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1PAQ
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CRYSTAL STRUCTURE OF THE CATALYTIC FRAGMENT OF EUKARYOTIC INITIATION FACTOR 2B EPSILON
分子名称: Translation initiation factor eIF-2B epsilon subunit
著者Boesen, T, Andersen, G.R, Pavitt, G.D.
登録日2003-05-14
公開日2004-02-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the catalytic fragment of translation initiation factor 2B and identification of a critically important catalytic residue.
J.Biol.Chem., 279, 2004
1TIG
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TRANSLATION INITIATION FACTOR 3 C-TERMINAL DOMAIN
分子名称: TRANSLATION INITIATION FACTOR 3
著者Biou, V, Shu, F, Ramakrishnan, V.
登録日1995-08-16
公開日1995-12-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray crystallography shows that translational initiation factor IF3 consists of two compact alpha/beta domains linked by an alpha-helix.
EMBO J., 14, 1995
2G2K
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NMR structure of an N-terminal fragment of the eukaryotic initiation factor 5 (eIF5)
分子名称: Eukaryotic translation initiation factor 5
著者Conte, M.R, Kelly, G, Babon, J, Sanfelice, D, Smerdon, S.J, Proud, C.G.
登録日2006-02-16
公開日2006-06-13
最終更新日2021-11-10
実験手法SOLUTION NMR
主引用文献Structure of the eukaryotic initiation factor (eIF) 5 reveals a fold common to several translation factors
Biochemistry, 45, 2006
2J76
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Solution structure and RNA interactions of the RNA recognition motif from eukaryotic translation initiation factor 4B
分子名称: EUKARYOTIC TRANSLATION INITIATION FACTOR 4B
著者Fleming, K, Ghuman, J, Yuan, X.M, Simpson, P, Szendroi, A, Matthews, S, Curry, S.
登録日2006-10-06
公開日2008-10-28
最終更新日2017-04-19
実験手法SOLUTION NMR
主引用文献Solution Structure and RNA Interactions of the RNA Recognition Motif from Eukaryotic Translation Initiation Factor 4B.
Biochemistry, 42, 2003
2D74
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Crystal structure of translation initiation factor aIF2betagamma heterodimer
分子名称: Translation initiation factor 2 beta subunit, Translation initiation factor 2 gamma subunit, ZINC ION
著者Sokabe, M, Yao, M, Sakai, N, Toya, S, Tanaka, I.
登録日2005-11-16
公開日2006-07-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of archaeal translational initiation factor 2 betagamma-GDP reveals significant conformational change of the beta-subunit and switch 1 region.
Proc.Natl.Acad.Sci.USA, 103, 2006
4B3X
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Bacterial translation initiation factor IF2 (1-363), apo form
分子名称: GLYCEROL, TRANSLATION INITIATION FACTOR IF-2
著者Simonetti, A, Urzhumtsev, A, Klaholz, B.P.
登録日2012-07-26
公開日2013-05-29
最終更新日2013-06-05
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of the Protein Core of Translation Initiation Factor 2 in Apo, GTP-Bound and Gdp-Bound Forms
Acta Crystallogr.,Sect.D, 69, 2013
4B47
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Bacterial translation initiation factor IF2 (1-363), complex with GDP at pH6.5
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, TRANSLATION INITIATION FACTOR IF-2
著者Simonetti, A, Urzhumtsev, A, Klaholz, B.P.
登録日2012-07-27
公開日2013-05-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Structure of the Protein Core of Translation Initiation Factor 2 in Apo, GTP-Bound and Gdp-Bound Forms
Acta Crystallogr.,Sect.D, 69, 2013
4B48
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Bacterial translation initiation factor IF2 (1-363), complex with GTP
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, TRANSLATION INITIATION FACTOR IF-2
著者Simonetti, A, Urzhumtsev, A, Klaholz, B.P.
登録日2012-07-27
公開日2013-05-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the Protein Core of Translation Initiation Factor 2 in Apo, GTP-Bound and Gdp-Bound Forms
Acta Crystallogr.,Sect.D, 69, 2013
1G7R
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X-RAY STRUCTURE OF TRANSLATION INITIATION FACTOR IF2/EIF5B
分子名称: TRANSLATION INITIATION FACTOR IF2/EIF5B
著者Roll-Mecak, A, Cao, C, Dever, T.E, Burley, S.K.
登録日2000-11-14
公開日2000-12-06
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献X-Ray structures of the universal translation initiation factor IF2/eIF5B: conformational changes on GDP and GTP binding.
Cell(Cambridge,Mass.), 103, 2000
3CW2
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Crystal structure of the intact archaeal translation initiation factor 2 from Sulfolobus solfataricus .
分子名称: Translation initiation factor 2 subunit alpha, Translation initiation factor 2 subunit beta, Translation initiation factor 2 subunit gamma
著者Stolboushkina, E.A, Nikonov, S.V, Nikulin, A.D, Blaesi, U, Manstein, D.J, Fedorov, R.V, Garber, M.B, Nikonov, O.S.
登録日2008-04-21
公開日2009-01-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the intact archaeal translation initiation factor 2 demonstrates very high conformational flexibility in the alpha- and beta-subunits.
J.Mol.Biol., 382, 2008
6C00
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Solution structure of translation initiation factor 1 from Clostridium difficile
分子名称: Translation initiation factor IF-1
著者Zhang, Y, Aguilar, F.
登録日2017-12-26
公開日2019-01-16
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献1H,13C and15N resonance assignments and structure prediction of translation initiation factor 1 from Clostridium difficile.
Biomol.Nmr Assign., 13, 2019
1TIF
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TRANSLATION INITIATION FACTOR 3 N-TERMINAL DOMAIN
分子名称: CHLORIDE ION, TRANSLATION INITIATION FACTOR 3, TRIMETHYL LEAD ION
著者Biou, V, Shu, F, Ramakrishnan, V.
登録日1995-08-16
公開日1995-12-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-ray crystallography shows that translational initiation factor IF3 consists of two compact alpha/beta domains linked by an alpha-helix.
EMBO J., 14, 1995
2N8N
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Solution structure of translation initiation factor
分子名称: Translation initiation factor IF-1
著者Kim, D, Lee, K, Lee, B.
登録日2015-10-21
公開日2016-10-26
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure and dynamics study of translation initiation factor 1 from Staphylococcus aureus suggests its RNA binding mode
Biochim.Biophys.Acta, 1865, 2017
1ND9
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Solution Structure of the N-terminal Subdomain of Translation Initiation Factor IF2
分子名称: Translation initiation factor IF-2
著者Laursen, B.S, Mortensen, K.K, Sperling-Petersen, H.U, Hoffman, D.W.
登録日2002-12-09
公開日2003-03-04
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献A conserved structural motif at the N terminus of bacterial translation initiation factor IF2
J.Biol.Chem., 278, 2003
1QDE
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CRYSTAL STRUCTURE OF THE ATPASE DOMAIN OF TRANSLATION INITIATION FACTOR 4A FROM SACCHAROMYCES CEREVISIAE-THE PROTOTYPE OF THE DEAD BOX PROTEIN FAMILY
分子名称: SULFATE ION, TRANSLATION INITIATION FACTOR 4A
著者Benz, J, Trachsel, H, Baumann, U.
登録日1999-05-20
公開日2000-05-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the ATPase domain of translation initiation factor 4A from Saccharomyces cerevisiae--the prototype of the DEAD box protein family.
Structure Fold.Des., 7, 1999
1Z9B
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Solution structure of the C1-subdomain of Bacillus stearothermophilus translation initiation factor IF2
分子名称: Translation initiation factor IF-2
著者Wienk, H, Tomaselli, S, Bernard, C, Spurio, R, Picone, D, Gualerzi, C.O, Boelens, R.
登録日2005-04-01
公開日2005-08-30
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Solution structure of the C1-subdomain of Bacillus stearothermophilus translation initiation factor IF2
Protein Sci., 14, 2005
4TQC
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The co-complex structure of the translation initiation factor eIF4E with the inhibitor 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G
分子名称: (2S)-3-(4-amino-3-nitrophenyl)-2-{2-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]hydrazinyl}propanoic acid, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Eukaryotic translation initiation factor 4E
著者Papadopoulos, E, Jenni, S, Wagner, G.
登録日2014-06-10
公開日2014-08-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G.
Proc.Natl.Acad.Sci.USA, 111, 2014
4TPW
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The co-complex structure of the translation initiation factor eIF4E with the inhibitor 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G
分子名称: (2E)-2-{2-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]hydrazinylidene}-3-(2-nitrophenyl)propanoic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, ...
著者Papadopoulos, E, Jenni, S, Wagner, G.
登録日2014-06-09
公開日2014-08-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G.
Proc.Natl.Acad.Sci.USA, 111, 2014
4TQB
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The co-complex structure of the translation initiation factor eIF4E with the inhibitor 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G
分子名称: (2E)-2-{2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]hydrazinylidene}-3-(2-nitrophenyl)propanoic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, ...
著者Papadopoulos, E, Jenni, S, Wagner, G.
登録日2014-06-10
公開日2014-08-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G.
Proc.Natl.Acad.Sci.USA, 111, 2014
1EIF
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EUKARYOTIC TRANSLATION INITIATION FACTOR 5A FROM METHANOCOCCUS JANNASCHII
分子名称: EUKARYOTIC TRANSLATION INITIATION FACTOR 5A
著者Kim, K.K, Hung, L.W, Yokota, H, Kim, R, Kim, S.H.
登録日1998-07-29
公開日1998-10-14
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of eukaryotic translation initiation factor 5A from Methanococcus jannaschii at 1.8 A resolution.
Proc.Natl.Acad.Sci.USA, 95, 1998
3TF2
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Crystal structure of the cap free human translation initiation factor eIF4E
分子名称: Eukaryotic translation initiation factor 4E, UNKNOWN ATOM OR ION
著者Siddiqui, N, Tempel, W, Nedyalkova, L, Wernimont, A.K, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Borden, K.L.B, Park, H, Structural Genomics Consortium (SGC)
登録日2011-08-15
公開日2011-08-31
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insights into the allosteric effects of 4EBP1 on the eukaryotic translation initiation factor eIF4E.
J.Mol.Biol., 415, 2012
3WJ9
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Crystal structure of the eukaryotic initiation factor
分子名称: Eukaryotic translation initiation factor 2A
著者Kashiwagi, K, Ito, T, Yokoyama, S.
登録日2013-10-07
公開日2014-03-12
最終更新日2022-08-24
実験手法X-RAY DIFFRACTION (2.506 Å)
主引用文献Crystal structure of the eukaryotic translation initiation factor 2A from Schizosaccharomyces pombe.
J Struct Funct Genomics, 15, 2014
1IPB
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CRYSTAL STRUCTURE OF EUKARYOTIC INITIATION FACTOR 4E COMPLEXED WITH 7-METHYL GPPPA
分子名称: EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE
著者Tomoo, K, Shen, X, Okabe, K, Nozoe, Y, Fukuhara, S, Morino, S, Ishida, T, Taniguchi, T, Hasegawa, H, Terashima, A, Sasaki, M, Katsuya, Y, Kitamura, K, Miyoshi, H, Ishikawa, M, Miura, K.
登録日2001-05-08
公開日2002-05-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of 7-methylguanosine 5'-triphosphate (m(7)GTP)- and P(1)-7-methylguanosine-P(3)-adenosine-5',5'-triphosphate (m(7)GpppA)-bound human full-length eukaryotic initiation factor 4E: biological importance of the C-terminal flexible region
BIOCHEM.J., 362, 2002
1IPC
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CRYSTAL STRUCTURE OF EUKARYOTIC INITIATION FACTOR 4E COMPLEXED WITH 7-METHYL GTP
分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E
著者Tomoo, K, Shen, X, Okabe, K, Nozoe, Y, Fukuhara, S, Morino, S, Ishida, T, Taniguchi, T, Hasegawa, H, Terashima, A, Sasaki, M, Katsuya, Y, Kitamura, K, Miyoshi, H, Ishikawa, M, Miura, K.
登録日2001-05-08
公開日2002-05-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of 7-methylguanosine 5'-triphosphate (m(7)GTP)- and P(1)-7-methylguanosine-P(3)-adenosine-5',5'-triphosphate (m(7)GpppA)-bound human full-length eukaryotic initiation factor 4E: biological importance of the C-terminal flexible region
BIOCHEM.J., 362, 2002
1KL9
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Crystal structure of the N-terminal segment of Human eukaryotic initiation factor 2alpha
分子名称: EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1, ZINC ION
著者Nonato, M.C, Widom, J, Clardy, J.
登録日2001-12-11
公開日2002-03-11
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the N-terminal segment of human eukaryotic translation initiation factor 2alpha
J.Biol.Chem., 277, 2002

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