1NMB
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THE STRUCTURE OF A COMPLEX BETWEEN THE NC10 ANTIBODY AND INFLUENZA VIRUS NEURAMINIDASE AND COMPARISON WITH THE OVERLAPPING BINDING SITE OF THE NC41 ANTIBODY
Descriptor:N9 NEURAMINIDASE, FAB NC10
Authors:Malby, R.L., Tulip, W.R., Colman, P.M.
Deposit date:1995-01-17
Release date:1995-09-15
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of a complex between the NC10 antibody and influenza virus neuraminidase and comparison with the overlapping binding site of the NC41 antibody
Structure, 2, 1994
2HT5
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N8 NEURAMINIDASE
Descriptor:Neuraminidase (E.C.3.2.1.18)
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-25
Release date:2006-09-05
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HT7
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N8 NEURAMINIDASE IN OPEN COMPLEX WITH OSELTAMIVIR
Descriptor:Neuraminidase (E.C.3.2.1.18)
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-25
Release date:2006-09-05
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HT8
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N8 NEURAMINIDASE IN COMPLEX WITH OSELTAMIVIR
Descriptor:Neuraminidase (E.C.3.2.1.18)
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-25
Release date:2006-09-05
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HTQ
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N8 NEURAMINIDASE IN COMPLEX WITH ZANAMIVIR
Descriptor:Neuraminidase (E.C.3.2.1.18)
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-26
Release date:2006-09-05
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HTR
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N8 NEURAMINIDASE IN COMPLEX WITH DANA
Descriptor:Neuraminidase (E.C.3.2.1.18)
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-26
Release date:2006-09-05
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HTU
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N8 NEURAMINIDASE IN COMPLEX WITH PERAMIVIR
Descriptor:Neuraminidase (E.C.3.2.1.18)
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-26
Release date:2006-09-05
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HTY
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N1 NEURAMINIDASE
Descriptor:Neuraminidase
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-26
Release date:2006-09-05
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HU0
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N1 NEURAMINIDASE IN COMPLEX WITH OSELTAMIVIR 1
Descriptor:Neuraminidase
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-26
Release date:2006-09-05
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HU4
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N1 NEURAMINIDASE IN COMPLEX WITH OSELTAMIVIR 2
Descriptor:Neuraminidase
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-26
Release date:2006-09-05
Modification date:2012-05-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
3B7E
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NEURAMINIDASE OF A/BREVIG MISSION/1/1918 H1N1 STRAIN IN COMPLEX WITH ZANAMIVIR
Descriptor:Neuraminidase (E.C.3.2.1.18)
Authors:Xu, X., Zhu, X., Wilson, I.A.
Deposit date:2007-10-30
Release date:2008-10-07
Modification date:2011-10-12
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural characterization of the 1918 influenza virus H1N1 neuraminidase
J.Virol., 82, 2008
3BEQ
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NEURAMINIDASE OF A/BREVIG MISSION/1/1918 H1N1 STRAIN
Descriptor:Neuraminidase (E.C.3.2.1.18)
Authors:Xu, X., Zhu, X., Wilson, I.A.
Deposit date:2007-11-19
Release date:2008-09-30
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Structural characterization of the 1918 influenza virus H1N1 neuraminidase
J.Virol., 82, 2008
3CKZ
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N1 NEURAMINIDASE H274Y + ZANAMIVIR
Descriptor:Neuraminidase (E.C.3.2.1.18)
Authors:Colllins, P., Haire, L.F., Lin, Y.P., Liu, J., Russell, R.J., Walker, P.A., Skehel, J.J., Martin, S.R., Hay, A.J., Gamblin, S.J.
Deposit date:2008-03-18
Release date:2008-05-20
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Nature, 453, 2008
3CL0
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N1 NEURAMINIDASE H274Y + OSELTAMIVIR
Descriptor:Neuraminidase (E.C.3.2.1.18)
Authors:Collins, P., Haire, L.F., Lin, Y.P., Liu, J., Russell, R.J., Walker, P.A., Skehel, J.J., Martin, S.R., Hay, A.J., Gamblin, S.J.
Deposit date:2008-03-18
Release date:2008-05-20
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Nature, 453, 2008
3CL2
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N1 NEURAMINIDASE N294S + OSELTAMIVIR
Descriptor:Neuraminidase (E.C.3.2.1.18)
Authors:Collins, P., Haire, L.F., Lin, Y.P., Liu, J., Russell, R.J., Walker, P.A., Skehel, J.J., Martin, S.R., Hay, A.J., Gamblin, S.J.
Deposit date:2008-03-18
Release date:2008-05-20
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.538 Å)
Cite:Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Nature, 453, 2008
3CYE
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CYRSTAL STRUCTURE OF THE NATIVE 1918 H1N1 NEURAMINIDASE FROM A CRYSTAL WITH LATTICE-TRANSLOCATION DEFECTS
Descriptor:Neuraminidase (E.C.3.2.1.18)
Authors:Zhu, X., Xu, X., Wilson, I.A.
Deposit date:2008-04-25
Release date:2008-08-05
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure determination of the 1918 H1N1 neuraminidase from a crystal with lattice-translocation defects
Acta Crystallogr.,Sect.D, 64, 2008
3NSS
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THE 2009 PANDEMIC H1N1 NEURAMINIDASE N1 LACKS THE 150-CAVITY IN ITS ACTIVE SITES
Descriptor:Neuraminidase
Authors:Li, Q., Qi, J.X., Zhang, W., Vavricka, C.J., Shi, Y., Gao, G.F.
Deposit date:2010-07-02
Release date:2010-09-22
Modification date:2014-02-26
Method:X-RAY DIFFRACTION (1.902 Å)
Cite:The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site
Nat.Struct.Mol.Biol., 17, 2010
3O9J
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INFLUENZA NA IN COMPLEX WITH COMPOUND 5
Descriptor:Neuraminidase (E.C.3.2.1.18)
Authors:Russell, R.J., Kerry, P.S.
Deposit date:2010-08-04
Release date:2010-12-15
Method:X-RAY DIFFRACTION (2.0002 Å)
Cite:Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase.
Nat Commun, 1, 2010
3O9K
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INFLUENZA NA IN COMPLEX WITH COMPOUND 6
Descriptor:Neuraminidase (E.C.3.2.1.18)
Authors:Russell, R.J., Kerry, P.S.
Deposit date:2010-08-04
Release date:2010-12-15
Method:X-RAY DIFFRACTION (2.4945 Å)
Cite:Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase.
Nat Commun, 1, 2010
3TI3
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CRYSTAL STRUCTURE OF 2009 PANDEMIC H1N1 NEURAMINIDASE COMPLEXED WITH LANINAMIVIR
Descriptor:Neuraminidase
Authors:Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F.
Deposit date:2011-08-20
Release date:2011-11-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
3TI4
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CRYSTAL STRUCTURE OF 2009 PANDEMIC H1N1 NEURAMINIDASE COMPLEXED WITH LANINAMIVIR OCTANOATE
Descriptor:Neuraminidase
Authors:Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F.
Deposit date:2011-08-20
Release date:2011-11-16
Method:X-RAY DIFFRACTION (1.602 Å)
Cite:Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
3TI5
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CRYSTAL STRUCTURE OF 2009 PANDEMIC H1N1 NEURAMINIDASE COMPLEXED WITH ZANAMIVIR
Descriptor:Neuraminidase
Authors:Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F.
Deposit date:2011-08-20
Release date:2011-11-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
3TI6
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CRYSTAL STRUCTURE OF 2009 PANDEMIC H1N1 NEURAMINIDASE COMPLEXED WITH OSELTAMIVIR
Descriptor:Neuraminidase
Authors:Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F.
Deposit date:2011-08-20
Release date:2011-11-23
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
3TIA
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CRYSTAL STRUCTURE OF 1957 PANDEMIC H2N2 NEURAMINIDASE COMPLEXED WITH LANINAMIVIR
Descriptor:Neuraminidase
Authors:Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F.
Deposit date:2011-08-20
Release date:2011-11-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
3TIB
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CRYSTAL STRUCTURE OF 1957 PANDEMIC H2N2 NEURAMINIDASE COMPLEXED WITH LANINAMIVIR OCTANOATE
Descriptor:Neuraminidase
Authors:Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F.
Deposit date:2011-08-20
Release date:2011-11-16
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
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