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8GC4
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BU of 8gc4 by Molmil
Domoate-bound GluK2 kainate receptor in partially-open conformation 3
Descriptor: (2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-METHYL-1,3-HEXADIENYL]-3-PYRROLIDINEACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Bogdanovic, N, Tajima, N.
Deposit date:2023-03-01
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.93 Å)
Cite:Structural basis for kainate receptor activation by a partial agonist
To Be Published
8GC2
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BU of 8gc2 by Molmil
Domoate-bound GluK2 kainate receptor in partially-open conformation 1
Descriptor: (2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-METHYL-1,3-HEXADIENYL]-3-PYRROLIDINEACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Bogdanovic, N, Tajima, N.
Deposit date:2023-03-01
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis for kainate receptor activation by a partial agonist
To Be Published
8GC5
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BU of 8gc5 by Molmil
Domoate-bound GluK2 kainate receptors in non-active conformation
Descriptor: (2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-METHYL-1,3-HEXADIENYL]-3-PYRROLIDINEACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Bogdanovic, N, Tajima, N.
Deposit date:2023-03-01
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.93 Å)
Cite:Structural basis for kainate receptor activation by a partial agonist
To Be Published
8GC3
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BU of 8gc3 by Molmil
Domote-bound GluK2 kainate receptors in partially-open conformation 2
Descriptor: (2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-METHYL-1,3-HEXADIENYL]-3-PYRROLIDINEACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Bogdanovic, N, Tajima, N.
Deposit date:2023-03-01
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis for kainate receptor activation by a partial agonist
To Be Published
8FQA
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BU of 8fqa by Molmil
LBD conformation 2 (LBDconf2) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Na110)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-03-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FPZ
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BU of 8fpz by Molmil
LBD conformation 3 (LBDconf3) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 500mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na610)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-03-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FPV
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BU of 8fpv by Molmil
LBD conformation 1 (LBDconf1) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 500mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na610)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-03-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FPY
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BU of 8fpy by Molmil
LBD conformation 2 (LBDconf2) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 500mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na610)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-03-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FP9
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BU of 8fp9 by Molmil
GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg)
Descriptor: CALCIUM ION, CHLORIDE ION, Glutamate receptor 2, ...
Authors:Nakagawa, T.
Deposit date:2023-01-04
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.44 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FPH
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BU of 8fph by Molmil
Conformation 2 of the ligand binding domain (LBDconf2) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-04
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FQ8
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BU of 8fq8 by Molmil
LBD conformation 1 (LBDconf1) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Na110)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FPL
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BU of 8fpl by Molmil
LBD conformation 2 (LBDconf2) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100uM CNQX (Closed-CaNaMg)
Descriptor: 6-(aminomethyl)-7-nitro-1,4-dihydroquinoxaline-2,3-dione, CYCLOTHIAZIDE, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-04
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FPS
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BU of 8fps by Molmil
GluA2 flip Q isoform N619K mutant of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg/N619K)
Descriptor: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.38 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FQG
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BU of 8fqg by Molmil
LBD conformation 1 (LBDconf1) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 150mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na260)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-06
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FQB
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BU of 8fqb by Molmil
GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 10mM CaCl2, 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Ca10)
Descriptor: CALCIUM ION, CHLORIDE ION, Glutamate receptor 2, ...
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.36 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FQ2
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BU of 8fq2 by Molmil
LBD conformation 1 (LBDconf1) of GluA2 flip Q isoform N619K mutant of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg/N619K)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FR0
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BU of 8fr0 by Molmil
LBD conformation 3 (LBDconf3) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 150mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na260)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-06
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FPC
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BU of 8fpc by Molmil
Conformation 1 of the ligand binding domain (LBDconf1) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-04
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.78 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FQ1
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BU of 8fq1 by Molmil
GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 150mM CaCl2, 330uM CTZ, and 100mM L-glutamate (Open-Ca150)
Descriptor: CALCIUM ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (5.59 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FP4
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BU of 8fp4 by Molmil
GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 500mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na610)
Descriptor: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Nakagawa, T.
Deposit date:2023-01-04
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FQ6
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BU of 8fq6 by Molmil
LBD of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 150mM CaCl2, 330uM CTZ, and 100mM L-glutamate (Open-Ca150)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FQ5
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BU of 8fq5 by Molmil
GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Na110)
Descriptor: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.34 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FQD
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BU of 8fqd by Molmil
LBD conformation 1 (LBDconf1) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 10mM CaCl2, 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Ca10)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-06
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FPK
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BU of 8fpk by Molmil
LBD conformation 1 of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100uM CNQX (Closed-CaNaMg)
Descriptor: 6-(aminomethyl)-7-nitro-1,4-dihydroquinoxaline-2,3-dione, CYCLOTHIAZIDE, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-04
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024
8FQF
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BU of 8fqf by Molmil
GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 150mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na260)
Descriptor: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Nakagawa, T.
Deposit date:2023-01-06
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.29 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 2024

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PDB entries from 2024-03-27

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