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6QRI
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BU of 6qri by Molmil
Structure of rabbit G-actin in complex with chivosazole A
Descriptor: (2~{R},3~{R},5~{S},6~{E},8~{E},10~{Z},12~{S},13~{R},16~{Z},18~{E},20~{Z},22~{E},24~{R},25~{S},26~{E},28~{Z})-13-[(2~{S},3~{S},5~{S})-3,5-bis(oxidanyl)hexan-2-yl]-25-[(2~{R},3~{R},4~{S},5~{R},6~{R})-3,4-dimethoxy-6-methyl-5-oxidanyl-oxan-2-yl]oxy-3-methoxy-2,12,22,24-tetramethyl-5-oxidanyl-14,32-dioxa-33-azabicyclo[28.2.1]tritriaconta-1(33),6,8,10,16,18,20,22,26,28,30-undecaen-15-one, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Schneider, S, Wang, S, Zahler, S.
Deposit date:2019-02-19
Release date:2019-07-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Chivosazole A Modulates Protein-Protein Interactions of Actin.
J.Nat.Prod., 82, 2019
5JLF
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BU of 5jlf by Molmil
Structure of the F-actin-tropomyosin complex (Reprocessed)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:von der Ecken, J, Raunser, S.
Deposit date:2016-04-27
Release date:2016-06-15
Last modified:2020-02-12
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution.
Nature, 534, 2016
4WYB
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BU of 4wyb by Molmil
Structure of the Bud6 flank domain in complex with actin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Eck, M.J, Park, E, Zheng, W.
Deposit date:2014-11-17
Release date:2015-08-19
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.493 Å)
Cite:Structure of a Bud6/Actin Complex Reveals a Novel WH2-like Actin Monomer Recruitment Motif.
Structure, 23, 2015
1WUA
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BU of 1wua by Molmil
The structure of Aplyronine A-actin complex
Descriptor: (8R,9R,10R,11R,14S,18S,20S,24S)-24-{(1R,2S,3R,6R,7R,8R,9S,10E)-8-(ACETYLOXY)-6-[(N,N-DIMETHYLALANYL)OXY]-11-[FORMYL(MET HYL)AMINO]-2-HYDROXY-1,3,7,9-TETRAMETHYLUNDEC-10-ENYL}-10-HYDROXY-14,20-DIMETHOXY-9,11,15,18-TETRAMETHYL-2-OXOOXACYCLOTE TRACOSA-3,5,15,21-TETRAEN-8-YL N,N,O-TRIMETHYLSERINATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Hirata, K, Muraoka, S, Suenaga, K, Kuroda, T, Kato, K, Tanaka, H, Yamamoto, M, Takata, M, Yamada, K, Kigoshi, H.
Deposit date:2004-12-03
Release date:2006-02-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure basis for antitumor effect of aplyronine a
J.Mol.Biol., 356, 2006
4K43
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BU of 4k43 by Molmil
Crystal structure of actin in complex with synthetic AplC tail analogue GC04 [N-{(1E,4R,5R,7E,9S,10S,11S)-4,10-dimethoxy-11-[(2S,4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]-5,9-dimethyl-6-oxododeca-1,7-dien-1-yl}-N-methylformamide]
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Pereira, J.H, Petchprayoon, C, Moriarty, N.W, Fink, S.J, Cecere, G, Paterson, I, Adams, P.D, Marriott, G.
Deposit date:2013-04-11
Release date:2014-10-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and biochemical studies of actin in complex with synthetic macrolide tail analogues.
Chemmedchem, 9, 2014
5OGW
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BU of 5ogw by Molmil
Cryo-EM structure of jasplakinolide-stabilized malaria parasite F-actin at near-atomic resolution
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin-1, Jasplakinolide, ...
Authors:Pospich, S, Kumpula, E.-P, von der Ecken, J, Vahokoski, J, Kursula, I, Raunser, S.
Deposit date:2017-07-13
Release date:2017-09-27
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Near-atomic structure of jasplakinolide-stabilized malaria parasite F-actin reveals the structural basis of filament instability.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5OOE
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BU of 5ooe by Molmil
Cryo-EM structure of F-actin in complex with AppNHp (AMPPNP)
Descriptor: Actin, alpha skeletal muscle, MAGNESIUM ION, ...
Authors:Merino, F, Pospich, S, Funk, J, Kuellmer, F, Arndt, H.-D, Bieling, P, Raunser, S.
Deposit date:2017-08-07
Release date:2018-06-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM.
Nat. Struct. Mol. Biol., 25, 2018
5OOD
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BU of 5ood by Molmil
Cryo-EM structure of jasplakinolide-stabilized F-actin in complex with ADP-Pi
Descriptor: (4~{R},7~{R},10~{S},13~{S},15~{E},19~{S})-10-(4-azanylbutyl)-4-(4-hydroxyphenyl)-7-(1~{H}-indol-3-ylmethyl)-8,13,15,19-tetramethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone, ADENOSINE-5'-DIPHOSPHATE, Actin, ...
Authors:Merino, F, Pospich, S, Funk, J, Kuellmer, F, Arndt, H.-D, Bieling, P, Raunser, S.
Deposit date:2017-08-07
Release date:2018-06-13
Last modified:2019-12-04
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM.
Nat. Struct. Mol. Biol., 25, 2018
5ONV
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BU of 5onv by Molmil
Cryo-EM structure of F-actin in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Merino, F, Pospich, S, Funk, J, Kuellmer, F, Arndt, H.-D, Bieling, P, Raunser, S.
Deposit date:2017-08-04
Release date:2018-06-13
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM.
Nat. Struct. Mol. Biol., 25, 2018
5OOC
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BU of 5ooc by Molmil
Cryo-EM structure of jasplakinolide-stabilized F-actin in complex with ADP
Descriptor: (4~{R},7~{R},10~{S},13~{S},15~{E},19~{S})-10-(4-azanylbutyl)-4-(4-hydroxyphenyl)-7-(1~{H}-indol-3-ylmethyl)-8,13,15,19-tetramethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone, ADENOSINE-5'-DIPHOSPHATE, Actin, ...
Authors:Merino, F, Pospich, S, Funk, J, Kuellmer, F, Arndt, H.-D, Bieling, P, Raunser, S.
Deposit date:2017-08-07
Release date:2018-06-13
Last modified:2019-10-16
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM.
Nat. Struct. Mol. Biol., 25, 2018
5OOF
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BU of 5oof by Molmil
Cryo-EM structure of F-actin in complex with ADP-BeFx
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Merino, F, Pospich, S, Funk, J, Kuellmer, F, Arndt, H.-D, Bieling, P, Raunser, S.
Deposit date:2017-08-07
Release date:2018-06-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM.
Nat. Struct. Mol. Biol., 25, 2018
4M63
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BU of 4m63 by Molmil
Crystal Structure of a Filament-Like Actin Trimer Bound to the Bacterial Effector VopL
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION, ...
Authors:Tomchick, D.R, Zahm, J.A, Rosen, M.K.
Deposit date:2013-08-08
Release date:2013-10-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.748 Å)
Cite:The Bacterial Effector VopL Organizes Actin into Filament-like Structures.
Cell(Cambridge,Mass.), 155, 2013
2FXU
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BU of 2fxu by Molmil
X-ray Structure of Bistramide A- Actin Complex at 1.35 A resolution.
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Rizvi, S.A, Tereshko, V, Kossiakoff, A.A, Kozmin, S.A.
Deposit date:2006-02-06
Release date:2006-03-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure of bistramide a-actin complex at a 1.35 A resolution
J.Am.Chem.Soc., 128, 2006
2GWK
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BU of 2gwk by Molmil
SpvB ADP-ribosylated actin: orthorhombic crystal form
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Stebbins, C.E, Margarit, S.M.
Deposit date:2006-05-04
Release date:2006-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A steric antagonism of actin polymerization by a salmonella virulence protein.
Structure, 14, 2006
2GWJ
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BU of 2gwj by Molmil
SpvB ADP-ribosylated actin: hexagonal crystal form
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Stebbins, C.E, Margarit, S.M.
Deposit date:2006-05-04
Release date:2006-08-29
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A steric antagonism of actin polymerization by a salmonella virulence protein.
Structure, 14, 2006
2HF4
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BU of 2hf4 by Molmil
Crystal structure of Monomeric Actin in its ATP-bound state
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION
Authors:Rould, M.A, Wan, Q, Joel, P.B, Lowey, S, Trybus, K.M.
Deposit date:2006-06-22
Release date:2006-08-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structures of Expressed Non-polymerizable Monomeric Actin in the ADP and ATP States.
J.Biol.Chem., 281, 2006
2HF3
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BU of 2hf3 by Molmil
Crystal structure of monomeric Actin in the ADP bound state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin-5C, CALCIUM ION
Authors:Rould, M.A, Wan, Q, Joel, P.B, Lowey, S, Trybus, K.M.
Deposit date:2006-06-22
Release date:2006-08-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structures of Expressed Non-polymerizable Monomeric Actin in the ADP and ATP States.
J.Biol.Chem., 281, 2006
2HMP
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BU of 2hmp by Molmil
Uncomplexed actin cleaved with protease ECP32
Descriptor: 1,2-ETHANEDIOL, 2,2',2''-NITRILOTRIETHANOL, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Klenchin, V.A, Khaitlina, S.Y, Rayment, I.
Deposit date:2006-07-11
Release date:2006-09-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Crystal structure of polymerization-competent actin
J.Mol.Biol., 362, 2006
6W7V
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BU of 6w7v by Molmil
Structure of rabbit actin in complex with truncated analog of Mycalolide B
Descriptor: (1E,3R,4R,5S,6R,9S,10S,12S)-12-[(4-aminobutanoyl)oxy]-1-[ethyl(formyl)amino]-4,10-dimethoxy-3,5,9,13-tetramethyltetradec-1-en-6-yl (2R)-oxolane-2-carboxylate, 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Allingham, J.S, Deng, X, Trofimova, D.
Deposit date:2020-03-19
Release date:2020-10-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Truncated Actin-Targeting Macrolide Derivative Blocks Cancer Cell Motility and Invasion of Extracellular Matrix.
J.Am.Chem.Soc., 143, 2021
6WVT
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BU of 6wvt by Molmil
Structural basis of alphaE-catenin - F-actin catch bond behavior
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Xu, X.P, Pokutta, S, Torres, M, Swift, M.F, Hanein, D, Volkmann, N, Weis, W.I.
Deposit date:2020-05-06
Release date:2020-10-07
Method:ELECTRON MICROSCOPY (3.56 Å)
Cite:Structural basis of alpha E-catenin-F-actin catch bond behavior.
Elife, 9, 2020
7K21
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BU of 7k21 by Molmil
Cryo-EM structure of pyrene-labeled ADP-Pi-actin filaments
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Chou, S.Z, Pollard, T.D.
Deposit date:2020-09-08
Release date:2020-11-04
Last modified:2020-12-02
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-electron microscopy structures of pyrene-labeled ADP-P i - and ADP-actin filaments.
Nat Commun, 11, 2020
7K20
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BU of 7k20 by Molmil
Cryo-EM structure of pyrene-labeled ADP-actin filaments
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Chou, S.Z, Pollard, T.D.
Deposit date:2020-09-08
Release date:2020-11-04
Last modified:2020-12-02
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-electron microscopy structures of pyrene-labeled ADP-P i - and ADP-actin filaments.
Nat Commun, 11, 2020
3MN7
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BU of 3mn7 by Molmil
Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION, ...
Authors:Ducka, A.M, Sitar, T, Popowicz, G.M, Huber, R, Holak, T.A.
Deposit date:2010-04-21
Release date:2010-05-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of actin-bound Wiskott-Aldrich syndrome protein homology 2 (WH2) domains of Spire and the implication for filament nucleation.
Proc.Natl.Acad.Sci.USA, 107, 2010
3M6G
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BU of 3m6g by Molmil
Crystal structure of actin in complex with lobophorolide
Descriptor: (1S,3S,4S,5S,7R,8S,9R,12E,14E,16R,17R,19R)-16-hydroxy-9-{(1S,2S,3S)-2-hydroxy-5-[(2S,4R,6S)-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl]-1,3-dimethylpentyl}-3,5,7,17-tetramethoxy-8,14-dimethyl-11H-spiro[10,23-dioxabicyclo[17.3.1]tricosa-12,14,20-triene-4,2'-oxiran]-11-one, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Allingham, J.S.
Deposit date:2010-03-15
Release date:2010-09-08
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Two molecules of lobophorolide cooperate to stabilize an actin dimer using both their "ring" and "tail" region.
Chem.Biol., 17, 2010
3MN6
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BU of 3mn6 by Molmil
Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION, ...
Authors:Ducka, A.M, Sitar, T, Popowicz, G.M, Huber, R, Holak, T.A.
Deposit date:2010-04-21
Release date:2010-06-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of actin-bound Wiskott-Aldrich syndrome protein homology 2 (WH2) domains of Spire and the implication for filament nucleation.
Proc.Natl.Acad.Sci.USA, 107, 2010

217705

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