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2YD6
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BU of 2yd6 by Molmil
Crystal structure of the N-terminal Ig1-2 module of Human Receptor Protein Tyrosine Phosphatase Delta
Descriptor: CHLORIDE ION, CITRATE ANION, PTPRD PROTEIN
Authors:Coles, C.H, Shen, Y, Tenney, A.P, Siebold, C, Sutton, G.C, Lu, W, Gallagher, J.T, Jones, E.Y, Flanagan, J.G, Aricescu, A.R.
Deposit date:2011-03-17
Release date:2011-04-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Proteoglycan-Specific Molecular Switch for Rptp Sigma Clustering and Neuronal Extension.
Science, 332, 2011
2YD7
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BU of 2yd7 by Molmil
Crystal structure of the N-terminal Ig1-2 module of Human Receptor Protein Tyrosine Phosphatase Delta
Descriptor: PHOSPHATE ION, PTPRD PROTEIN
Authors:Coles, C.H, Shen, Y, Tenney, A.P, Siebold, C, Sutton, G.C, Lu, W, Gallagher, J.T, Jones, E.Y, Flanagan, J.G, Aricescu, A.R.
Deposit date:2011-03-17
Release date:2011-04-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Proteoglycan-Specific Molecular Switch for Rptp Sigma Clustering and Neuronal Extension.
Science, 332, 2011
7CEG
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BU of 7ceg by Molmil
Crystal structure of the complex between mouse PTP delta and neuroligin-3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform C of Receptor-type tyrosine-protein phosphatase delta, Neuroligin-3
Authors:Yamagata, A, Yoshida, T, Shiroshima, T, Maeda, A, Fukai, S.
Deposit date:2020-06-23
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.85 Å)
Cite:Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice.
Nat Commun, 12, 2021
8S9P
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BU of 8s9p by Molmil
1:1:1 agrin/LRP4/MuSK complex
Descriptor: Agrin, Low-density lipoprotein receptor-related protein 4, Muscle, ...
Authors:Xie, T, Xu, G.J, Liu, Y, Quade, B, Lin, W.C, Bai, X.C.
Deposit date:2023-03-29
Release date:2023-05-17
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural insights into the assembly of the agrin/LRP4/MuSK signaling complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
8G4L
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BU of 8g4l by Molmil
Cryo-EM structure of the human cardiac myosin filament
Descriptor: Myosin light chain 3, Myosin regulatory light chain 2, ventricular/cardiac muscle isoform, ...
Authors:Dutta, D, Nguyen, V, Padron, R, Craig, R.
Deposit date:2023-02-10
Release date:2023-11-01
Last modified:2023-12-06
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:Cryo-EM structure of the human cardiac myosin filament.
Nature, 623, 2023
7OL4
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BU of 7ol4 by Molmil
Mouse contactin-1 neurofascin-155 immunoglobulin domains adhesion complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Contactin-1, Neurofascin, ...
Authors:Chataigner, L.M.P, Janssen, B.J.C.
Deposit date:2021-05-19
Release date:2022-12-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (4.8 Å)
Cite:Structural insights into the contactin 1 - neurofascin 155 adhesion complex.
Nat Commun, 13, 2022
7OL2
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BU of 7ol2 by Molmil
Crystal structure of mouse contactin 1 immunoglobulin domains
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Contactin-1, ...
Authors:Chataigner, L.M.P, Janssen, B.J.C.
Deposit date:2021-05-19
Release date:2022-12-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.89 Å)
Cite:Structural insights into the contactin 1 - neurofascin 155 adhesion complex.
Nat Commun, 13, 2022
6YGN
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BU of 6ygn by Molmil
Titin kinase and its flanking domains
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Titin
Authors:Fleming, J.R, Franke, B, Bogomolovas, J, Mayans, O.
Deposit date:2020-03-27
Release date:2021-04-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Titin kinase ubiquitination aligns autophagy receptors with mechanical signals in the sarcomere.
Embo Rep., 22, 2021
4J23
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BU of 4j23 by Molmil
Low resolution crystal structure of the FGFR2D2D3/FGF1/SR128545 complex
Descriptor: Fibroblast growth factor 1, Fibroblast growth factor receptor 2
Authors:Kudlinzki, D, Saxena, K, Sreeramulu, S, Schieborr, U, Dreyer, M, Schreuder, H, Schwalbe, H.
Deposit date:2013-02-04
Release date:2014-02-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.882 Å)
Cite:Molecular mechanism of SSR128129E, an extracellularly acting, small-molecule, allosteric inhibitor of FGF receptor signaling.
Cancer Cell, 23, 2013
7ZA2
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BU of 7za2 by Molmil
GPC3-Unc5D octamer structure and role in cell migration
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glypican-3, ...
Authors:Akkermans, O, Delloye-Bourgeois, C, Peregrina, C, Carrasquero, M, Kokolaki, M, Berbeira-Santana, M, Chavent, M, Reynaud, F, Ritu, R, Agirre, J, Aksu, M, White, E, Lowe, E, Ben Amar, D, Zaballa, S, Huo, J, Pakos, I, McCubbin, P, Comoletti, D, Owens, R, Robinson, C, Castellani, V, del Toro, D, Seiradake, E.
Deposit date:2022-03-21
Release date:2022-11-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (4.6 Å)
Cite:GPC3-Unc5 receptor complex structure and role in cell migration.
Cell, 185, 2022
7ZA1
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BU of 7za1 by Molmil
GPC3-Unc5D octamer structure and role in cell migration
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glypican-3, ...
Authors:Akkermans, O, Delloye-Bourgeois, C, Peregrina, C, Carrasquero, M, Kokolaki, M, Berbeira-Santana, M, Chavent, M, Reynaud, F, Ritu, R, Agirre, J, Aksu, M, White, E, Lowe, E, Ben Amar, D, Zaballa, S, Huo, J, Pakos, I, McCubbin, P, Comoletti, D, Owens, R, Robinson, C, Castellani, V, del Toro, D, Seiradake, E.
Deposit date:2022-03-21
Release date:2022-11-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:GPC3-Unc5 receptor complex structure and role in cell migration.
Cell, 185, 2022
7ZA3
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BU of 7za3 by Molmil
GPC3-Unc5D octamer structure and role in cell migration
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glypican-3, ...
Authors:Akkermans, O, Delloye-Bourgeois, C, Peregrina, C, Carrasquero, M, Kokolaki, M, Berbeira-Santana, M, Chavent, M, Reynaud, F, Ritu, R, Agirre, J, Aksu, M, White, E, Lowe, E, Ben Amar, D, Zaballa, S, Huo, J, Pakos, I, McCubbin, P, Comoletti, D, Owens, R, Robinson, C, Castellani, V, del Toro, D, Seiradake, E.
Deposit date:2022-03-21
Release date:2022-11-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (4 Å)
Cite:GPC3-Unc5 receptor complex structure and role in cell migration.
Cell, 185, 2022
8A1F
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BU of 8a1f by Molmil
Human PTPRK N-terminal domains MAM-Ig-FN1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Hay, I.M, Graham, S.C, Sharpe, H.J, Deane, J.E.
Deposit date:2022-06-01
Release date:2023-03-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains.
J.Biol.Chem., 299, 2023
7LBF
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BU of 7lbf by Molmil
CryoEM structure of the HCMV Trimer gHgLgO in complex with human Platelet-derived growth factor receptor alpha and neutralizing fabs 13H11 and MSL-109
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, ...
Authors:Kschonsak, M, Rouge, L, Arthur, C.P, Hoangdung, H, Patel, N, Kim, I, Johnson, M, Kraft, E, Rohou, A.L, Gill, A, Martinez-Martin, N, Payandeh, J, Ciferri, C.
Deposit date:2021-01-07
Release date:2021-03-10
Last modified:2021-03-17
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structures of HCMV Trimer reveal the basis for receptor recognition and cell entry.
Cell, 184, 2021
8BXR
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BU of 8bxr by Molmil
Titin FnIII-domain I109-I111 (I/A4-A/A6) from the MIR region
Descriptor: 1,2-ETHANEDIOL, Titin
Authors:Mayans, O, Fleming, J.R, Williams, R.
Deposit date:2022-12-09
Release date:2023-02-15
Last modified:2023-03-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Immunological and Structural Characterization of Titin Main Immunogenic Region; I110 Domain Is the Target of Titin Antibodies in Myasthenia Gravis.
Biomedicines, 11, 2023
7LRG
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BU of 7lrg by Molmil
Filamentous actin decorated with human cardiac myosin binding protein C C2 domain
Descriptor: Actin, alpha cardiac muscle 1, Myosin-binding protein C, ...
Authors:Galkin, V.E.
Deposit date:2021-02-16
Release date:2021-08-11
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Interaction of the C2 Ig-like Domain of Cardiac Myosin Binding Protein-C with F-actin.
J.Mol.Biol., 433, 2021
6U7N
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BU of 6u7n by Molmil
Crystal structure of neurotrimin (NTM)
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Neurotrimin, ...
Authors:Machius, M, Venkannagari, H, Misra, A, Rudenko, G, Rush, S.
Deposit date:2019-09-03
Release date:2020-08-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.321 Å)
Cite:Highly Conserved Molecular Features in IgLONs Contrast Their Distinct Structural and Biological Outcomes.
J.Mol.Biol., 432, 2020
3UTO
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BU of 3uto by Molmil
Twitchin kinase region from C.elegans (Fn31-NL-kin-CRD-Ig26)
Descriptor: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CITRATE ANION, DI(HYDROXYETHYL)ETHER, ...
Authors:Castelmur, E, Barbieri, S, Mayans, O.
Deposit date:2011-11-26
Release date:2012-08-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Identification of an N-terminal inhibitory extension as the primary mechanosensory regulator of twitchin kinase.
Proc.Natl.Acad.Sci.USA, 109, 2012
3V6B
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BU of 3v6b by Molmil
VEGFR-2/VEGF-E complex structure
Descriptor: VEGF-E, Vascular endothelial growth factor receptor 2
Authors:Brozzo, M.S, Leppanen, V.-M, Winkler, F.K, Kisko, K, Ballmer-Hofer, K.
Deposit date:2011-12-19
Release date:2012-01-18
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.205 Å)
Cite:Thermodynamic and structural description of allosterically regulated VEGFR-2 dimerization.
Blood, 119, 2012
3V2A
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BU of 3v2a by Molmil
VEGFR-2/VEGF-A COMPLEX STRUCTURE
Descriptor: Vascular endothelial growth factor A, Vascular endothelial growth factor receptor 2
Authors:Brozzo, M.S, Leppanen, V.-M, Winkler, F.K, Ballmer-Hofer, K.
Deposit date:2011-12-12
Release date:2012-01-18
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.204 Å)
Cite:Thermodynamic and structural description of allosterically regulated VEGFR-2 dimerization.
Blood, 119, 2012
5FTT
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BU of 5ftt by Molmil
Octameric complex of Latrophilin 3 (Lec, Olf) , Unc5D (Ig, Ig2, TSP1) and FLRT2 (LRR)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADHESION G PROTEIN-COUPLED RECEPTOR L3, CALCIUM ION, ...
Authors:Jackson, V.A, Mehmood, S, Chavent, M, Roversi, P, Carrasquero, M, del Toro, D, Seyit-Bremer, G, Ranaivoson, F.M, Comoletti, D, Sansom, M.S.P, Robinson, C.V, Klein, R, Seiradake, E.
Deposit date:2016-01-15
Release date:2016-05-04
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Super-Complexes of Adhesion Gpcrs and Neural Guidance Receptors
Nat.Commun., 7, 2016
5FM5
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BU of 5fm5 by Molmil
Crystal structure of the myomesin:obscurin-like-1 complex
Descriptor: MYOMESIN-1, OBSCURIN-LIKE-1
Authors:Pernigo, S, Steiner, R.A.
Deposit date:2015-11-01
Release date:2016-11-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection.
Structure, 25, 2017
5T89
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BU of 5t89 by Molmil
Crystal structure of VEGF-A in complex with VEGFR-1 domains D1-6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Vascular endothelial growth factor A, ...
Authors:Markovic-Mueller, S, Stuttfeld, E, Asthana, M, Weinert, T, Bliven, S, Goldie, K.N, Kisko, K, Capitani, G, Ballmer-Hofer, K.
Deposit date:2016-09-07
Release date:2017-02-01
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structure of the Full-length VEGFR-1 Extracellular Domain in Complex with VEGF-A.
Structure, 25, 2017
5UV6
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BU of 5uv6 by Molmil
Crystal structure of human Opioid Binding Protein/Cell Adhesion Molecule Like (OPCML)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Opioid-binding protein/cell adhesion molecule, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Birtley, J.R, Stern, L.J, Gabra, H, Zanini, E.
Deposit date:2017-02-19
Release date:2018-03-21
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.65002 Å)
Cite:Inactivating mutations and X-ray crystal structure of the tumor suppressor OPCML reveal cancer-associated functions.
Nat Commun, 10, 2019
8K53
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BU of 8k53 by Molmil
Structure of the Dimeric Human CNTN2 Ig 1-6-FNIII 1-2 Domain in an Asymmetric State
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Contactin-2, ...
Authors:Zhang, Z.Z.
Deposit date:2023-07-21
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of human CNTN2 immunoglobulin domains 1-6 homo-dimer
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