6DQG
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HUMAN GLUTAMATE DEHYDROGENASE, H454Y MUTANT
Descriptor:Glutamate dehydrogenase 1, mitochondrial, PHOSPHATE ION
Authors:Smith, T.J.
Deposit date:2018-06-10
Release date:2018-06-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Consequences of Sequence Errors in Bovine Glutamate Dehydrogenase: Insights into a Promiscuous Allosteric Regulatory Site.
To be Published
6DHQ
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BOVINE GLUTAMATE DEHYDROGENASE COMPLEXED WITH NADPH, GLUTAMATE, AND GTP
Descriptor:Glutamate dehydrogenase 1, mitochondrial, GLUTAMIC ACID, ...
Authors:Smith, T.J.
Deposit date:2018-05-20
Release date:2018-07-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation.
J. Mol. Biol., 307, 2001
6DHN
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BOVINE GLUTAMATE DEHYDROGENASE COMPLEXED WITH EU3+
Descriptor:Glutamate dehydrogenase 1, mitochondrial, GLUTAMIC ACID, ...
Authors:Smith, T.J.
Deposit date:2018-05-20
Release date:2018-07-25
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A novel mechanism of V-type zinc inhibition of glutamate dehydrogenase results from disruption of subunit interactions necessary for efficient catalysis.
FEBS J., 278, 2011
6DHM
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BOVINE GLUTAMATE DEHYDROGENASE COMPLEXED WITH ZINC
Descriptor:Glutamate dehydrogenase 1, mitochondrial, GLUTAMIC ACID, ...
Authors:Smith, T.J.
Deposit date:2018-05-20
Release date:2018-07-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:A novel mechanism of V-type zinc inhibition of glutamate dehydrogenase results from disruption of subunit interactions necessary for efficient catalysis.
FEBS J., 278, 2011
6DHL
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BOVINE GLUTAMATE DEHYDROGENASE COMPLEXED WITH EPICATECHIN-3-GALLATE (ECG)
Descriptor:Glutamate dehydrogenase 1, mitochondrial, (2R,3S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate
Authors:Smith, T.J.
Deposit date:2018-05-20
Release date:2018-07-25
Method:X-RAY DIFFRACTION (3.624 Å)
Cite:Green tea polyphenols control dysregulated glutamate dehydrogenase in transgenic mice by hijacking the ADP activation site.
J. Biol. Chem., 286, 2011
6DHK
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BOVINE GLUTAMATE DEHYDROGENASE COMPLEXED WITH ADP
Descriptor:Glutamate dehydrogenase 1, mitochondrial, ADENOSINE-5'-DIPHOSPHATE
Authors:Smith, T.J.
Deposit date:2018-05-20
Release date:2018-07-25
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural studies on ADP activation of mammalian glutamate dehydrogenase and the evolution of regulation.
Biochemistry, 42, 2003
6DHD
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BOVINE GLUTAMATE DEHYDROGENASE COMPLEXED WITH NADH, GTP, GLUTAMATE
Descriptor:Glutamate dehydrogenase 1, mitochondrial, GLUTAMIC ACID, ...
Authors:Smith, T.J.
Deposit date:2018-05-19
Release date:2018-07-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation.
J. Mol. Biol., 307, 2001
5XWC
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CRYSTAL STRUCTURE OF ASPERGILLUS NIGER GLUTAMATE DEHYDROGENASE COMPLEXED WITH ALPHA-IMINOGLUTARATE, 2-AMINO-2-HYDROXYGLUTARATE AND NADP
Descriptor:Glutamate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (2S)-2-azanyl-2-oxidanyl-pentanedioic acid, ...
Authors:Prakash, P., Punekar, N.S., Bhaumik, P.
Deposit date:2017-06-29
Release date:2018-03-21
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for the catalytic mechanism and alpha-ketoglutarate cooperativity of glutamate dehydrogenase.
J. Biol. Chem., 293, 2018
5XW0
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CRYSTAL STRUCTURE OF ASPERGILLUS NIGER GLUTAMATE DEHYDROGENASE COMPLEXED WITH ISOPHTHALATE AND NADPH
Descriptor:Glutamate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, benzene-1,3-dicarboxylic acid, ...
Authors:Prakash, P., Punekar, N.S., Bhaumik, P.
Deposit date:2017-06-28
Release date:2018-03-21
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for the catalytic mechanism and alpha-ketoglutarate cooperativity of glutamate dehydrogenase.
J. Biol. Chem., 293, 2018
5XVX
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CRYSTAL STRUCTURE OF ASPERGILLUS NIGER GLUTAMATE DEHYDROGENASE COMPLEXED WITH ALPHA-KETOGLUTARATE AND NADPH
Descriptor:Glutamate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-OXOGLUTARIC ACID, ...
Authors:Prakash, P., Punekar, N.S., Bhaumik, P.
Deposit date:2017-06-28
Release date:2018-03-21
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for the catalytic mechanism and alpha-ketoglutarate cooperativity of glutamate dehydrogenase.
J. Biol. Chem., 293, 2018
5XVV
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CRYSTAL STRUCTURE OF FORWARD INHIBITED ASPERGILLUS NIGER GLUTAMATE DEHYDROGENASE WITH BOTH APO- AND ALPHA KETOGLUTARATE BOUND SUBUNITS
Descriptor:Glutamate dehydrogenase, GLYCEROL, 2-OXOGLUTARIC ACID, ...
Authors:Prakash, P., Punekar, N.S., Bhaumik, P.
Deposit date:2017-06-28
Release date:2018-03-21
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for the catalytic mechanism and alpha-ketoglutarate cooperativity of glutamate dehydrogenase.
J. Biol. Chem., 293, 2018
5XVI
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CRYSTAL STRUCTURE OF ASPERGILLUS NIGER APO- GLUTAMATE DEHYDROGENASE
Descriptor:Glutamate dehydrogenase, GLYCEROL
Authors:Prakash, P., Punekar, N.S., Bhaumik, P.
Deposit date:2017-06-28
Release date:2018-03-21
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for the catalytic mechanism and alpha-ketoglutarate cooperativity of glutamate dehydrogenase.
J. Biol. Chem., 293, 2018
5K12
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CRYO-EM STRUCTURE OF GLUTAMATE DEHYDROGENASE AT 1.8 A RESOLUTION
Descriptor:Glutamate dehydrogenase 1, mitochondrial
Authors:Merk, A., Bartesaghi, A., Banerjee, S., Falconieri, V., Rao, P., Earl, L., Milne, J., Subramaniam, S.
Deposit date:2016-05-17
Release date:2016-06-08
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (1.8 Å)
Cite:Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery.
Cell, 165, 2016
5IJZ
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CRYSTAL STRCUTURE OF GLUTAMATE DEHYDROGENASE(GDH) FROM CORYNEBACTERIUM GLUTAMICUM
Descriptor:NADP-specific glutamate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-OXOGLUTARIC ACID
Authors:Son, H.-F., Kim, K.-J.
Deposit date:2016-03-03
Release date:2016-03-23
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structural insights into domain movement and cofactor specificity of glutamate dehydrogenase from Corynebacterium glutamicum
BIOCHEM.BIOPHYS.RES.COMMUN., 459, 2015
5GUD
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GLUTAMATE DEHYDROGENASE FROM CORYNEBACTERIUM GLUTAMICUM (ALPHA-IMINOGLUTARATE/NADP+ COMPLEX)
Descriptor:Glutamate dehydrogenase, (2Z)-2-iminopentanedioic acid, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Tomita, T., Nishiyama, M.
Deposit date:2016-08-28
Release date:2017-06-07
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Crystal structure of the 2-iminoglutarate-bound complex of glutamate dehydrogenase from Corynebacterium glutamicum
FEBS Lett., 591, 2017
5B37
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CRYSTAL STRUCTURE OF L-TRYPTOPHAN DEHYDROGENASE FROM NOSTOC PUNCTIFORME
Descriptor:Tryptophan dehydrogenase
Authors:Wakamatsu, T., Sakuraba, H., Kitamura, M., Hakumai, Y., Ohnishi, K., Ashiuchi, M., Ohshima, T.
Deposit date:2016-02-11
Release date:2016-11-23
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural Insights into l-Tryptophan Dehydrogenase from a Photoautotrophic Cyanobacterium, Nostoc punctiforme.
Appl. Environ. Microbiol., 83, 2017
4XGI
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CRYSTAL STRUCTURE OF GLUTAMATE DEHYDROGENASE FROM BURKHOLDERIA THAILANDENSIS
Descriptor:Glutamate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 2-OXOGLUTARIC ACID, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-12-30
Release date:2015-01-14
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of Glutamate dehydrogenase from Burkholderia thailandensis
to be published
4FHN
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NUP37-NUP120 FULL-LENGTH COMPLEX FROM SCHIZOSACCHAROMYCES POMBE
Descriptor:NUCLEOPORIN NUP37, Nucleoporin nup120, Glutamate dehydrogenase
Authors:Bilokapic, S., Schwartz, T.U.
Deposit date:2012-06-06
Release date:2012-09-26
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (6.989 Å)
Cite:Molecular basis for Nup37 and ELY5/ELYS recruitment to the nuclear pore complex.
Proc.Natl.Acad.Sci.USA, 109, 2012
4FCC
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GLUTAMATE DEHYDROGENASE FROM E. COLI
Descriptor:Glutamate dehydrogenase
Authors:Bilokapic, S., Schwartz, T.U.
Deposit date:2012-05-24
Release date:2012-09-26
Last modified:2013-01-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis for Nup37 and ELY5/ELYS recruitment to the nuclear pore complex.
Proc.Natl.Acad.Sci.USA, 109, 2012
4BHT
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STRUCTURAL DETERMINANTS OF COFACTOR SPECIFICITY AND DOMAIN FLEXIBILITY IN BACTERIAL GLUTAMATE DEHYDROGENASES
Descriptor:NADP-SPECIFIC GLUTAMATE DEHYDROGENASE, GLYCEROL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Oliveira, T., Sharkey, M., Engel, P., Khan, A.
Deposit date:2013-04-06
Release date:2013-06-19
Last modified:2013-09-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of Nadp(+) -Dependent Glutamate Dehydrogenase from Escherichia Coli: Reflections on the Basis of Coenzyme Specificity in the Family of Glutamate Dehydrogenases.
FEBS J., 280, 2013
3VPX
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CRYSTAL STRUCTURE OF LEUCINE DEHYDROGENASE FROM A PSYCHROPHILIC BACTERIUM SPOROSARCINA PSYCHROPHILA.
Descriptor:Leucine dehydrogenase
Authors:Zhao, Y., Wakamatsu, T., Doi, K., Sakuraba, H., Ohshima, T.
Deposit date:2012-03-14
Release date:2013-02-06
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:A psychrophilic leucine dehydrogenase from Sporosarcina psychrophila: Purification, characterization, gene sequencing and crystal structure analysis
J.MOL.CATAL., B ENZYM., 83, 2012
3SBO
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STRUCTURE OF E.COLI GDH FROM NATIVE SOURCE
Descriptor:NADP-specific glutamate dehydrogenase, CHLORIDE ION
Authors:Gee, C.L., Zubieta, C., Echols, N., Totir, M.
Deposit date:2011-06-06
Release date:2012-03-21
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.204 Å)
Cite:Macro-to-Micro Structural Proteomics: Native Source Proteins for High-Throughput Crystallization.
Plos One, 7, 2012
3R3J
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KINETIC AND STRUCTURAL CHARACTERIZATION OF PLASMODIUM FALCIPARUM GLUTAMATE DEHYDROGENASE 2
Descriptor:Glutamate dehydrogenase
Authors:Zocher, K., Fritz-Wolf, K., Kehr, S., Rahlfs, S., Becker, K.
Deposit date:2011-03-16
Release date:2012-03-07
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Biochemical and structural characterization of Plasmodium falciparum glutamate dehydrogenase 2.
Mol.Biochem.Parasitol., 183, 2012
3K92
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CRYSTAL STRUCTURE OF A E93K MUTANT OF THE MAJOUR BACILLUS SUBTILIS GLUTAMATE DEHYDROGENASE ROCG
Descriptor:NAD-specific glutamate dehydrogenase, DI(HYDROXYETHYL)ETHER
Authors:Gunka, K., Newman, J.A., Commichau, F.M., Herzberg, C., Rodrigues, C., Hewitt, L., Lewis, R.J., Stulke, J.
Deposit date:2009-10-15
Release date:2010-06-02
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Functional dissection of a trigger enzyme: mutations of the bacillus subtilis glutamate dehydrogenase RocG that affect differentially its catalytic activity and regulatory properties
J.Mol.Biol., 400, 2010
3K8Z
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CRYSTAL STRUCTURE OF GUDB1 A DECRYPTIFIED SECONDARY GLUTAMATE DEHYDROGENASE FROM B. SUBTILIS
Descriptor:NAD-specific glutamate dehydrogenase
Authors:Gunka, K., Newman, J.A., Commichau, F.M., Herzberg, C., Rodrigues, C., Hewitt, L., Lewis, R.J., Stulke, J.
Deposit date:2009-10-15
Release date:2010-06-02
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Functional dissection of a trigger enzyme: mutations of the bacillus subtilis glutamate dehydrogenase RocG that affect differentially its catalytic activity and regulatory properties
J.Mol.Biol., 400, 2010
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