PDB: 9 resultsInfo pagesStatus searchChemie searchBIRD

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7XPX	Cryo-EM structure of the histone methyltransferase SET8 bound to H4K20Ecx-nucleosome Descriptor: DNA (145-MER), Histone H2A, Histone H2B 1.1, ... Authors: Shi, L.X, Zhou, Z. Deposit date: 2022-05-06 Release date: 2022-06-01 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural basis of nucleosomal H4K20 methylation by methyltransferase SET8. Faseb J., 36, 2022
5UQD	DPY-21 in complex with Fe(II) and alpha-Ketoglutarate Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, 2-OXOGLUTARIC ACID, DumPY: shorter than wild-type, ... Authors: Brejc, K, Bian, Q, Uzawa, S, Wheeler, B.S, Anderson, E.C, King, D.S, Kranzusch, P.J, Preston, C.G, Meyer, B.J. Deposit date: 2017-02-07 Release date: 2017-09-13 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.798 Å) Cite: Dynamic Control of X Chromosome Conformation and Repression by a Histone H4K20 Demethylase. Cell, 171, 2017
5CPR	The novel SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity Descriptor: 6,7-dichloro-N-cyclopentyl-4-(pyridin-4-yl)phthalazin-1-amine, Histone-lysine N-methyltransferase SUV420H1, S-ADENOSYLMETHIONINE, ... Authors: Jakob, C.G, Upadhyay, A.K, Sun, C. Deposit date: 2015-07-21 Release date: 2017-01-25 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.22 Å) Cite: The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity. Nat. Chem. Biol., 13, 2017
5B3N	The crystal structure of anti-H4K20me1_scFv, 15F11 Descriptor: anti-H4K20me1_scFv Authors: Kujirai, T, Horikoshi, N, Kurumizaka, H. Deposit date: 2016-03-04 Release date: 2016-09-21 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.94 Å) Cite: A Genetically Encoded Probe for Live-Cell Imaging of H4K20 Monomethylation J.Mol.Biol., 428, 2016
5HQ2	Structural model of Set8 histone H4 Lys20 methyltransferase bound to nucleosome core particle Descriptor: DNA (149-MER), Guanine nucleotide exchange factor SRM1, Histone H2A, ... Authors: Tavarekere, G, McGinty, R.K, Tan, S. Deposit date: 2016-01-21 Release date: 2016-03-23 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (4.5 Å) Cite: Multivalent Interactions by the Set8 Histone Methyltransferase With Its Nucleosome Substrate. J.Mol.Biol., 428, 2016
3OB9	Structure of the human MSL3 chromo-barrel domain at 2.5 Angstrom resolution Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Male-specific lethal 3-like 1 (Drosophila), isoform CRA_c, ... Authors: Moore, S.A, Ferhatoglu, Y. Deposit date: 2010-08-06 Release date: 2010-10-13 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure of the human MSL3 chromo-barrel domain at 2.5 Angstrom resolution J.Biol.Chem., 2010
3OA6	Human MSL3 Chromodomain bound to DNA and H4K20me1 peptide Descriptor: DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*AP*G)-3'), DNA (5'-D(*GP*CP*TP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*A)-3'), H4 peptide monomethylated at lysine 20, ... Authors: Kim, D, Huang, P, Rastinejad, F, Khorasanizadeh, S. Deposit date: 2010-08-04 Release date: 2010-08-18 Last modified: 2017-11-08 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Corecognition of DNA and a methylated histone tail by the MSL3 chromodomain. Nat.Struct.Mol.Biol., 17, 2010
3F70	Crystal structure of L3MBTL2-H4K20me1 complex Descriptor: Lethal(3)malignant brain tumor-like 2 protein, N-METHYL-LYSINE Authors: Guo, Y, Qi, C, Allali-Hassani, A, Pan, P, Zhu, H, Dong, A, Mackenzie, F, Crombet, L, Loppnau, P, Kozieradzki, I, Vedadi, M, Edwards, A.M, Weigelt, J, Bountra, C, Arrowsmith, C.H, Botchkarev, A, Read, R, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2008-11-07 Release date: 2009-01-06 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2. Nucleic Acids Res., 37, 2009
3CEY	Crystal structure of L3MBTL2 Descriptor: Lethal(3)malignant brain tumor-like 2 protein Authors: Nady, N, Guo, Y, Pan, P, Allali-Hassani, A, Qi, C, Zhu, H, Dong, A, Mackenzie, F, Crombet, L, Loppnau, P, Kozieradzki, I, Vedadi, M, Edwards, A.M, Weigelt, J, Bountra, C, Arrowsmith, C.H, Bochkarev, A, Read, R, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2008-02-29 Release date: 2008-05-06 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2. Nucleic Acids Res., 37, 2009