3KG2
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AMPA SUBTYPE IONOTROPIC GLUTAMATE RECEPTOR IN COMPLEX WITH COMPETITIVE ANTAGONIST ZK 200775
Descriptor:Glutamate receptor 2, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Sobolevsky, A.I., Rosconi, M.P., Gouaux, E.
Deposit date:2009-10-28
Release date:2009-12-08
Last modified:2015-05-27
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor.
Nature, 462, 2009
4PE5
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CRYSTAL STRUCTURE OF GLUN1A/GLUN2B NMDA RECEPTOR ION CHANNEL
Descriptor:Glutamate receptor ionotropic, NMDA 1, NMDA 2B, ...
Authors:Karakas, E., Furukawa, H.
Deposit date:2014-04-22
Release date:2014-06-04
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (3.96 Å)
Cite:Crystal structure of a heterotetrameric NMDA receptor ion channel.
Science, 344, 2014
4TLL
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CRYSTAL STRUCTURE OF GLUN1/GLUN2B NMDA RECEPTOR, STRUCTURE 1
Descriptor:receptor subunit GluN1, receptor subunit GluN2B, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Gouaux, E., Lee, C.-H., Lu, W.
Deposit date:2014-05-30
Release date:2014-07-02
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (3.59 Å)
Cite:NMDA receptor structures reveal subunit arrangement and pore architecture.
Nature, 511, 2014
4TLM
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CRYSTAL STRUCTURE OF GLUN1/GLUN2B NMDA RECEPTOR, STRUCTURE 2
Descriptor:receptor subunit GluN1, receptor subunit GluN2B, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Gouaux, E., Lee, C.-H., Lu, W.
Deposit date:2014-05-30
Release date:2014-07-02
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (3.77 Å)
Cite:NMDA receptor structures reveal subunit arrangement and pore architecture.
Nature, 511, 2014
4U1W
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FULL LENGTH GLUA2-KAINATE-(R,R)-2B COMPLEX CRYSTAL FORM A
Descriptor:Glutamate receptor 2, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Chen, L., Gouaux, E.
Deposit date:2014-07-16
Release date:2014-08-20
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
4U1X
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FULL LENGTH GLUA2-KAINATE-(R,R)-2B COMPLEX CRYSTAL FORM B
Descriptor:Glutamate receptor 2, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Chen, L., Gouaux, E.
Deposit date:2014-07-16
Release date:2014-08-20
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.301 Å)
Cite:Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
4U1Y
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FULL LENGTH GLUA2-FW-(R,R)-2B COMPLEX
Descriptor:Glutamate receptor 2, N-ACETYL-D-GLUCOSAMINE, 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, ...
Authors:Chen, L., Gouaux, E.
Deposit date:2014-07-16
Release date:2014-08-20
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.8999 Å)
Cite:Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
4U2P
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FULL-LENGTH AMPA SUBTYPE IONOTROPIC GLUTAMATE RECEPTOR GLUA2 IN THE APO STATE
Descriptor:Glutamate receptor 2, N-ACETYL-D-GLUCOSAMINE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Duerr, K.L., Gouaux, E.
Deposit date:2014-07-17
Release date:2014-08-20
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.2386 Å)
Cite:Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
4U2Q
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FULL-LENGTH AMPA SUBTYPE IONOTROPIC GLUTAMATE RECEPTOR GLUA2 IN COMPLEX WITH PARTIAL AGONIST KAINATE
Descriptor:Glutamate receptor 2, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, N-ACETYL-D-GLUCOSAMINE
Authors:Duerr, K.L., Chen, L., Gouaux, E.
Deposit date:2014-07-17
Release date:2014-08-20
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.5247 Å)
Cite:Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
4U4F
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STRUCTURE OF GLUA2* IN COMPLEX WITH PARTIAL AGONIST (S)-5-NITROWILLARDIINE
Descriptor:Glutamate receptor 2, N-ACETYL-D-GLUCOSAMINE, 3-(5-nitro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-L-alanine
Authors:Yelshanskaya, M.V., Li, M., Sobolevsky, A.I.
Deposit date:2014-07-23
Release date:2014-08-27
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (4.79 Å)
Cite:Structure of an agonist-bound ionotropic glutamate receptor.
Science, 345, 2014
4U4G
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STRUCTURE OF GLUA2* IN COMPLEX WITH COMPETITIVE ANTAGONIST ZK 200775
Descriptor:Glutamate receptor 2, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Yelshanskaya, M.V., Li, M., Sobolevsky, A.I.
Deposit date:2014-07-23
Release date:2014-10-22
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (4.49 Å)
Cite:Structure of an agonist-bound ionotropic glutamate receptor.
Science, 345, 2014
4U5B
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CRYSTAL STRUCTURE OF GLUA2 A622T, CON-IKOT-IKOT SNAIL TOXIN, PARTIAL AGONIST KA AND POSTITIVE MODULATOR (R,R)-2B COMPLEX
Descriptor:Glutamate receptor 2, Con-ikot-ikot, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, ...
Authors:Chen, L., Gouaux, E.
Deposit date:2014-07-25
Release date:2014-08-13
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.5037 Å)
Cite:X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism.
Science, 345, 2014
4U5C
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CRYSTAL STRUCTURE OF GLUA2, CON-IKOT-IKOT SNAIL TOXIN, PARTIAL AGONIST FW AND POSTITIVE MODULATOR (R,R)-2B COMPLEX
Descriptor:Glutamate receptor 2, Con-ikot-ikot, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Chen, L., Gouaux, E.
Deposit date:2014-07-25
Release date:2014-08-13
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.6883 Å)
Cite:X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism.
Science, 345, 2014
4U5D
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CRYSTAL STRUCTURE OF GLUA2, CON-IKOT-IKOT SNAIL TOXIN, PARTIAL AGONIST KA AND POSTITIVE MODULATOR (R,R)-2B COMPLEX
Descriptor:Glutamate receptor 2, Con-ikot-ikot, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, ...
Authors:Chen, L., Gouaux, E.
Deposit date:2014-07-25
Release date:2014-08-13
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.5757 Å)
Cite:X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism.
Science, 345, 2014
4U5E
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CRYSTAL STRUCTURE OF GLUA2 T625G, CON-IKOT-IKOT SNAIL TOXIN, PARTIAL AGONIST KA AND POSTITIVE MODULATOR (R,R)-2B COMPLEX
Descriptor:Glutamate receptor 2, Con-ikot-ikot, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, ...
Authors:Chen, L., Gouaux, E.
Deposit date:2014-07-25
Release date:2014-08-13
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.5073 Å)
Cite:X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism.
Science, 345, 2014
4U5F
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CRYSTAL STRUCTURE OF GLUA2, CON-IKOT-IKOT SNAIL TOXIN, PARTIAL AGONIST KA AND POSTITIVE MODULATOR (R,R)-2B COMPLEX, GLUA2CRYST2 CONSTRUCT
Descriptor:Glutamate receptor 2, Con-ikot-ikot, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, ...
Authors:Chen, L., Gouaux, E.
Deposit date:2014-07-24
Release date:2014-08-13
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism.
Science, 345, 2014
4UQ6
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ELECTRON DENSITY MAP OF GLUA2EM IN COMPLEX WITH LY451646 AND GLUTAMATE
Descriptor:GLUTAMATE RECEPTOR 2, GLUTAMIC ACID
Authors:Meyerson, J.R., Kumar, J., Chittori, S., Rao, P., Pierson, J., Bartesaghi, A., Mayer, M.L., Subramaniam, S.
Deposit date:2014-06-20
Release date:2014-08-13
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (12.8 Å)
Cite:Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014
4UQJ
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CRYO-EM DENSITY MAP OF GLUA2EM IN COMPLEX WITH ZK200775
Descriptor:GLUTAMATE RECEPTOR 2, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
Authors:Meyerson, J.R., Kumar, J., Chittori, S., Rao, P., Pierson, J., Bartesaghi, A., Mayer, M.L., Subramaniam, S.
Deposit date:2014-06-24
Release date:2014-08-13
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (10.4 Å)
Cite:Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014
4UQK
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ELECTRON DENSITY MAP OF GLUA2EM IN COMPLEX WITH QUISQUALATE AND LY451646
Descriptor:GLUTAMATE RECEPTOR 2, (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID
Authors:Meyerson, J.R., Kumar, J., Chittori, S., Rao, P., Pierson, J., Bartesaghi, A., Mayer, M.L., Subramaniam, S.
Deposit date:2014-06-24
Release date:2014-08-13
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (16.4 Å)
Cite:Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014
4UQQ
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ELECTRON DENSITY MAP OF GLUK2 DESENSITIZED STATE IN COMPLEX WITH 2S,4R-4-METHYLGLUTAMATE
Descriptor:GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 2, GLUTAMIC ACID
Authors:Meyerson, J.R., Kumar, J., Chittori, S., Rao, P., Pierson, J., Bartesaghi, A., Mayer, M.L., Subramaniam, S.
Deposit date:2014-06-24
Release date:2014-08-13
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014
5FXG
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GLUN1B-GLUN2B NMDA RECEPTOR IN ACTIVE CONFORMATION
Descriptor:N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B
Authors:Tajima, N., Karakas, E., Grant, T., Simorowski, N., Diaz-Avalos, R., Grigorieff, N., Furukawa, H.
Deposit date:2016-03-02
Release date:2016-05-11
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil.
Nature, 534, 2016
5FXH
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GLUN1B-GLUN2B NMDA RECEPTOR IN NON-ACTIVE-1 CONFORMATION
Descriptor:N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B
Authors:Tajima, N., Karakas, E., Grant, T., Simorowski, N., Diaz-Avalos, R., Grigorieff, N., Furukawa, H.
Deposit date:2016-03-02
Release date:2016-05-11
Last modified:2017-04-19
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil.
Nature, 534, 2016
5FXI
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GLUN1B-GLUN2B NMDA RECEPTOR STRUCTURE IN NON-ACTIVE-2 CONFORMATION
Descriptor:N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B
Authors:Tajima, N., Karakas, E., Grant, T., Simorowski, N., Diaz-Avalos, R., Grigorieff, N., Furukawa, H.
Deposit date:2016-03-02
Release date:2016-05-11
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil.
Nature, 534, 2016
5FXJ
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GLUN1B-GLUN2B NMDA RECEPTOR STRUCTURE-CLASS X
Descriptor:GLUTAMATE RECEPTOR IONOTROPIC, NMDA 1, NMDA 2B
Authors:Tajima, N., Karakas, E., Grant, T., Simorowski, N., Diaz-Avalos, R., Grigorieff, N., Furukawa H, H.
Deposit date:2016-03-02
Release date:2016-05-25
Last modified:2016-06-15
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil.
Nature, 534, 2016
5FXK
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GLUN1B-GLUN2B NMDA RECEPTOR STRUCTURE-CLASS Y
Descriptor:N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B
Authors:Tajima, N., Karakas, E., Grant, T., Simorowski, N., Diaz-Avalos, R., Grigorieff, N., Furukawa, H.
Deposit date:2016-03-02
Release date:2016-05-11
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil.
Nature, 534, 2016
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