Mine: Updated entries

6J5F
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COMPLEX STRUCTURE OF MAB 4.2-SCFV WITH TICK-BORNE ENCEPHALITIS VIRUS ENVELOPE PROTEIN DOMAIN III
Descriptor:Envelope protein, antibody heavy chain, antibody light chain
Authors:Yang, X., Qi, J., Peng, R., Dai, L., Gould, E.A., Tien, P., Gao, G.F.
Deposit date:2019-01-10
Release date:2019-02-06
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Molecular basis of a protective/neutralizing monoclonal antibody targeting envelope proteins of both tick-borne encephalitis virus and louping ill virus.
J. Virol., 2019
6J5G
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COMPLEX STRUCTURE OF MAB 4.2-SCFV WITH TICK-BORNE ENCEPHALITIS VIRUS ENVELOPE PROTEIN
Descriptor:Envelope protein E, antibody heavy chain, antibody light chain
Authors:Yang, X., Qi, J., Peng, R., Dai, L., Gould, E.A., Tien, P., Gao, G.F.
Deposit date:2019-01-10
Release date:2019-02-06
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (3.291 Å)
Cite:Molecular basis of a protective/neutralizing monoclonal antibody targeting envelope proteins of both tick-borne encephalitis virus and louping ill virus.
J. Virol., 2019
6J7C
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CRYSTAL STRUCTURE OF PROLINE RACEMASE-LIKE PROTEIN FROM THERMOCOCCUS LITORALIS IN COMPLEX WITH PROLINE
Descriptor:Proline racemase, PROLINE
Authors:Watanabe, Y., Watanabe, S., Itoh, Y., Watanabe, Y.
Deposit date:2019-01-17
Release date:2019-02-27
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of substrate-bound bifunctional proline racemase/hydroxyproline epimerase from a hyperthermophilic archaeon.
Biochem. Biophys. Res. Commun., 511, 2019
6JBZ
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STRUCTURAL ANALYSIS OF MOLYBDOPTERIN SYNTHASES FROM TWO MYCOBACTERIA PATHOGENS
Descriptor:Molybdenum cofactor biosynthesis protein E, MoaD/ThiS family protein, SULFATE ION
Authors:Wang, H.Y., Liu, X.
Deposit date:2019-01-27
Release date:2019-02-13
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.603 Å)
Cite:Structural analysis of molybdopterin synthases from two mycobacterial pathogens.
Biochem. Biophys. Res. Commun., 511, 2019
6JC0
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STRUCTURAL ANALYSIS OF MOLYBDOPTERIN SYNTHASES FROM TWO MYCOBACTERIA PATHOGENS
Descriptor:Putative molybdenum cofactor biosynthesis protein, Putative molybdenum cofactor biosynthesis protein D2 (MoaD2) / thiamine S
Authors:Liu, X., Wang, H.Y.
Deposit date:2019-01-27
Release date:2019-02-13
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural analysis of molybdopterin synthases from two mycobacterial pathogens.
Biochem. Biophys. Res. Commun., 511, 2019
6M8R
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CRYSTAL STRUCTURE OF THE KCTD16 BTB DOMAIN IN COMPLEX WITH GABAB2 PEPTIDE
Descriptor:BTB/POZ domain-containing protein KCTD16, Gamma-aminobutyric acid type B receptor subunit 2, MAGNESIUM ION
Authors:Zheng, S., Kruse, A.C.
Deposit date:2018-08-22
Release date:2019-02-27
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for KCTD-mediated rapid desensitization of GABABsignalling.
Nature, 567, 2019
6M8S
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CRYSTAL STRUCTURE OF THE KCTD12 H1 DOMAIN IN COMPLEX WITH GBETA1GAMMA2 SUBUNITS
Descriptor:Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, BTB/POZ domain-containing protein KCTD12
Authors:Zheng, S., Kruse, A.C.
Deposit date:2018-08-22
Release date:2019-02-27
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (3.71 Å)
Cite:Structural basis for KCTD-mediated rapid desensitization of GABABsignalling.
Nature, 567, 2019
6M9K
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CRYSTAL STRUCTURE OF LAMBDA EXONUCLEASE IN COMPLEX WITH THE RED BETA C-TERMINAL DOMAIN
Descriptor:Exonuclease, Recombination protein bet, SULFATE ION
Authors:Bell, C.E., Caldwell, B.J.
Deposit date:2018-08-23
Release date:2019-01-02
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the Red beta C-terminal domain in complex with lambda Exonuclease reveals an unexpected homology with lambda Orf and an interaction with Escherichia coli single stranded DNA binding protein.
Nucleic Acids Res., 47, 2019
6MAA
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WFIKKN2 FOLLISTATIN DOMAIN
Descriptor:WAP, Kazal, immunoglobulin, ...
Authors:McCoy, J.C., Walker, R.G., Thomas, T.B.
Deposit date:2018-08-27
Release date:2019-03-06
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (1.394 Å)
Cite:Crystal structure of the WFIKKN2 follistatin domain reveals insight into how it inhibits growth differentiation factor 8 (GDF8) and GDF11.
J. Biol. Chem., 2019
6MD7
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NON-RECEPTOR PROTEIN TYROSINE PHOSPHATASE SHP2 IN COMPLEX WITH ALLOSTERIC INHIBITOR PYRIMIDINONE 7
Descriptor:Tyrosine-protein phosphatase non-receptor type 11, 2-[4-(aminomethyl)-4-methylpiperidin-1-yl]-5-{[2-(trifluoromethyl)pyridin-3-yl]sulfanyl}pyrimidin-4(3H)-one, PHOSPHATE ION
Authors:Fodor, M., Stams, T.
Deposit date:2018-09-04
Release date:2019-02-13
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors.
J. Med. Chem., 62, 2019
6MD9
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NON-RECEPTOR PROTEIN TYROSINE PHOSPHATASE SHP2 IN COMPLEX WITH ALLOSTERIC INHIBITOR ISOXAZOLO-PYRIDINONE 3
Descriptor:Tyrosine-protein phosphatase non-receptor type 11, 3-(2-chlorophenyl)-6-{4-[(dimethylamino)methyl]phenyl}-5-methyl[1,2]oxazolo[4,5-c]pyridin-4(5H)-one, PHOSPHATE ION
Authors:Fodor, M., Stams, T.
Deposit date:2018-09-04
Release date:2019-02-13
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors.
J. Med. Chem., 62, 2019
6MDA
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NON-RECEPTOR PROTEIN TYROSINE PHOSPHATASE SHP2 IN COMPLEX WITH ALLOSTERIC INHIBITOR PYRAZOLO-PYRIDINE 4
Descriptor:Tyrosine-protein phosphatase non-receptor type 11, 3-(4-bromophenyl)-6-(4-methylphenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid, PHOSPHATE ION
Authors:Fodor, M., Stams, T.
Deposit date:2018-09-04
Release date:2019-02-13
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors.
J. Med. Chem., 62, 2019
6MDB
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NON-RECEPTOR PROTEIN TYROSINE PHOSPHATASE SHP2 IN COMPLEX WITH ALLOSTERIC INHIBITOR PYRAZOLO-PYRIMIDINONE 5
Descriptor:Tyrosine-protein phosphatase non-receptor type 11, 6-(4-amino-4-methylpiperidin-1-yl)-3-(2,3-dichlorophenyl)-5-methyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, PHOSPHATE ION
Authors:Fodor, M., Stams, T.
Deposit date:2018-09-04
Release date:2019-02-13
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors.
J. Med. Chem., 62, 2019
6MDC
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NON-RECEPTOR PROTEIN TYROSINE PHOSPHATASE SHP2 IN COMPLEX WITH ALLOSTERIC INHIBITOR PYRAZOLO-PYRIMIDINONE 1 SHP389
Descriptor:Tyrosine-protein phosphatase non-receptor type 11, 6-[(3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-3-[3-chloro-2-(cyclopropylamino)pyridin-4-yl]-5-methyl-2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, PHOSPHATE ION
Authors:Fodor, M., Stams, T.
Deposit date:2018-09-04
Release date:2019-02-13
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors.
J. Med. Chem., 62, 2019
6MDD
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NON-RECEPTOR PROTEIN TYROSINE PHOSPHATASE SHP2 IN COMPLEX WITH ALLOSTERIC INHIBITOR IMIDAZO-PYRIDINE 24
Descriptor:Tyrosine-protein phosphatase non-receptor type 11, 5-[(2,3-dichlorophenyl)sulfanyl]-3H-imidazo[4,5-b]pyridin-2-amine, PHOSPHATE ION
Authors:Fodor, M., Stams, T.
Deposit date:2018-09-04
Release date:2019-02-13
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors.
J. Med. Chem., 62, 2019
6MK3
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CRYSTALLOGRAPHIC SOLVENT MAPPING ANALYSIS OF DMSO BOUND TO APE1
Descriptor:DNA-(apurinic or apyrimidinic site) lyase, DIMETHYL SULFOXIDE, 1,2-ETHANEDIOL
Authors:Georgiadis, M.M., He, H., Chen, Q.
Deposit date:2018-09-24
Release date:2019-01-30
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (1.478 Å)
Cite:Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1.
J. Med. Chem., 62, 2019
6MKK
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CRYSTALLOGRAPHIC SOLVENT MAPPING ANALYSIS OF DMSO/MG BOUND TO APE1
Descriptor:DNA-(apurinic or apyrimidinic site) lyase, MAGNESIUM ION, DIMETHYL SULFOXIDE, ...
Authors:Georgiadis, M.M., He, H., Chen, Q.
Deposit date:2018-09-25
Release date:2019-01-30
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (1.442 Å)
Cite:Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1.
J. Med. Chem., 62, 2019
6MKM
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CRYSTALLOGRAPHIC SOLVENT MAPPING ANALYSIS OF DMSO/TRIS BOUND TO APE1
Descriptor:DNA-(apurinic or apyrimidinic site) lyase, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DIMETHYL SULFOXIDE, ...
Authors:Georgiadis, M.M., He, H., Chen, Q.
Deposit date:2018-09-25
Release date:2019-01-30
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (1.673 Å)
Cite:Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1.
J. Med. Chem., 62, 2019
6MKO
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CRYSTALLOGRAPHIC SOLVENT MAPPING ANALYSIS OF GLYCEROL BOUND TO APE1
Descriptor:DNA-(apurinic or apyrimidinic site) lyase, GLYCEROL
Authors:Georgiadis, M.M., He, H., Chen, Q.
Deposit date:2018-09-25
Release date:2019-01-30
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1.
J. Med. Chem., 62, 2019
6MUJ
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FORMYLGLYCINE GENERATING ENZYME BOUND TO COPPER
Descriptor:Formylglycine-generating enzyme, CALCIUM ION, COPPER (II) ION, ...
Authors:Lafrance-Vanasse, J., Appel, M.J., Tsai, C.-L., Bertozzi, C., Tainer, J.A.
Deposit date:2018-10-23
Release date:2019-02-27
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.249 Å)
Cite:Formylglycine-generating enzyme binds substrate directly at a mononuclear Cu(I) center to initiate O2activation.
Proc. Natl. Acad. Sci. U.S.A., 2019
6MVF
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CRYSTAL STRUCTURE OF FMN-BINDING BETA-GLUCURONIDASE FROM FACAELIBACTERIUM PRAUSNITZII L2-6
Descriptor:Beta-galactosidase/beta-glucuronidase, FLAVIN MONONUCLEOTIDE
Authors:Pellock, S.J., Redinbo, M.R.
Deposit date:2018-10-25
Release date:2019-01-30
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Discovery and Characterization of FMN-Binding beta-Glucuronidases in the Human Gut Microbiome.
J. Mol. Biol., 431, 2019
6MVG
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CRYSTAL STRUCTURE OF FMN-BINDING BETA-GLUCURONIDASE FROM RUMINOCOCCUS GNAVUS
Descriptor:beta-glucuronidase, FLAVIN MONONUCLEOTIDE, CALCIUM ION
Authors:Pellock, S.J., Redinbo, M.R.
Deposit date:2018-10-25
Release date:2019-01-30
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Discovery and Characterization of FMN-Binding beta-Glucuronidases in the Human Gut Microbiome.
J. Mol. Biol., 431, 2019
6MVH
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CRYSTAL STRUCTURE OF FMN-BINDING BETA-GLUCURONIDASE FROM ROSEBURIA HOMINIS
Descriptor:Beta-galactosidase, CALCIUM ION, FLAVIN MONONUCLEOTIDE
Authors:Pellock, S.J., Redinbo, M.R.
Deposit date:2018-10-25
Release date:2019-01-30
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Discovery and Characterization of FMN-Binding beta-Glucuronidases in the Human Gut Microbiome.
J. Mol. Biol., 431, 2019
6MXO
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STRUCTURE OF HPOLETA INCORPORATING DCTP OPPOSITE THE 3-PRIME PT(DACH)-GG
Descriptor:DNA polymerase eta, DNA (5'-D(*AP*CP*GP*GP*CP*TP*CP*AP*CP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*GP*TP*GP*AP*G)-3'), ...
Authors:Ouzon-Shubeita, H., Lee, S.
Deposit date:2018-10-31
Release date:2019-02-13
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural basis for the bypass of the major oxaliplatin-DNA adducts by human DNA polymerase eta.
Biochem. J., 476, 2019
6MZB
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CRYO-EM STRUCTURE OF PHOSPHODIESTERASE 6
Descriptor:Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta, Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, ...
Authors:Gulati, S., Palczewski, K.
Deposit date:2018-11-04
Release date:2019-03-06
Last modified:2019-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structure of phosphodiesterase 6 reveals insights into the allosteric regulation of type I phosphodiesterases.
Sci Adv, 5, 2019