 by Molmil
Structure of J-PKAc chimera complexed with Aplithianine A
Descriptor: 6-[(6M)-6-(1-methyl-1H-imidazol-5-yl)-2,3-dihydro-4H-1,4-thiazin-4-yl]-9H-purine, DnaJ homolog subfamily B member 1, cAMP-dependent protein kinase catalytic subunit alpha, ...
Authors:Du, L, Wilson, B.A.P, Li, N, Dalilian, M, Wang, D, Martinez Fiesco, J.A, Smith, E.A, Wamiru, A, Goncharova, E.I, Zhang, P, O'Keefe, B.R.
Deposit date:2022-12-05
Release date:2023-10-18
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Structures of J-PKAc chimera complexed with Aplithianine and derivatives
To Be Published
8FE5
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BU of 8fe5 by Molmil
Structure of J-PKAc chimera complexed with Aplithianine B
Descriptor: 6-[(6P)-6-(1-methyl-1H-imidazol-5-yl)-2,3-dihydro-4H-1,4-thiazin-4-yl]-7,9-dihydro-8H-purin-8-one, DnaJ homolog subfamily B member 1,cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha
Authors:Du, L, Wilson, B.A.P, Li, N, Martinez Fiesco, J.A, Dalilian, M, Wang, D, Smith, E.A, Wamiru, A, Goncharova, E.I, Zhang, P, O'Keefe, B.R.
Deposit date:2022-12-05
Release date:2023-10-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases.
J.Nat.Prod., 86, 2023
8BQS
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BU of 8bqs by Molmil
Cryo-EM structure of the I-II-III2-IV2 respiratory supercomplex from Tetrahymena thermophila
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2 iron, ...
Authors:Muhleip, A, Kock Flygaard, R, Baradaran, R, Amunts, A.
Deposit date:2022-11-21
Release date:2023-08-23
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of mitochondrial membrane bending by I-II-III2-IV2 supercomplex
To Be Published
8EOD
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BU of 8eod by Molmil
EEVD:Sis1-81 (J domain) bound conformation
Descriptor: Protein SIS1
Authors:Matos, C.O, Pinheiro, G.M.S, Ramos, C.H.I, Almeida, F.C.L.
Deposit date:2022-10-03
Release date:2023-10-18
Method:SOLUTION NMR
Cite:Structural and dynamical basis for the interaction of HSP70-EEVD with JDP Sis1
To Be Published
8GZU
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BU of 8gzu by Molmil
Cryo-EM structure of Tetrahymena thermophila respiratory Megacomplex MC (IV2+I+III2+II)2
Descriptor: 2 iron, 2 sulfur cluster-binding protein, 2-oxoglutarate/malate carrier protein, ...
Authors:Wu, M.C, Hu, Y.Q, Han, F.Z, Zhou, L.
Deposit date:2022-09-27
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (4.18 Å)
Cite:Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae.
Nat Commun, 14, 2023
8B6F
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BU of 8b6f by Molmil
Cryo-EM structure of NADH:ubiquinone oxidoreductase (complex-I) from respiratory supercomplex of Tetrahymena thermophila
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2 iron, ...
Authors:Muhleip, A, Kock Flygaard, R, Amunts, A.
Deposit date:2022-09-27
Release date:2023-03-29
Last modified:2023-04-12
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis of mitochondrial membrane bending by the I-II-III 2 -IV 2 supercomplex.
Nature, 615, 2023
8GYM
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BU of 8gym by Molmil
Cryo-EM structure of Tetrahymena thermophila respiratory mega-complex MC IV2+(I+III2+II)2
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ...
Authors:Wu, M.C, Hu, Y.Q, Han, F.Z, Zhou, L.
Deposit date:2022-09-23
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae.
Nat Commun, 14, 2023
8E2O
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BU of 8e2o by Molmil
Leveraging the Structure of DNAJA1 to Discover Novel Pancreatic Cancer Therapies
Descriptor: Isoform 2 of DnaJ homolog subfamily A member 1
Authors:Roth, H.E, Powers, R.
Deposit date:2022-08-15
Release date:2022-11-09
Method:SOLUTION NMR
Cite:Leveraging the Structure of DNAJA1 to Discover Novel Potential Pancreatic Cancer Therapies.
Biomolecules, 12, 2022
7ZHS
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BU of 7zhs by Molmil
3D reconstruction of the cylindrical assembly of DnaJA2 delta G/F by imposing D5 symmetry
Descriptor: Ubiquitin-like protein SMT3,DnaJ homolog subfamily A member 2, ZINC ION
Authors:Cuellar, J, Velasco-Carneros, L, Santiago, C, Martin-Benito, J, Valpuesta, J, Muga, A.
Deposit date:2022-04-07
Release date:2023-07-26
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (6.9 Å)
Cite:The self-association equilibrium of DNAJA2 regulates its interaction with unfolded substrate proteins and with Hsc70.
Nat Commun, 14, 2023
7X89
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BU of 7x89 by Molmil
Tid1
Descriptor: DnaJ homolog subfamily A member 3, mitochondrial
Authors:Jang, J, Lee, S.H, Kang, D.H, Sim, D.W, Jo, K.S, Ryu, H, Kim, E.H, Ryu, K.S, Lee, J.H, Kim, J.H, Won, H.S.
Deposit date:2022-03-11
Release date:2023-03-22
Method:SOLUTION NMR
Cite:Structural studies on the J-domain and GF-motif of the mitochondrial Hsp40, Tid1
To Be Published
7Z3N
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BU of 7z3n by Molmil
Cryo-EM structure of the ribosome-associated RAC complex on the 80S ribosome - RAC-1 conformation
Descriptor: 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ...
Authors:Kisonaite, M, Wild, K, Sinning, I.
Deposit date:2022-03-02
Release date:2023-04-12
Last modified:2023-05-31
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural inventory of cotranslational protein folding by the eukaryotic RAC complex.
Nat.Struct.Mol.Biol., 30, 2023
7Z3O
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BU of 7z3o by Molmil
Cryo-EM structure of the ribosome-associated RAC complex on the 80S ribosome - RAC-2 conformation
Descriptor: 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ...
Authors:Kisonaite, M, Wild, K, Sinning, I.
Deposit date:2022-03-02
Release date:2023-04-12
Last modified:2023-05-31
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural inventory of cotranslational protein folding by the eukaryotic RAC complex.
Nat.Struct.Mol.Biol., 30, 2023
7X3K
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BU of 7x3k by Molmil
Cryo-EM structure of RAC in the State C2 RNC-RAC complex
Descriptor: Ribosome-associated complex subunit SSZ1, Zuotin
Authors:Chen, Y, Gao, N.
Deposit date:2022-03-01
Release date:2022-06-29
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structural remodeling of ribosome associated Hsp40-Hsp70 chaperones during co-translational folding.
Nat Commun, 13, 2022
7TGH
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BU of 7tgh by Molmil
Cryo-EM structure of respiratory super-complex CI+III2 from Tetrahymena thermophila
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2 iron, ...
Authors:Zhou, L, Maldonado, M, Padavannil, A, Guo, F, Letts, J.A.
Deposit date:2022-01-07
Release date:2022-04-06
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structures of Tetrahymena 's respiratory chain reveal the diversity of eukaryotic core metabolism.
Science, 376, 2022
7VPX
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BU of 7vpx by Molmil
The cryo-EM structure of the human pre-A complex
Descriptor: 5SS, DnaJ homolog subfamily C member 8, PHD finger-like domain-containing protein 5A, ...
Authors:Zhang, X, Zhan, X, Shi, Y.
Deposit date:2021-10-18
Release date:2023-05-03
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Mechanism for Branch Site Recognition and Proofreading During Prespliceosome Assembly
To Be Published
7AOI
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BU of 7aoi by Molmil
Trypanosoma brucei mitochondrial ribosome large subunit assembly intermediate
Descriptor: 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L17, ...
Authors:Tobiasson, V, Gahura, O, Aibara, S, Baradaran, R, Zikova, A, Amunts, A.
Deposit date:2020-10-14
Release date:2020-12-02
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Interconnected assembly factors regulate the biogenesis of mitoribosomal large subunit.
Embo J., 40, 2021
7AM2
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BU of 7am2 by Molmil
Intermediate assembly of the Large subunit from Leishmania major mitochondrial ribosome
Descriptor: 50S ribosomal protein L13-like protein, ADENOSINE-5'-TRIPHOSPHATE, Acyl carrier protein, ...
Authors:Soufari, H, Waltz, F, Parrot, C, Bochler, A, Hashem, Y.
Deposit date:2020-10-07
Release date:2021-04-28
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis.
Proc.Natl.Acad.Sci.USA, 117, 2020
7KAO
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BU of 7kao by Molmil
Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore mutant, class without Sec62
Descriptor: Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ...
Authors:Itskanov, S, Park, E.
Deposit date:2020-10-01
Release date:2021-02-03
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62.
Nat.Struct.Mol.Biol., 28, 2021
7KAQ
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BU of 7kaq by Molmil
Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore mutant, class with Sec62, conformation 2 (C2)
Descriptor: Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ...
Authors:Itskanov, S, Park, E.
Deposit date:2020-10-01
Release date:2021-01-06
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62.
Nat.Struct.Mol.Biol., 28, 2021
7KAS
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BU of 7kas by Molmil
Cryo-EM structure of the Sec complex from S. cerevisiae, Sec63 FN3 mutant, class with Sec62
Descriptor: Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ...
Authors:Itskanov, S, Park, E.
Deposit date:2020-10-01
Release date:2021-01-06
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62.
Nat.Struct.Mol.Biol., 28, 2021

 

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PDB entries from 2024-03-27

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