Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6X87
DownloadVisualize
BU of 6x87 by Molmil
CryoEM structure of the Plasmodium berghei circumsporozoite protein in complex with inhibitory mouse antibody 3D11.
Descriptor: 3D11 Fab heavy chain, 3D11 Fab kappa chain, Circumsporozoite protein
Authors:Kucharska, I, Thai, E, Rubinstein, J, Julien, J.P.
Deposit date:2020-06-01
Release date:2020-12-02
Last modified:2020-12-16
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural ordering of the Plasmodium berghei circumsporozoite protein repeats by inhibitory antibody 3D11.
Elife, 9, 2020
2BBX
DownloadVisualize
BU of 2bbx by Molmil
NMR solution structure of the TSR domain of malaria TRAP protein
Descriptor: Thrombospondin-related anonymous protein
Authors:Tossavainen, H, Permi, P, Kilpelainen, I.
Deposit date:2005-10-18
Release date:2006-08-08
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:The layered fold of the TSR domain of P. falciparum TRAP contains a heparin binding site.
Protein Sci., 15, 2006
6B0S
DownloadVisualize
BU of 6b0s by Molmil
Crystal structure of circumsporozoite protein aTSR domain in complex with 1710 antibody
Descriptor: 1710 antibody, heavy chain, light chain, ...
Authors:Scally, S.W, Murugan, R, Bosch, A, Triller, G, Wardemann, H, Julien, J.P.
Deposit date:2017-09-15
Release date:2017-11-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection.
J. Exp. Med., 215, 2018
1LSL
DownloadVisualize
BU of 1lsl by Molmil
Crystal Structure of the Thrombospondin-1 Type 1 Repeats
Descriptor: Thrombospondin 1, alpha-L-fucopyranose, beta-L-fucopyranose
Authors:Tan, K, Duquette, M, Liu, J, Dong, Y, Zhang, R, Joachimiak, A, Lawler, J, Wang, J.-H.
Deposit date:2002-05-17
Release date:2002-12-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the TSP-1 type 1 repeats: a novel layered fold and its biological implication.
J.Cell Biol., 159, 2002
7V05
DownloadVisualize
BU of 7v05 by Molmil
Complex of Plasmodium falciparum circumsporozoite protein with 850 Fab
Descriptor: 850 Fab Heavy Chain, 850 Fab Light Chain, Circumsporozoite protein
Authors:Kucharska, I, Prieto, K, Rubinstein, J.L, Julien, J.P.
Deposit date:2022-05-09
Release date:2022-11-23
Last modified:2022-12-14
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire.
Plos Pathog., 18, 2022
8J64
DownloadVisualize
BU of 8j64 by Molmil
Crystal structure of Toxoplasma gondii MIC2-M2AP complex
Descriptor: MIC2-associated protein, Micronemal protein MIC2
Authors:Zhang, S, Wang, F.F, Zhang, D.J, Song, G.J, Springer, T.A.
Deposit date:2023-04-24
Release date:2023-08-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into MIC2 recognition by MIC2-associated protein in Toxoplasma gondii.
Commun Biol, 6, 2023
8OIL
DownloadVisualize
BU of 8oil by Molmil
Plasmodium falciparum circumsporozoite protein C-terminal domain
Descriptor: Circumsporozoite protein
Authors:Sterckx, Y.G.-J, Volkov, A.N, Geens, R.
Deposit date:2023-03-23
Release date:2024-02-28
Method:SOLUTION NMR, SOLUTION SCATTERING
Cite:Plasmodium falciparum circumsporozoite protein C-terminal domain
To Be Published
7YYK
DownloadVisualize
BU of 7yyk by Molmil
Crystal structure of the O-fucosylated form of TSRs1-3 from the human thrombospondin 1
Descriptor: 1,2-ETHANEDIOL, Thrombospondin-1, alpha-L-fucopyranose
Authors:Berardinelli, S.J, Eletsky, A, Valero-Gonzalez, J, Ito, A, Manjunath, R, Hurtado-Guerrero, R, Prestegard, J.R, Woods, R.J, Haltiwanger, R.S.
Deposit date:2022-02-18
Release date:2022-05-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:O-fucosylation stabilizes the TSR3 motif in thrombospondin-1 by interacting with nearby amino acids and protecting a disulfide bond.
J.Biol.Chem., 298, 2022
3R6B
DownloadVisualize
BU of 3r6b by Molmil
Crystal Structure of Thrombospondin-1 TSR Domains 2 and 3
Descriptor: 1,2-ETHANEDIOL, Thrombospondin-1
Authors:Page, R.C, Klenotic, P.A, Misra, S, Silverstein, R.L.
Deposit date:2011-03-21
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Expression, purification and structural characterization of functionally replete thrombospondin-1 type 1 repeats in a bacterial expression system.
Protein Expr.Purif., 80, 2011
7R84
DownloadVisualize
BU of 7r84 by Molmil
Structure of mouse BAI1 (ADGRB1) TSR3 domain in P21 space group
Descriptor: Vasculostatin-120, alpha-D-mannopyranose, beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose
Authors:Miao, Y, Jude, K.M, Garcia, K.C.
Deposit date:2021-06-26
Release date:2021-11-10
Last modified:2022-05-25
Method:X-RAY DIFFRACTION (1.336 Å)
Cite:RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development.
Cell, 184, 2021
7R85
DownloadVisualize
BU of 7r85 by Molmil
Structure of mouse Bai1 (ADGRB1) TSR3 domain
Descriptor: Vasculostatin-120, alpha-D-mannopyranose, beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose
Authors:Miao, Y, Jude, K.M, Garcia, K.C.
Deposit date:2021-06-26
Release date:2021-11-10
Last modified:2022-05-25
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development.
Cell, 184, 2021
1SZL
DownloadVisualize
BU of 1szl by Molmil
F-spondin TSR domain 1
Descriptor: F-spondin
Authors:Tossavainen, H, Paakkonen, K, Permi, P, Kilpelainen, I, Guntert, P.
Deposit date:2004-04-06
Release date:2005-04-19
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structures of the first and fourth TSR domains of F-spondin
Proteins, 64, 2006
1VEX
DownloadVisualize
BU of 1vex by Molmil
F-spondin TSR domain 4
Descriptor: F-spondin
Authors:Paakkonen, K, Tossavainen, H, Permi, P, Kilpelainen, I, Guntert, P.
Deposit date:2004-04-06
Release date:2005-04-19
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structures of the first and fourth TSR domains of F-spondin
Proteins, 64, 2006
7RXJ
DownloadVisualize
BU of 7rxj by Molmil
Fab236 in complex with the C-terminal alpha-TSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab236 heavy chain, Fab236 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-23
Release date:2022-03-16
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (2.345 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7S0X
DownloadVisualize
BU of 7s0x by Molmil
Fab352 in complex with the C-terminal alphaTSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab352 heavy chain, Fab352 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-31
Release date:2022-03-16
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7RXP
DownloadVisualize
BU of 7rxp by Molmil
Fab1512 in complex with the C-terminal alpha-TSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab1512 heavy chain, Fab1512 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-23
Release date:2022-03-16
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (1.761 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7RXI
DownloadVisualize
BU of 7rxi by Molmil
Fab234 in complex with the C-terminal alpha-TSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab234 heavy chain, Fab234 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-23
Release date:2022-03-16
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7RXL
DownloadVisualize
BU of 7rxl by Molmil
Fab1488 in complex with the C-terminal alpha-TSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab1488 heavy chain, Fab1488 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-23
Release date:2022-03-16
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (1.823 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
3VDJ
DownloadVisualize
BU of 3vdj by Molmil
Crystal structure of circumsporozoite protein aTSR domain, R32 native form
Descriptor: Circumsporozoite (CS) protein
Authors:Doud, M.B, Koksal, A.C, Mi, L.Z, Song, G, Lu, C, Springer, T.A.
Deposit date:2012-01-05
Release date:2012-05-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Unexpected fold in the circumsporozoite protein target of malaria vaccines.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VDK
DownloadVisualize
BU of 3vdk by Molmil
Crystal structure of circumsporozoite protein aTSR domain, R32 platinum-bound form
Descriptor: Circumsporozoite (CS) protein, PLATINUM (II) ION
Authors:Doud, M.B, Koksal, A.C, Mi, L.Z, Song, G, Lu, C, Springer, T.A.
Deposit date:2012-01-05
Release date:2012-05-09
Last modified:2012-05-30
Method:X-RAY DIFFRACTION (1.847 Å)
Cite:Unexpected fold in the circumsporozoite protein target of malaria vaccines.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VDL
DownloadVisualize
BU of 3vdl by Molmil
Crystal structure of circumsporozoite protein aTSR domain, P43212 form
Descriptor: Circumsporozoite (CS) protein
Authors:Doud, M.B, Koksal, A.C, Mi, L.Z, Song, G, Lu, C, Springer, T.A.
Deposit date:2012-01-05
Release date:2012-05-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Unexpected fold in the circumsporozoite protein target of malaria vaccines.
Proc.Natl.Acad.Sci.USA, 109, 2012
8EH5
DownloadVisualize
BU of 8eh5 by Molmil
Cryo-EM structure of L9 Fab in complex with rsCSP
Descriptor: Circumsporozoite protein, L9 Heavy chain, L9 Light chain
Authors:Martin, G.M, Ward, A.B.
Deposit date:2022-09-13
Release date:2023-06-28
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Structural basis of epitope selectivity and potent protection from malaria by PfCSP antibody L9.
Nat Commun, 14, 2023
8EKA
DownloadVisualize
BU of 8eka by Molmil
Cryo-EM structure of a potent anti-malarial antibody L9 in complex with Plasmodium falciparum circumsporozoite protein (PfCSP)(class 2)
Descriptor: Circumsporozoite protein, L9 Fab heavy chain, L9 Fab light chain
Authors:Tripathi, P, Kwong, P.D.
Deposit date:2022-09-20
Release date:2023-03-15
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structures of anti-malarial antibody L9 with circumsporozoite protein reveal trimeric L9 association and complete 27-residue epitope.
Structure, 31, 2023
8EK1
DownloadVisualize
BU of 8ek1 by Molmil
Cryo-EM structure of a potent anti-malarial antibody L9 in complex with Plasmodium falciparum circumsporozoite protein (PfCSP)(dominant class)
Descriptor: Circumsporozoite protein, L9 Fab heavy chain, L9 Fab light chain
Authors:Tripathi, P, Kwong, P.D.
Deposit date:2022-09-19
Release date:2023-03-15
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures of anti-malarial antibody L9 with circumsporozoite protein reveal trimeric L9 association and complete 27-residue epitope.
Structure, 31, 2023
8DYX
DownloadVisualize
BU of 8dyx by Molmil
Cryo-EM structure of 311 Fab in complex with recombinant shortened Plasmodium falciparum circumsporozoite protein (rsCSP)
Descriptor: 311 heavy chain, 311 light chain, Circumsporozoite protein
Authors:Martin, G.M, Ward, A.B.
Deposit date:2022-08-05
Release date:2023-08-02
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Spectrum of PfCSP-antibody cryo-EM structures and the role of homotypic interactions
To Be Published

 

1234>

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon