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1S4U
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Crystal Structure analysis of the beta-propeller protein Ski8p
Descriptor: Antiviral protein SKI8
Authors:Cheng, Z, Song, H.
Deposit date:2004-01-18
Release date:2004-12-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of Ski8p, a WD-repeat protein with dual roles in mRNA metabolism and meiotic recombination
Protein Sci., 13, 2004
1SQ9
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Structure of Ski8p, a WD repeat protein involved in mRNA degradation and meiotic recombination
Descriptor: Antiviral protein SKI8, SULFATE ION
Authors:Madrona, A.Y, Wilson, D.K.
Deposit date:2004-03-18
Release date:2004-05-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structure of Ski8p, a protein regulating mRNA degradation: Implications for WD protein structure.
Protein Sci., 13, 2004
2BZE
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BU of 2bze by Molmil
NMR Structure of human RTF1 PLUS3 domain.
Descriptor: KIAA0252 PROTEIN
Authors:Truffault, V, Diercks, T, Ab, E, De Jong, R.N, Daniels, M.A, Kaptein, R, Folkers, G.E, Structural Proteomics in Europe (SPINE)
Deposit date:2005-08-16
Release date:2007-01-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure and DNA Binding of the Human Rtf1 Plus3 Domain.
Structure, 16, 2008
2DB9
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Solution structure of the plus-3 domain of human KIAA0252 protein
Descriptor: Paf1/RNA polymerase II complex component
Authors:Yoneyama, M, Kigawa, T, Tochio, N, Nameki, N, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-15
Release date:2006-06-15
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the plus-3 domain of human KIAA0252 protein
To be Published
3OW8
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Crystal Structure of the WD repeat-containing protein 61
Descriptor: UNKNOWN ATOM OR ION, WD repeat-containing protein 61
Authors:Tempel, W, Li, Z, Chao, X, Lam, R, Wernimont, A.K, He, H, Seitova, A, Pan, P.W, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2010-09-17
Release date:2010-09-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and function of WD40 domain proteins.
Protein Cell, 2, 2011
3V46
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Crystal Structure of Yeast Cdc73 C-Terminal Domain
Descriptor: Cell division control protein 73
Authors:Amrich, C.G, VanDemark, A.P.
Deposit date:2011-12-14
Release date:2012-02-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.549 Å)
Cite:Cdc73 subunit of Paf1 complex contains C-terminal Ras-like domain that promotes association of Paf1 complex with chromatin.
J.Biol.Chem., 287, 2012
4BUJ
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Crystal structure of the S. cerevisiae Ski2-3-8 complex
Descriptor: ANTIVIRAL HELICASE SKI2, ANTIVIRAL PROTEIN SKI8, SULFATE ION, ...
Authors:Halbach, F, Reichelt, P, Rode, M, Conti, E.
Deposit date:2013-06-20
Release date:2013-08-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:The Yeast Ski Complex: Crystal Structure and RNA Channeling to the Exosome Complex.
Cell(Cambridge,Mass.), 154, 2013
4DM4
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The conserved domain of yeast Cdc73
Descriptor: Cell division control protein 73
Authors:Chen, H, Shi, N, Gao, Y, Li, X, Niu, L, Teng, M.
Deposit date:2012-02-06
Release date:2012-08-22
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Crystallographic analysis of the conserved C-terminal domain of transcription factor Cdc73 from Saccharomyces cerevisiae reveals a GTPase-like fold.
Acta Crystallogr.,Sect.D, 68, 2012
4L1P
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Crystal Structure of Human Rtf1 Plus3 domain
Descriptor: GLYCEROL, RNA polymerase-associated protein RTF1 homolog
Authors:Wier, A.D, Heroux, A, VanDemark, A.P.
Deposit date:2013-06-03
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin.
Proc.Natl.Acad.Sci.USA, 110, 2013
4L1U
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Crystal Structure of Human Rtf1 Plus3 Domain in Complex with Spt5 CTR Phosphopeptide
Descriptor: GLYCEROL, RNA polymerase-associated protein RTF1 homolog, SULFATE ION, ...
Authors:Wier, A.D, Heroux, A, VanDemark, A.P.
Deposit date:2013-06-03
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.424 Å)
Cite:Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin.
Proc.Natl.Acad.Sci.USA, 110, 2013
4M6T
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Structure of human Paf1 and Leo1 complex
Descriptor: RNA polymerase II-associated factor 1 homolog, Linker, RNA polymerase-associated protein LEO1, ...
Authors:Shen, Y, Qin, X.
Deposit date:2013-08-11
Release date:2013-10-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.498 Å)
Cite:Structural insights into Paf1 complex assembly and histone binding
Nucleic Acids Res., 41, 2013
5E8B
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Crystal structure of the S. cerevisiae Rtf1 histone modification domain mutant R126A
Descriptor: BENZAMIDINE, RNA polymerase-associated protein RTF1, SODIUM ION
Authors:Wier, A.D, Heroux, A, VanDemark, A.P.
Deposit date:2015-10-14
Release date:2016-11-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:The Histone Modification Domain of Paf1 Complex Subunit Rtf1 Directly Stimulates H2B Ubiquitylation through an Interaction with Rad6.
Mol. Cell, 64, 2016
5EMX
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BU of 5emx by Molmil
Crystal structure of the S. cerevisiae Rtf1 histone modification domain mutant R124A R126A R128A
Descriptor: RNA polymerase-associated protein RTF1
Authors:Wier, A.D, Heroux, A, VanDemark, A.P.
Deposit date:2015-11-06
Release date:2016-10-26
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.399 Å)
Cite:The Histone Modification Domain of Paf1 Complex Subunit Rtf1 Directly Stimulates H2B Ubiquitylation through an Interaction with Rad6.
Mol.Cell, 64, 2016
5MC6
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BU of 5mc6 by Molmil
Cryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiae
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Schmidt, C, Kowalinski, E, Shanmuganathan, V, Defenouillere, Q, Braunger, K, Heuer, A, Pech, M, Namane, A, Berninghausen, O, Fromont-Racine, M, Jacquier, A, Conti, E, Becker, T, Beckmann, R.
Deposit date:2016-11-09
Release date:2017-01-18
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:The cryo-EM structure of a ribosome-Ski2-Ski3-Ski8 helicase complex.
Science, 354, 2016
5YDE
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BU of 5yde by Molmil
Crystal structure of a disease-related gene, hCDC73(1-111)
Descriptor: Parafibromin
Authors:Sun, W, Kuang, X.L, Liu, Y.P, Tian, L.F, Yan, X.X, Xu, W.Q.
Deposit date:2017-09-13
Release date:2017-12-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.023 Å)
Cite:Crystal structure of the N-terminal domain of human CDC73 and its implications for the hyperparathyroidism-jaw tumor (HPT-JT) syndrome
Sci Rep, 7, 2017
5YDF
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Crystal structure of a disease-related gene, hCDC73(1-100)
Descriptor: Parafibromin
Authors:Sun, W, Kuang, X.L, Liu, Y.P, Tian, L.F, Yan, X.X, Xu, W.Q.
Deposit date:2017-09-13
Release date:2017-12-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.399 Å)
Cite:Crystal structure of the N-terminal domain of human CDC73 and its implications for the hyperparathyroidism-jaw tumor (HPT-JT) syndrome
Sci Rep, 7, 2017
5ZYP
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BU of 5zyp by Molmil
Structure of the Yeast Ctr9/Paf1 complex
Descriptor: NICKEL (II) ION, RNA polymerase-associated protein CTR9,RNA polymerase II-associated protein 1
Authors:Xie, Y, Zheng, M, Zhou, H, Long, J.
Deposit date:2018-05-28
Release date:2018-09-26
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.532 Å)
Cite:Paf1 and Ctr9 subcomplex formation is essential for Paf1 complex assembly and functional regulation.
Nat Commun, 9, 2018
5ZYQ
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BU of 5zyq by Molmil
The Structure of Human PAF1/CTR9 complex
Descriptor: RNA polymerase-associated protein CTR9 homolog,RNA polymerase II-associated factor 1 homolog
Authors:Xie, Y, Zheng, M, Zhou, H, Long, J.
Deposit date:2018-05-28
Release date:2018-09-26
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.531 Å)
Cite:Paf1 and Ctr9 subcomplex formation is essential for Paf1 complex assembly and functional regulation.
Nat Commun, 9, 2018
6AF0
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BU of 6af0 by Molmil
Structure of Ctr9, Paf1 and Cdc73 ternary complex from Myceliophthora thermophila
Descriptor: Cdc73 protein, Ctr9 protein, Paf1 protein
Authors:Wang, Z, Deng, P, Zhou, Y.
Deposit date:2018-08-07
Release date:2018-09-19
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Transcriptional elongation factor Paf1 core complex adopts a spirally wrapped solenoidal topology.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6GME
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BU of 6gme by Molmil
Structure of H. sapiens SPT6 tandem SH2 domain
Descriptor: SPT6 tandem SH2 domain,Transcription elongation factor SPT6
Authors:Vos, S.M, Farnung, L, Cramer, P.
Deposit date:2018-05-25
Release date:2018-08-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Structure of activated transcription complex Pol II-DSIF-PAF-SPT6.
Nature, 560, 2018
6GMH
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BU of 6gmh by Molmil
Structure of activated transcription complex Pol II-DSIF-PAF-SPT6
Descriptor: CDC73, CTR9,RNA polymerase-associated protein CTR9 homolog,RNA polymerase-associated protein CTR9 homolog, DNA-directed RNA polymerase II subunit RPB9, ...
Authors:Vos, S.M, Farnung, L, Boehing, M, Linden, A, Wigge, C, Urlaub, H, Cramer, P.
Deposit date:2018-05-26
Release date:2018-08-22
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of activated transcription complex Pol II-DSIF-PAF-SPT6.
Nature, 560, 2018
6I84
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Structure of transcribing RNA polymerase II-nucleosome complex
Descriptor: DNA (158-MER), DNA (170-MER), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Farnung, L, Vos, S.M, Cramer, P.
Deposit date:2018-11-19
Release date:2019-01-02
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structure of transcribing RNA polymerase II-nucleosome complex.
Nat Commun, 9, 2018
6TED
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BU of 6ted by Molmil
Structure of complete, activated transcription complex Pol II-DSIF-PAF-SPT6 uncovers allosteric elongation activation by RTF1
Descriptor: DNA (37-MER), DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, ...
Authors:Vos, S.M, Farnung, L, Cramer, P.
Deposit date:2019-11-11
Release date:2020-07-22
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of complete Pol II-DSIF-PAF-SPT6 transcription complex reveals RTF1 allosteric activation.
Nat.Struct.Mol.Biol., 27, 2020
7APX
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BU of 7apx by Molmil
yeast THO-Sub2 complex
Descriptor: ATP-dependent RNA helicase SUB2, Protein TEX1, THO complex subunit 2,Tho2, ...
Authors:Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E.
Deposit date:2020-10-20
Release date:2020-12-02
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex.
Elife, 9, 2020
7AQO
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yeast THO-Sub2 complex dimer
Descriptor: BJ4_G0025130.mRNA.1.CDS.1, EM14S01-3B_G0007820.mRNA.1.CDS.1, TEX1 isoform 1, ...
Authors:Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E.
Deposit date:2020-10-22
Release date:2020-12-02
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex.
Elife, 9, 2020

 

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