1CDQ
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STRUCTURE OF A SOLUBLE, GLYCOSYLATED FORM OF THE HUMAN COMPLEMENT REGULATORY PROTEIN CD59
Descriptor:CD59
Authors:Fletcher, C.M., Harrison, R.A., Lachmann, P.J., Neuhaus, D.
Deposit date:1994-06-01
Release date:1994-09-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of a soluble, glycosylated form of the human complement regulatory protein CD59.
Structure, 2, 1994
1CDR
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STRUCTURE OF A SOLUBLE, GLYCOSYLATED FORM OF THE HUMAN COMPLEMENT REGULATORY PROTEIN CD59
Descriptor:CD59, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE
Authors:Fletcher, C.M., Harrison, R.A., Lachmann, P.J., Neuhaus, D.
Deposit date:1994-06-01
Release date:1994-09-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of a soluble, glycosylated form of the human complement regulatory protein CD59.
Structure, 2, 1994
1CDS
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STRUCTURE OF A SOLUBLE, GLYCOSYLATED FORM OF THE HUMAN COMPLEMENT REGULATORY PROTEIN CD59
Descriptor:CD59, N-ACETYL-D-GLUCOSAMINE
Authors:Fletcher, C.M., Harrison, R.A., Lachmann, P.J., Neuhaus, D.
Deposit date:1994-06-01
Release date:1994-09-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of a soluble, glycosylated form of the human complement regulatory protein CD59.
Structure, 2, 1994
1ERG
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THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE EXTRACELLULAR REGION OF THE COMPLEMENT REGULATORY PROTEIN, CD59, A NEW CELL SURFACE PROTEIN DOMAIN RELATED TO NEUROTOXINS
Descriptor:CD59
Authors:Kieffer, B., Driscoll, P.C., Campbell, I.D., Willis, A.C., Van Der Merwe, P.A., Davis, S.J.
Deposit date:1993-12-13
Release date:1994-04-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of the extracellular region of the complement regulatory protein CD59, a new cell-surface protein domain related to snake venom neurotoxins.
Biochemistry, 33, 1994
1ERH
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THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE EXTRACELLULAR REGION OF THE COMPLEMENT REGULATORY PROTEIN, CD59, A NEW CELL SURFACE PROTEIN DOMAIN RELATED TO NEUROTOXINS
Descriptor:CD59
Authors:Kieffer, B., Driscoll, P.C., Campbell, I.D., Willis, A.C., Van Der Merwe, P.A., Davis, S.J.
Deposit date:1993-12-13
Release date:1994-04-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of the extracellular region of the complement regulatory protein CD59, a new cell-surface protein domain related to snake venom neurotoxins.
Biochemistry, 33, 1994
1YWH
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CRYSTAL STRUCTURE OF UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR
Descriptor:Urokinase plasminogen activator surface receptor, antagonist peptide, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Llinas, P., Le Du, M.H., Gardsvoll, H., Dano, K., Ploug, M., Gilquin, B., Stura, E.A., Menez, A.
Deposit date:2005-02-18
Release date:2005-05-10
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the human urokinase plasminogen activator receptor bound to an antagonist peptide
EMBO J., 24, 2005
2J8B
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HIGH RESOLUTION STRUCTURE OF HUMAN CD59
Descriptor:CD59 GLYCOPROTEIN
Authors:Leath, K.J., Johnson, S., Roversi, P., Morgan, B.P., Smith, R.A.G., Lea, S.M.
Deposit date:2006-10-24
Release date:2007-08-07
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:High-Resolution Structures of Bacterially Expressed Soluble Human Cd59.
Acta Crystallogr.,Sect.F, 63, 2007
2MUO
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STRUCTURE OF THE TRANS-(TYR39-PRO40) FORM OF THE HUMAN SECRETED LY-6/UPAR RELATED PROTEIN-1 (SLURP-1)
Descriptor:Secreted Ly-6/uPAR-related protein 1
Authors:Paramonov, A.S., Shenkarev, Z.O., Lyukmanova, E.N., Arseniev, A.S.
Deposit date:2014-09-15
Release date:2015-12-09
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Structural and Functional Properties of Human Secreted Ly-6/uPAR Related Protein-1 (SLURP-1) Imply a Non-Canonical Mode of Interaction with 7 nAChR
To be Published
2MUP
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STRUCTURE OF THE CIS-(TYR39-PRO40) FORM OF THE HUMAN SECRETED LY-6/UPAR RELATED PROTEIN-1 (SLURP-1)
Descriptor:Secreted Ly-6/uPAR-related protein 1
Authors:Paramonov, A.S., Shenkarev, Z.O., Lyukmanova, E.N., Arseniev, A.S.
Deposit date:2014-09-15
Release date:2015-12-09
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Structural and Functional Properties of Human Secreted Ly-6/uPAR Related Protein-1 (SLURP-1) Imply a Non-Canonical Mode of Interaction with 7 nAChR
To be Published
2OFS
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CRYSTAL STRUCTURE OF HUMAN CD59
Descriptor:CD59 glycoprotein
Authors:Davies, C.
Deposit date:2007-01-04
Release date:2007-05-29
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Crystal structure of CD59: implications for molecular recognition of the complement proteins C8 and C9 in the membrane-attack complex.
Acta Crystallogr.,Sect.D, 63, 2007
2UWR
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HIGH RESOLUTION STRUCTURE OF HUMAN CD59
Descriptor:CD59 GLYCOPROTEIN
Authors:Leath, K.J., Johnson, S., Roversi, P., Morgan, B.P., Smith, R.A.G., Lea, S.M.
Deposit date:2007-03-23
Release date:2007-08-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:High-Resolution Structures of Bacterially Expressed Soluble Human Cd59.
Acta Crystallogr.,Sect.F, 63, 2007
2UX2
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HIGH RESOLUTION STRUCTURE OF HUMAN CD59
Descriptor:CD59 GLYCOPROTEIN
Authors:Leath, K.J., Johnson, S., Roversi, P., Morgan, B.P., Smith, R.A.G., Lea, S.M.
Deposit date:2007-03-26
Release date:2007-08-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:High-Resolution Structures of Bacterially Expressed Soluble Human Cd59.
Acta Crystallogr.,Sect.F, 63, 2007
3U74
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CRYSTAL STRUCTURE OF STABILIZED HUMAN UPAR MUTANT
Descriptor:Urokinase plasminogen activator surface receptor, N-ACETYL-D-GLUCOSAMINE
Authors:Huang, M.D., Xu, X., Yuan, C.
Deposit date:2011-10-13
Release date:2012-04-18
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Crystal structure of the urokinase receptor in a ligand-free form.
J.Mol.Biol., 416, 2012
4QTI
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CRYSTAL STRUCTURE OF HUMAN UPAR IN COMPLEX WITH ANTI-UPAR FAB 8B12
Descriptor:anti-uPAR antibody, heavy chain, light chain, ...
Authors:Zhao, B., Yuan, C., Luo, Z., Huang, M.
Deposit date:2014-07-08
Release date:2015-02-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Stabilizing a flexible interdomain hinge region harboring the SMB binding site drives uPAR into its closed conformation
J.Mol.Biol., 2015
2FD6
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STRUCTURE OF HUMAN UROKINASE PLASMINOGEN ACTIVATOR IN COMPLEX WITH UROKINASE RECEPTOR AND AN ANTI-UPAR ANTIBODY AT 1.9 A
Descriptor:Urokinase-type plasminogen activator, L chain of Fab of ATN-615 anti-uPAR antibody, H chain of Fab of ATN-615 anti-uPAR antibody, ...
Authors:Huang, M., Huai, Q., Li, Y.
Deposit date:2005-12-13
Release date:2006-02-21
Last modified:2012-07-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of human urokinase plasminogen activator in complex with its receptor
Science, 311, 2006
2I9B
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CRYSTAL STRUCTURE OF ATF-UROKINASE RECEPTOR COMPLEX
Descriptor:Urokinase-type plasminogen activator, Urokinase plasminogen activator surface receptor, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Lubkowski, J., Barinka, C.
Deposit date:2006-09-05
Release date:2007-01-02
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of interaction between urokinase-type plasminogen activator and its receptor.
J.Mol.Biol., 363, 2006
3BT1
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STRUCTURE OF UROKINASE RECEPTOR, UROKINASE AND VITRONECTIN COMPLEX
Descriptor:Urokinase-type plasminogen activator, Vitronectin, Urokinase plasminogen activator surface receptor, ...
Authors:Huang, M.
Deposit date:2007-12-27
Release date:2008-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes
Nat.Struct.Mol.Biol., 15, 2008
3BT2
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STRUCTURE OF UROKINASE RECEPTOR, UROKINASE AND VITRONECTIN COMPLEX
Descriptor:Urokinase-type plasminogen activator, Vitronectin, anti-uPAR antibody, ...
Authors:Huang, M.
Deposit date:2007-12-27
Release date:2008-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes
Nat.Struct.Mol.Biol., 15, 2008
3LAQ
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STRUCTURE-BASED ENGINEERING OF SPECIES SELECTIVITY IN THE UPA-UPAR INTERACTION
Descriptor:Urokinase-type plasminogen activator, Urokinase plasminogen activator surface receptor, N-ACETYL-D-GLUCOSAMINE
Authors:Huang, M.
Deposit date:2010-01-06
Release date:2010-02-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure-based engineering of species selectivity in the interaction between urokinase and its receptor: implication for preclinical cancer therapy.
J.Biol.Chem., 285, 2010
3U73
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CRYSTAL STRUCTURE OF STABILIZED HUMAN UPAR MUTANT IN COMPLEX WITH ATF
Descriptor:Urokinase plasminogen activator surface receptor, Urokinase-type plasminogen activator, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Huang, M.D., Xu, X., Yuan, C.
Deposit date:2011-10-13
Release date:2012-04-18
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Crystal structure of the urokinase receptor in a ligand-free form.
J.Mol.Biol., 416, 2012
4BIK
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STRUCTURE OF A DISULFIDE LOCKED MUTANT OF INTERMEDILYSIN WITH HUMAN CD59
Descriptor:INTERMEDILYSIN, CD59 GLYCOPROTEIN
Authors:Johnson, S., Brooks, N.J., Smith, R.A.G., Lea, S.M., Bubeck, D.
Deposit date:2013-04-10
Release date:2013-05-08
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (3.494 Å)
Cite:Structural Basis for Recognition of the Pore- Forming Toxin Intermedilysin by Human Complement Receptor Cd59
Cell Rep., 3, 2013
4K24
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STRUCTURE OF ANTI-UPAR FAB ATN-658 IN COMPLEX WITH UPAR
Descriptor:Urokinase-type plasminogen activator, Vitronectin, anti-uPAR antibody, ...
Authors:Huang, M.D., Xu, X., Yuan, C.
Deposit date:2013-04-08
Release date:2014-02-26
Last modified:2014-03-05
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Identification of a New Epitope in uPAR as a Target for the Cancer Therapeutic Monoclonal Antibody ATN-658, a Structural Homolog of the uPAR Binding Integrin CD11b ( alpha M)
Plos One, 9, 2014
5IMT
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TOXIN RECEPTOR COMPLEX
Descriptor:Intermedilysin, CD59 glycoprotein, TRIETHYLENE GLYCOL, ...
Authors:Morton, C.J., Lawrence, S.L., Feil, S.C., Parker, M.W.
Deposit date:2016-03-06
Release date:2016-08-24
Last modified:2016-09-14
Method:X-RAY DIFFRACTION (2.7001 Å)
Cite:Structural Basis for Receptor Recognition by the Human CD59-Responsive Cholesterol-Dependent Cytolysins.
Structure, 24, 2016
5IMY
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TRAPPED TOXIN
Descriptor:Vaginolysin, CD59 glycoprotein
Authors:Lawrence, S.L., Morton, C.J., Parker, M.W.
Deposit date:2016-03-07
Release date:2016-08-24
Last modified:2016-09-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis for Receptor Recognition by the Human CD59-Responsive Cholesterol-Dependent Cytolysins.
Structure, 24, 2016
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