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2A74
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Human Complement Component C3c
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, Complement Component C3c, GLYCEROL, ...
Authors:Janssen, B.J.C, Huizinga, E.G, Raaijmakers, H.C.A, Roos, A, Daha, M.R, Nilsson-Ekdahl, K, Nilsson, B, Gros, P.
Deposit date:2005-07-04
Release date:2005-09-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of complement component C3 provide insights into the function and evolution of immunity.
Nature, 437, 2005
2A73
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Human Complement Component C3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Janssen, B.J.C, Huizinga, E.G, Raaijmakers, H.C.A, Roos, A, Daha, M.R, Nilsson-Ekdahl, K, Nilsson, B, Gros, P.
Deposit date:2005-07-04
Release date:2005-09-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structures of complement component C3 provide insights into the function and evolution of immunity.
Nature, 437, 2005
2I07
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BU of 2i07 by Molmil
Human Complement Component C3b
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3b, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Janssen, B.J.C, Christodoulidou, A, McCarthy, A, Lambris, J.D, Gros, P.
Deposit date:2006-08-10
Release date:2006-10-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structure of C3b reveals conformational changes that underlie complement activity.
Nature, 444, 2006
2ICE
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BU of 2ice by Molmil
CRIg bound to C3c
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C3 alpha chain, ...
Authors:Wiesmann, C.
Deposit date:2006-09-12
Release date:2006-11-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of C3b in complex with CRIg gives insights into regulation of complement activation.
Nature, 444, 2006
2ICF
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BU of 2icf by Molmil
CRIg bound to C3b
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C3 alpha chain, ...
Authors:Wiesmann, C.
Deposit date:2006-09-12
Release date:2006-11-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Structure of C3b in complex with CRIg gives insights into regulation of complement activation.
Nature, 444, 2006
2PN5
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BU of 2pn5 by Molmil
Crystal Structure of TEP1r
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, ...
Authors:Baxter, R.H.G.
Deposit date:2007-04-23
Release date:2007-07-24
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.698 Å)
Cite:Structural basis for conserved complement factor-like function in the antimalarial protein TEP1
Proc.Natl.Acad.Sci.Usa, 104, 2007
2QKI
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BU of 2qki by Molmil
Human C3c in complex with the inhibitor compstatin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BROMIDE ION, Complement C3, ...
Authors:Janssen, B.J.C, Halff, E.F, Lambris, J.D, Gros, P.
Deposit date:2007-07-11
Release date:2007-08-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition.
J.Biol.Chem., 282, 2007
3CU7
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BU of 3cu7 by Molmil
Human Complement Component 5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, ...
Authors:Fredslund, F, Andersen, G.R.
Deposit date:2008-04-16
Release date:2008-06-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.105 Å)
Cite:Structure of and influence of a tick complement inhibitor on human complement component 5
Nat.Immunol., 9, 2008
3FRP
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BU of 3frp by Molmil
Crystal Structure of Cobra Venom Factor, a Co-factor for C3- and C5 convertase CVFBb
Descriptor: CALCIUM ION, Cobra venom factor alpha chain, Cobra venom factor beta chain, ...
Authors:Krishnan, V, Narayana, S.V.L.
Deposit date:2009-01-08
Release date:2009-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:The Crystal Structure of Cobra Venom Factor, a Cofactor for C3- and C5-Convertase CVFBb.
Structure, 17, 2009
3G6J
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BU of 3g6j by Molmil
C3b in complex with a C3b specific Fab
Descriptor: CALCIUM ION, Complement C3 alpha chain, Complement C3 beta chain, ...
Authors:Wiesmann, C.
Deposit date:2009-02-06
Release date:2009-03-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural and Functional Analysis of a C3b-specific Antibody That Selectively Inhibits the Alternative Pathway of Complement
J.Biol.Chem., 284, 2009
2WII
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BU of 2wii by Molmil
Complement C3b in complex with factor H domains 1-4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COMPLEMENT C3 BETA CHAIN, ...
Authors:Wu, J, Janssen, B.J.C, Gros, P.
Deposit date:2009-05-12
Release date:2009-06-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of complement fragment C3b-factor H and implications for host protection by complement regulators.
Nat. Immunol., 10, 2009
2WIN
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BU of 2win by Molmil
C3 convertase (C3bBb) stabilized by SCIN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3 BETA CHAIN, ...
Authors:Wu, J, Janssen, B.J, Gros, P.
Deposit date:2009-05-13
Release date:2009-06-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor.
Nat. Immunol., 10, 2009
3HRZ
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Cobra Venom Factor (CVF) in complex with human factor B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cobra venom factor, ...
Authors:Janssen, B.J.C, Gomes, L, Koning, R.I, Svergun, D.I, Koster, A.J, Fritzinger, D.C, Vogel, C.-W, Gros, P.
Deposit date:2009-06-10
Release date:2009-07-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Insights into complement convertase formation based on the structure of the factor B-cobra venom factor complex
Embo J., 28, 2009
3HS0
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BU of 3hs0 by Molmil
Cobra Venom Factor (CVF) in complex with human factor B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cobra venom factor, ...
Authors:Janssen, B.J.C, Gomes, L, Koning, R.I, Svergun, D.I, Koster, A.J, Fritzinger, D.C, Vogel, C.-W, Gros, P.
Deposit date:2009-06-10
Release date:2009-07-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Insights into complement convertase formation based on the structure of the factor B-cobra venom factor complex
Embo J., 28, 2009
3KLS
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BU of 3kls by Molmil
Structure of complement C5 in complex with SSL7
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, ...
Authors:Laursen, N.S, Gordon, N, Hermans, S, Lorenz, N, Jackson, N, Wines, B, Spillner, E, Christensen, J.B, Jensen, M, Fredslund, F, Bjerre, M, Sottrup-Jensen, L, Fraser, J.D, Andersen, G.R.
Deposit date:2009-11-09
Release date:2009-11-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural basis for inhibition of complement C5 by the SSL7 protein from Staphylococcus aureus
Proc.Natl.Acad.Sci.USA, 107, 2010
3KM9
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BU of 3km9 by Molmil
Structure of complement C5 in complex with the C-terminal beta-grasp domain of SSL7
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, ...
Authors:Laursen, N.S, Gordon, N, Hermans, S, Lorenz, N, Jackson, N, Wines, B, Spillner, E, Christensen, J.B, Jensen, M, Fredslund, F, Bjerre, M, Sottrup-Jensen, L, Fraser, J.D, Andersen, G.R.
Deposit date:2009-11-10
Release date:2009-12-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Structural basis for inhibition of complement C5 by the SSL7 protein from Staphylococcus aureus
Proc.Natl.Acad.Sci.USA, 107, 2010
3L3O
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BU of 3l3o by Molmil
Staphylococcal Complement Inhibitor (SCIN) in complex with Human Complement Component C3c
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, Staphylococcal complement inhibitor
Authors:Geisbrecht, B.V, Garcia, B.G.
Deposit date:2009-12-17
Release date:2010-08-04
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.405 Å)
Cite:Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b.
J.Mol.Biol., 402, 2010
3L5N
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Staphylococcal Complement Inhibitor (SCIN) in complex with Human Complement Component C3b
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, Staphylococcal complement inhibitor, ...
Authors:Geisbrecht, B.V, Garcia, B.L.
Deposit date:2009-12-22
Release date:2010-08-04
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (7.536 Å)
Cite:Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b.
J.Mol.Biol., 402, 2010
3NMS
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BU of 3nms by Molmil
Staphylococcal Complement Inhibitor (SCIN) in complex with Human Complement C3c
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, Staphylococcal complement inhibitor
Authors:Geisbrecht, B.V, Garcia, B.L.
Deposit date:2010-06-22
Release date:2010-08-04
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b.
J.Mol.Biol., 402, 2010
3OHX
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BU of 3ohx by Molmil
Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, Staphylococcal complement inhibitor
Authors:Geisbrecht, B.V, Garcia, B.L.
Deposit date:2010-08-18
Release date:2010-09-01
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.503 Å)
Cite:Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b.
J.Mol.Biol., 402, 2010
2XWB
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BU of 2xwb by Molmil
Crystal Structure of Complement C3b in complex with Factors B and D
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3B ALPHA' CHAIN, ...
Authors:Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P.
Deposit date:2010-11-01
Release date:2011-01-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation.
Science, 330, 2010
2XWJ
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BU of 2xwj by Molmil
Crystal Structure of Complement C3b in Complex with Factor B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3 ALPHA CHAIN, COMPLEMENT C3 BETA CHAIN, ...
Authors:Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P.
Deposit date:2010-11-04
Release date:2011-01-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation.
Science, 330, 2010
3PRX
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BU of 3prx by Molmil
Structure of Complement C5 in Complex with CVF and SSL7
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cobra venom factor, ...
Authors:Laursen, N.S, Andersen, G.R, Sottrup-Jensen, L, Andersen, K.R, Spillner, E, Braren, I.
Deposit date:2010-11-30
Release date:2011-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex.
Embo J., 30, 2011
3PVM
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BU of 3pvm by Molmil
Structure of Complement C5 in Complex with CVF
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cobra venom factor, Complement C5
Authors:Laursen, N.S, Andersen, K.R, Braren, I, Sottrup-Jensen, L, Spillner, E, Andersen, G.R.
Deposit date:2010-12-07
Release date:2011-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex.
Embo J., 30, 2011
3T4A
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BU of 3t4a by Molmil
Structure of a truncated form of Staphylococcal Complement Inhibitor B bound to human C3c at 3.4 Angstrom resolution
Descriptor: Complement C3 beta chain, Complement C3c alpha' chain fragment 1, Complement C3c alpha' chain fragment 2, ...
Authors:Garcia, B.L, Geisbrecht, B.V, Summers, B.J.
Deposit date:2011-07-25
Release date:2011-11-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family.
J.Biol.Chem., 287, 2012

217705

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