8HD5
 
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8FLJ
 | | Cas1-Cas2/3 integrase and IHF bound to CRISPR leader, repeat and foreign DNA | | Descriptor: | CRISPR leader and repeat, anti-sense strand of DNA, CRISPR leader, ... | | Authors: | Santiago-Frangos, A, Henriques, W.S, Wiegand, T, Gauvin, C, Buyukyoruk, M, Neselu, K, Eng, E.T, Lander, G.C, Wiedenheft, B. | | Deposit date: | 2022-12-21 | | Release date: | 2023-09-06 | | Last modified: | 2023-11-22 | | Method: | ELECTRON MICROSCOPY (3.48 Å) | | Cite: | Structure reveals why genome folding is necessary for site-specific integration of foreign DNA into CRISPR arrays.
Nat.Struct.Mol.Biol., 30, 2023
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6OAJ
 | | HUaE34K 19bp SYM DNA | | Descriptor: | DNA (5'-D(P*CP*GP*GP*TP*TP*CP*AP*AP*TP*TP*GP*GP*CP*AP*CP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*CP*GP*TP*GP*CP*CP*AP*AP*TP*TP*GP*AP*AP*CP*CP*GP*C)-3'), DNA-binding protein HU-alpha | | Authors: | Remesh, S.G, Hammel, M. | | Deposit date: | 2019-03-16 | | Release date: | 2020-03-18 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (4.092 Å) | | Cite: | Nucleoid remodeling during environmental adaptation is regulated by HU-dependent DNA bundling.
Nat Commun, 11, 2020
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6O8Q
 | | HUaa 19bp SYM DNA pH 4.5 | | Descriptor: | DNA (57-MER), DNA-binding protein HU-alpha | | Authors: | Remesh, S.G, Hammel, M. | | Deposit date: | 2019-03-11 | | Release date: | 2020-03-18 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.216 Å) | | Cite: | Nucleoid remodeling during environmental adaptation is regulated by HU-dependent DNA bundling.
Nat Commun, 11, 2020
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6O6K
 | | HUaa 19bp SYM DNA pH 5.5 | | Descriptor: | DNA (5'-D(P*AP*TP*TP*TP*CP*AP*TP*GP*AP*T)-3'), DNA (5'-D(P*CP*AP*TP*CP*AP*TP*GP*AP*AP*A)-3'), DNA-binding protein HU-alpha | | Authors: | Remesh, S.G, Hammel, M. | | Deposit date: | 2019-03-06 | | Release date: | 2020-03-11 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.601 Å) | | Cite: | Nucleoid remodeling during environmental adaptation is regulated by HU-dependent DNA bundling.
Nat Commun, 11, 2020
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6N2L
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6LMJ
 | | ASFV pA104R in complex with double-strand DNA | | Descriptor: | A104R, DNA (5'-D(*TP*GP*CP*TP*TP*AP*TP*CP*AP*AP*TP*TP*TP*GP*TP*TP*GP*CP*A)-3') | | Authors: | Wang, H, Qi, J, Chai, Y, Gao, F, Liu, R. | | Deposit date: | 2019-12-25 | | Release date: | 2020-05-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The structural basis of African swine fever virus pA104R binding to DNA and its inhibition by stilbene derivatives.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6LMH
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5WFE
 | | Cas1-Cas2-IHF-DNA holo-complex | | Descriptor: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (28-MER), ... | | Authors: | Wright, A.V, Liu, J.J, Nogales, E, Doudna, J.A. | | Deposit date: | 2017-07-11 | | Release date: | 2017-08-02 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.64 Å) | | Cite: | Structures of the CRISPR genome integration complex.
Science, 357, 2017
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5LVT
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5J0N
 | | Lambda excision HJ intermediate | | Descriptor: | Excisionase, Integrase, Integration host factor subunit alpha, ... | | Authors: | Van Duyne, G, Grigorieff, N, Landy, A. | | Deposit date: | 2016-03-28 | | Release date: | 2017-02-08 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (11 Å) | | Cite: | Structure of a Holliday junction complex reveals mechanisms governing a highly regulated DNA transaction.
Elife, 5, 2016
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5FBM
 | | Crystal Structure of Histone Like Protein (HLP) from Streptococcus mutans Refined to 1.9 A Resolution | | Descriptor: | DNA-binding protein HU | | Authors: | Lovell, S, Battaile, K.P, Mehzabeen, N, O'Neil, P, Biswas, I. | | Deposit date: | 2015-12-14 | | Release date: | 2016-04-06 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of histone-like protein from Streptococcus mutans refined to 1.9 angstrom resolution.
Acta Crystallogr F Struct Biol Commun, 72, 2016
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5EKA
 | | HU DNA-binding protein from Thermus thermophilus | | Descriptor: | DNA-binding protein HU, GLYCEROL | | Authors: | Papageorgiou, A, Adam, P, Stavros, P, Nounesis, G, Meijers, R, Petratos, K, Vorgias, C.E. | | Deposit date: | 2015-11-03 | | Release date: | 2016-07-06 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | HU histone-like DNA-binding protein from Thermus thermophilus: structural and evolutionary analyses.
Extremophiles, 20, 2016
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4YFT
 | | HUab-20bp | | Descriptor: | DNA-binding protein HU-alpha, DNA-binding protein HU-beta, synthetic DNA strand | | Authors: | Hammel, M, Reyes, F.E, Parpana, R, Tainer, J.A, Adhya, S, Amlanjyoti, D. | | Deposit date: | 2015-02-25 | | Release date: | 2016-06-29 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.914 Å) | | Cite: | HU multimerization shift controls nucleoid compaction.
Sci Adv, 2, 2016
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4YFH
 | | HU38-20bp | | Descriptor: | DNA-binding protein HU-alpha, synthetic DNA strand | | Authors: | Hammel, M, Reyes, F.E, Parpana, R, Tainer, J.A, Adhya, S, Amlanjyoti, D. | | Deposit date: | 2015-02-25 | | Release date: | 2016-06-29 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.49 Å) | | Cite: | HU multimerization shift controls nucleoid compaction.
Sci Adv, 2, 2016
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4YF0
 | | HU38-19bp | | Descriptor: | DNA-binding protein HU-alpha, synthetic DNA strand | | Authors: | Hammel, M, Reyes, F.E, Parpana, R, Tainer, J.A, Adhya, S, Amlanjyoti, D. | | Deposit date: | 2015-02-24 | | Release date: | 2016-06-29 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | HU multimerization shift controls nucleoid compaction.
Sci Adv, 2, 2016
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4YEY
 | | HUaa-20bp | | Descriptor: | DNA-binding protein HU-alpha, synthetic DNA strand | | Authors: | Hammel, M, Reyes, F.E, Parpana, R, Tainer, J.A, Adhya, S, Amlanjyoti, D. | | Deposit date: | 2015-02-24 | | Release date: | 2016-06-29 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.354 Å) | | Cite: | HU multimerization shift controls nucleoid compaction.
Sci Adv, 2, 2016
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4YEX
 | | HUaa-19bp | | Descriptor: | DNA-binding protein HU-alpha, synthetic DNA strand | | Authors: | Hammel, M, Reyes, F.E, Parpana, R, Tainer, J.A, Adhya, S, Amlanjyoti, D. | | Deposit date: | 2015-02-24 | | Release date: | 2016-06-29 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | HU multimerization shift controls nucleoid compaction.
Sci Adv, 2, 2016
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4YEW
 | | HUab-19bp | | Descriptor: | DNA-binding protein HU-alpha, DNA-binding protein HU-beta, synthetic DNA strand | | Authors: | Hammel, M, Reyes, F.E, Parpana, R, Tainer, J.A, Adhya, S, Amlanjyoti, D. | | Deposit date: | 2015-02-24 | | Release date: | 2016-06-29 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.683 Å) | | Cite: | HU multimerization shift controls nucleoid compaction.
Sci Adv, 2, 2016
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4QJU
 | | Crystal structure of DNA-bound nucleoid associated protein, SAV1473 | | Descriptor: | DNA (5'-D(*TP*GP*CP*TP*TP*AP*TP*CP*AP*AP*TP*TP*TP*GP*TP*TP*GP*CP*AP*CP*C)-3'), DNA-binding protein HU | | Authors: | Lee, B.-J, Kim, D.-H, Im, H, Yoon, H.-J. | | Deposit date: | 2014-06-04 | | Release date: | 2014-12-17 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.16 Å) | | Cite: | beta-Arm flexibility of HU from Staphylococcus aureus dictates the DNA-binding and recognition mechanism
Acta Crystallogr.,Sect.D, 70, 2014
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4QJN
 | | Crystal structure of apo nucleoid associated protein, SAV1473 | | Descriptor: | DNA-binding protein HU | | Authors: | Lee, B.-J, Kim, D.-H, Im, H, Yoon, H.-J. | | Deposit date: | 2014-06-04 | | Release date: | 2014-12-17 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.613 Å) | | Cite: | beta-Arm flexibility of HU from Staphylococcus aureus dictates the DNA-binding and recognition mechanism
Acta Crystallogr.,Sect.D, 70, 2014
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4PT4
 | | Crystal structure Analysis of N terminal region containing the dimerization domain and DNA binding domain of HU protein(Histone like protein-DNA binding) from Mycobacterium tuberculosis [H37Ra] | | Descriptor: | DNA-binding protein HU homolog, FORMIC ACID | | Authors: | Bhowmick, T, Ramagopal, U.A, Ghosh, S, Nagaraja, V, Ramakumar, S. | | Deposit date: | 2014-03-10 | | Release date: | 2014-05-21 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Targeting Mycobacterium tuberculosis nucleoid-associated protein HU with structure-based inhibitors
Nat Commun, 5, 2014
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4P3V
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4DKY
 | | Crystal structure Analysis of N terminal region containing the dimerization domain and DNA binding domain of HU protein(Histone like protein-DNA binding) from Mycobacterium tuberculosis [H37Ra] | | Descriptor: | DNA-binding protein HU homolog, MANGANESE (II) ION | | Authors: | Bhowmick, T, Ramagopal, U.A, Ghosh, S, Nagaraja, V, Ramakumar, S. | | Deposit date: | 2012-02-05 | | Release date: | 2013-02-06 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.478 Å) | | Cite: | Targeting Mycobacterium tuberculosis nucleoid-associated protein HU with structure-based inhibitors
Nat Commun, 5, 2014
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3RHI
 | | DNA-binding protein HU from Bacillus anthracis | | Descriptor: | DNA-binding protein HU | | Authors: | Osipiuk, J, Makowska-Grzyska, M, Hasseman, J, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2011-04-11 | | Release date: | 2011-04-20 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.48 Å) | | Cite: | DNA-binding protein HU from Bacillus anthracis.
To be Published
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