1J2L
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CRYSTAL STRUCTURE OF THE DISINTEGRIN, TRIMESTATIN
Descriptor:Disintegrin triflavin, SULFATE ION
Authors:Fujii, Y., Okuda, D., Fujimoto, Z., Morita, T., Mizuno, H.
Deposit date:2003-01-06
Release date:2003-10-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of Trimestatin, a Disintegrin Containing a Cell Adhesion Recognition Motif RGD
J.Mol.Biol., 332, 2003
1L3X
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SOLUTION STRUCTURE OF NOVEL DISINTEGRIN SALMOSIN
Descriptor:platelet aggregation inhibitor disintegrin
Authors:Shin, J., Lee, W.
Deposit date:2002-03-01
Release date:2003-12-23
Last modified:2012-11-21
Method:SOLUTION NMR
Cite:Solution structure of a novel disintegrin, salmosin, from Agkistrondon halys venom
Biochemistry, 42, 2003
1RMR
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CRYSTAL STRUCTURE OF SCHISTATIN, A DISINTEGRIN HOMODIMER FROM SAW-SCALED VIPER (ECHIS CARINATUS) AT 2.5 A RESOLUTION
Descriptor:Disintegrin schistatin
Authors:Bilgrami, S., Tomar, S., Yadav, S., Kaur, P., Kumar, J., Jabeen, T., Sharma, S., Singh, T.P.
Deposit date:2003-11-28
Release date:2004-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of schistatin, a disintegrin homodimer from saw-scaled viper (Echis carinatus) at 2.5 A resolution
J.Mol.Biol., 341, 2004
1TEJ
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CRYSTAL STRUCTURE OF A DISINTEGRIN HETERODIMER AT 1.9 A RESOLUTION.
Descriptor:disintegrin chain A, disintegrin chain B
Authors:Bilgrami, S., Kaur, P., Yadav, S., Perbandt, M., Betzel, C., Singh, T.P.
Deposit date:2004-05-25
Release date:2004-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of the Disintegrin Heterodimer from Saw-Scaled Viper (Echis carinatus) at 1.9 A Resolution
Biochemistry, 44, 2005
1Z1X
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CRYSTAL STRUCTURE OF A NOVEL DISINTEGRIN FROM SAW-SCALED VIPER AT 3.2 A RESOLUTION
Descriptor:disintegrin
Authors:Hassan, M.I., Ethayathulla, A.S., Bilgrami, S., Singh, B., Yadav, S., Singh, T.P.
Deposit date:2005-03-07
Release date:2005-04-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal Structure of a novel disintegrin from Saw-scaled viper at 3.2A resolution
To be published
2AO7
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ADAM10 DISINTEGRIN AND CYSTEINE- RICH DOMAIN
Descriptor:ADAM 10, SULFATE ION
Authors:Janes, P.W., Saha, N., Barton, W.A., Kolev, M.V., Wimmer-Kleikamp, S.H., Nievergall, E., Blobel, C.P., Himanen, J.-P., Lackmann, M., Nikolov, D.B.
Deposit date:2005-08-12
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans.
Cell(Cambridge,Mass.), 123, 2005
2MOP
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STRUCTURE OF BITISTATIN A
Descriptor:Disintegrin bitistatin
Authors:Carbajo, R.J., Calvete, J., Sanz, L., Perez, A.
Deposit date:2014-04-29
Release date:2014-11-12
Last modified:2015-02-25
Method:SOLUTION NMR
Cite:NMR structure of bitistatin - a missing piece in the evolutionary pathway of snake venom disintegrins.
Febs J., 282, 2015
2MP5
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STRUCTURE OF BITISTATIN B
Descriptor:Disintegrin bitistatin
Authors:Carbajo, R.J., Calvete, J., Sanz, L., Perez, A.
Deposit date:2014-05-11
Release date:2014-11-12
Last modified:2015-02-25
Method:SOLUTION NMR
Cite:NMR structure of bitistatin - a missing piece in the evolutionary pathway of snake venom disintegrins.
Febs J., 282, 2015
5L0Q
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN ADAM10 D+C DOMAIN AND A CONFORMATION SPECIFIC MAB 8C7.
Descriptor:Disintegrin and metalloproteinase domain-containing protein 10, mAb 8C7 light chain, mAb 8C7 heavy chain, ...
Authors:Xu, K., Saha, N., Nikolov, D.B.
Deposit date:2016-07-28
Release date:2016-11-09
Method:X-RAY DIFFRACTION (2.759 Å)
Cite:An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth.
J.Exp.Med., 213, 2016
2DW0
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CRYSTAL STRUCTURE OF VAP2 FROM CROTALUS ATROX VENOM (FORM 2-1 CRYSTAL)
Descriptor:Catrocollastatin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Takeda, S., Igarashi, T., Araki, S.
Deposit date:2006-08-02
Release date:2007-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structures of catrocollastatin/VAP2B reveal a dynamic, modular architecture of ADAM/adamalysin/reprolysin family proteins
Febs Lett., 581, 2007
2DW1
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CRYSTAL STRUCTURE OF VAP2 FROM CROTALUS ATROX VENOM (FORM 2-2 CRYSTAL)
Descriptor:Catrocollastatin, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Takeda, S., Igarashi, T., Araki, S.
Deposit date:2006-08-02
Release date:2007-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of catrocollastatin/VAP2B reveal a dynamic, modular architecture of ADAM/adamalysin/reprolysin family proteins
Febs Lett., 581, 2007
2DW2
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CRYSTAL STRUCTURE OF VAP2 FROM CROTALUS ATROX VENOM (FORM 2-5 CRYSTAL)
Descriptor:Catrocollastatin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Takeda, S., Igarashi, T., Araki, S.
Deposit date:2006-08-02
Release date:2007-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of catrocollastatin/VAP2B reveal a dynamic, modular architecture of ADAM/adamalysin/reprolysin family proteins
Febs Lett., 581, 2007
2E3X
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CRYSTAL STRUCTURE OF RUSSELL'S VIPER VENOM METALLOPROTEINASE
Descriptor:Coagulation factor X-activating enzyme heavy chain, Coagulation factor X-activating enzyme light chain 2, Coagulation factor X-activating enzyme light chain 1, ...
Authors:Igarashi, T., Takeda, S.
Deposit date:2006-11-30
Release date:2007-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Crystal structure of RVV-X: An example of evolutionary gain of specificity by ADAM proteinases
FEBS LETT., 2007
2ERO
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CRYSTAL STRUCTURE OF VASCULAR APOPTOSIS-INDUCING PROTEIN-1(ORTHORHOMBIC CRYSTAL FORM)
Descriptor:vascular apoptosis-inducing protein 1, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
Authors:Takeda, S., Igarashi, T., Araki, S.
Deposit date:2005-10-25
Release date:2006-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of VAP1 reveal ADAMs' MDC domain architecture and its unique C-shaped scaffold
Embo J., 25, 2006
2ERP
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CRYSTAL STRUCTURE OF VASCULAR APOPTOSIS-INDUCING PROTEIN-1(INHIBITOR-BOUND FORM)
Descriptor:vascular apoptosis-inducing protein 1, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
Authors:Takeda, S., Igarashi, T., Araki, S.
Deposit date:2005-10-25
Release date:2006-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal structures of VAP1 reveal ADAMs' MDC domain architecture and its unique C-shaped scaffold
Embo J., 25, 2006
2ERQ
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CRYSTAL STRUCTURE OF VASCULAR APOPTOSIS-INDUCING PROTEIN-1(TETRAGONAL CRYSTAL FORM)
Descriptor:vascular apoptosis-inducing protein 1, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
Authors:Takeda, S., Igarashi, T., Araki, S.
Deposit date:2005-10-25
Release date:2006-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of VAP1 reveal ADAMs' MDC domain architecture and its unique C-shaped scaffold
Embo J., 25, 2006
3DSL
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THE THREE-DIMENSIONAL STRUCTURE OF BOTHROPASIN, THE MAIN HEMORRHAGIC FACTOR FROM BOTHROPS JARARACA VENOM.
Descriptor:Zinc metalloproteinase-disintegrin bothropasin, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ...
Authors:Muniz, J.R.C., Ambrosio, A., Selistre-de-Araujo, H.S., Oliva, G., Garratt, R.C., Souza, D.H.F.
Deposit date:2008-07-13
Release date:2008-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The three-dimensional structure of bothropasin, the main hemorrhagic factor from Bothrops jararaca venom: Insights for a new classification of snake venom metalloprotease subgroups.
Toxicon, 52, 2008
3G5C
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STRUCTURAL AND BIOCHEMICAL STUDIES ON THE ECTODOMAIN OF HUMAN ADAM22
Descriptor:ADAM 22, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION
Authors:Liu, H., Shim, A., Chen, X., He, X.
Deposit date:2009-02-04
Release date:2009-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structural and biochemical studies on the ectodomain of human ADAM22
J.Biol.Chem., 2009
3K7L
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STRUCTURES OF TWO ELAPID SNAKE VENOM METALLOPROTEASES WITH DISTINCT ACTIVITIES HIGHLIGHT THE DISULFIDE PATTERNS IN THE D DOMAIN OF ADAMALYSIN FAMILY PROTEINS
Descriptor:Atragin, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
Authors:Guan, H.H., Wu, W.G., Chen, C.J.
Deposit date:2009-10-13
Release date:2010-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of two elapid snake venom metalloproteases with distinct activities highlight the disulfide patterns in the D domain of ADAMalysin family proteins
J.Struct.Biol., 169, 2010
5Y2Z
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CRYSTAL STRUCTURE OF HUMAN LGI1 EPTP-ADAM22 COMPLEX
Descriptor:Disintegrin and metalloproteinase domain-containing protein 22, Leucine-rich glioma-inactivated protein 1, CALCIUM ION, ...
Authors:Yamagata, A., Fukai, S.
Deposit date:2017-07-27
Release date:2018-05-02
Last modified:2018-10-31
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22.
Nat Commun, 9, 2018
5Y31
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CRYSTAL STRUCTURE OF HUMAN LGI1-ADAM22 COMPLEX
Descriptor:Disintegrin and metalloproteinase domain-containing protein 22, Leucine-rich glioma-inactivated protein 1, CALCIUM ION, ...
Authors:Yamagata, A., Fukai, S.
Deposit date:2017-07-27
Release date:2018-05-02
Last modified:2018-11-07
Method:X-RAY DIFFRACTION (7.125 Å)
Cite:Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22.
Nat Commun, 9, 2018
6BDZ
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ADAM10 EXTRACELLULAR DOMAIN BOUND BY THE 11G2 FAB
Descriptor:11G2 Fab Light Chain, 11G2 Fab Heavy Chain, Disintegrin and metalloproteinase domain-containing protein 10, ...
Authors:Seegar, T.C.M.
Deposit date:2017-10-24
Release date:2017-12-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis for Regulated Proteolysis by the alpha-Secretase ADAM10.
Cell, 171, 2017
6BE6
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ADAM10 EXTRACELLULAR DOMAIN
Descriptor:Disintegrin and metalloproteinase domain-containing protein 10, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Seegar, T.C.M.
Deposit date:2017-10-24
Release date:2017-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for Regulated Proteolysis by the alpha-Secretase ADAM10.
Cell, 171, 2017
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