1CQT
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CRYSTAL STRUCTURE OF A TERNARY COMPLEX CONTAINING AN OCA-B PEPTIDE, THE OCT-1 POU DOMAIN, AND AN OCTAMER ELEMENT
Descriptor:DNA (5'-D(*TP*GP*TP*AP*TP*GP*CP*AP*AP*AP*TP*AP*AP*GP*G)-3'), DNA (5'-D(*AP*CP*CP*TP*TP*AP*TP*TP*TP*GP*CP*AP*TP*AP*C)-3'), POU DOMAIN, ...
Authors:Chasman, D.I., Cepek, K., Sharp, P.A., Pabo, C.O.
Deposit date:1999-08-11
Release date:1999-11-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of an OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface.
Genes Dev., 13, 1999
1E3O
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CRYSTAL STRUCTURE OF OCT-1 POU DIMER BOUND TO MORE
Descriptor:5'-D(*AP*TP*GP*CP*AP*TP*GP*AP*GP*GP*A)-3', 5'-D(*TP*CP*CP*TP*CP*AP*TP*GP*CP*AP*T)-3', OCTAMER-BINDING TRANSCRIPTION FACTOR 1
Authors:Remenyi, A., Tomilin, A., Pohl, E., Schoeler, H., Wilmanns, M.
Deposit date:2000-06-20
Release date:2001-11-10
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Differential Dimer Activities of the Transcription Factor Oct-1 by DNA-Induced Interface Swapping
Mol.Cell, 8, 2001
1GT0
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CRYSTAL STRUCTURE OF A POU/HMG/DNA TERNARY COMPLEX
Descriptor:5'-D(*TP*TP*CP*TP*TP*TP*GP*TP*TP*TP* GP*GP*AP* TP*GP*CP*TP*AP*AP*TP*GP*GP*GP*A)-3', 5'-D(*AP*TP*CP*CP*CP*AP*TP*TP*AP*GP* CP*AP*TP*CP*CP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3', OCTAMER-BINDING TRANSCRIPTION FACTOR 1, ...
Authors:Remenyi, A., Wilmanns, M.
Deposit date:2002-01-09
Release date:2003-01-30
Last modified:2012-11-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of a POU/Hmg/DNA Ternary Complex Suggests Differential Assembly of Oct4 and Sox2 on Two Enhancers
Genes Dev., 17, 2003
1HF0
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CRYSTAL STRUCTURE OF THE DNA-BINDING DOMAIN OF OCT-1 BOUND TO DNA AS A DIMER
Descriptor:OCTAMER-BINDING TRANSCRIPTION FACTOR 1, DNA 5'-D(*CP*AP*CP*AP*TP*TP*TP*GP*AP*AP*AP*GP*GP* CP*AP*AP*AP*TP*GP*GP*AP*G)-3', DNA 5'-D(*CP*TP*CP*CP*AP*TP*TP*TP*GP*CP*CP*TP*TP* TP*CP*AP*AP*AP*TP*GP*TP*G)-3'
Authors:Remenyi, A., Tomilin, A., Pohl, E., Scholer, H.R., Wilmanns, M.
Deposit date:2000-11-27
Release date:2001-11-10
Last modified:2012-11-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Differential Dimer Activities of the Transcription Factor Oct-1 by DNA-Induced Interface Swapping
Mol.Cell, 8, 2001
1O4X
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TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT
Descriptor:5'-D(*TP*GP*TP*CP*TP*TP*TP*GP*TP*CP*AP*TP*GP*CP*TP*AP*AP*TP*G)-3', 5'-D(*CP*AP*TP*TP*AP*GP*CP*AP*TP*GP*AP*CP*AP*AP*AP*GP*AP*CP*A)-3', transcription factor Oct-1, ...
Authors:Clore, G.M., Williams, D.C.
Deposit date:2003-07-17
Release date:2004-01-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complex.
J.Biol.Chem., 279, 2004
2XSD
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CRYSTAL STRUCTURE OF THE DIMERIC OCT-6 (POU3F1) POU DOMAIN BOUND TO PALINDROMIC MORE DNA
Descriptor:5'-D(*AP*TP*GP*CP*AP*TP*GP*AP*GP*GP*AP)-3', 5'-D(*CP*CP*TP*CP*AP*TP*GP*CP*AP*TP*AP)-3', POU DOMAIN, ...
Authors:Jauch, R., Choo, S.H., Ng, C.K.L., Kolatkar, P.R.
Deposit date:2010-09-28
Release date:2010-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.049 Å)
Cite:Crystal Structure of the Dimeric Oct6 (POU3F1) POU Domain Bound to Palindromic More DNA.
Proteins, 79, 2011
3D1N
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STRUCTURE OF HUMAN BRN-5 TRANSCRIPTION FACTOR IN COMPLEX WITH CORTICOTROPHIN-RELEASING HORMONE GENE PROMOTER
Descriptor:5'-D(*DAP*DGP*DCP*DAP*DTP*DAP*DAP*DAP*DTP*DAP*DAP*DTP*DAP*DA)-3', 5'-D(*DTP*DTP*DAP*DTP*DTP*DAP*DTP*DTP*DTP*DAP*DTP*DGP*DCP*DT)-3', POU domain, ...
Authors:Pereira, J.H., Ha, S.C., Kim, S.-H.
Deposit date:2008-05-06
Release date:2009-05-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structure of human Brn-5 transcription factor in complex with CRH gene promoter.
J.Struct.Biol., 167, 2009
3L1P
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POU PROTEIN:DNA COMPLEX
Descriptor:POU domain, class 5, transcription factor 1, ...
Authors:Vahokoski, J., Groves, M.R., Pogenberg, V., Wilmanns, M.
Deposit date:2009-12-14
Release date:2010-12-15
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A unique Oct4 interface is crucial for reprogramming to pluripotency
Nat.Cell Biol., 15, 2013
5WC9
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HUMAN PIT-1 AND 4XCATT DNA COMPLEX
Descriptor:Pituitary-specific positive transcription factor 1, DNA (5'-D(*CP*CP*AP*TP*TP*CP*AP*TP*TP*CP*AP*TP*TP*CP*AP*TP*TP*CP*GP*GP*A)-3'), DNA (5'-D(*CP*CP*GP*AP*AP*TP*GP*AP*AP*TP*GP*AP*AP*TP*GP*AP*AP*TP*GP*GP*T)-3')
Authors:Agarwal, S., Cho, T.Y.
Deposit date:2017-06-29
Release date:2017-11-22
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Biochemical and structural characterization of a novel cooperative binding mode by Pit-1 with CATT repeats in the macrophage migration inhibitory factor promoter.
Nucleic Acids Res., 46, 2018
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