8GC4
| Domoate-bound GluK2 kainate receptor in partially-open conformation 3 | Descriptor: | (2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-METHYL-1,3-HEXADIENYL]-3-PYRROLIDINEACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Bogdanovic, N, Tajima, N. | Deposit date: | 2023-03-01 | Release date: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.93 Å) | Cite: | Structural basis for kainate receptor activation by a partial agonist To Be Published
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8GC2
| Domoate-bound GluK2 kainate receptor in partially-open conformation 1 | Descriptor: | (2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-METHYL-1,3-HEXADIENYL]-3-PYRROLIDINEACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Bogdanovic, N, Tajima, N. | Deposit date: | 2023-03-01 | Release date: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural basis for kainate receptor activation by a partial agonist To Be Published
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8GC5
| Domoate-bound GluK2 kainate receptors in non-active conformation | Descriptor: | (2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-METHYL-1,3-HEXADIENYL]-3-PYRROLIDINEACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Bogdanovic, N, Tajima, N. | Deposit date: | 2023-03-01 | Release date: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.93 Å) | Cite: | Structural basis for kainate receptor activation by a partial agonist To Be Published
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8GC3
| Domote-bound GluK2 kainate receptors in partially-open conformation 2 | Descriptor: | (2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-METHYL-1,3-HEXADIENYL]-3-PYRROLIDINEACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Bogdanovic, N, Tajima, N. | Deposit date: | 2023-03-01 | Release date: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis for kainate receptor activation by a partial agonist To Be Published
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8FQA
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8FPZ
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8FPV
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8FPY
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8FP9
| GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg) | Descriptor: | CALCIUM ION, CHLORIDE ION, Glutamate receptor 2, ... | Authors: | Nakagawa, T. | Deposit date: | 2023-01-04 | Release date: | 2024-02-28 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.44 Å) | Cite: | The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 2024
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8FPH
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8FQ8
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8FPL
| LBD conformation 2 (LBDconf2) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100uM CNQX (Closed-CaNaMg) | Descriptor: | 6-(aminomethyl)-7-nitro-1,4-dihydroquinoxaline-2,3-dione, CYCLOTHIAZIDE, Glutamate receptor 2 | Authors: | Nakagawa, T. | Deposit date: | 2023-01-04 | Release date: | 2024-02-28 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.81 Å) | Cite: | The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 2024
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8FPS
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8FQG
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8FQB
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8FQ2
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8FR0
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8FPC
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8FQ1
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8FP4
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8FQ6
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8FQ5
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8FQD
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8FPK
| LBD conformation 1 of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100uM CNQX (Closed-CaNaMg) | Descriptor: | 6-(aminomethyl)-7-nitro-1,4-dihydroquinoxaline-2,3-dione, CYCLOTHIAZIDE, Glutamate receptor 2 | Authors: | Nakagawa, T. | Deposit date: | 2023-01-04 | Release date: | 2024-02-28 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 2024
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8FQF
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