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2CPL
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SIMILARITIES AND DIFFERENCES BETWEEN HUMAN CYCLOPHILIN A AND OTHER BETA-BARREL STRUCTURES. STRUCTURAL REFINEMENT AT 1.63 ANGSTROMS RESOLUTION
Descriptor: CYCLOPHILIN A
Authors:Ke, H.
Deposit date:1992-06-30
Release date:1993-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Similarities and differences between human cyclophilin A and other beta-barrel structures. Structural refinement at 1.63 A resolution.
J.Mol.Biol., 228, 1992
1CLH
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THREE-DIMENSIONAL SOLUTION STRUCTURE OF ESCHERICHIA COLI PERIPLASMIC CYCLOPHILIN
Descriptor: CYCLOPHILIN
Authors:Clubb, R.T, Wagner, G.
Deposit date:1993-12-20
Release date:1994-05-31
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of Escherichia coli periplasmic cyclophilin
Biochemistry, 33, 1994
3CYS
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DETERMINATION OF THE NMR SOLUTION STRUCTURE OF THE CYCLOPHILIN A-CYCLOSPORIN A COMPLEX
Descriptor: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Spitzfaden, C, Braun, W, Wider, G, Widmer, H, Wuthrich, K.
Deposit date:1994-02-28
Release date:1994-08-31
Last modified:2017-11-01
Method:SOLUTION NMR
Cite:Determination of the NMR Solution Structure of the Cyclophilin A-Cyclosporin a Complex.
J.Biomol.NMR, 4, 1994
2RMA
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Crystal structures of cyclophilin A complexed with cyclosporin A and N-methyl-4-[(E)-2-butenyl]-4,4-dimethylthreonine cyclosporin A
Descriptor: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE
Authors:Ke, H, Mayrose, D.
Deposit date:1994-01-07
Release date:1995-02-07
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of Cyclophilin a Complexed with Cyclosporin a and N-Methyl-4-[(E)-2-Butenyl]-4,4-Dimethylthreonine Cyclosporin A.
Structure, 2, 1994
2RMB
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Crystal structures of cyclophilin A complexed with cyclosporin A and N-methyl-4-[(E)-2-butenyl]-4,4-dimethylthreonine cyclosporin A
Descriptor: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE
Authors:Ke, H, Mayrose, D.
Deposit date:1994-01-07
Release date:1995-02-07
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of Cyclophilin a Complexed with Cyclosporin a and N-Methyl-4-[(E)-2-Butenyl]-4,4-Dimethylthreonine Cyclosporin A.
Structure, 2, 1994
2RMC
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Crystal structure of murine cyclophilin C complexed with immunosuppressive drug cyclosporin A
Descriptor: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE C
Authors:Ke, H, Zhao, Y, Luo, F, Weissman, I, Friedman, J.
Deposit date:1994-01-07
Release date:1995-02-14
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Crystal Structure of Murine Cyclophilin C Complexed with Immunosuppressive Drug Cyclosporin A
Proc.Natl.Acad.Sci.USA, 90, 1993
1CWC
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IMPROVED BINDING AFFINITY FOR CYCLOPHILIN A BY A CYCLOSPORIN DERIVATIVE SINGLY MODIFIED AT ITS EFFECTOR DOMAIN
Descriptor: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Mikol, V.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Improved Binding Affinity for Cyclophilin a by a Cyclosporin Derivative Singly Modified at its Effector Domain.
J.Med.Chem., 37, 1994
1CWB
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THE X-RAY STRUCTURE OF (MEBM2T)1-CYCLOSPORIN COMPLEXED WITH CYCLOPHILIN A PROVIDES AN EXPLANATION FOR ITS ANOMALOUSLY HIGH IMMUNOSUPPRESSIVE ACTIVITY
Descriptor: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Mikol, V, Kallen, J, Walkinshaw, M.D.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The X-Ray Structure of (Mebm2T)1-Cyclosporin Complexed with Cyclophilin a Provides an Explanation for its Anomalously High Immunosuppressive Activity.
Protein Eng., 7, 1994
1CYN
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CYCLOPHILIN B COMPLEXED WITH [D-(CHOLINYLESTER)SER8]-CYCLOSPORIN
Descriptor: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE B
Authors:Mikol, V, Kallen, J, Walkinshaw, M.D.
Deposit date:1995-05-22
Release date:1996-01-29
Last modified:2018-09-12
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:X-Ray Structure of a Cyclophilin B/Cyclosporin Complex: Comparison with Cyclophilin a and Delineation of its Calcineurin-Binding Domain.
Proc.Natl.Acad.Sci.USA, 91, 1994
1CWA
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X-RAY STRUCTURE OF A MONOMERIC CYCLOPHILIN A-CYCLOSPORIN A CRYSTAL COMPLEX AT 2.1 ANGSTROMS RESOLUTION
Descriptor: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Mikol, V, Kallen, J, Walkinshaw, M.D.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-Ray Structure of a Monomeric Cyclophilin A-Cyclosporin a Crystal Complex at 2.1 A Resolution.
J.Mol.Biol., 234, 1993
1MIK
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THE ROLE OF WATER MOLECULES IN THE STRUCTURE-BASED DESIGN OF (5-HYDROXYNORVALINE)-2-CYCLOSPORIN: SYNTHESIS, BIOLOGICAL ACTIVITY, AND CRYSTALLOGRAPHIC ANALYSIS WITH CYCLOPHILIN A
Descriptor: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Mikol, V.
Deposit date:1995-09-20
Release date:1996-03-08
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:The Role of Water Molecules in the Structure-Based Design of (5-Hydroxynorvaline)-2-Cyclosporin: Synthesis, Biological Activity, and Crystallographic Analysis with Cyclophilin A.
J.Med.Chem., 38, 1995
5CYH
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CYCLOPHILIN A COMPLEXED WITH DIPEPTIDE GLY-PRO
Descriptor: CYCLOPHILIN A, GLYCINE, PROLINE
Authors:Zhao, Y, Ke, H.
Deposit date:1996-02-27
Release date:1996-07-11
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanistic implication of crystal structures of the cyclophilin-dipeptide complexes.
Biochemistry, 35, 1996
3CYH
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CYCLOPHILIN A COMPLEXED WITH DIPEPTIDE SER-PRO
Descriptor: CYCLOPHILIN A, PROLINE, SERINE
Authors:Zhao, Y, Ke, H.
Deposit date:1996-02-27
Release date:1996-07-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanistic implication of crystal structures of the cyclophilin-dipeptide complexes.
Biochemistry, 35, 1996
4CYH
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CYCLOPHILIN A COMPLEXED WITH DIPEPTIDE HIS-PRO
Descriptor: CYCLOPHILIN A, HISTIDINE, PROLINE
Authors:Zhao, Y, Ke, H.
Deposit date:1996-02-27
Release date:1996-07-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanistic implication of crystal structures of the cyclophilin-dipeptide complexes.
Biochemistry, 35, 1996
2CYH
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CYCLOPHILIN A COMPLEXED WITH DIPEPTIDE ALA-PRO
Descriptor: ALANINE, CYCLOPHILIN A, PROLINE
Authors:Zhao, Y, Ke, H.
Deposit date:1996-02-27
Release date:1996-07-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Mechanistic implication of crystal structures of the cyclophilin-dipeptide complexes.
Biochemistry, 35, 1996
1RMH
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RECOMBINANT CYCLOPHILIN A FROM HUMAN T CELL
Descriptor: AAPF PEPTIDE SUBSTRATE, CYCLOPHILIN A
Authors:Zhao, Y, Ke, H.
Deposit date:1995-07-31
Release date:1996-10-14
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure implies that cyclophilin predominantly catalyzes the trans to cis isomerization.
Biochemistry, 35, 1996
1LOP
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CYCLOPHILIN A COMPLEXED WITH SUCCINYL-ALA-PRO-ALA-P-NITROANILIDE
Descriptor: CYCLOPHILIN A, SUCCINYL-ALA-PRO-ALA-P-NITROANILIDE
Authors:Konno, M.
Deposit date:1996-06-17
Release date:1996-12-23
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The substrate-binding site in Escherichia coli cyclophilin A preferably recognizes a cis-proline isomer or a highly distorted form of the trans isomer.
J.Mol.Biol., 256, 1996
1FGL
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Cyclophilin A complexed with a fragment of HIV-1 GAG protein
Descriptor: CYCLOPHILIN A, HIV-1 GAG PROTEIN
Authors:Zhao, Y, Chen, Y, Schutkowski, M, Fischer, G, Ke, H.
Deposit date:1996-11-18
Release date:1997-04-01
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Cyclophilin A complexed with a fragment of HIV-1 gag protein: insights into HIV-1 infectious activity.
Structure, 5, 1997
1AK4
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HUMAN CYCLOPHILIN A BOUND TO THE AMINO-TERMINAL DOMAIN OF HIV-1 CAPSID
Descriptor: CYCLOPHILIN A, HIV-1 CAPSID
Authors:Hill, C.P, Gamble, T.R, Vajdos, F.F, Worthylake, D.K, Sundquist, W.I.
Deposit date:1997-05-28
Release date:1997-10-15
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Crystal structure of human cyclophilin A bound to the amino-terminal domain of HIV-1 capsid.
Cell(Cambridge,Mass.), 87, 1996
1OCA
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HUMAN CYCLOPHILIN A, UNLIGATED, NMR, 20 STRUCTURES
Descriptor: CYCLOPHILIN A
Authors:Ottiger, M, Zerbe, O, Guntert, P, Wuthrich, K.
Deposit date:1997-07-07
Release date:1997-11-19
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:The NMR solution conformation of unligated human cyclophilin A.
J.Mol.Biol., 272, 1997
2NUL
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PEPTIDYLPROLYL ISOMERASE FROM E. COLI
Descriptor: PEPTIDYLPROLYL ISOMERASE
Authors:Edwards, K.J, Ollis, D.L.
Deposit date:1996-11-14
Release date:1997-11-19
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of cytoplasmic Escherichia coli peptidyl-prolyl isomerase: evidence for decreased mobility of loops upon complexation.
J.Mol.Biol., 271, 1997
1AWU
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CYPA COMPLEXED WITH HVGPIA (PSEUDO-SYMMETRIC MONOMER)
Descriptor: CYCLOPHILIN A, PEPTIDE FROM THE HIV-1 CAPSID PROTEIN
Authors:Vajdos, F.F.
Deposit date:1997-10-05
Release date:1998-03-18
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Crystal structure of cyclophilin A complexed with a binding site peptide from the HIV-1 capsid protein.
Protein Sci., 6, 1997
1AWV
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CYPA COMPLEXED WITH HVGPIA
Descriptor: CYCLOPHILIN A, PEPTIDE FROM THE HIV-1 CAPSID PROTEIN
Authors:Vajdos, F.F.
Deposit date:1997-10-05
Release date:1998-03-18
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Crystal structure of cyclophilin A complexed with a binding site peptide from the HIV-1 capsid protein.
Protein Sci., 6, 1997
1AWT
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SECYPA COMPLEXED WITH HAGPIA
Descriptor: CYCLOPHILIN A, PEPTIDE FROM THE HIV-1 CAPSID PROTEIN
Authors:Vajdos, F.F.
Deposit date:1997-10-05
Release date:1998-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure of cyclophilin A complexed with a binding site peptide from the HIV-1 capsid protein.
Protein Sci., 6, 1997
1AWR
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CYPA COMPLEXED WITH HAGPIA
Descriptor: CYCLOPHILIN A, PEPTIDE FROM THE HIV-1 CAPSID PROTEIN
Authors:Vajdos, F.F.
Deposit date:1997-10-04
Release date:1998-03-18
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Crystal structure of cyclophilin A complexed with a binding site peptide from the HIV-1 capsid protein.
Protein Sci., 6, 1997

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