2A73
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HUMAN COMPLEMENT COMPONENT C3
Descriptor:ALPHA-D-MANNOSE, BETA-D-MANNOSE, Complement C3, ...
Authors:Janssen, B.J.C., Huizinga, E.G., Raaijmakers, H.C.A., Roos, A., Daha, M.R., Nilsson-Ekdahl, K., Nilsson, B., Gros, P.
Deposit date:2005-07-04
Release date:2005-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structures of complement component C3 provide insights into the function and evolution of immunity.
Nature, 437, 2005
2A74
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HUMAN COMPLEMENT COMPONENT C3C
Descriptor:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, Complement Component C3c, GLYCEROL, ...
Authors:Janssen, B.J.C., Huizinga, E.G., Raaijmakers, H.C.A., Roos, A., Daha, M.R., Nilsson-Ekdahl, K., Nilsson, B., Gros, P.
Deposit date:2005-07-04
Release date:2005-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of complement component C3 provide insights into the function and evolution of immunity.
Nature, 437, 2005
2B39
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STRUCTURE OF MAMMALIAN C3 WITH AN INTACT THIOESTER AT 3A RESOLUTION
Descriptor:BETA-D-MANNOSE, C3, N-ACETYL-D-GLUCOSAMINE
Authors:Fredslund, F., Jenner, L., Husted, L.B., Nyborg, J., Andersen, G.R., Sottrup-Jensen, L.
Deposit date:2005-09-20
Release date:2006-06-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of bovine complement component 3 reveals the basis for thioester function.
J.Mol.Biol., 361, 2006
2I07
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HUMAN COMPLEMENT COMPONENT C3B
Descriptor:ALPHA-D-MANNOSE, Complement C3b, N-ACETYL-D-GLUCOSAMINE
Authors:Janssen, B.J.C., Christodoulidou, A., McCarthy, A., Lambris, J.D., Gros, P.
Deposit date:2006-08-10
Release date:2006-10-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structure of C3b reveals conformational changes that underlie complement activity.
Nature, 444, 2006
2ICE
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CRIG BOUND TO C3C
Descriptor:CALCIUM ION, Complement C3 alpha chain, Complement C3 beta chain, ...
Authors:Wiesmann, C.
Deposit date:2006-09-12
Release date:2006-11-07
Last modified:2012-09-05
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of C3b in complex with CRIg gives insights into regulation of complement activation.
Nature, 444, 2006
2ICF
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CRIG BOUND TO C3B
Descriptor:BETA-D-MANNOSE, CALCIUM ION, Complement C3 alpha chain, ...
Authors:Wiesmann, C.
Deposit date:2006-09-12
Release date:2006-11-07
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Structure of C3b in complex with CRIg gives insights into regulation of complement activation.
Nature, 444, 2006
2PN5
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CRYSTAL STRUCTURE OF TEP1R
Descriptor:N-ACETYL-D-GLUCOSAMINE, SODIUM ION, Thioester-containing protein I
Authors:Baxter, R.H.G.
Deposit date:2007-04-23
Release date:2007-07-24
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.698 Å)
Cite:Structural basis for conserved complement factor-like function in the antimalarial protein TEP1
Proc.Natl.Acad.Sci.Usa, 104, 2007
2QKI
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HUMAN C3C IN COMPLEX WITH THE INHIBITOR COMPSTATIN
Descriptor:BROMIDE ION, Complement C3, GLYCEROL, ...
Authors:Janssen, B.J.C., Halff, E.F., Lambris, J.D., Gros, P.
Deposit date:2007-07-11
Release date:2007-08-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition.
J.Biol.Chem., 282, 2007
3CU7
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HUMAN COMPLEMENT COMPONENT 5
Descriptor:CADMIUM ION, Complement C5, N-ACETYL-D-GLUCOSAMINE
Authors:Fredslund, F., Andersen, G.R.
Deposit date:2008-04-16
Release date:2008-06-10
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (3.105 Å)
Cite:Structure of and influence of a tick complement inhibitor on human complement component 5
Nat.Immunol., 9, 2008
3FRP
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CRYSTAL STRUCTURE OF COBRA VENOM FACTOR, A CO-FACTOR FOR C3- AND C5 CONVERTASE CVFBB
Descriptor:CALCIUM ION, Cobra venom factor alpha chain, Cobra venom factor beta chain, ...
Authors:Krishnan, V., Narayana, S.V.L.
Deposit date:2009-01-08
Release date:2009-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:The Crystal Structure of Cobra Venom Factor, a Cofactor for C3- and C5-Convertase CVFBb.
Structure, 17, 2009
3G6J
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C3B IN COMPLEX WITH A C3B SPECIFIC FAB
Descriptor:CALCIUM ION, Complement C3 alpha chain, Complement C3 beta chain, ...
Authors:Wiesmann, C.
Deposit date:2009-02-06
Release date:2009-03-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural and Functional Analysis of a C3b-specific Antibody That Selectively Inhibits the Alternative Pathway of Complement
J.Biol.Chem., 284, 2009
3KLS
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STRUCTURE OF COMPLEMENT C5 IN COMPLEX WITH SSL7
Descriptor:CADMIUM ION, Complement C5, Exotoxin 1, ...
Authors:Laursen, N.S., Gordon, N., Hermans, S., Lorenz, N., Jackson, N., Wines, B., Spillner, E., Christensen, J.B., Jensen, M., Fredslund, F., Bjerre, M., Sottrup-Jensen, L., Fraser, J.D., Andersen, G.R.
Deposit date:2009-11-09
Release date:2009-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural basis for inhibition of complement C5 by the SSL7 protein from Staphylococcus aureus
Proc.Natl.Acad.Sci.USA, 107, 2010
3KM9
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STRUCTURE OF COMPLEMENT C5 IN COMPLEX WITH THE C-TERMINAL BETA-GRASP DOMAIN OF SSL7
Descriptor:CADMIUM ION, Complement C5, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Laursen, N.S., Gordon, N., Hermans, S., Lorenz, N., Jackson, N., Wines, B., Spillner, E., Christensen, J.B., Jensen, M., Fredslund, F., Bjerre, M., Sottrup-Jensen, L., Fraser, J.D., Andersen, G.R.
Deposit date:2009-11-10
Release date:2009-12-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Structural basis for inhibition of complement C5 by the SSL7 protein from Staphylococcus aureus
Proc.Natl.Acad.Sci.USA, 107, 2010
3L3O
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STAPHYLOCOCCAL COMPLEMENT INHIBITOR (SCIN) IN COMPLEX WITH HUMAN COMPLEMENT COMPONENT C3C
Descriptor:Complement C3, N-ACETYL-D-GLUCOSAMINE, Staphylococcal complement inhibitor
Authors:Geisbrecht, B.V., Garcia, B.G.
Deposit date:2009-12-17
Release date:2010-08-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.405 Å)
Cite:Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b.
J.Mol.Biol., 402, 2010
3L5N
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STAPHYLOCOCCAL COMPLEMENT INHIBITOR (SCIN) IN COMPLEX WITH HUMAN COMPLEMENT COMPONENT C3B
Descriptor:ALPHA-D-MANNOSE, Complement C3, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Geisbrecht, B.V., Garcia, B.L.
Deposit date:2009-12-22
Release date:2010-08-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (7.536 Å)
Cite:Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b.
J.Mol.Biol., 402, 2010
3NMS
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STAPHYLOCOCCAL COMPLEMENT INHIBITOR (SCIN) IN COMPLEX WITH HUMAN COMPLEMENT C3C
Descriptor:Complement C3, N-ACETYL-D-GLUCOSAMINE, Staphylococcal complement inhibitor
Authors:Geisbrecht, B.V., Garcia, B.L.
Deposit date:2010-06-22
Release date:2010-08-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b.
J.Mol.Biol., 402, 2010
3OHX
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MOLECULAR BASIS FOR COMPLEMENT RECOGNITION AND INHIBITION DETERMINED BY CRYSTALLOGRAPHIC STUDIES OF THE STAPHYLOCOCCAL COMPLEMENT INHIBITOR (SCIN) BOUND TO C3C AND C3B
Descriptor:Complement C3, N-ACETYL-D-GLUCOSAMINE, Staphylococcal complement inhibitor
Authors:Geisbrecht, B.V., Garcia, B.L.
Deposit date:2010-08-18
Release date:2010-09-01
Last modified:2013-04-24
Method:X-RAY DIFFRACTION (3.503 Å)
Cite:Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b.
J.Mol.Biol., 402, 2010
3PRX
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STRUCTURE OF COMPLEMENT C5 IN COMPLEX WITH CVF AND SSL7
Descriptor:Cobra venom factor, Complement C5, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Laursen, N.S., Andersen, G.R., Sottrup-Jensen, L., Andersen, K.R., Spillner, E., Braren, I.
Deposit date:2010-11-30
Release date:2011-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex.
Embo J., 30, 2011
3PVM
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STRUCTURE OF COMPLEMENT C5 IN COMPLEX WITH CVF
Descriptor:Cobra venom factor, Complement C5, N-ACETYL-D-GLUCOSAMINE
Authors:Laursen, N.S., Andersen, K.R., Braren, I., Sottrup-Jensen, L., Spillner, E., Andersen, G.R.
Deposit date:2010-12-07
Release date:2011-01-19
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex.
Embo J., 30, 2011
3T4A
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STRUCTURE OF A TRUNCATED FORM OF STAPHYLOCOCCAL COMPLEMENT INHIBITOR B BOUND TO HUMAN C3C AT 3.4 ANGSTROM RESOLUTION
Descriptor:Complement C3 beta chain, Complement C3c alpha' chain fragment 1, Complement C3c alpha' chain fragment 2, ...
Authors:Garcia, B.L., Geisbrecht, B.V., Summers, B.J.
Deposit date:2011-07-25
Release date:2011-11-23
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family.
J.Biol.Chem., 287, 2012
4ACQ
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ALPHA-2 MACROGLOBULIN
Descriptor:ALPHA-2-MACROGLOBULIN, ALPHA-D-MANNOSE, N-ACETYL-D-GLUCOSAMINE
Authors:Marrero, A., Duquerroy, S., Trapani, S., Goulas, T., Guevara, T., Andersen, G.R., Navaza, J., Sottrup-Jensen, L., Gomis-Ruth, F.X.
Deposit date:2011-12-17
Release date:2012-02-22
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:The Crystal Structure of Human Alpha(2)-Macroglobulin Reveals a Unique Molecular Cage.
Angew.Chem.Int.Ed.Engl., 51, 2012
4D94
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CRYSTAL STRUCTURE OF TEP1R
Descriptor:CHLORIDE ION, N-ACETYL-D-GLUCOSAMINE, SODIUM ION, ...
Authors:Le, B.V., Williams, M., Logarajah, S., Baxter, R.H.G.
Deposit date:2012-01-11
Release date:2012-10-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular Basis for Genetic Resistance of Anopheles gambiae to Plasmodium: Structural Analysis of TEP1 Susceptible and Resistant Alleles.
Plos Pathog., 8, 2012
4FXK
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HUMAN COMPLEMENT C4
Descriptor:BETA-D-MANNOSE, Complement C4 Beta chain, Complement C4 gamma chain, ...
Authors:Kidmose, R.T., Laursen, N.S., Andersen, G.R.
Deposit date:2012-07-03
Release date:2012-08-22
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural basis for activation of the complement system by component C4 cleavage.
Proc.Natl.Acad.Sci.USA, 109, 2012
4LNV
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CRYSTAL STRUCTURE OF TEP1S
Descriptor:N-ACETYL-D-GLUCOSAMINE, Thioester-containing protein I
Authors:Le, B.V., Williams, M., Logarajah, S., Baxter, R.H.G.
Deposit date:2013-07-12
Release date:2013-07-24
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Molecular basis for genetic resistance of Anopheles gambiae to Plasmodium: structural analysis of TEP1 susceptible and resistant alleles.
Plos Pathog., 8, 2012
4RTD
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ESCHERICHIA COLI ALPHA-2-MACROGLOBULIN ACTIVATED BY PORCINE ELASTASE
Descriptor:Uncharacterized lipoprotein YfhM
Authors:Fyfe, C.D., Grinter, R., Roszak, A.W., Josts, I., Cogdell, R.J., Walker, D.
Deposit date:2014-11-14
Release date:2015-07-15
Last modified:2015-07-29
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Structure of protease-cleaved Escherichia coli alpha-2-macroglobulin reveals a putative mechanism of conformational activation for protease entrapment.
Acta Crystallogr.,Sect.D, 71, 2015
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