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7NH7
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BU of 7nh7 by Molmil
OC43 coronavirus methyltransferase
Descriptor: Replicase polyprotein 1a, Replicase polyprotein 1ab, SINEFUNGIN, ...
Authors:Dostalik, P, Krafcikova, P, Boura, E.
Deposit date:2021-02-10
Release date:2021-06-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:OC43 coronavirus methyltransferase
To Be Published
7PNQ
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BU of 7pnq by Molmil
Human coronavirus OC43 spike glycoprotein ectodomain in complex with the 43E6 antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 43E6 antibody heavy chain, 43E6 antibody light chain, ...
Authors:Hurdiss, D.L.
Deposit date:2021-09-07
Release date:2022-04-20
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Antigenic structure of the human coronavirus OC43 spike reveals exposed and occluded neutralizing epitopes.
Nat Commun, 13, 2022
7PNM
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BU of 7pnm by Molmil
Human coronavirus OC43 spike glycoprotein ectodomain in complex with the 46C12 antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 46C12 antibody heavy chain, ...
Authors:Hurdiss, D.L.
Deposit date:2021-09-07
Release date:2022-04-20
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Antigenic structure of the human coronavirus OC43 spike reveals exposed and occluded neutralizing epitopes.
Nat Commun, 13, 2022
7PO5
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BU of 7po5 by Molmil
Human coronavirus OC43 spike glycoprotein ectodomain in complex with the 47C9 antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 47C9 antibody heavy chain, 47C9 antibody light chain, ...
Authors:Hurdiss, D.L.
Deposit date:2021-09-08
Release date:2022-04-20
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Antigenic structure of the human coronavirus OC43 spike reveals exposed and occluded neutralizing epitopes.
Nat Commun, 13, 2022
4J3K
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BU of 4j3k by Molmil
Structure of the N-terminal domian of human coronavirus OC43 nucleocapsid protein
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Nucleoprotein
Authors:Chen, I.J, Lin, S.Y, Hou, M.H.
Deposit date:2013-02-05
Release date:2013-05-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure-based exploration of the important role of Arg106 in the RNA-binding domain of human coronavirus OC43 nucleocapsid protein
Biochim.Biophys.Acta, 1834, 2013
8QO2
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BU of 8qo2 by Molmil
Conserved Structures and Dynamics in 5-Proximal Regions of Betacoronavirus RNA Genomes
Descriptor: OC43-CoV-SL5
Authors:Moura, T.R, Purta, E, Bernat, A, Baulin, E, Mukherjee, S, Bujnicki, J.M.
Deposit date:2023-09-27
Release date:2024-03-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:Conserved structures and dynamics in 5'-proximal regions of Betacoronavirus RNA genomes.
Nucleic Acids Res., 2024
4LM7
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BU of 4lm7 by Molmil
Crystal structure of HCoV-OC43 N-NTD complexed with UMP
Descriptor: Nucleoprotein, URIDINE-5'-MONOPHOSPHATE
Authors:Lin, S.Y, Liu, C.L, Hou, M.H.
Deposit date:2013-07-10
Release date:2014-05-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structural basis for the identification of the N-terminal domain of coronavirus nucleocapsid protein as an antiviral target
J.Med.Chem., 57, 2014
6QFY
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BU of 6qfy by Molmil
CRYSTAL STRUCTURE OF PORCINE HEMAGGLUTINATING ENCEPHALOMYELITIS VIRUS SPIKE PROTEIN LECTIN DOMAIN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Huizinga, E.G, Bakkers, M, Lang, Y.
Deposit date:2019-01-10
Release date:2019-02-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Human coronaviruses OC43 and HKU1 bind to 9-O-acetylated sialic acids via a conserved receptor-binding site in spike protein domain A.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
5N11
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BU of 5n11 by Molmil
Crystal structure of Human beta1-coronavirus OC43 NL/A/2005 Hemagglutinin-Esterase
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, ...
Authors:Bakkers, M.J.G, Feitsma, L.J, de Groot, R.J, Huizinga, E.G.
Deposit date:2017-02-04
Release date:2017-03-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Betacoronavirus Adaptation to Humans Involved Progressive Loss of Hemagglutinin-Esterase Lectin Activity.
Cell Host Microbe, 21, 2017
6OHW
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BU of 6ohw by Molmil
Structural basis for human coronavirus attachment to sialic acid receptors. Apo-HCoV-OC43 S
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike surface glycoprotein, ...
Authors:Tortorici, M.A, Walls, A.C, Lang, Y, Wang, C, Li, Z, Koerhuis, D, Boons, G.J, Bosch, B.J, Rey, F.A, de Groot, R, Veesler, D.
Deposit date:2019-04-07
Release date:2019-06-05
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for human coronavirus attachment to sialic acid receptors.
Nat.Struct.Mol.Biol., 26, 2019
8HQV
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BU of 8hqv by Molmil
The complex structure of COPI cargo sorting module with HCoV-OC43 Spike KTSHxx sorting motif
Descriptor: Coatomer subunit beta', HCoV-OC43 Spike KTSHxx sorting motif
Authors:Ma, W.F, Nan, Y.N, Yang, M.R, Li, Y.Q.
Deposit date:2022-12-14
Release date:2023-12-20
Method:X-RAY DIFFRACTION (1.398 Å)
Cite:Tighter ER retention of SARS-CoV-2 Omicron spike caused by a constellation of folding disruptive mutations
To Be Published
8HR0
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BU of 8hr0 by Molmil
The complex structure of COPII coat with HCoV-OC43 DD sorting motif
Descriptor: HCoV-OC43, Protein transport protein Sec23A, Protein transport protein Sec24A, ...
Authors:Ma, W.F, Nan, Y.N, Yang, M.R, Li, Y.Q.
Deposit date:2022-12-14
Release date:2023-12-20
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:Tighter ER retention of SARS-CoV-2 Omicron spike caused by a constellation of folding disruptive mutations
To Be Published
4KXJ
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BU of 4kxj by Molmil
Crystal structure of HCoV-OC43 N-NTD complexed with PJ34
Descriptor: Nucleoprotein, N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE
Authors:Lin, S.Y, Hou, M.H.
Deposit date:2013-05-27
Release date:2014-05-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis for the identification of the N-terminal domain of coronavirus nucleocapsid protein as an antiviral target
J.Med.Chem., 57, 2014
4LM9
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BU of 4lm9 by Molmil
Crystal structure of HCoV-OC43 N-NTD complexed with GMP
Descriptor: GUANOSINE-5'-MONOPHOSPHATE, Nucleoprotein
Authors:Lin, S.Y, Liu, C.L, Hou, M.H.
Deposit date:2013-07-10
Release date:2014-05-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Structural basis for the identification of the N-terminal domain of coronavirus nucleocapsid protein as an antiviral target
J.Med.Chem., 57, 2014
4LMC
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BU of 4lmc by Molmil
Crystal structure of HCoV-OC43 N-NTD complexed with CMP
Descriptor: CYTIDINE-5'-MONOPHOSPHATE, Nucleoprotein
Authors:Lin, S.Y, Liu, C.L, Hou, M.H.
Deposit date:2013-07-10
Release date:2014-05-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.742 Å)
Cite:Structural basis for the identification of the N-terminal domain of coronavirus nucleocapsid protein as an antiviral target
J.Med.Chem., 57, 2014
4LI4
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BU of 4li4 by Molmil
Crystal structure of HCoV-OC43 N-NTD complexed with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, Nucleoprotein
Authors:Lin, S.Y, Liu, C.L, Hou, M.H.
Deposit date:2013-07-02
Release date:2014-05-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Structural basis for the identification of the N-terminal domain of coronavirus nucleocapsid protein as an antiviral target
J.Med.Chem., 57, 2014
8ELG
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BU of 8elg by Molmil
Crystal Structure of HLA-B*15:01 in complex with spike derived peptide NQKLIANAF from OC43 virus
Descriptor: ACETATE ION, Beta-2-microglobulin, NQK-OC43 peptide, ...
Authors:Murdolo, L.D, Gras, S.
Deposit date:2022-09-24
Release date:2023-06-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection.
Nature, 620, 2023
7SBX
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BU of 7sbx by Molmil
Structure of OC43 spike in complex with polyclonal Fab6 (Donor 1051)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ...
Authors:Bangaru, S, Antanasijevic, A, Ward, A.
Deposit date:2021-09-26
Release date:2022-05-04
Last modified:2022-05-18
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural mapping of antibody landscapes to human betacoronavirus spike proteins.
Sci Adv, 8, 2022
7SBV
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BU of 7sbv by Molmil
Structure of OC43 spike in complex with polyclonal Fab4 (Donor 269)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ...
Authors:Bangaru, S, Antanasijevic, A, Ward, A.
Deposit date:2021-09-26
Release date:2022-05-04
Last modified:2022-05-18
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural mapping of antibody landscapes to human betacoronavirus spike proteins.
Sci Adv, 8, 2022
7SB3
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BU of 7sb3 by Molmil
Structure of OC43 spike in complex with polyclonal Fab1 (Donor 269)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ...
Authors:Ward, A, Bangaru, S, Antanasijevic, A.
Deposit date:2021-09-23
Release date:2022-05-04
Last modified:2022-05-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural mapping of antibody landscapes to human betacoronavirus spike proteins.
Sci Adv, 8, 2022
7SBW
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BU of 7sbw by Molmil
Structure of OC43 spike in complex with polyclonal Fab5 (Donor 1051)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ...
Authors:Bangaru, S, Antanasijevic, A, Ward, A.
Deposit date:2021-09-26
Release date:2022-05-04
Last modified:2022-05-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural mapping of antibody landscapes to human betacoronavirus spike proteins.
Sci Adv, 8, 2022
7SB4
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BU of 7sb4 by Molmil
Structure of OC43 spike in complex with polyclonal Fab2 (Donor 1412)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ...
Authors:Bangaru, S, Antanasijevic, A, Ward, A.
Deposit date:2021-09-23
Release date:2022-05-04
Last modified:2022-05-18
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Structural mapping of antibody landscapes to human betacoronavirus spike proteins.
Sci Adv, 8, 2022
7SB5
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BU of 7sb5 by Molmil
Structure of OC43 spike in complex with polyclonal Fab3 (Donor 1412)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ...
Authors:Bangaru, S, Antanasijevic, A, Ward, A.
Deposit date:2021-09-23
Release date:2022-05-04
Last modified:2022-05-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural mapping of antibody landscapes to human betacoronavirus spike proteins.
Sci Adv, 8, 2022
7SBY
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BU of 7sby by Molmil
Structure of OC43 spike in complex with polyclonal Fab7 (Donor 269)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ...
Authors:Bangaru, S, Antanasijevic, A, Ward, A.
Deposit date:2021-09-26
Release date:2022-05-04
Last modified:2022-05-18
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural mapping of antibody landscapes to human betacoronavirus spike proteins.
Sci Adv, 8, 2022
6NZK
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BU of 6nzk by Molmil
Structural basis for human coronavirus attachment to sialic acid receptors
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike surface glycoprotein, ...
Authors:Tortorici, M.A, Walls, A.C, Lang, Y, Wang, C, Li, Z, Koerhuis, D, Boons, G.J, Bosch, B.J, Rey, F.A, de Groot, R, Veesler, D.
Deposit date:2019-02-13
Release date:2019-06-05
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis for human coronavirus attachment to sialic acid receptors.
Nat.Struct.Mol.Biol., 26, 2019

 

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