PDB: 53 resultsInfo pagesStatus searchChemie searchBIRD

---

8Y6B	Structure of human LGI1-ADAM22 complex in space group P212121 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 22, ... Authors: Liu, H, Xu, F. Deposit date: 2024-02-02 Release date: 2024-02-14 Method: X-RAY DIFFRACTION (3.49 Å) Cite: Structure of human LGI1-ADAM22 complex in space group P212121 To Be Published
8S9E	Solution structure of jarastatin (rJast), a disintegrin from Bothrops jararaca Descriptor: Disintegrin jarastatin Authors: Vasconcelos, A.A, Estrada, J.E.C, Zingali, R.B, Almeida, F.C.L. Deposit date: 2023-03-28 Release date: 2023-11-29 Method: SOLUTION NMR Cite: Toward the mechanism of jarastatin (rJast) inhibition of the integrin alpha V beta 3 Int.J.Biol.Macromol., 255, 2024
8GH4	Complex of Adam 10 disentegrin cysteine rich domains with human monoclonal antibody Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody heavy chain, Antibody light chain, ... Authors: Nikolov, D.B, Saha, N, Xu, K, Goldgur, Y. Deposit date: 2023-03-09 Release date: 2023-08-30 Method: X-RAY DIFFRACTION (3.8 Å) Cite: Fully human monoclonal antibody targeting activated ADAM10 on colorectal cancer cells. Biomed Pharmacother, 161, 2023
8HQ2	Crystal structure of human ADAM22 in complex with human LGI1 mutant Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 22, ... Authors: Liu, H, Lin, Z, Xu, F. Deposit date: 2022-12-13 Release date: 2023-12-13 Method: X-RAY DIFFRACTION (2.93 Å) Cite: Crystal structure of human ADAM22 in complex with human LGI1 mutant To Be Published
8HQ1	Crystal Structure Of Human Lgi1-Adam22 Complex In Space Group C2 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 22, ... Authors: Liu, H.L, Lin, Z.H, Xu, F. Deposit date: 2022-12-13 Release date: 2023-12-13 Method: X-RAY DIFFRACTION (4.17 Å) Cite: Structure Of Human Lgi1-Adam22 Complex In Space Group C2 To Be Published
8HPY	Crystal structure of human LGI1-ADAM22 complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 22, ... Authors: Liu, H, Xu, F. Deposit date: 2022-12-13 Release date: 2023-12-13 Method: X-RAY DIFFRACTION (5.87 Å) Cite: Crystal structure of human LGI1-ADAM22 complex To Be Published
8ESV	Structure of human ADAM10-Tspan15 complex bound to 11G2 vFab Descriptor: 11G2 Fab Heavy Chain, 11G2 Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Lipper, C.H, Blacklow, S.C. Deposit date: 2022-10-14 Release date: 2023-06-14 Last modified: 2023-08-30 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis for membrane-proximal proteolysis of substrates by ADAM10. Cell, 186, 2023
7X4Z	Crystal structure of Rhodostomin ARGDWP mutant Descriptor: Disintegrin rhodostomin, SULFATE ION Authors: Chang, Y.T, Chuang, W.J. Deposit date: 2022-03-03 Release date: 2023-03-08 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.48 Å) Cite: Crystal structure of Rhodostomin ARGDWP mutant To be published
7X4V	Crystal structure of Rhodostomin ARGDDP mutant Descriptor: Disintegrin rhodostomin Authors: Chang, Y.T, Chuang, W.J. Deposit date: 2022-03-03 Release date: 2023-03-08 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.38 Å) Cite: Crystal structure of Rhodostomin ARGDDP mutant To be published
7X4S	Crystal structure of Rhodostomin ARGDMP mutant Descriptor: Disintegrin rhodostomin Authors: Chang, Y.T, Chuang, W.J. Deposit date: 2022-03-03 Release date: 2023-03-08 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of Rhodostomin ARGDMP mutant To be published
6LSQ	Crystal structure of Echistatin, an RGD-containing short disintegrin Descriptor: Disintegrin, SULFATE ION Authors: Chang, Y.T, Chen, Y.C, Chuang, W.J. Deposit date: 2020-01-19 Release date: 2020-11-25 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural Insight into Integrin Recognition and Anticancer Activity of Echistatin. Toxins, 12, 2020
6BDZ	ADAM10 Extracellular Domain Bound by the 11G2 Fab Descriptor: 11G2 Fab Heavy Chain, 11G2 Fab Light Chain, CALCIUM ION, ... Authors: Seegar, T.C.M. Deposit date: 2017-10-24 Release date: 2017-12-27 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structural Basis for Regulated Proteolysis by the alpha-Secretase ADAM10. Cell, 171, 2017
6BE6	ADAM10 Extracellular Domain Descriptor: CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 10, SULFATE ION, ... Authors: Seegar, T.C.M. Deposit date: 2017-10-24 Release date: 2017-12-27 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural Basis for Regulated Proteolysis by the alpha-Secretase ADAM10. Cell, 171, 2017
5Y31	Crystal structure of human LGI1-ADAM22 complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 22, ... Authors: Yamagata, A, Fukai, S. Deposit date: 2017-07-27 Release date: 2018-05-02 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (7.125 Å) Cite: Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22. Nat Commun, 9, 2018
5Y2Z	Crystal structure of human LGI1 EPTP-ADAM22 complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Yamagata, A, Fukai, S. Deposit date: 2017-07-27 Release date: 2018-05-02 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.67 Å) Cite: Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22. Nat Commun, 9, 2018
5L0Q	Crystal structure of the complex between ADAM10 D+C domain and a conformation specific mAb 8C7. Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Disintegrin and metalloproteinase domain-containing protein 10, MAGNESIUM ION, ... Authors: Xu, K, Saha, N, Nikolov, D.B. Deposit date: 2016-07-28 Release date: 2016-11-09 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.759 Å) Cite: An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth. J.Exp.Med., 213, 2016
4RQG	Crystal structure of Rhodostomin Descriptor: Disintegrin rhodostomin Authors: Shiu, J.H, Huang, C.H, Chang, Y.T, Jeng, W.Y, Chuang, W.J. Deposit date: 2014-11-03 Release date: 2015-11-04 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.66 Å) Cite: Effects of the regions adjacent to the RGD motif in disintegrins on their inhibitory activities and structures To be Published
4R5U	Crystal structure of Rhodostomin R46E mutant Descriptor: Disintegrin rhodostomin Authors: Huang, C.H, Shiu, J.H, Chang, Y.T, Jeng, W.Y, Chuang, W.J. Deposit date: 2014-08-22 Release date: 2015-08-26 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (1.81 Å) Cite: Effects of the regions adjacent to the RGD motif in disintegrins on their inhibitory activities and structures To be Published
4R5R	Crystal structure of Rhodostomin KKKRT mutant Descriptor: Disintegrin rhodostomin Authors: Huang, C.H, Shiu, J.H, Chang, Y.T, Jeng, W.Y, Chuang, W.J. Deposit date: 2014-08-21 Release date: 2015-08-26 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (0.96 Å) Cite: Effects of the regions adjacent to the RGD motif in disintegrins on their inhibitory activities and structures To be Published
2MP5	Structure of Bitistatin B Descriptor: Disintegrin bitistatin Authors: Carbajo, R.J, Calvete, J, Sanz, L, Perez, A. Deposit date: 2014-05-11 Release date: 2014-11-12 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: NMR structure of bitistatin - a missing piece in the evolutionary pathway of snake venom disintegrins. Febs J., 282, 2015
2MOP	Structure of Bitistatin A Descriptor: Disintegrin bitistatin Authors: Carbajo, R.J, Calvete, J, Sanz, L, Perez, A. Deposit date: 2014-04-29 Release date: 2014-11-12 Last modified: 2015-02-25 Method: SOLUTION NMR Cite: NMR structure of bitistatin - a missing piece in the evolutionary pathway of snake venom disintegrins. Febs J., 282, 2015
4M4C	Crystal structure of Rhodostomin ARGDP mutant Descriptor: SULFATE ION, Zinc metalloproteinase/disintegrin Authors: Chang, Y.T, Jeng, W.Y, Shiu, J.H, Chen, C.Y, Chuang, W.J. Deposit date: 2013-08-07 Release date: 2014-08-13 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Effect of C-terminal proline residue adjacent to the RGD motif in rhodostomin on its activity and structure To be Published
2M7H	The C-terminal Region of Disintegrin Modulate its 3D Conformation and Cooperate with RGD Loop in Regulating Integrin alpha-IIb beta-3 Recognition Descriptor: Zinc metalloproteinase/disintegrin Authors: Chuang, W, Chang, Y. Deposit date: 2013-04-22 Release date: 2013-05-22 Method: SOLUTION NMR Cite: The C-terminal Region of Disintegrin Modulate its 3D Conformation and Cooperate with RGD Loop in Regulating Recognitions of Integrins To be Published
2M7F	The C-terminal Region of Disintegrin Modulate its 3D Conformation and Cooperate with RGD Loop in Regulating Integrins Recognitions Descriptor: Zinc metalloproteinase/disintegrin Authors: Chuang, W, Chang, Y. Deposit date: 2013-04-22 Release date: 2013-05-22 Method: SOLUTION NMR Cite: The C-terminal Region of Disintegrin Modulate its 3D Conformation and Cooperate with RGD Loop in Regulating Recognitions of Integrins To be Published
2M75	The C-terminal Region of Disintegrin Modulate its 3D Conformation and Cooperate with RGD Loop in Regulating Recognitions of Integrins Descriptor: Zinc metalloproteinase/disintegrin Authors: Chuang, W, Chang, Y, Shiu, J. Deposit date: 2013-04-18 Release date: 2013-05-22 Method: SOLUTION NMR Cite: The C-terminal Region of Disintegrin Modulate its 3D Conformation and Cooperate with RGD Loop in Regulating Recognitions of Integrins To be Published

 

123>