5ZYP
| Structure of the Yeast Ctr9/Paf1 complex | Descriptor: | NICKEL (II) ION, RNA polymerase-associated protein CTR9,RNA polymerase II-associated protein 1 | Authors: | Xie, Y, Zheng, M, Zhou, H, Long, J. | Deposit date: | 2018-05-28 | Release date: | 2018-09-26 | Last modified: | 2019-05-22 | Method: | X-RAY DIFFRACTION (2.532 Å) | Cite: | Paf1 and Ctr9 subcomplex formation is essential for Paf1 complex assembly and functional regulation. Nat Commun, 9, 2018
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5ZYQ
| The Structure of Human PAF1/CTR9 complex | Descriptor: | RNA polymerase-associated protein CTR9 homolog,RNA polymerase II-associated factor 1 homolog | Authors: | Xie, Y, Zheng, M, Zhou, H, Long, J. | Deposit date: | 2018-05-28 | Release date: | 2018-09-26 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.531 Å) | Cite: | Paf1 and Ctr9 subcomplex formation is essential for Paf1 complex assembly and functional regulation. Nat Commun, 9, 2018
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7DKH
| Crystal structure of the Ctr9/Paf1/Cdc73/Rtf1 quaternary complex | Descriptor: | Cell division control protein 73, RNA polymerase II-associated protein 1, RNA polymerase-associated protein CTR9, ... | Authors: | Chen, F.L, Liu, B.B, Guo, L, Li, D.F, Zhou, H, Long, J.F. | Deposit date: | 2020-11-24 | Release date: | 2021-11-24 | Last modified: | 2022-01-05 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal Structure of the Core Module of the Yeast Paf1 Complex. J.Mol.Biol., 434, 2021
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4M6T
| Structure of human Paf1 and Leo1 complex | Descriptor: | RNA polymerase II-associated factor 1 homolog, Linker, RNA polymerase-associated protein LEO1, ... | Authors: | Shen, Y, Qin, X. | Deposit date: | 2013-08-11 | Release date: | 2013-10-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.498 Å) | Cite: | Structural insights into Paf1 complex assembly and histone binding Nucleic Acids Res., 41, 2013
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6AF0
| Structure of Ctr9, Paf1 and Cdc73 ternary complex from Myceliophthora thermophila | Descriptor: | Cdc73 protein, Ctr9 protein, Paf1 protein | Authors: | Wang, Z, Deng, P, Zhou, Y. | Deposit date: | 2018-08-07 | Release date: | 2018-09-19 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | Transcriptional elongation factor Paf1 core complex adopts a spirally wrapped solenoidal topology. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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8J8Q
| Structure of the four-component Paf1 complex from Saccharomyces eubayanus | Descriptor: | CDC73-like protein, CTR9-like protein, PAF1-like protein, ... | Authors: | Wang, Z, Qin, Y, Zhou, Y, Cao, Y. | Deposit date: | 2023-05-02 | Release date: | 2023-05-24 | Last modified: | 2023-06-14 | Method: | X-RAY DIFFRACTION (3.11 Å) | Cite: | Structural Basis of the Transcriptional Elongation Factor Paf1 Core Complex from Saccharomyces eubayanus . Int J Mol Sci, 24, 2023
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8J8P
| Structure of the four-component Paf1 complex from Saccharomyces eubayanus | Descriptor: | CDC73-like protein, CTR9-like protein, PAF1-like protein, ... | Authors: | Wang, Z, Qin, Y, Zhou, Y, Cao, Y. | Deposit date: | 2023-05-02 | Release date: | 2023-05-24 | Last modified: | 2023-06-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Basis of the Transcriptional Elongation Factor Paf1 Core Complex from Saccharomyces eubayanus . Int J Mol Sci, 24, 2023
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3V46
| Crystal Structure of Yeast Cdc73 C-Terminal Domain | Descriptor: | Cell division control protein 73 | Authors: | Amrich, C.G, VanDemark, A.P. | Deposit date: | 2011-12-14 | Release date: | 2012-02-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.549 Å) | Cite: | Cdc73 subunit of Paf1 complex contains C-terminal Ras-like domain that promotes association of Paf1 complex with chromatin. J.Biol.Chem., 287, 2012
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6GMH
| Structure of activated transcription complex Pol II-DSIF-PAF-SPT6 | Descriptor: | CDC73, CTR9,RNA polymerase-associated protein CTR9 homolog,RNA polymerase-associated protein CTR9 homolog, DNA-directed RNA polymerase II subunit RPB9, ... | Authors: | Vos, S.M, Farnung, L, Boehing, M, Linden, A, Wigge, C, Urlaub, H, Cramer, P. | Deposit date: | 2018-05-26 | Release date: | 2018-08-22 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure of activated transcription complex Pol II-DSIF-PAF-SPT6. Nature, 560, 2018
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5E8B
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5EMX
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6TED
| Structure of complete, activated transcription complex Pol II-DSIF-PAF-SPT6 uncovers allosteric elongation activation by RTF1 | Descriptor: | DNA (37-MER), DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, ... | Authors: | Vos, S.M, Farnung, L, Cramer, P. | Deposit date: | 2019-11-11 | Release date: | 2020-07-22 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure of complete Pol II-DSIF-PAF-SPT6 transcription complex reveals RTF1 allosteric activation. Nat.Struct.Mol.Biol., 27, 2020
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4L1P
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4L1U
| Crystal Structure of Human Rtf1 Plus3 Domain in Complex with Spt5 CTR Phosphopeptide | Descriptor: | GLYCEROL, RNA polymerase-associated protein RTF1 homolog, SULFATE ION, ... | Authors: | Wier, A.D, Heroux, A, VanDemark, A.P. | Deposit date: | 2013-06-03 | Release date: | 2013-10-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.424 Å) | Cite: | Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin. Proc.Natl.Acad.Sci.USA, 110, 2013
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7OOP
| Pol II-CSB-CSA-DDB1-UVSSA-PAF-SPT6 (Structure 3) | Descriptor: | DNA damage-binding protein 1, DNA excision repair protein ERCC-6, DNA excision repair protein ERCC-8, ... | Authors: | Kokic, G, Cramer, P. | Deposit date: | 2021-05-28 | Release date: | 2021-10-06 | Last modified: | 2021-10-27 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of human transcription-DNA repair coupling. Nature, 598, 2021
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7OPD
| Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 5) | Descriptor: | Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ... | Authors: | Kokic, G, Cramer, P. | Deposit date: | 2021-05-31 | Release date: | 2021-10-06 | Last modified: | 2021-10-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of human transcription-DNA repair coupling. Nature, 598, 2021
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7OPC
| Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 4) | Descriptor: | Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ... | Authors: | Kokic, G, Cramer, P. | Deposit date: | 2021-05-31 | Release date: | 2021-10-13 | Last modified: | 2021-10-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of human transcription-DNA repair coupling. Nature, 598, 2021
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2DB9
| Solution structure of the plus-3 domain of human KIAA0252 protein | Descriptor: | Paf1/RNA polymerase II complex component | Authors: | Yoneyama, M, Kigawa, T, Tochio, N, Nameki, N, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-12-15 | Release date: | 2006-06-15 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Solution structure of the plus-3 domain of human KIAA0252 protein To be Published
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2BZE
| NMR Structure of human RTF1 PLUS3 domain. | Descriptor: | KIAA0252 PROTEIN | Authors: | Truffault, V, Diercks, T, Ab, E, De Jong, R.N, Daniels, M.A, Kaptein, R, Folkers, G.E, Structural Proteomics in Europe (SPINE) | Deposit date: | 2005-08-16 | Release date: | 2007-01-03 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structure and DNA Binding of the Human Rtf1 Plus3 Domain. Structure, 16, 2008
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4DM4
| The conserved domain of yeast Cdc73 | Descriptor: | Cell division control protein 73 | Authors: | Chen, H, Shi, N, Gao, Y, Li, X, Niu, L, Teng, M. | Deposit date: | 2012-02-06 | Release date: | 2012-08-22 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Crystallographic analysis of the conserved C-terminal domain of transcription factor Cdc73 from Saccharomyces cerevisiae reveals a GTPase-like fold. Acta Crystallogr.,Sect.D, 68, 2012
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7XSZ
| RNA polymerase II elongation complex transcribing a nucleosome (EC115) | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | Deposit date: | 2022-05-15 | Release date: | 2022-09-07 | Last modified: | 2022-10-12 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
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7XTD
| RNA polymerase II elongation complex transcribing a nucleosome (EC58oct) | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | Deposit date: | 2022-05-16 | Release date: | 2022-09-07 | Last modified: | 2022-10-19 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
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7XSX
| RNA polymerase II elongation complex transcribing a nucleosome (EC49) | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | Deposit date: | 2022-05-15 | Release date: | 2022-09-07 | Last modified: | 2022-10-12 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
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7XN7
| RNA polymerase II elongation complex containing Spt4/5, Elf1, Spt6, Spn1 and Paf1C | Descriptor: | Chromatin elongation factor SPT5, Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, ... | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | Deposit date: | 2022-04-28 | Release date: | 2022-09-07 | Last modified: | 2022-10-12 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
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7XSE
| RNA polymerase II elongation complex transcribing a nucleosome (EC42) | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | Deposit date: | 2022-05-13 | Release date: | 2022-09-07 | Last modified: | 2022-10-12 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
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