2YD6
| Crystal structure of the N-terminal Ig1-2 module of Human Receptor Protein Tyrosine Phosphatase Delta | Descriptor: | CHLORIDE ION, CITRATE ANION, PTPRD PROTEIN | Authors: | Coles, C.H, Shen, Y, Tenney, A.P, Siebold, C, Sutton, G.C, Lu, W, Gallagher, J.T, Jones, E.Y, Flanagan, J.G, Aricescu, A.R. | Deposit date: | 2011-03-17 | Release date: | 2011-04-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Proteoglycan-Specific Molecular Switch for Rptp Sigma Clustering and Neuronal Extension. Science, 332, 2011
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2YD7
| Crystal structure of the N-terminal Ig1-2 module of Human Receptor Protein Tyrosine Phosphatase Delta | Descriptor: | PHOSPHATE ION, PTPRD PROTEIN | Authors: | Coles, C.H, Shen, Y, Tenney, A.P, Siebold, C, Sutton, G.C, Lu, W, Gallagher, J.T, Jones, E.Y, Flanagan, J.G, Aricescu, A.R. | Deposit date: | 2011-03-17 | Release date: | 2011-04-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Proteoglycan-Specific Molecular Switch for Rptp Sigma Clustering and Neuronal Extension. Science, 332, 2011
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7CEG
| Crystal structure of the complex between mouse PTP delta and neuroligin-3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform C of Receptor-type tyrosine-protein phosphatase delta, Neuroligin-3 | Authors: | Yamagata, A, Yoshida, T, Shiroshima, T, Maeda, A, Fukai, S. | Deposit date: | 2020-06-23 | Release date: | 2021-02-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.85 Å) | Cite: | Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice. Nat Commun, 12, 2021
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8S9P
| 1:1:1 agrin/LRP4/MuSK complex | Descriptor: | Agrin, Low-density lipoprotein receptor-related protein 4, Muscle, ... | Authors: | Xie, T, Xu, G.J, Liu, Y, Quade, B, Lin, W.C, Bai, X.C. | Deposit date: | 2023-03-29 | Release date: | 2023-05-17 | Last modified: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural insights into the assembly of the agrin/LRP4/MuSK signaling complex. Proc.Natl.Acad.Sci.USA, 120, 2023
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8G4L
| Cryo-EM structure of the human cardiac myosin filament | Descriptor: | Myosin light chain 3, Myosin regulatory light chain 2, ventricular/cardiac muscle isoform, ... | Authors: | Dutta, D, Nguyen, V, Padron, R, Craig, R. | Deposit date: | 2023-02-10 | Release date: | 2023-11-01 | Last modified: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (6.4 Å) | Cite: | Cryo-EM structure of the human cardiac myosin filament. Nature, 623, 2023
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7OL4
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7OL2
| Crystal structure of mouse contactin 1 immunoglobulin domains | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Contactin-1, ... | Authors: | Chataigner, L.M.P, Janssen, B.J.C. | Deposit date: | 2021-05-19 | Release date: | 2022-12-14 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.89 Å) | Cite: | Structural insights into the contactin 1 - neurofascin 155 adhesion complex. Nat Commun, 13, 2022
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6YGN
| Titin kinase and its flanking domains | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Titin | Authors: | Fleming, J.R, Franke, B, Bogomolovas, J, Mayans, O. | Deposit date: | 2020-03-27 | Release date: | 2021-04-07 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Titin kinase ubiquitination aligns autophagy receptors with mechanical signals in the sarcomere. Embo Rep., 22, 2021
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4J23
| Low resolution crystal structure of the FGFR2D2D3/FGF1/SR128545 complex | Descriptor: | Fibroblast growth factor 1, Fibroblast growth factor receptor 2 | Authors: | Kudlinzki, D, Saxena, K, Sreeramulu, S, Schieborr, U, Dreyer, M, Schreuder, H, Schwalbe, H. | Deposit date: | 2013-02-04 | Release date: | 2014-02-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.882 Å) | Cite: | Molecular mechanism of SSR128129E, an extracellularly acting, small-molecule, allosteric inhibitor of FGF receptor signaling. Cancer Cell, 23, 2013
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7ZA2
| GPC3-Unc5D octamer structure and role in cell migration | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glypican-3, ... | Authors: | Akkermans, O, Delloye-Bourgeois, C, Peregrina, C, Carrasquero, M, Kokolaki, M, Berbeira-Santana, M, Chavent, M, Reynaud, F, Ritu, R, Agirre, J, Aksu, M, White, E, Lowe, E, Ben Amar, D, Zaballa, S, Huo, J, Pakos, I, McCubbin, P, Comoletti, D, Owens, R, Robinson, C, Castellani, V, del Toro, D, Seiradake, E. | Deposit date: | 2022-03-21 | Release date: | 2022-11-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (4.6 Å) | Cite: | GPC3-Unc5 receptor complex structure and role in cell migration. Cell, 185, 2022
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7ZA1
| GPC3-Unc5D octamer structure and role in cell migration | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glypican-3, ... | Authors: | Akkermans, O, Delloye-Bourgeois, C, Peregrina, C, Carrasquero, M, Kokolaki, M, Berbeira-Santana, M, Chavent, M, Reynaud, F, Ritu, R, Agirre, J, Aksu, M, White, E, Lowe, E, Ben Amar, D, Zaballa, S, Huo, J, Pakos, I, McCubbin, P, Comoletti, D, Owens, R, Robinson, C, Castellani, V, del Toro, D, Seiradake, E. | Deposit date: | 2022-03-21 | Release date: | 2022-11-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | GPC3-Unc5 receptor complex structure and role in cell migration. Cell, 185, 2022
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7ZA3
| GPC3-Unc5D octamer structure and role in cell migration | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glypican-3, ... | Authors: | Akkermans, O, Delloye-Bourgeois, C, Peregrina, C, Carrasquero, M, Kokolaki, M, Berbeira-Santana, M, Chavent, M, Reynaud, F, Ritu, R, Agirre, J, Aksu, M, White, E, Lowe, E, Ben Amar, D, Zaballa, S, Huo, J, Pakos, I, McCubbin, P, Comoletti, D, Owens, R, Robinson, C, Castellani, V, del Toro, D, Seiradake, E. | Deposit date: | 2022-03-21 | Release date: | 2022-11-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | GPC3-Unc5 receptor complex structure and role in cell migration. Cell, 185, 2022
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8A1F
| Human PTPRK N-terminal domains MAM-Ig-FN1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Hay, I.M, Graham, S.C, Sharpe, H.J, Deane, J.E. | Deposit date: | 2022-06-01 | Release date: | 2023-03-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains. J.Biol.Chem., 299, 2023
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7LBF
| CryoEM structure of the HCMV Trimer gHgLgO in complex with human Platelet-derived growth factor receptor alpha and neutralizing fabs 13H11 and MSL-109 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, ... | Authors: | Kschonsak, M, Rouge, L, Arthur, C.P, Hoangdung, H, Patel, N, Kim, I, Johnson, M, Kraft, E, Rohou, A.L, Gill, A, Martinez-Martin, N, Payandeh, J, Ciferri, C. | Deposit date: | 2021-01-07 | Release date: | 2021-03-10 | Last modified: | 2021-03-17 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structures of HCMV Trimer reveal the basis for receptor recognition and cell entry. Cell, 184, 2021
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8BXR
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7LRG
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6U7N
| Crystal structure of neurotrimin (NTM) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Neurotrimin, ... | Authors: | Machius, M, Venkannagari, H, Misra, A, Rudenko, G, Rush, S. | Deposit date: | 2019-09-03 | Release date: | 2020-08-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.321 Å) | Cite: | Highly Conserved Molecular Features in IgLONs Contrast Their Distinct Structural and Biological Outcomes. J.Mol.Biol., 432, 2020
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3UTO
| Twitchin kinase region from C.elegans (Fn31-NL-kin-CRD-Ig26) | Descriptor: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CITRATE ANION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Castelmur, E, Barbieri, S, Mayans, O. | Deposit date: | 2011-11-26 | Release date: | 2012-08-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Identification of an N-terminal inhibitory extension as the primary mechanosensory regulator of twitchin kinase. Proc.Natl.Acad.Sci.USA, 109, 2012
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3V6B
| VEGFR-2/VEGF-E complex structure | Descriptor: | VEGF-E, Vascular endothelial growth factor receptor 2 | Authors: | Brozzo, M.S, Leppanen, V.-M, Winkler, F.K, Kisko, K, Ballmer-Hofer, K. | Deposit date: | 2011-12-19 | Release date: | 2012-01-18 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (3.205 Å) | Cite: | Thermodynamic and structural description of allosterically regulated VEGFR-2 dimerization. Blood, 119, 2012
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3V2A
| VEGFR-2/VEGF-A COMPLEX STRUCTURE | Descriptor: | Vascular endothelial growth factor A, Vascular endothelial growth factor receptor 2 | Authors: | Brozzo, M.S, Leppanen, V.-M, Winkler, F.K, Ballmer-Hofer, K. | Deposit date: | 2011-12-12 | Release date: | 2012-01-18 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (3.204 Å) | Cite: | Thermodynamic and structural description of allosterically regulated VEGFR-2 dimerization. Blood, 119, 2012
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5FTT
| Octameric complex of Latrophilin 3 (Lec, Olf) , Unc5D (Ig, Ig2, TSP1) and FLRT2 (LRR) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADHESION G PROTEIN-COUPLED RECEPTOR L3, CALCIUM ION, ... | Authors: | Jackson, V.A, Mehmood, S, Chavent, M, Roversi, P, Carrasquero, M, del Toro, D, Seyit-Bremer, G, Ranaivoson, F.M, Comoletti, D, Sansom, M.S.P, Robinson, C.V, Klein, R, Seiradake, E. | Deposit date: | 2016-01-15 | Release date: | 2016-05-04 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Super-Complexes of Adhesion Gpcrs and Neural Guidance Receptors Nat.Commun., 7, 2016
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5FM5
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5T89
| Crystal structure of VEGF-A in complex with VEGFR-1 domains D1-6 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Vascular endothelial growth factor A, ... | Authors: | Markovic-Mueller, S, Stuttfeld, E, Asthana, M, Weinert, T, Bliven, S, Goldie, K.N, Kisko, K, Capitani, G, Ballmer-Hofer, K. | Deposit date: | 2016-09-07 | Release date: | 2017-02-01 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Structure of the Full-length VEGFR-1 Extracellular Domain in Complex with VEGF-A. Structure, 25, 2017
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5UV6
| Crystal structure of human Opioid Binding Protein/Cell Adhesion Molecule Like (OPCML) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Opioid-binding protein/cell adhesion molecule, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Birtley, J.R, Stern, L.J, Gabra, H, Zanini, E. | Deposit date: | 2017-02-19 | Release date: | 2018-03-21 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.65002 Å) | Cite: | Inactivating mutations and X-ray crystal structure of the tumor suppressor OPCML reveal cancer-associated functions. Nat Commun, 10, 2019
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8K53
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