1AB8
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RAT TYPE II ADENYLYL CYCLASE C2 DOMAIN/FORSKOLIN COMPLEX
Descriptor:ADENYLYL CYCLASE, FORSKOLIN
Authors:Zhang, G., Hurley, J.H.
Deposit date:1997-02-04
Release date:1997-05-15
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the adenylyl cyclase catalytic core.
Nature, 386, 1997
1FX2
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STRUCTURAL ANALYSIS OF ADENYLATE CYCLASES FROM TRYPANOSOMA BRUCEI IN THEIR MONOMERIC STATE
Descriptor:RECEPTOR-TYPE ADENYLATE CYCLASE GRESAG 4.1, SULFATE ION, 2,3-DIHYDROXY-1,4-DITHIOBUTANE
Authors:Bieger, B., Essen, L.-O.
Deposit date:2000-09-25
Release date:2001-02-28
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Structural analysis of adenylate cyclases from Trypanosoma brucei in their monomeric state.
EMBO J., 20, 2001
1FX4
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STRUCTURE ANALYSIS OF ADENYLATE CYCLASES FROM TRYPANOSOMA BRUCEI IN THEIR MONOMERIC STATE
Descriptor:RECEPTOR-TYPE ADENYLATE CYCLASE GRESAG 4.3, MAGNESIUM ION
Authors:Bieger, B., Essen, L.O.
Deposit date:2000-09-25
Release date:2001-02-28
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of adenylate cyclases from Trypanosoma brucei in their monomeric state.
EMBO J., 20, 2001
1WC0
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SOLUBLE ADENYLYL CYCLASE CYAC FROM S. PLATENSIS IN COMPLEX WITH ALPHA, BETA-METHYLENE-ATP
Descriptor:ADENYLATE CYCLASE, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, CALCIUM ION
Authors:Steegborn, C., Litvin, T.N., Levin, L.R., Buck, J., Wu, H.
Deposit date:2004-11-05
Release date:2004-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Bicarbonate Activation of Adenylyl Cyclase Via Promotion of Catalytic Active Site Closure and Metal Recruitment
Nat.Struct.Mol.Biol., 12, 2005
1WC1
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SOLUBLE ADENYLYL CYCLASE CYAC FROM S. PLATENSIS IN COMPLEX WITH RP- ATPALPHAS
Descriptor:ADENYLATE CYCLASE, ADENOSINE-5'-RP-ALPHA-THIO-TRIPHOSPHATE, MAGNESIUM ION
Authors:Steegborn, C., Litvin, T.N., Levin, L.R., Buck, J., Wu, H.
Deposit date:2004-11-06
Release date:2004-12-20
Last modified:2013-02-06
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Bicarbonate Activation of Adenylyl Cyclase Via Promotion of Catalytic Active Site Closure and Metal Recruitment
Nat.Struct.Mol.Biol., 12, 2005
1WC3
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SOLUBLE ADENYLYL CYCLASE CYAC FROM S. PLATENSIS IN COMPLEX WITH ALPHA, BETA-METHYLENE-ATP AND STRONTIUM
Descriptor:ADENYLATE CYCLASE, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, STRONTIUM ION
Authors:Steegborn, C., Litvin, T.N., Levin, L.R., Buck, J., Wu, H.
Deposit date:2004-11-08
Release date:2004-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Bicarbonate Activation of Adenylyl Cyclase Via Promotion of Catalytic Active Site Closure and Metal Recruitment
Nat.Struct.Mol.Biol., 12, 2005
1WC4
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SOLUBLE ADENYLYL CYCLASE CYAC FROM S. PLATENSIS IN COMPLEX WITH ALPHA, BETA-METHYLENE-ATP AND EUROPIUM
Descriptor:ADENYLATE CYCLASE, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, EUROPIUM (III) ION
Authors:Steegborn, C., Litvin, T.N., Levin, L.R., Buck, J., Wu, H.
Deposit date:2004-11-08
Release date:2004-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Bicarbonate Activation of Adenylyl Cyclase Via Promotion of Catalytic Active Site Closure and Metal Recruitment
Nat.Struct.Mol.Biol., 12, 2005
1WC5
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SOLUBLE ADENYLYL CYCLASE CYAC FROM S. PLATENSIS IN COMPLEX WITH ALPHA, BETA-METHYLENE-ATP IN PRESENCE OF BICARBONATE
Descriptor:ADENYLATE CYCLASE, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION, ...
Authors:Steegborn, C., Litvin, T.N., Levin, L.R., Buck, J., Wu, H.
Deposit date:2004-11-08
Release date:2004-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Bicarbonate Activation of Adenylyl Cyclase Via Promotion of Catalytic Active Site Closure and Metal Recruitment
Nat.Struct.Mol.Biol., 12, 2005
1WC6
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SOLUBLE ADENYLYL CYCLASE CYAC FROM S. PLATENSIS IN COMPLEX WITH RP- ATPALPHAS IN PRESENCE OF BICARBONATE
Descriptor:ADENYLATE CYCLASE, ADENOSINE-5'-RP-ALPHA-THIO-TRIPHOSPHATE, MAGNESIUM ION
Authors:Steegborn, C., Litvin, T.N., Levin, L.R., Buck, J., Wu, H.
Deposit date:2004-11-08
Release date:2004-12-20
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Bicarbonate Activation of Adenylyl Cyclase Via Promotion of Catalytic Active Site Closure and Metal Recruitment
Nat.Struct.Mol.Biol., 12, 2005
1YBT
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MYCOBACTERIUM TUBERCULOSIS ADENYLYL CYCLASE, RV1900C CHD
Descriptor:hydrolase, alpha/beta hydrolase fold family
Authors:Sinha, S.C., Wetterer, M., Sprang, S.R., Schultz, J.E., Linder, J.U.
Deposit date:2004-12-21
Release date:2005-02-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Origin of asymmetry in adenylyl cyclases: structures of Mycobacterium tuberculosis Rv1900c.
Embo J., 24, 2005
1YBU
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MYCOBACTERIUM TUBERCULOSIS ADENYLYL CYCLASE RV1900C CHD, IN COMPLEX WITH A SUBSTRATE ANALOG.
Descriptor:lipJ, MANGANESE (II) ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER
Authors:Sinha, S.C., Wetterer, M., Sprang, S.R., Schultz, J.E., Linder, J.U.
Deposit date:2004-12-21
Release date:2005-02-15
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Origin of asymmetry in adenylyl cyclases: structures of Mycobacterium tuberculosis Rv1900c.
Embo J., 24, 2005
1YK9
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CRYSTAL STRUCTURE OF A MUTANT FORM OF THE MYCOBACTERIAL ADENYLYL CYCLASE RV1625C
Descriptor:Adenylate cyclase
Authors:Ketkar, A.D., Shenoy, A.R., Ramagopal, U.A., Visweswariah, S.S., Suguna, K., TB Structural Genomics Consortium (TBSGC)
Deposit date:2005-01-17
Release date:2006-01-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A Structural Basis for the Role of Nucleotide Specifying Residues in Regulating the Oligomerization of the Rv1625c Adenylyl Cyclase from M.tuberculosis
J.Mol.Biol., 356, 2006
2BW7
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A NOVEL MECHANISM FOR ADENYLYL CYCLASE INHIBITION FROM THE CRYSTAL STRUCTURE OF ITS COMPLEX WITH CATECHOL ESTROGEN
Descriptor:ADENYLATE CYCLASE, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION, ...
Authors:Steegborn, C., Litvin, T.N., Hess, K.C., Capper, A.B., Taussig, R., Buck, J., Levin, L.R., Wu, H.
Deposit date:2005-07-12
Release date:2005-07-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A Novel Mechanism for Adenylyl Cyclase Inhibition from the Crystal Structure of its Complex with Catechol Estrogen
J.Biol.Chem., 280, 2005
2W01
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CRYSTAL STRUCTURE OF THE GUANYLYL CYCLASE CYA2
Descriptor:ADENYLATE CYCLASE
Authors:Rauch, A., Leipelt, M., Russwurm, M., Steegborn, C.
Deposit date:2008-08-08
Release date:2008-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Crystal Structure of the Guanylyl Cyclase Cya2.
Proc.Natl.Acad.Sci.USA, 105, 2008
2WZ1
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STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN SOLUBLE GUANYLATE CYCLASE 1 BETA 3.
Descriptor:GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-1, 1,2-ETHANEDIOL
Authors:Allerston, C.K., Cooper, C.D.O., Muniz, J., Pike, A.C.W., von Delft, F., Arrowsmith, C.H., Weigelt, J., Edwards, A., Bountra, C., Gileadi, O.
Deposit date:2009-11-23
Release date:2009-12-01
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Crystal Structures of the Catalytic Domain of Human Soluble Guanylate Cyclase.
Plos One, 8, 2013
3ET6
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THE CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF A EUKARYOTIC GUANYLATE CYCLASE
Descriptor:Soluble guanylyl cyclase beta, PHOSPHATE ION
Authors:Winger, J.A., Derbyshire, E.R., Lamers, M.H., Marletta, M.A., Kuriyan, J.
Deposit date:2008-10-07
Release date:2008-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase.
Bmc Struct.Biol., 8, 2008
3MR7
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CRYSTAL STRUCTURE OF ADENYLATE/GUANYLATE CYCLASE/HYDROLASE FROM SILICIBACTER POMEROYI
Descriptor:Adenylate/guanylate cyclase/hydrolase, alpha/beta fold family
Authors:Kim, Y., Li, H., Clancy, S., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2010-04-28
Release date:2010-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of Adenylate/Guanylate Cyclase/Hydrolase from Silicibacter pomeroyi
To be Published
3R5G
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CRYSTAL STRUCTURE OF THE ADENYLYL CYCLASE CYAB FROM P. AERUGINOSA
Descriptor:CyaB, GLYCEROL
Authors:Topal, H., Steegborn, C.
Deposit date:2011-03-18
Release date:2012-01-11
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure and Regulation Mechanisms of the CyaB Adenylyl Cyclase from the Human Pathogen Pseudomonas aeruginosa.
J.Mol.Biol., 416, 2012
3UVJ
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THE HETERODIMERIC HUMAN SOLUBLE GUANYLATE CYCLASE 1.
Descriptor:Guanylate cyclase soluble subunit alpha-3, Guanylate cyclase soluble subunit beta-1, 1,2-ETHANEDIOL, ...
Authors:Allerston, C.K., Berridge, G., Chalk, R., Cooper, C.D.O., Savitsky, P., Vollmar, M., Arrowsmith, C.H., Weigelt, J., Edwards, A., Bountra, C., von Delft, F., Gileadi, O., Structural Genomics Consortium (SGC)
Deposit date:2011-11-30
Release date:2011-12-28
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Crystal structures of the catalytic domain of human soluble guanylate cyclase.
Plos One, 8, 2013
4CLF
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CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLYL CYCLASE (APO FORM)
Descriptor:ADENYLATE CYCLASE TYPE 10, ACETATE ION, GLYCEROL
Authors:Kleinboelting, S., Moniot, S., Weyand, M., Steegborn, C.
Deposit date:2014-01-14
Release date:2014-03-05
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structures of Human Soluble Adenylyl Cyclase Reveal Mechanisms of Catalysis and of its Activation Through Bicarbonate.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CLK
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CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLYL CYCLASE IN COMPLEX WITH ALPHA,BETA-METHYLENEADENOSINE-5'-TRIPHOSPHATE
Descriptor:ADENYLATE CYCLASE TYPE 10, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, CHLORIDE ION, ...
Authors:Kleinboelting, S., Weyand, M., Steegborn, C.
Deposit date:2014-01-15
Release date:2014-03-05
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structures of Human Soluble Adenylyl Cyclase Reveal Mechanisms of Catalysis and of its Activation Through Bicarbonate.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CLL
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CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLYL CYCLASE IN COMPLEX WITH BICARBONATE
Descriptor:ADENYLATE CYCLASE TYPE 10, BICARBONATE ION, 1,2-ETHANEDIOL, ...
Authors:Kleinboelting, S., Weyand, M., Steegborn, C.
Deposit date:2014-01-15
Release date:2014-03-05
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structures of Human Soluble Adenylyl Cyclase Reveal Mechanisms of Catalysis and of its Activation Through Bicarbonate.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CLP
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CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLYL CYCLASE COMPLEX WITH ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE
Descriptor:ADENYLATE CYCLASE TYPE 10, ACETATE ION, GLYCEROL, ...
Authors:Kleinboelting, S., Weyand, M., Steegborn, C.
Deposit date:2014-01-15
Release date:2014-03-05
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structures of Human Soluble Adenylyl Cyclase Reveal Mechanisms of Catalysis and of its Activation Through Bicarbonate.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CLS
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CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLYL CYCLASE WITH PYROPHOSPHATE
Descriptor:ADENYLATE CYCLASE TYPE 10, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Kleinboelting, S., Weyand, M., Steegborn, C.
Deposit date:2014-01-15
Release date:2014-03-05
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structures of Human Soluble Adenylyl Cyclase Reveal Mechanisms of Catalysis and of its Activation Through Bicarbonate.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CLT
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CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLYL CYCLASE WITH ADENOSINE-3', 5'-CYCLIC-MONOPHOSPHATE AND PYROPHOSPHATE
Descriptor:ADENYLATE CYCLASE TYPE 10, MAGNESIUM ION, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ...
Authors:Kleinboelting, S., Weyand, M., Steegborn, C.
Deposit date:2014-01-15
Release date:2014-03-05
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structures of Human Soluble Adenylyl Cyclase Reveal Mechanisms of Catalysis and of its Activation Through Bicarbonate.
Proc.Natl.Acad.Sci.USA, 111, 2014
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